scholarly journals A case study of the first pregnant women with COVID-19 in Bukavu, Eastern DR Congo

Author(s):  
ETIENNE KAJIBWAMI BIRINDWA ◽  
Guy MULINGANYA MULUMEODERHWA ◽  
Olivier NYAKIO ◽  
Guy Quesney MATESO MBALE ◽  
Serge ZIGABE MUSHAMUKA ◽  
...  

Abstract Introduction: Vertical transmission of covid-19 is possible; its risk factors are worth researching. The placental changes found in pregnant women have a definite impact on the foetus.Case presentation: We report a case of a 25-year-old woman, gravida 3, para 2 (2 alive children), with a history of two caesarean deliveries, who was infected by the SARS-Cov-2 during the last term of her pregnancy. She gave birth by caesarean after 34 weeks of gestation to a new-born baby also infected with SARS-Cov-2. The per-operative observations noted several eruptive lesions in the pelvis, bleeding on contact. Microscopic examination of the foetal appendages revealed thrombotic vasculopathy in the placenta and in the umbilical cord vessels.Conclusion: This case is one of the first documented cases of COVID-19 in pregnancy in sub-Saharan Africa. We strongly suggest obstetricians to carefully examine the aspect of the peritoneum, viscera and foetal appendages in affected pregnant women.

2020 ◽  
Author(s):  
Etienne KAJIBWAMI BIRINDWA ◽  
Guy MULINGANYA MULUMEODERHWA ◽  
Olivier NYAKIO ◽  
Guy-Quesney MATESO MBALE ◽  
Serge ZIGABE MUSHAMUKA ◽  
...  

Abstract Introduction: Vertical transmission of covid-19 is possible; its risk factors are worth researching. The placental changes found in pregnant women have a definite impact on the foetus.Case presentation: We report a case of a 25-year-old woman, gravida 3, para 2 (2 alive children), with a history of two caesarean deliveries, who was infected by the SARS-Cov-2 during the last term of her pregnancy. She gave birth by caesarean after 34 weeks of gestation to a new-born baby also infected with SARS-Cov-2. The per-operative observations noted several eruptive lesions in the pelvis, bleeding on contact. Microscopic examination of the foetal appendages revealed thrombotic vasculopathy in the placenta and in the umbilical cord vessels.Conclusion: This case is one of the first documented cases of COVID-19 in pregnancy in sub-Saharan Africa. We strongly suggest obstetricians to carefully examine the aspect of the peritoneum, viscera and foetal appendages in affected pregnant women.


Author(s):  
Etienne Kajibwami Birindwa ◽  
Guy Mulinganya Mulumeoderhwa ◽  
Olivier Nyakio ◽  
Guy-Quesney Mateso Mbale ◽  
Serge Zigabe Mushamuka ◽  
...  

Abstract Introduction Vertical transmission of covid-19 is possible; its risk factors are worth researching. The placental changes found in pregnant women have a definite impact on the foetus. Case presentation We report a case of a 25-year-old woman, gravida 3, para 2 (2 alive children), with a history of two caesarean deliveries, who was infected by the SARS-CoV-2 during the last term of her pregnancy. She gave birth by caesarean at 34 weeks of gestation to a newborn baby also infected with SARS-CoV-2. The peri-operative observations noted several eruptive lesions in the pelvis, bleeding on contact. Microscopic examination of the foetal appendages revealed thrombotic vasculopathy in the placenta and in the umbilical cord vessels. Conclusion This case is one of the first documented cases of COVID-19 in pregnancy in sub-Saharan Africa. We strongly suggest obstetricians to carefully examine the aspect of the peritoneum, viscera and foetal appendages in affected pregnant women.


Author(s):  
Chibuzo Christian Uba ◽  
Moses Nkechukwu Ikegbunam ◽  
Emmanuel Chigozie Udegbunam ◽  
Chioma Abana ◽  
Stephen Nnaemeka Ezekwueche ◽  
...  

Each year, an estimated number of 300–500 million people are infected with malaria parasite, with an undesirable effect of over one million deaths. Pregnant women as well as young children, non-immune travellers visiting malaria-endemic zones are at the highest risk of suffering or experiencing life - threatening malaria infection. Maternal immunity, parasite density, parity, inadequate antenatal care services, drug misuse and abuse as well intermitted preventive treatment drug failure cum resistance are the most associated risk factors of malaria in pregnancy obtainable in endemic regions of sub-Saharan Africa. Identification and understanding of these factors will play a major role in reducing the burden as well as eliminating malaria disease among pregnant women living in endemic regions.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
R. S. Houmsou ◽  
B. E. Wama ◽  
S. O. Elkanah ◽  
L. C. Garba ◽  
T. D. Hile ◽  
...  

Malaria still remains a challenging infection affecting the lives of several HIV infected pregnant women in sub-Saharan Africa. This study was undertaken to determine malarial infection in HIV infected pregnant women in relation to sociodemographic and obstetrical factors. The study also assessed relationship between malarial infection and haemoglobin level, CD4+ counts, and ART regimen, as well as predisposing risk factors that influenced occurrence of malarial infection in the women. Thick and thin blood smears were prepared and stained with Giemsa. Haemoglobin level was determined using a hematology analyzer, while the flow cytometry was used to measure CD4+ counts. Sociodemographic and obstetrical parameters were obtained through the administration of questionnaires. Of the 159 HIV infected pregnant women examined, 33.3% (59/159) had malarial infection. Malarial infection was significantly higher in pregnant women who were divorced, 40.24% (33/82) (χ2=5.72; P=0.05), were at their first trimester (4–12 weeks), 54.8% (17/31) (χ2=14.85; P=0.01), had CD4+ = [201–500 cells/μL], 42.42% (42/99) (χ2=10.13; P=0.00), and those that had severe anaemia (<8 dg/L), 100.00% (χ2= 45.75; P=0.00). However, risk factors that influenced the occurrence of malarial infection in the pregnant women were occupation (farming) (AOR=0.226; P=0.03), marital status (divorced) (AOR=2.80; P=0.02), gestation (first trimester) (AOR=0.33; P=0.00), haemoglobin level (Hb < 8 dg/L) (AOR=0.02; P=0.00), and CD4+ counts (low CD4+) (OR=0.40; P=0.05). The study reported endemicity of malaria in HIV infected pregnant women living in rural areas of Benue State, Nigeria. Malarial infection was higher in women that were divorced, and at their first trimester, had low CD4+ count, and had severe anaemia. Farming, divorce, gestation, severe anaemia, and low CD4+ counts were predisposing risk factors that influenced malaria occurrence in the HIV infected pregnant women. It is advocated that HIV infected pregnant women should be properly and thoroughly educated on malaria preventive measures in rural areas so as to avoid unpleasant effect of malaria during their pregnancies.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Barnabas Kahiira Natamba ◽  
Arthur Araali Namara ◽  
Moffat Joha Nyirenda

Abstract Background The burden, determinants and outcomes of gestational diabetes mellitus (GDM) in sub-Saharan Africa are not known. We summarized existing evidence on the prevalence, risk factors and complications of GDM in the region. Methods PubMed was searched from inception to January 31st 2019. Studies were included if carried out in any of the sub-Saharan Africa countries and were available as abstracts or full texts. Interventional studies and those only including qualitative data were excluded. We employed random effects modelling to estimate the pooled GDM prevalence and risk ratios (RRs) for risk factors and outcomes of GDM and their 95%CI. Results 283 papers were identified in the initial search, 33 of which met the inclusion criteria. Data on GDM burden suggest a pooled prevalence of 9% (95%CI, 7–12%). Family history of type 2 diabetes and previous history of GDM, macrosomia, stillbirth and abortion were important risk factors of GDM. In addition, being overweight or obese, over 25 years of age or hypertensive increased the risk of GDM. In terms of complications, GDM more than doubles the risk macrosomia (RR; 95%CI: 2.2; 1.1–4.4). Conclusions There is a high burden of gestational diabetes mellitus in sub-Saharan Africa, but more studies are needed to document locally important risk factors as well as maternal and offspring outcomes. Interventions to reduce obesity among older African women might lead to reduced risk of GDM in sub-Saharan Africa.


Author(s):  
Dattatraya D. Bant ◽  
Shiv Kumar

Background: Anaemia in pregnancy is one of the major causes of maternal morbidity and mortality in India and world. Anaemia in pregnancy continues to be a problem in spite of national programs for its prevention and control. It accounts for 1/5th of maternal deaths worldwide and 16% in India and is the major factor responsible for low birth weight, abortions, premature birth, and post-partum haemorrhage. Hence determining the status and factors influencing anaemia among pregnant women is essential to treat and prevent the same. Objective of this study was to assess the prevalence and risk factors associated with anaemia among pregnant women.Methods: A cross sectional study was conducted among 200 pregnant women attending for antenatal care at KIMS OPD from 3rd June to 4th July. A pretested, semi-structured questionnaire was applied to collect data. Haemoglobin estimation was done by Sahli’s method.Results: Prevalence of anaemia among pregnant women was found to be 81%; majority had moderate anaemia 57%. The mean age of pregnant women in the study is 24.55 years and 46.5% belong to lower socioeconomic status, 43% lived in joint families. Factors influencing anaemia were multi-parity, short inter-pregnancy interval, no history of recent deworming and iron and folic acid tablets intake.Conclusions: In the present study, the prevalence of anaemia among pregnant women was found to be very high i.e., 81% especially among illiterates, low income groups, multiparous women, short inter-pregnancy interval, no history of recent deworming and iron and folic acid tablets intake. 


Author(s):  
Beng Kwang Ng ◽  
Mardiana Kipli ◽  
Abdul Kadir Abdul Karim ◽  
Suhaila Shohaimi ◽  
Nur Azurah Abdul Ghani ◽  
...  

AbstractBackgroundBack pain is a common presenting complaint during pregnancy and it is often being considered as part of the pregnancy process. The purpose of the study is to investigate the prevalence of back pain in pregnancy, risk factors and its impact on the quality of life in pregnant women.Materials and methodsThree hundred and fifty-eight pregnant women who attended the antenatal clinic in Universiti Kebangsaan Malaysia (UKM) Medical Centre were recruited in this cross-sectional study from October 2011 until April 2012. The back pain was further classified into lumbar pain and posterior pelvic pain. The severity of back pain was assessed using visual analoque scale (VAS) and the functional limitation was assessed using the Oswestry Disability Questionnaire (ODQ).ResultThe prevalence of back pain in pregnancy was 84.6%. Occupation and previous history of back pain were associated with back pain in pregnancy. In terms of functional limitation disability, total ODQ score was statistically significant correlate with severity of pain (VAS score). Personal care, sitting, standing, sex life and social life were significantly affected.ConclusionThe risk factors for back pain in pregnancy were type of occupation and history of back pain. The higher VAS score, the more ODQ will be affected. Personal care, sitting, standing, sex life and social life were significantly affected.


2016 ◽  
Vol 31 (3) ◽  
pp. 91-94
Author(s):  
A. B. Ganiyu ◽  
L. Mason ◽  
L. H. Mabuza

Background: The prevalence of syphilis in pregnancy varies across the globe and among different age groups within the same country. In sub-Saharan Africa, syphilis prevalence among pregnant women has been found to range from 2.5 to 18% among antenatal clinic attendees, with the highest prevalence in the age group 35–49 years. Also, it is higher in the rural than urban clinics.Objectives: To determine trends in syphilis prevalence using the Venereal Disease Research Laboratory (VDRL) and the Rapid Plasma Reagin (RPR) test among pregnant women attending the public antenatal clinics in Gaborone, Botswana (2004–2008).Study design: Cross-sectional study using routinely collected antenatal data.Results: The overall syphilis prevalence amongst pregnant women in Gaborone, Botswana decreased from 2.96% (95% CI, 2.55– 3.37) in 2004 to 1.15% (95% CI, 0.89–1.41) in 2008 (p 0.001). The age specific prevalence per total number of reactive VDRL/RPR was highest amongst pregnant women aged 26 to 30 years (p 0.001) and lowest for those aged 16 to 20 years (p 0.025) during the period 2004–2008. However, there were variations in syphilis prevalence rates within and between the clinics.Conclusion: Syphilis sero-positivity in pregnancy in Gaborone, Botswana has been declining for the last five years, but was more prevalent amongst pregnant women aged 26 to 30 years with the lowest prevalence among those aged 16 to 20 years during the period 2004 to 2008. This decline may be attributed to a number of factors and, in particular, the adoption of the syndromic approach for management of sexually transmitted infections in the country.


2015 ◽  
Vol 53 (4) ◽  
pp. 505-531 ◽  
Author(s):  
Caitriona Dowd

AbstractWhat explains the emergence of Islamist violence as a substantial security threat in such diverse contexts as Kenya, Mali and Nigeria? This article addresses this question through an exploration of the strategies of governance employed by states, and how these shape the emergence and mode of collective violence. Conflict research often emphasises the specificity of Islamist violence; but these conflicts can be understood as a form of political exclusion and grievance-based violence, comparable to other forms of political violence. Further, violent Islamist groups emerge from local conditions: the areas in which groups are established share similar local experiences of governance and political marginalisation; a history of violent conflict on which Islamist militants capitalise; and key triggering events expanding or reinforcing state exclusion. These findings challenge a narrative emphasising the global, interconnected nature of Islamist violence. This article pairs data from the Armed Conflict Location & Event Dataset (ACLED) with Afrobarometer survey data and case study evidence to identify drivers of Islamist violence across three African countries.


2021 ◽  
Vol 36 (1) ◽  
Author(s):  
Bongekile Ngobese ◽  
Nathlee S. Abbai

Background: Sexually transmitted infections (STIs) are a major health problem in most countries of the world, particularly in developing countries where the resources and technology to diagnose and treat them are limited. Currently, there is limited data on STIs and risk factors for these infections in pregnant women living with human immunodeficiency virus (HIV), especially in sub-Saharan Africa (SSA). This review provides data on the prevalence and risk factors for STIs in pregnant women living with HIV from SSA. This review also describes the association between STIs and HIV on pregnancy and birth outcomes as well as highlights the importance of laboratory-based diagnosis of STIs.Method: An electronic search of online databases was used to find and collect relevant research articles connected to the prevalence, adverse pregnancy and birth outcomes, health complications and risk factors associated with STIs and HIV in pregnant women from SSA. The search was limited to articles published in English. Relevant studies were identified by searching literature from January 2001 to date. The search yielded 4709 results.Results: In SSA, STIs are highly prevalent in pregnant women and are widely known to be linked with an increased risk of poor maternal and neonatal outcomes. These infections are often asymptomatic and highly prevalent in pregnant women. The screening of STIs in pregnant women living with HIV can reduce the risk of mother-to-child transmission (MTCT) and screening and treatment for STIs can also prevent adverse perinatal outcomes. It is important to recognise regional and national STI epidemics in order to promote STI prevention and control interventions considering the test and treat approach as opposed to syndromic management.Conclusion: This review highlights the need to use diagnostic screening methods instead of syndromic STI management in SSA. Moreover, more research into effective prevention and treatment measures for STIs in pregnant women is urgently required.


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