Optical Biometry and Influence of Media Opacity Due to Cataract on Development of Axial Length in Pediatric Eyes
Abstract Aim: To study the influence of media opacity due to cataract on the development of axial length in paediatric eyes with the help of optical biometry.Method: In this prospective, observational study, all patients attending the paediatric outpatient department (OPD) of the institute underwent a comprehensive ocular and systemic evaluation. Patients suffering from any other ocular disease and systemic disease were excluded. Optical biometry was performed to measure the axial length in all the eyes. In each eye, five biometric measurements were acquired and average of these five readings were considered for the study. Patients were divided into three groups after proper age matching – 1. Group A (Bilateral cataract) 2. Group B (Unilateral cataract) 3. Group C (Bilateral normal). The axial length of the various groups were then compared. Results: A total of 540 eyes of 270 patients were involved in the study. 120 cases (n = 240 eyes) in Group A (bilateral cataract), 30 cases (n = 60 eyes) in Group B (unilateral cataract) and 120 (n = 240 eyes) in Group C (no cataracts). The mean age of the patients in all the groups was 9.38 ± 3.67 years (range: 1-17 years). In Group B, the difference in the AL between the cataractous eyes (22.44±1.48 mm; n = 30) and the fellow eyes (22.09±0.93 mm; n = 30) was not statistically significant (P = 0.277). The difference in the AL between the cataractous right eyes of Group A (22.9±3.51 mm, n = 120) and the non-cataractous right eye of Group C fellow eyes (22.57±0.71 mm, n = 120) was not statistically significant (P = 0.316). The difference in the AL between the cataractous left eyes of Group A (23.06±2.33 mm, n = 120) and the non-cataractous left eyes of Group C fellow eyes (22.56±0.78, n = 120) was statistically significant (P = 0.028). Conclusion: The results of our study and reported literature to date, seem to indicate a more significant role of genetic factors in comparison to media opacity, in the proportionate development of the AL.