scholarly journals Evaluation of Antimicrobial, Cytotoxicity and Catalytic Activities of CuO-NPs Synthesized by Tanacetum Parthenium Extract

2021 ◽  
Author(s):  
Mojtaba Ranjbar ◽  
Mahsa Dastani ◽  
Fatemeh Khakdan
Keyword(s):  
Organic Dyes ◽  
Medical Sciences ◽  
Cytotoxic Effects ◽  
Suitable Candidate ◽  
Catalytic Activities ◽  
Cuo Nps ◽  
Tanacetum Parthenium ◽  
Microbial Infections ◽  
Mean Size ◽  
Degradation Activity

Abstract Development of efficient methods for treating microbial infections, cancer, and toxic organic dyes is a serious challenge in medical sciences. The purpose of this study is to synthesize CuO-NPs using T. parthenium extract and to evaluate its anticancer, antimicrobial, and catalytic activity. CuO-NPs were characterized by UV-Vis, XRD, FTIR, FESEM, and EDX. UV-Vis spectra exhibited surface plasmonic resonance at 298 nm of synthesized CuO-NPs. The synthesized CuO-NPs were pure, predominantly spherical with mean size of 16 nm. FTIR confirmed that CuO-NPs were reducted and stabilized with the biomolecules present in the T. parthenium extract. CuO-NPs indicated excellent degradation activity for the industrial dyes, i.e., MO (96.6% removal in 400s), Rh B (98.3% removal in 400s), MB (98.7% removal in 400s) and CR (99.6% removal in 180s). CuO-NPs showed excellent inhibition against selected microorganisms, especially E.coli and C. albicans. CuO-NPs have also shown good anticancer activity against A549, Hela, and MCF7 cancer cell lines (IC50 = 65.0, 57.4, and 71.8 µg/mL, respectively) while negligible cytotoxic effects were observed on L929 (IC50 = 226.1 µg/mL). The results proposed that synthesized CuO-NPs can be considered as a suitable candidate for biomedical, pharmaceutical, and environmental applications.

Sonocatalytic degradation of organic dyes and comparison of catalytic activities of CeO2/TiO2, SnO2/TiO2 and ZrO2/TiO2 composites under ultrasonic irradiation

2010 ◽  
Vol 17 (4) ◽  
pp. 642-648 ◽  
Author(s):  
Jun Wang ◽  
Yanhui Lv ◽  
Liqun Zhang ◽  
Bin Liu ◽  
Renzheng Jiang ◽  
...  
Keyword(s):  
Ultrasonic Irradiation ◽  
Organic Dyes ◽  
Catalytic Activities

Multifunctional magnetic oleic acid-coated MnFe2O4/polystyrene Janus particles for water treatment

2016 ◽  
Vol 4 (30) ◽  
pp. 11768-11774 ◽  
Author(s):  
Deng Pan ◽  
Fangzhi Mou ◽  
Xiaofeng Li ◽  
Zhuoyi Deng ◽  
Jing Sun ◽  
...  
Keyword(s):  
Oleic Acid ◽  
Water Treatment ◽  
Organic Dyes ◽  
Janus Particles ◽  
Catalytic Activities

Multifunctional MnFe2O4@OA/PS Janus particles (JPs) for water treatment are demonstrated in this work. They can not only encapsulate and separate oil from water, but also degrade organic dyes in water due to their amphiphilic properties, magnetic responses and high catalytic activities.

scholarly journals Biosynthesis of copper(II) oxide nanoparticles using Murayya koeniggi aqueous leaf extract and its catalytic activity in 4-nitrophenol reduction

2019 ◽  
Vol 15 (2) ◽  
pp. 218-224 ◽  
Author(s):  
Mustaffa Shamsuddin ◽  
Nurulhuda Raja Nordin
Keyword(s):  
Leaf Extract ◽  
Low Cost ◽  
Precious Metals ◽  
Spherical Shape ◽  
Xrd Analysis ◽  
Oxide Nanoparticles ◽  
Catalytic Activities ◽  
Cuo Nps ◽  
Nitrophenol Reduction ◽  
Wide Range

Copper(II) oxide nanoparticles (CuO NPs) has a wide range of applications as catalysts. The natural abundance of copper and its relatively low cost make it a viable alternative to catalysts made from expensive precious metals such as platinum and palladium. In this study, a rapid, simple and green method was developed for the synthesis of CuO NPs using an aqueous extract of Murayya koenigii leaves. Several parameters were optimized, namely, the volume of leaf extract, pH, reaction temperature and reaction time. The optimum condition for the biosynthesis was obtained by using 3 mL of leaf extract; 10 mL of 5 mM CuSO, at pH 11, at room temperature.  The biosynthesis was completed within 50 minutes. The synthesized CuO NPs were characterized using Ultraviolet-visible Spectroscopy (UV-Vis), Fourier Transform Infrared Spectroscopy (FTIR), X-ray Diffraction (XRD), and Transmission Electron Microscope (TEM) analyses. The UV-Vis absorption spectra confirmed the formation of CuO NPs with characteristic peak at 634 nm. The FTIR spectroscopic analysis of the biosynthesized CuO NPs confirmed the surface adsorption of the bioactive components in the leaf extract that acted as the reducing agent and stabilizing agent for the metal nanoparticles. XRD analysis showed a series of diffraction peaks at 2θ of 32.5°, 35.5°, 38.6°, 48.8°, 53.4°, 58.1°, 61.5°, 66.3°, 68.0°, 72.4° and 75.0°, corresponding to (110), (002), (111), (202), (020), (202), (113), (311), (220), (311) and (222) respectively. From TEM images, CuO NPs were of spherical shape with a mean diameter of 8.4 nm. The biosynthesized CuO NPs demonstrated good catalytic activities on the reduction 4-nitrophenol (4-NP) to 4-aminophenol (4-AP) in the presence of sodium borohydride, NaBH4 and can be reused three times without significant decrease in the catalytic activities

scholarly journals Porous metalloporphyrinic nanospheres constructed from metal 5,10,15,20-tetraksi(4′-ethynylphenyl)porphyrin for efficient catalytic degradation of organic dyes

RSC Advances ◽  
2018 ◽  
Vol 8 (14) ◽  
pp. 7330-7339 ◽  
Author(s):  
Yongjin Li ◽  
Liming Wang ◽  
Yong Gao ◽  
Weijun Yang ◽  
Yingying Li ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Organic Dyes ◽  
Coupling Reaction ◽  
Catalytic Degradation ◽  
Sonogashira Coupling ◽  
Catalytic Activities ◽  
Sonogashira Coupling Reaction

A kind of novel conjugated metalloporphyrin polymers were synthesized by the Sonogashira coupling reaction. They were microporous nanospherical polymers and showed excellent catalytic activities and reusability in degradation of methylene blue.

scholarly journals Transition metal ion-doped In2O3 nanocubes: investigation of their photocatalytic degradation activity under sunlight

2021 ◽  
Author(s):  
Velayutham Shanmuganathan ◽  
Jayaraj Santhosh Kumar ◽  
Raman Pachaiappan ◽  
Paramasivam Thangadurai
Keyword(s):  
Photocatalytic Activity ◽  
Transition Metal ◽  
Photocatalytic Degradation ◽  
Indium Oxide ◽  
Metal Ion ◽  
Organic Dyes ◽  
Transition Metal Ion ◽  
Ion Doping ◽  
Degradation Activity

The objective of this work was to study the effect of transition metal ion doping (1 wt% of Mn, Fe, Co, Ni, and Cu) in indium oxide (In2O3) on its photocatalytic activity to degrade organic dyes, which are considered potential environment pollutants.

Single-wall carbon nanotubes modified with organic dyes: Synthesis, characterization and potential cytotoxic effects

2010 ◽  
Vol 211 (2-3) ◽  
pp. 99-107 ◽  
Author(s):  
Gustavo M. do Nascimento ◽  
Rafael C. de Oliveira ◽  
Noriberto A. Pradie ◽  
Paulo R. Gessolo Lins ◽  
Paulo R. Worfel ◽  
...  
Keyword(s):  
Carbon Nanotubes ◽  
Organic Dyes ◽  
Single Wall Carbon Nanotubes ◽  
Cytotoxic Effects ◽  
Single Wall Carbon

scholarly journals Chitosan-based silver nanoparticles: A study of the antibacterial, antileishmanial and cytotoxic effects

2016 ◽  
Vol 32 (4) ◽  
pp. 397-410 ◽  
Author(s):  
Douglas dos Santos Lima ◽  
Beatriz Gullon ◽  
Alejandra Cardelle-Cobas ◽  
Lucas M Brito ◽  
Klinger AF Rodrigues ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Bacterial Strains ◽  
Cytotoxic Effects ◽  
Promising Alternative ◽  
Force Microscopy ◽  
Atomic Force ◽  
Transmission Electron ◽  
Antibacterial Assay ◽  
Microbial Infections ◽  
Marked Activity

Silver nanoparticles have been studied as an alternative for treatment of microbial infections and leishmaniasis, without promoting induction of microbial or parasite resistance. In this study, chitosan-based silver nanoparticles were synthesized from silver nitrate (AgNO3), sodium borohydride as a reducing agent, and the biopolymer chitosan as a capping agent. The chitosan-based silver nanoparticles were characterized by ultraviolet–visible, Fourier transform infrared, dynamic light scattering, zeta potential, atomic force microscopy, and transmission electron microscope. The antibacterial assay was performed by determination of the minimum inhibitory concentration. The antileishmanial and the cytotoxic effects induced by AgNO3, chitosan, and chitosan-based silver nanoparticles were analyzed by resazurin and MTT colorimetric assays, respectively. AgNO3, chitosan, and chitosan-based silver nanoparticles induced a marked activity against all bacterial strains and promastigote forms of Leishmania amazonensis at minimum inhibitory concentrations ranging from 1.69 to 3.38 µg Ag/mL. Interestingly, the chitosan-based silver nanoparticles presented less cytotoxicity than the AgNO3 alone and were more active against L. amazonensis than solely chitosan. Furthermore, the cytotoxic concentrations (CC50) of both chitosan and chitosan-based silver nanoparticles against macrophages were significantly higher than the IC50 against promastigotes. Thus, the chitosan-based silver nanoparticles represent a promising alternative for the treatment of microbial infections and leishmaniasis.

scholarly journals Cytotoxic Effects of Combined Walnut Shell-Extracted Copper Oxide: Nanoparticles and Hydroalcoholic Extracts of Aloe vera Against Human Leukemic Cell Line

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Seyyed Meysam Abtahi Froushani ◽  
Asghar Zamani ◽  
Ardeshir Abbasi
Keyword(s):  
Copper Oxide ◽  
Cell Line ◽  
K562 Cell ◽  
Aloe Vera ◽  
K562 Cells ◽  
Copper Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Cytotoxic Effects ◽  
Cuo Nps ◽  
Ic50 Value

Background: Anticancer effects of Aloe vera and copper oxide nanoparticles (CuO NPs) have been separately determined. Hence, we investigated whether combining the hydroalcoholic extract of Aloe vera and green CuO NPs produced by eco-friendly and walnut shells could provide synergistic cytotoxicity against K562 cell lines. Methods: The K562 cells and PBMCs (1 × 105 cells/100 μL/well) were treated with serial dilution of Aloe vera extract (0, 20, 40, 60, 80, 160 and 320 mg/ mL) and green CuO NPs (0, 50, 100, 200 and 400 μM). After incubation for 24h, the viability of cells was determined by MTT assay. Cells were exposed to a mixture of Aloe vera extract and Green CuO NPs at the half-maximal inhibitory concentration (IC50) to assess the inhibitory effects. Results: The extract of Aloe vera and green CuO NPs had cytotoxic effects against K562 (cell-line in a dose-dependent manner). Unlike Aloe vera, the marginal safety of green CuO NPs was low. There were no significant dissimilarities in the IC50 value of the green CuO NPs against K562 cells compared to the IC50 value of the Green CuO NPs against PBMCs (175 ± 9 μM vs. 186.89 ± 8.88 μM). Combined treatment with minimal cytotoxic doses provided synergistic benefits and caused more cytotoxicity in K562 cells toward their separated treatment. Meanwhile, this combined concentration enhanced the cell-survival, not the cytotoxicity in PBMC treated cells. Conclusions: The combinative concentration of Aloe vera and green CuO may be considered alternative medicine later.

scholarly journals LC-MS Characterization and Biological Activities of Cuban Cultivars of Plectranthus neochilus Schltr

Plants ◽  
2022 ◽  
Vol 11 (1) ◽  
pp. 134
Author(s):  
Annarli O. Rodríguez-Ferreiro ◽  
Ania Ochoa-Pacheco ◽  
Daniel Méndez-Rodriguez ◽  
Emilia Ortiz-Beatón ◽  
Oneida Font-Salmo ◽  
...  
Keyword(s):  
Antimicrobial Activity ◽  
Biological Activities ◽  
Glandular Trichomes ◽  
Major Constituent ◽  
Cytotoxic Effects ◽  
Viability Assay ◽  
Microbial Infections ◽  
Abietane Diterpenes ◽  
High Level ◽  
First Time

Plectranthus neochilus Schltr. (Lamiaceae) is a plant recently introduced in Cuba. Worldwide, it is an ethnomedicinal alternative for its use against microbial infections, but the Cuban population use the extracts to treat sleep disorders. To address this apparent incongruity, four collections (from different seasonal conditions in the year) of Cuban P. neochilus cultivars were analyzed in terms of their pharmacognostic characteristics. Three extracts using fresh and dried leaves were chemically and biologically characterized. UPLC-DAD-MS/MS analysis was performed to determine their chemical composition, while a panel of nine microorganisms was used to evaluate their antimicrobial activity. Finally, cytotoxic effects of different fractions were measured in three cell lines by the resazurin viability assay. In contrast to previously reported micro and macromorphological properties of P. neochilus, the leaves from the Cuban cultivars did not present glandular trichomes, nor did they produce quantifiable levels of essential oils. Moreover, aqueous extracts used by the population revealed no significant antimicrobial activity and were not cytotoxic. The three extracts showed a similar phytochemical composition, i.e., eight flavonoids, seven abietane diterpenes, and rosmarinic acid as the major constituent, most of them reported for the first time in this species. The low yield of essential oil, the absence of glandular trichomes, compounds with a high level of oxidation, and a moderate antimicrobial activity detected were the most distinctive pharmacognostic and biological characteristics of P. neochilus grown in Cuba. These aspects could explain its non-use as an antimicrobial.

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