scholarly journals Impact of Preterm Birth and Post-Discharge Growth on Cardiometabolic Outcomes at School Age: A Case Control Study

2020 ◽  
Author(s):  
Jungha Yun ◽  
Young Hwa Jung ◽  
Seung Han Shin ◽  
In Gyu Song ◽  
Young Ah Lee ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Fat Mass ◽  
Case Control Study ◽  
Fasting Glucose ◽  
Case Control ◽  
School Age ◽  
Z Score ◽  
School Aged Children ◽  
Early School ◽  
Control Study

Abstract Background: Adverse metabolic outcomes later in life have been reported among children or young adults who were born small for gestational age. This study was conducted to examine the impact of preterm birth and subsequent growth after hospital discharge on cardiometabolic risks among early school-aged children. Methods: This case-control study included school-aged children born prematurely (n = 60) and at term (n = 110). Body size, fat mass, blood pressure (BP), glucose, insulin, leptin, adiponectin, and lipid profiles were measured. Weight z-score changes between discharge and early school-age period were also calculated, and factors associated with BP and insulin resistance were analyzed.Results: Early school-aged children who were born preterm had lower fat masses, higher systolic BP and diastolic BP, and higher values of fasting glucose, insulin, and homeostatic model assessment of insulin resistance (HOMA-IR), compared to children born at term. Preterm birth was correlated with HOMA-IR and BPs after adjusting for various factors, including fat mass index and weight z-score changes. Weight z-score changes were associated with HOMA-IR, but not with BPs. Conclusions: Although early school-aged children born prematurely showed lower weight and fat mass, they had higher BPs, fasting glucose, HOMA-IR, and leptin levels. The associations of preterm birth with cardiometabolic factors were independent of weight, fat mass and weight gain velocity.

Dietary Choline Intake during Pregnancy and PEMT rs7946 Polymorphism on Risk of Preterm Birth: A Case-Control Study

2021 ◽  
pp. 1-10
Author(s):  
Jie Zhu ◽  
Yu-Hong Liu ◽  
Xiang-Long He ◽  
Martin Kohlmeier ◽  
Li-Li Zhou ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Case Control Study ◽  
Chinese Women ◽  
Case Control ◽  
Han Chinese ◽  
Food Frequency ◽  
Term Delivery ◽  
Choline Intake ◽  
Dietary Choline ◽  
Control Study

<b><i>Introduction and Aims:</i></b> Choline-metabolizing genetic variation may interact with choline intake on fetal programming and pregnancy outcome. This case-control study aims to explore the association of maternal choline consumption and phosphatidylethanolamine N-methyltransferase (PEMT) gene polymorphism rs7946 with preterm birth risk. <b><i>Methods:</i></b> 145 Han Chinese women with preterm delivery and 157 Han Chinese women with term delivery were recruited in Shanghai. Dietary choline intake during pregnancy was assessed using a validated food frequency questionnaire. Additionally, DNA samples were genotyped for PEMT rs7946 (G5465A) with plasma homocysteine (Hcy) levels measured. <b><i>Results:</i></b> Compared with the lowest quartile of choline intake, women within the highest consumption quartile had adjusted odds ratio (aOR) for preterm birth of 0.48 (95% confidence interval, CI [0.24, 0.95]). There was a significant interaction between maternal choline intake and PEMT rs7946 (<i>p</i> for interaction = 0.04), where the AA genotype carriers who consumed the energy-adjusted choline &#x3c;255.01 mg/day had aOR for preterm birth of 3.75 (95% CI [1.24, 11.35]), compared to those with GG genotype and choline intake &#x3e;255.01 mg/day during pregnancy. Additionally, the greatest elevated plasma Hcy was found in the cases with AA genotype and choline consumption &#x3c;255.01 mg/day (<i>p</i> &#x3c; 0.001). <b><i>Conclusion:</i></b> The AA genotype of PEMT rs7946 may be associated with increased preterm birth in these Han Chinese women with low choline intake during pregnancy.

scholarly journals Maternal Dietary Nutrient Intake and Its Association  with Preterm Birth: A Case‐control Study in Beijing,  China

Nutrients ◽  
2017 ◽  
Vol 9 (3) ◽  
pp. 221 ◽  
Author(s):  
Yan Zhang ◽  
Hong Zhou ◽  
Anthony Perkins ◽  
Yan Wang ◽  
Jing Sun
Keyword(s):  
Preterm Birth ◽  
Nutrient Intake ◽  
Case Control Study ◽  
Case Control ◽  
Dietary Nutrient ◽  
Beijing China ◽  
Control Study

Cognition, academic achievement, and epilepsy in school-age children: A case–control study in a developing country

2014 ◽  
Vol 33 ◽  
pp. 39-44 ◽  
Author(s):  
R. Melbourne Chambers ◽  
N. Morrison-Levy ◽  
S. Chang ◽  
J. Tapper ◽  
S. Walker ◽  
...  
Keyword(s):  
Academic Achievement ◽  
Developing Country ◽  
Case Control Study ◽  
Case Control ◽  
School Age Children ◽  
School Age ◽  
Control Study

Employment in Nursing and Preterm Birth: Are They Linked?

PEDIATRICS ◽  
1996 ◽  
Vol 98 (6) ◽  
pp. 1197-1198
Author(s):  
JUDITH LUMLEY
Keyword(s):  
Preterm Birth ◽  
Working Conditions ◽  
Case Control Study ◽  
Case Control ◽  
Cross Sectional ◽  
Neonatal Nurses ◽  
Fetal Health ◽  
Mailed Survey ◽  
Control Study ◽  
Specialist Group

The possibility that employment itself, with all its rewards, both intrinsic and monetary, could be harmful to maternal and fetal health is always a matter for concern. When that suggestion is made about an archetypical female form of employment (nursing), and a specialist group devoted to the health care of women and infants, it is deeply alarming. So the recent publication which states, "our results show that strenuous working conditions are an important risk factor for preterm birth among US nurses," has been widely reported and discussed. The study was a case-control study with cases and controls drawn from respondents to a cross-sectional mailed survey of members of the Association of Women's Health, Obstetric and Neonatal Nurses.

scholarly journals Regulatory Cytokine Expression and Preterm Birth: Case-Control Study Nested in a Cohort

PLoS ONE ◽  
2016 ◽  
Vol 11 (8) ◽  
pp. e0158380 ◽  
Author(s):  
Thaís Basso de Brito Pereira ◽  
Erika Barbara Abreu Fonseca Thomaz ◽  
Flávia Raquel Fernandes do Nascimento ◽  
Ana Paula Silva de Azevedo dos Santos ◽  
Rosângela Lucena Fernandes Batista ◽  
...  
Keyword(s):  
Preterm Birth ◽  
Case Control Study ◽  
Case Control ◽  
Cytokine Expression ◽  
Regulatory Cytokine ◽  
Control Study

scholarly journals Determinants of preterm birth in public hospitals in central Ethiopia: an unmatched case-control study

F1000Research ◽  
2021 ◽  
Vol 10 ◽  
pp. 773
Author(s):  
Berhanu Senbeta Deriba ◽  
Agumas Fentahun Ayalew ◽  
Addis Adera Gebru
Keyword(s):  
Preterm Birth ◽  
Cigarette Smoking ◽  
Birth Outcomes ◽  
Case Control Study ◽  
Case Control ◽  
Public Hospitals ◽  
Medical Illness ◽  
Adverse Birth Outcomes ◽  
Central Ethiopia ◽  
Control Study

Background: Around 15 million babies are born prematurely in the world every year. The most common cause of neonatal death in Ethiopia is premature birth. To reduce the rate of preterm delivery by correcting modifiable or preventable causes, the availability of local data is important. Hence, this study aimed to identify the determinants of preterm birth among women who gave birth in public hospitals in central Ethiopia. Methods: An Institutional-based unmatched case-control study was conducted at public hospitals in central Ethiopia to select 170 cases and 340 controls. The collected data were entered into EPI INFO and transferred to SPSS for analysis. Tables, graphs, and proportions were used to present the results. Binary and multiple logistic regressions analysis were computed to identify determinants of preterm birth. Adjusted Odds Ratio (AOR), 95% Confidence Interval (CI), and a p-value < 0.05 were computed to determine the presence of an association between preterm birth and independent variables. Results: A total of 166 cases and 332 controls participated in the study, giving a response rate of 97.6%. Cigarette smoking (AOR=3.77, 95% CI=1.35,10.56), alcohol consumption (AOR=1.85, 95% CI=1.11,3.10), wanted but unplanned pregnancy (AOR=3,95% CI=1.68,5.34), neither wanted nor planned pregnancy(AOR=3.61% CI=1.62,8.06), lack of antenatal care (ANC) visits (AOR=4.13, 95% CI=1.95, 8.74), adverse birth outcomes (AOR=5.66, 95% CI=2.88,11.12), presence of a diagnosed illness (AOR=2.81, 95% CI=1.37, 5.76), presence of one or more of obstetrics complications(AOR=6.44, 95% CI=5.49, 3.35, 9), and hemoglobin level < 11g/dl  (AOR=2.78, 95% CI=1.48, 5.22) were determinants of preterm birth. Conclusion:-In this study, cigarette smoking status, alcohol drinking status, pregnancy status, adverse birth outcomes, ANC visits, obstetric complications,  presence of medical illness, and anemia were identified as determinants of preterm birth. It is important to encourage such women to attend ANC visits, stop smoking, and abstain from alcohol.

scholarly journals Risk Factors for Cerebral Palsy in Brazilian Children: A Case-Control Study

2020 ◽  
Author(s):  
Marcus Valerius da Silva Peixoto ◽  
Andrezza Marques Duque ◽  
Allan Dantas dos Santos ◽  
Shirley Verônica Melo Almeida Lima ◽  
Caíque Jordan Nunes Ribeiro ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cerebral Palsy ◽  
Birth Weight ◽  
Preterm Birth ◽  
Case Control Study ◽  
Case Control ◽  
Perinatal Factors ◽  
Apgar Scores ◽  
Control Study ◽  
Brazilian Children

ABSTRACTBackgroundCerebral palsy is the main cause of physical disability in childhood.ObjectivesThis study analyzed prenatal and perinatal risk factors that contribute to cerebral palsy in Brazilian children.MethodsA case-control study was conducted with 2- to 10-year-old children in the city of Aracaju, Sergipe, Brazil. The cases were population-based, selected from the Primary Health Care services. The controls were selected from the database of the Brazilian Live Births Information System. Controls were paired with cases by gender, year, and hospital of birth.ResultsA total of 570 participants (114 cases and 456 controls) were studied. Most of the participants were male, with bilateral spastic cerebral palsy. Among the prenatal factors examined, the presence of congenital anomalies was significantly different between cases and controls (OR = 54.28, [95% CI 12.55, 234.86]). The analysis of perinatal factors revealed significant differences between cases and controls in low birth weight (OR = 3.8, [95% CI 2.34, 6.16]), preterm birth (OR = 2.31, [95% CI 1.41, 3.80]), and low Apgar scores (OR = 14.73, [95% CI 5.27, 41.15]).ConclusionsThe main prenatal and perinatal factors associated with cerebral palsy in our population were congenital anomalies, low Apgar scores, low birth weight, and preterm birth. The perinatal period had more risk factors, demanding a deeper study of their causes and of possible preventive measures.

scholarly journals Determinants of soil-transmitted helminth infections among pre-school-aged children in Gamo Gofa zone, Southern Ethiopia: A case-control study

PLoS ONE ◽  
2020 ◽  
Vol 15 (12) ◽  
pp. e0243836
Author(s):  
Mekuria Asnakew Asfaw ◽  
Teklu Wegayehu ◽  
Tigist Gezmu ◽  
Alemayehu Bekele ◽  
Zeleke Hailemariam ◽  
...  
Keyword(s):  
Rural Areas ◽  
Urban Areas ◽  
Case Control Study ◽  
Water Source ◽  
Case Control ◽  
Southern Ethiopia ◽  
School Aged Children ◽  
Context Specific ◽  
Gamo Gofa ◽  
Control Study

Background Pre-school aged children (PSAC) are highly affected by soil-transmitted helminths (STH), particularly in areas where water, sanitation, and hygiene (WASH) are inadequate. Context-specific evidence on determinants of STH infections in PSAC has not been well established in the study area. This study, therefore, aimed to fill these gaps in Gamo Gofa zone, Southern Ethiopia. Methods A community-based unmatched case-control study, nested in a cross-sectional survey, was conducted in January 2019. Cases and controls were identified based on any STH infection status using the Kato-Katz technique in stool sample examination. Data on social, demographic, economic, behavioral, and WASH related variables were collected from primary caregivers of children using pre-tested questionnaire. Determinants of STH infections were identified using multivariable logistic regression model using SPSS version 25. Results A total of 1206 PSAC (402 cases and 804 controls) participated in this study. Our study showed that the odds of STH infection were lowest among PSAC living in urban areas (AOR = 0.55, 95% CI: 0.39–0.79), among those from households with safe water source (AOR = 0.67, 95% CI: 0.47–0.0.93), and in those PSAC from households with shorter distance from water source (<30 minutes) (AOR = 0.51, 95% CI: 0.39–0.67). On the other hand, the odds of STH infection were highest among PSAC from households that had no functional hand washing facility (AOR = 1.36, 95% CI: 1.04–1.77), in those PSAC from households that had unclean latrine (AOR: 1.82, 95% CI: 1.19–2.78), and among those PSAC under caregivers who had lower score (≤5) on knowledge related to STH transmission (AOR = 1.85, 95% CI: 1.13–3.01). Conclusions Given efforts required eliminating STH by 2030; the existing preventive chemotherapy intervention should be substantially strengthened with WASH and behavioral interventions. Thus, an urgent call for action is required to integrate context-specific interventions, particularly in rural areas.

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