scholarly journals Night sleep duration and risk of each lipid profile abnormality in a Chinese population: a prospective cohort study

2020 ◽  
Author(s):  
Qiaofeng Song ◽  
Xiaoxue Liu ◽  
Wenhua Zhou ◽  
Shouling Wu ◽  
xizhu wang
Keyword(s):  
Lipid Profile ◽  
Sleep Duration ◽  
Chinese Population ◽  
Serum Lipid ◽  
Lipid Level ◽  
Density Lipoprotein ◽  
Serum Lipid Level ◽  
Cox Proportional Hazards Model ◽  
Lipoprotein Cholesterol ◽  
Low Hdl

Abstract Background To explore the associations between sleep duration and abnormalities in each serum lipid level in a Chinese population. Methods A prospective study was conducted with 33,817 participants from the general Chinese population. Sleep duration was categorized as ≤5, 6, 7, 8 or ≥9 h. Each lipid profile abnormality was defined according to the Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults. The Cox proportional hazards model was used to assess these associations. Results Compared with a seven-hour sleep duration, longer sleep duration was significantly associated with high low-density lipoprotein cholesterol (LDL-C) (HR: 1.18; 95% CI: 1.10–1.17) in fully adjusted models. And a longer sleep duration was significantly associated with low high-density lipoprotein cholesterol (HDL-C) levels (HR: 1.22; 95% CI: 1.19–1.35). In subgroup analyses, the positive association between long sleep duration and high LDL-C and low HDL-C levels in men and in the different age groups were more pronounced than the association in women. No significant interactions were observed in the association between sleep duration and each abnormal serum lipid level by sex/age in the study population(p- interaction>0.05). Conclusions These findings suggest that longer sleep duration is associated with high LDL-C and low HDL-C levels among the Chinese population.

scholarly journals Night sleep duration and risk of each lipid profile abnormality in a Chinese population: a prospective cohort study

2020 ◽  
Author(s):  
Qiaofeng Song ◽  
Xiaoxue Liu ◽  
Wenhua Zhou ◽  
Shouling Wu ◽  
xizhu wang
Keyword(s):  
Lipid Profile ◽  
Sleep Duration ◽  
Chinese Population ◽  
Serum Lipid ◽  
Proportional Hazards Model ◽  
Lipid Level ◽  
Serum Lipid Level ◽  
Cox Proportional Hazards ◽  
Cox Proportional Hazards Model ◽  
Low Hdl

Abstract Background To explore the associations between sleep duration and abnormalities in each serum lipid level in a Chinese population. Methods A prospective study was conducted with 34,260 participants from the general Chinese population. Sleep duration was categorized as ≤5, 6, 7, 8 or ≥9 h. Each lipid profile abnormality was defined according to the Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults(2016). The Cox proportional hazards model was used to assess these associations. Results Compared with a seven-hour sleep duration, longer sleep duration was significantly associated with low high-density lipoprotein cholesterol (HDL-C) levels (HR: 1.24; 95% CI: 1.12–1.38). In subgroup analyses, the positive association between long sleep duration and low HDL-C levels in men and in the different age groups were more pronounced than the association in women. No significant interactions were observed in the association between sleep duration and each abnormal serum lipid level by sex/age in the study population(p- interaction>0.05). Conclusions These findings suggest that longer sleep duration is associated with low HDL-C levels among the Chinese population.

scholarly journals Night sleep duration and risk of each lipid profile abnormality in a Chinese population: a prospective cohort study

2020 ◽  
Author(s):  
Qiaofeng Song ◽  
Xiaoxue Liu ◽  
Wenhua Zhou ◽  
Shouling Wu ◽  
Xizhu Wang
Keyword(s):  
Lipid Profile ◽  
Sleep Duration ◽  
Chinese Population ◽  
Serum Lipid ◽  
Proportional Hazards Model ◽  
Lipid Level ◽  
Serum Lipid Level ◽  
Cox Proportional Hazards Model ◽  
Long Sleep ◽  
Low Hdl

Abstract Background To explore the associations between sleep duration and abnormalities in each serum lipid level in a Chinese population. Methods A prospective study was conducted with 34,260 participants from the general Chinese population. Sleep duration was categorized as ≤5, 6, 7, 8 or ≥9 h. Each lipid profile abnormality was defined according to the Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults (2016). The Cox proportional hazards model was used to assess these associations. Results Compared with a 7 h sleep duration, long sleep duration (≥9 h) was significantly associated with low high-density lipoprotein cholesterol (HDL-C) levels (hazard ratio (HR): 1.24; 95% CI: 1.12–1.38). In subgroup analyses, the positive association between long sleep duration and low HDL-C levels in men and in the different age groups were more pronounced than the association in women. No significant interactions were observed in the association between sleep duration and each abnormal serum lipid level by sex/age in the study population( P - interaction>0.05). Conclusions These findings suggest that long sleep duration is associated with low HDL-C levels among the Kailuan community population.

scholarly journals Night sleep duration and risk of each lipid profile abnormality in a Chinese population: a prospective cohort study

2020 ◽  
Author(s):  
Qiaofeng Song ◽  
Xiaoxue Liu ◽  
Wenhua Zhou ◽  
Shouling Wu ◽  
xizhu wang
Keyword(s):  
Lipid Profile ◽  
Sleep Duration ◽  
Chinese Population ◽  
Serum Lipid ◽  
Proportional Hazards Model ◽  
Lipid Level ◽  
Cox Proportional Hazards ◽  
Cox Proportional Hazards Model ◽  
Long Sleep ◽  
Low Hdl

Abstract Background To explore the associations between sleep duration and abnormalities in serum lipid levels in a Chinese population. Methods A prospective study was conducted with 34,260 participants from the general Chinese population. Sleep duration was categorized as ≤5, 6, 7, 8 or ≥9 h. Each lipid profile abnormality was defined according to the Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults (2016). The Cox proportional hazards model was used to assess the association between sleep duration and dyslipidemia. Results Compared with a 7 h sleep duration, long sleep duration (≥9 h) was significantly associated with low high-density lipoprotein cholesterol (HDL-C) levels (hazard ratio (HR): 1.24; 95% CI: 1.12–1.38). In subgroup analyses, the positive association between long sleep duration and low HDL-C level in men and in the different age groups was more pronounced than the association in women. No significant interactions were observed in the association between sleep duration and each abnormal serum lipid level by sex/age in the study population (P-interaction>0.05). Conclusions These findings suggest that long sleep duration is associated with low HDL-C level among the Kailuan community population.

scholarly journals Night sleep duration and risk of each lipid profile abnormality in a Chinese population: a prospective cohort study

2020 ◽  
Author(s):  
Qiaofeng Song ◽  
Xiaoxue Liu ◽  
Wenhua Zhou ◽  
Shouling Wu ◽  
xizhu wang
Keyword(s):  
Lipid Profile ◽  
Sleep Duration ◽  
Chinese Population ◽  
Serum Lipid ◽  
Proportional Hazards Model ◽  
Lipid Level ◽  
Cox Proportional Hazards ◽  
Cox Proportional Hazards Model ◽  
Long Sleep ◽  
Low Hdl

Abstract Background To explore the associations between sleep duration and abnormalities in serum lipid levels in a Chinese population. Methods A prospective study was conducted with 34,260 participants from the general Chinese population. Sleep duration was categorized as ≤5, 6, 7, 8 or ≥9 h. Each lipid profile abnormality was defined according to the Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults (2016). The Cox proportional hazards model was used to assess the association between sleep duration and dyslipidemia. Results Compared with a 7 h sleep duration, long sleep duration (≥9 h) was significantly associated with low high-density lipoprotein cholesterol (HDL-C) levels (hazard ratio (HR): 1.24; 95% CI: 1.12–1.38). In subgroup analyses, the positive association between long sleep duration and low HDL-C level in men and in the different age groups was more pronounced than the association in women. No significant interactions were observed in the association between sleep duration and each abnormal serum lipid level by sex/age in the study population (P-interaction>0.05). Conclusions These findings suggest that long sleep duration is associated with low HDL-C level among the Kailuan community population.

scholarly journals Night sleep duration and risk of each lipid profile abnormality in a Chinese population: a prospective cohort study

2020 ◽  
Author(s):  
Qiaofeng Song ◽  
Xiaoxue Liu ◽  
Wenhua Zhou ◽  
Shouling Wu ◽  
xizhu wang
Keyword(s):  
Lipid Profile ◽  
Sleep Duration ◽  
Chinese Population ◽  
Serum Lipid ◽  
Proportional Hazards Model ◽  
Lipid Level ◽  
Cox Proportional Hazards ◽  
Cox Proportional Hazards Model ◽  
Long Sleep ◽  
Low Hdl

Abstract Background To explore the associations between sleep duration and abnormalities in serum lipid levels in a Chinese population. Methods A prospective study was conducted with 34,260 participants from the general Chinese population. Sleep duration was categorized as ≤5, 6, 7, 8 or ≥9 h. Each lipid profile abnormality was defined according to the Chinese Guidelines for the Prevention and Treatment of Dyslipidemia in Adults (2016). The Cox proportional hazards model was used to assess the association between sleep duration and dyslipidemia. Results Compared with a 7 h sleep duration, long sleep duration (≥9 h) was significantly associated with low high-density lipoprotein cholesterol (HDL-C) levels (hazard ratio (HR): 1.24; 95% CI: 1.12–1.38). In subgroup analyses, the positive association between long sleep duration and low HDL-C level in men and in the different age groups was more pronounced than the association in women. No significant interactions were observed in the association between sleep duration and each abnormal serum lipid level by sex/age in the study population (P-interaction>0.05). Conclusions These findings suggest that long sleep duration is associated with low HDL-C level among the Kailuan community population.

scholarly journals Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea : A propensity score analysis

2021 ◽  
Author(s):  
Minji Ha ◽  
Jiyun Song ◽  
Sunkyoung Park ◽  
Kyungdo Han ◽  
Ho Sik Hwang ◽  
...  
Keyword(s):  
General Population ◽  
Propensity Score ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Lipid Level ◽  
Density Lipoprotein ◽  
Serum Lipid Level ◽  
Meibomian Gland ◽  
Meibomian Gland Dysfunction ◽  
The Mean

Abstract Purpose: To analyze the correlation between systemic lipid profile levels and each meibomian gland dysfunction (MGD) subtype in Korea.Methods: The ophthalmic data of 95 eyes and the serum lipid profiles of 95 patients were reviewed. These factors were compared with those of the general population using data from the Korean National Health and Nutrition Examination Survey (KNHANES), which evaluated 2,924 subjects. Of these, 475 propensity score-matched normal controls were selected for comparison with the 95 MGD patients based on a 1:5 ratio. In addition, we analyzed the correlations between serum lipid profile levels and MGD subtypes in MGD patients.Results: The mean high-density lipoprotein (HDL) value of the MGD patients was significantly higher than that of the general population (P < 0.0001). However, the mean total cholesterol (TC), triglyceride (TG), and low-density lipoprotein (LDL) levels of the MGD patients were not significantly different from those of the general population (TC: P = 0.3950, TG: P = 0.6331, LDL: P = 0.2079). In addition, no serum lipid levels statistically differed among the MGD subtypes (TC: P = 0.7650, HDL: P = 0.2480, LDL: P = 0.3430, TG: P = 0.7030).Conclusion: A statistically significant, but marginal, increase in HDL concentration was observed in the MGD group, although there was no difference in any serum lipid level among the MGD subtypes.

scholarly journals Association between self-reported sleep duration and serum lipid profile in a middle-aged and elderly population in Taiwan: a community-based, cross-sectional study

BMJ Open ◽  
2017 ◽  
Vol 7 (10) ◽  
pp. e015964 ◽  
Author(s):  
Pu Lin ◽  
Kai-Ting Chang ◽  
Yan-An Lin ◽  
I-Shiang Tzeng ◽  
Hai-Hua Chuang ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Lipid Profile ◽  
Sleep Duration ◽  
Serum Lipid ◽  
Density Lipoprotein ◽  
Multivariate Logistic Regression ◽  
Middle Aged ◽  
Community Based ◽  
Cross Sectional ◽  
Low Hdl

ObjectivesThe association between sleep duration and serum lipid profile in the middle-aged and the elderly is unclear. The aim of this study was to investigate and evaluate the relationships between sleep duration and levels of serum total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol (HDL-C) and triglycerides in these populations.DesignCross-sectional observational study.SettingCommunity-based investigation in Guishan Township of northern Taiwan.ParticipantsA total of 400 community-dwelling middle-aged and elderly individuals were enrolled. All participants underwent a baseline assessment in 2014, which included anthropometrics, blood samples and self-administered questionnaires. Participants were classified into three groups based on their sleep duration.Outcome measuresMultivariate logistic regression was used to obtain ORs and 95% CIs to assess the relationship between sleep duration and lipid profiles.ResultsParticipant mean age was 64.5 years and 35.3% were men. Subjects with longer (>7 hours) and shorter (<6 hours) nightly sleep duration had a higher prevalence of low HDL-C levels (HDL <40 mg/dL) than those with moderate sleep duration (6–7 hours). Multivariate logistic regression revealed that, compared with individuals with sleep duration of 6–7 hours, the ORs of having low HDL-C were 3.68 (95% CI 1.59 to 8.49) greater for individuals with sleep duration of <6 hours and 2.89 (95% CI 1.10 to 7.61) greater for individuals with sleep duration of >7 hours.ConclusionsThere was a U-shaped relationship between sleep duration and HDL-C levels. Sleep duration >7 hours or <6 hours increased the risk of low serum HDL-C levels.

scholarly journals Relationship between serum lipid level and meibomian gland dysfunction subtype in Korea using propensity score matching

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Minji Ha ◽  
Jiyun Song ◽  
Sunkyoung Park ◽  
Kyungdo Han ◽  
Ho Sik Hwang ◽  
...  
Keyword(s):  
General Population ◽  
Propensity Score ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Lipid Level ◽  
Density Lipoprotein ◽  
Serum Lipid Level ◽  
Meibomian Gland ◽  
The Mean ◽  
The Relationship

AbstractTo analyze the relationship between systemic lipid profile levels and meibomian gland dysfunction (MGD) subtype in Korea. The ophthalmic data of 95 eyes and the serum lipid profiles of 95 patients were reviewed. These factors were compared with those of the general population using data from the Korean National Health and Nutrition Examination Survey (KNHANES), which evaluated 2,917 subjects. Of these, the comparison group (1:5 ratio; n = 475) was selected using propensity score matching according to age and sex. In addition, we analyzed the relationship between serum lipid profile levels and MGD subtypes in MGD patients. The mean high-density lipoprotein (HDL) value of the MGD patients was significantly higher than that of the general population (P < 0.0001). Moreover, the mean low-density lipoprotein (LDL) levels of the MGD patients was significantly lower than that of the general population (P = 0.0002). However, the mean total cholesterol (TC), and triglyceride (TG) levels of the MGD patients were not significantly different from those of the general population (TC: P = 0.4282, TG: P = 0.5613). In addition, no serum lipid levels statistically differed among the MGD subtypes (TC: P = 0.7650, HDL: P = 0.2480, LDL: P = 0.3430, TG: P = 0.7030). A statistically significant increase in HDL and decrease in LDL concentration were observed in the MGD group, although there was no difference in any serum lipid level among the MGD subtypes.

scholarly journals Executive functioning and serum lipid fractions in Parkinson’s disease—a possible sex-effect: the PACOS study

2022 ◽  
Author(s):  
Antonina Luca ◽  
Roberto Monastero ◽  
Calogero Edoardo Cicero ◽  
Roberta Baschi ◽  
Giulia Donzuso ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Executive Functioning ◽  
Lipid Profile ◽  
Serum Lipid ◽  
Density Lipoprotein ◽  
Positive Association ◽  
Executive Dysfunction ◽  
Lipoprotein Cholesterol ◽  
Lipid Fractions

AbstractThe association between dyslipidemia and cognitive performance in Parkinson’s disease (PD) patients still needs to be clarified. Aim of the study was to evaluate the presence of possible associations between serum lipids fractions and executive dysfunction also exploring the sex-specific contribute of lipids level on cognition. Patients from the PACOS cohort, who underwent a complete serum lipid profile measures (total cholesterol-TC, low-density lipoprotein cholesterol-LDL, high-density lipoprotein cholesterol-HDL and triglycerides-TG) were selected. Adult Treatment Panel III guidelines of the National Cholesterol Education Program were used to classify normal/abnormal lipid fractions. Executive functioning was assessed with the Frontal Assessment Battery (FAB). Logistic regression was performed to assess associations between lipids fractions and FAB score. Correlations between lipids fractions and FAB score were explored. Sex-stratified analysis was performed. Three hundred and forty-eight PD patients (148 women; age 66.5 ± 9.5 years; disease duration 3.9 ± 4.9 years) were enrolled. Women presented significantly higher TC, LDL and HDL than men. In the whole sample, any association between lipid profile measures and FAB score was found. Among women, a positive association between hypertriglyceridemia and FAB score under cutoff was found (OR 3.4; 95%CI 1.29–9.03; p value 0.013). A statistically significant negative correlation was found between the FAB score and triglyceride serum levels (r = − 0.226; p value 0.005). Differently, among men, a statistically significant negative association between hypercholesterolemia and FAB score under cutoff (OR 0.4; 95%CI 0.17–0.84; p value 0.018) and between high LDL levels and FAB score under cutoff (OR 0.4; 95%CI 0.18–0.90; p value 0.027) were found. Our data suggest a sex-specific different role of lipids in executive functioning.

scholarly journals Study of gallbladder lesions and its relationship with serum lipid profile

2018 ◽  
Vol 5 (5) ◽  
pp. 1245
Author(s):  
Sushama Bhatta ◽  
Samir Singh
Keyword(s):  
Lipid Profile ◽  
Serum Lipid ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Chronic Cholecystitis ◽  
Lipoprotein Cholesterol ◽  
Serum Lipid Profile ◽  
P Value ◽  
Low Density Lipoprotein Cholesterol ◽  
Histopathological Lesion

Background: Gallbladder disease is one of the most common gastrointestinal diseases. Various studies have shown association between gallstone and alteration in serum lipids. The objective of this study was to evaluate histological patterns of cholecystectomy specimens and compare serum lipid profile of gallstone patients with controls.Methods: This study was conducted over a period of two years (April 2016 to April 2018). Records of 287 specimens who underwent cholecystectomy were analysed in which gallstones were found only in 186 patients. Out of 186 patients with gallstones, records of serum lipid profile were available in 32 patients which were compared with 32 control of similar age. Independent t- test was used to compare the data between cases and control.Results: Out of 287 cases, 68 were male and 219 were female with male to female ratio of 1:3.2. The predominant histopathological lesion was chronic cholecystitis (73.17%). Malignancy was observed in 0.7% cases. Serum total cholesterol, triglycerides and low density lipoprotein cholesterol were found to be higher and statistically significant in patients with gallstone compared to controls (p value 0.024, <0.001and 0.016 respectively). Serum High density lipoprotein cholesterol was lower in gallstone patient than in control but not statistically significant (p value 0.23).Conclusions: Chronic cholecystitis was the most common histopathological lesion. Serum total cholesterol, triglyceride and low density lipoprotein cholesterol level were elevated and statistically significant in patients with gallstone.

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