scholarly journals A comparison between body mass index and waist circumference for identifying continuous metabolic syndrome risk score components in school-aged children using a structural equation modeling approach: the CASPIAN-V study

2020 ◽  
Author(s):  
Hanieh-Sadat Ejtahed ◽  
Zohre Mahmoodi ◽  
mostafa qorbani ◽  
Pooneh Angoorani ◽  
Mohammad Esmaeil Motlagh ◽  
...  

Abstract Background The purpose of this study was to investigate the association of anthropometric measures with continuous metabolic syndrome (cMetS) risk score components in a large population-based sample of children and adolescents using a path analysis. Methods This multi-centric study was performed on 3843 students aged 7-18 years who were selected by multistage, stratified cluster sampling method from 30 provinces of Iran. Demographic, anthropometric and biochemical factors were obtained and standardized residuals ( z -scores) were calculated for MetS components. A structural equation modeling approach was applied to evaluate the relationships among the study variables and to implement the subsequent structural modeling. Results The mean age of participants (52.3% boys) was 12.4±3.05 years. Standardized scores of body mass index (ZBMI) and waist circumference (ZWC) had a direct effect on standardized scores of mean arterial pressure (ZMAP) (0.23 and 0.24 in boys and 0.22 and 0.23 in girls; respectively) and triglyceride (ZTG) (0.07 and 0.04 in boys and 0.02 and 0.06 in girls; respectively), but the effect of ZWC was stronger than ZBMI on these variables. Age, socioeconomic status and sedentary behaviors showed a positive direct effect on ZWC (0.01, 0.05 and 0.07 in boys and 0.05, 0.08 and 0.002 in girls; respectively). These variables induced indirect effects on cMets risk score components through ZWC. Conclusions The magnitude of association between WC and continuous metabolic syndrome risk score components was higher compared with BMI in school-aged children, emphasizing on paying more attention to central obesity in childhood.

2010 ◽  
Vol 63 (9-10) ◽  
pp. 611-615 ◽  
Author(s):  
Branka Koprivica ◽  
Teodora Beljic-Zivkovic ◽  
Tatjana Ille

Introduction. Insulin resistance is a well-known leading factor in the development of metabolic syndrome. The aim of this study was to evaluate metabolic effects of metformin added to sulfonylurea in unsuccessfully treated type 2 diabetic patients with metabolic syndrome. Material and methods. A group of thirty subjects, with type 2 diabetes, secondary sulfonylurea failure and metabolic syndrome were administered the combined therapy of sulfonylurea plus metformin for six months. Metformin 2000 mg/d was added to previously used sulfonylurea agent in maximum daily dose. Antihypertensive and hypolipemic therapy was not changed. The following parameters were assessed at the beginning and after six months of therapy: glycemic control, body mass index, waist circumference, blood pressure, triglycerides, total cholesterol and its fractions, homeostatic models for evaluation of insulin resistance and secretion (HOMA R, HOMA B) and C- peptide. Results. Glycemic control was significantly improved after six months of the combined therapy: (fasting 7.89 vs. 10.61 mmol/l. p<0.01; postprandial 11.12 vs. 12.61 mmol/l. p<0.01, p<0.01; glycosylated hemoglobin 6.81 vs. 8.83%. p<0.01). the body mass index and waist circumference were significantly lower (26.7 vs. 27.8 kg/m2, p<0.01 and 99.7 vs. 101.4 cm for men, p<0.01; 87.2 vs. 88.5 for women, p<0.01). Fasting plasma triglycerides decreased from 3.37 to 2.45 mmol/l (p<0.001) and HOMA R from 7.04 to 5.23 (p<0.001). No treatment effects were observed on blood pressure, cholesterol, and residual insulin secretion. Conclusion. Administration of metformin in type 2 diabetes with metabolic syndrome decreased cardiovascular risk factors by reducing glycemia, triglycerides, BMI, central obesity and insulin resistance.


2020 ◽  
Vol 3 (4) ◽  
pp. 1017
Author(s):  
James Salim ◽  
Leksmono Suryo Putranto

Transportation is an activity which moving a person or an object from one place to another place. Transportation is done not for desire, it is a derived demand for humans to do the activities for fulfiling their daily needs. Shopping is one of the activities that comply their daily needs. Nowdays, online shopping is a trend. Besides easy to do, online shopping can be done any where and any time because of its online system. Along with the growth of online shopping, a lot of people prefer online shopping rather than traditional shopping to shops, markets, shopping centers and other places. Thisthings could change number of people on doing shopping trips. Thisresearch aimsto find out what factors effects someone’s decision to shop online and find out wether online shopping has a direct effect on shopping trips done by people. Data for this reseach collected by quistionnaire. This research will be done with Structural Equation Modeling (SEM) Method. This research shows that experience and trust are strong factors on someone for making decision to shop online and shows that online shopping did not effect directly to people’s shopping trips.ABSTRAKTransportasi adalah kegiatan perpindahan tempat orang atau suatu benda dari satu tempat ke tempat lainnya. Transportasi dilakukan bukan karena keinginan, melainkan sebuah kebutuhan turunan karena manusia harus melakukan aktivitas untuk memenuhi kebutuhan mereka sehari-hari. Belanja adalah salah satu kegiatan yang dilakukan untuk memenuhi kebutuhan sehari-hari. Belanja online sendiri menjadi sangat trend saat ini. Belanja online selain mudah untuk dilakukan, bisa dilakukan kapan saja, dimana saja karena sistemnya yang bersifat online. Seiring dengan perkembangan belanja online, tidak sedikit orang yang lebih memilih melakukan belanja online dibandingkan melakukan belanja langsung ke toko, pasar, pusat perbelanjaan, dan tempat lainnya. Hal ini bisa jadi mempengaruhi jumlah orang yang melakukan perjalanan belanja. Penelitian ini dilakukan mengetahui faktor apa saja yang berperan dalam keputusan seseorang melakukan belanja online dan mengetahui apakah belanja online berpengaruh secara langsung terhadap perjalanan belanja yang dilakukan masyarakat. Data untuk penelitian didapatkan melalui kuesioner. Penelitian ini akan menggunakan Metode Structural Equation Modeling atau SEM. Dari hasil penelitian didapatkan bahwa pengalaman dan kepercayaan adalah dua faktor yang kuat dalam penentuan keputusan seseorang melakukan belanja online dan belanja online tidak mempengaruhi perjalanan belanja secara langsung


2021 ◽  
Vol 2021 (1) ◽  
Author(s):  
Lauren Kupis ◽  
Zachary T. Goodman ◽  
Salome Kornfeld ◽  
Celia Romero ◽  
Bryce Dirks ◽  
...  

Obesity is associated with negative physical and mental health outcomes. Being overweight/obese is also associated with executive functioning impairments and structural changes in the brain. However, the impact of body mass index (BMI) on the relationship between brain dynamics and executive function (EF) is unknown. The goal of the study was to assess the modulatory effects of BMI on brain dynamics and EF. A large sample of publicly available neuroimaging and neuropsychological assessment data collected from 253 adults (18–45 years; mean BMI 26.95 kg/m2 ± 5.90 SD) from the Nathan Kline Institute (NKI) were included (http://fcon_1000.projects.nitrc.org/indi/enhanced/). Participants underwent resting-state functional MRI and completed the Delis-Kaplan Executive Function System (D-KEFS) test battery (1). Time series were extracted from 400 brain nodes and used in a co-activation pattern (CAP) analysis. Dynamic CAP metrics including dwell time (DT), frequency of occurrence, and transitions were computed. Multiple measurement models were compared based on model fit with indicators from the D-KEFS assigned a priori (shifting, inhibition, and fluency). Multiple structural equation models were computed with interactions between BMI and the dynamic CAP metrics predicting the three latent factors of shifting, inhibition, and fluency while controlling for age, sex, and head motion. Models were assessed for the main effects of BMI and CAP metrics predicting the latent factors. A three-factor model (shifting, inhibition, and fluency) resulted in the best model fit. Significant interactions were present between BMI and CAP 2 (lateral frontoparietal (L-FPN), medial frontoparietal (M-FPN), and limbic nodes) and CAP 5 (dorsal frontoparietal (D-FPN), midcingulo-insular (M-CIN), somatosensory motor, and visual network nodes) DTs associated with shifting. A higher BMI was associated with a positive relationship between CAP DTs and shifting. Conversely, in average and low BMI participants, a negative relationship was seen between CAP DTs and shifting. Our findings indicate that BMI moderates the relationship between brain dynamics of networks important for cognitive control and shifting, an index of cognitive flexibility. Furthermore, higher BMI is linked with altered brain dynamic patterns associated with shifting.


2021 ◽  
Vol 14 (1) ◽  
pp. 1-6
Author(s):  
Shakeela Ishrat ◽  
Marufa Hossain ◽  
Subrata Kumar Biswas

The objective of this study is to explore how hyperinsulinemia and insulin resistance relate to the clinical, endocrine and metabolic factors in the infertile women with polycystic ovary syndrome. This study was conducted on 121 consecutive infertile women with polycystic ovary syndrome attending the Infertility unit from January 2017 to December 2017. They were divided into two groups: insulin resistant and insulin sensitive. There was significant difference in body mass index and waist circumference between the two groups. Serum lipids were not associated with insulin resistance. Hyperinsulinemia was significantly associated with metabolic syndrome. Reducing body mass index and waist circumference may improve insulin resistance in infertile women with polycystic ovary syndrome. Screening the infertile women with polycystic ovary syndrome for hyperinsulinemia and insulin resistance and subsequent counseling is recommended to address the long-term risks of metabolic syndrome.


2015 ◽  
Vol 27 (3) ◽  
pp. 312-329
Author(s):  
Ryo Ishii

The purpose of this study was to test the hypothesis that the outcome of contemplating death during young adulthood, a change in time attitude, is influenced by present-orientation via the views of death. A total of 199 undergraduates responded to a questionnaire assessing time attitude and present-orientation before and after the assignment to contemplate death. The results of structural equation modeling revealed that present-orientation has a direct effect on the outcome, but the view of death does not have a mediated effect. The results of ANOVA also supported the direct effect of present-orientation. The analysis of the individual description showed that present-orientation has relevance with how to think life after contemplating death. The relationships between contemplating death and young adults’ ego identity which is closely related to time perspective were discussed.


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