scholarly journals A population-based retrospective study of the spread of COVID-19 from Wuhan to Henan province, China

2020 ◽  
Author(s):  
Fei Li ◽  
Xufei Du ◽  
Xinwei Geng ◽  
Min Zhang ◽  
Yun Zhao ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Age Groups ◽  
Population Based ◽  
Henan Province ◽  
Related Factors ◽  
News Reports ◽  
Epidemic Area ◽  
History Of ◽  
And Control ◽  
Time Information

Abstract The epidemic of COVID-19 has now spread globally and affected over 110 countries. As of Mar 10th, using publicly available data and official news reports in Henan province, we tracked a total of 1272 cases and a retrospective study was conducted to investigate the related factors in COVID-19 spread and control. We confirmed 554 primary patients had travel or residential history of Wuhan in the recent 2 weeks. Secondary cases accounted for 77.9% (141/181) among all the patients aged 61 or older, in whom contacted with unconfirmed returnees from Wuhan was responsible for 27.0% (38/141). The median incubate period is 7 (IQR, 4-10) days by analyzing time information in 469 cases. For 442 patients with discharge dates, the duration from onset to cure is 19 (IQR, 15-23) days. The time from onset to seeking care at a hospital varied in age groups, and differed between primary and secondary cases. Patients visiting different hospitals affected the time from seeking care to cure. Thus, our results showed the spread of COVID-19 and factors associated with outcomes of patients in Henan province, which helps to understand the epidemiological features outside of the epidemic area and control the disease in other regions and countries.

scholarly journals Awareness, Treatment, and Control of Hypertension Among 10663 Adults in Kherameh: A Population-Based Study

2021 ◽  
Author(s):  
Abbas Rezaianzadeh ◽  
Fatemeh Jafari ◽  
Seyed Ebrahim Sadeghi ◽  
Salar Rahimikazerooni ◽  
Ehsan Bahramali ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Chronic Diseases ◽  
Antihypertensive Drugs ◽  
Population Based ◽  
Related Factors ◽  
Cross Sectional ◽  
Dependent Variables ◽  
History Of ◽  
And Control ◽  
Second Degree

Abstract Background: Hypertension (HTN) is known to be a modifiable risk factor for Cardiovascular Disease (CVDs), stroke, and kidney disease. The present study aimed to determine awareness, treatment, and control of HTN and the related factors in Kherameh, Iran.Methods: This cross-sectional study was performed on 10663 individuals over 40 years of age using Kherameh cohort data. HTN was defined as either Systolic/Diastolic Blood Pressure (SBP/DBP) ≥140/90 mmHg or taking medications. Logistic regression was used to examine the relationship between awareness, treatment, and control and their related factors. Results: Awareness, treatment, and control rates were 80.3%, 78%, and 53.6%, respectively among the individuals with HTN. Age, gender, body mass index, and CVD were associated with all dependent variables in the regression model. In addition, occupation, diabetes, chronic diseases, history of CVD in the first- and second-degree relatives, and history of chronic diseases in the second-degree relatives were related to all dependent variables, except for treatment.Conclusion: The results indicated that despite the high level of awareness, the proportion of patients under treatment and control gradually decreased, such a way that about half of the patients had abnormal blood pressure. Hence, educational intervention is recommended to increase the patients’ awareness to ensure the continuous use of antihypertensive drugs in order to help control the disease more efficiently.

scholarly journals Age-Related Risk Factors and Complications of Patients With COVID-19: A Population-Based Retrospective Study

2022 ◽  
Vol 8 ◽  
Author(s):  
Han Zhang ◽  
Yingying Wu ◽  
Yuqing He ◽  
Xingyuan Liu ◽  
Mingqian Liu ◽  
...  
Keyword(s):  
Risk Factors ◽  
Retrospective Study ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Population Based ◽  
Male Gender ◽  
Poor Correlation ◽  
Age Related ◽  
Related Risk ◽  
Independent Risk Factors

Objective: To study the differences in clinical characteristics, risk factors, and complications across age-groups among the inpatients with the coronavirus disease 2019 (COVID-19).Methods: In this population-based retrospective study, we included all the positive hospitalized patients with COVID-19 at Wuhan City from December 29, 2019 to April 15, 2020, during the first pandemic wave. Multivariate logistic regression analyses were used to explore the risk factors for death from COVID-19. Canonical correlation analysis (CCA) was performed to study the associations between comorbidities and complications.Results: There are 36,358 patients in the final cohort, of whom 2,492 (6.85%) died. Greater age (odds ration [OR] = 1.061 [95% CI 1.057–1.065], p < 0.001), male gender (OR = 1.726 [95% CI 1.582–1.885], p < 0.001), alcohol consumption (OR = 1.558 [95% CI 1.355–1.786], p < 0.001), smoking (OR = 1.326 [95% CI 1.055–1.652], p = 0.014), hypertension (OR = 1.175 [95% CI 1.067–1.293], p = 0.001), diabetes (OR = 1.258 [95% CI 1.118–1.413], p < 0.001), cancer (OR = 1.86 [95% CI 1.507–2.279], p < 0.001), chronic kidney disease (CKD) (OR = 1.745 [95% CI 1.427–2.12], p < 0.001), and intracerebral hemorrhage (ICH) (OR = 1.96 [95% CI 1.323–2.846], p = 0.001) were independent risk factors for death from COVID-19. Patients aged 40–80 years make up the majority of the whole patients, and them had similar risk factors with the whole patients. For patients aged <40 years, only cancer (OR = 17.112 [95% CI 6.264–39.73], p < 0.001) and ICH (OR = 31.538 [95% CI 5.213–158.787], p < 0.001) were significantly associated with higher odds of death. For patients aged >80 years, only age (OR = 1.033 [95% CI 1.008–1.059], p = 0.01) and male gender (OR = 1.585 [95% CI 1.301–1.933], p < 0.001) were associated with higher odds of death. The incidence of most complications increases with age, but arrhythmias, gastrointestinal bleeding, and sepsis were more common in younger deceased patients with COVID-19, with only arrhythmia reaching statistical difference (p = 0.039). We found a relatively poor correlation between preexisting risk factors and complications.Conclusions: Coronavirus disease 2019 are disproportionally affected by age for its clinical manifestations, risk factors, complications, and outcomes. Prior complications have little effect on the incidence of extrapulmonary complications.

scholarly journals Effects of self-reported hearing or vision impairment on depressive symptoms: a population-based longitudinal study

2018 ◽  
Vol 28 (03) ◽  
pp. 343-355 ◽  
Author(s):  
J. H. Han ◽  
H. J. Lee ◽  
J. Jung ◽  
E.-C. Park
Keyword(s):  
Depressive Symptoms ◽  
Longitudinal Study ◽  
Hearing Impairment ◽  
Age Groups ◽  
Estimating Equation ◽  
Population Based ◽  
Vision Impairment ◽  
Sensory Impairment ◽  
Related Factors ◽  
Dual Sensory Impairment

Aims.The aims of this study were to investigate the effects of either hearing, vision or dual sensory impairment on depressive symptoms and to identify subgroups that are vulnerable and significantly affected.Methods.Data from the 2006–2014 Korean Longitudinal Study of Aging (KLoSA) were used and a total of 5832 individuals were included in this study. Depressive symptoms were assessed using the Center for Epidemiologic Studies Depression (CES-D10) scale. Sensory impairment was assessed according to the levels of self-reported hearing or vision, which were categorised as either good (excellent, very good or good) or poor (fair or poor). The changes in hearing or vision from records of previous survey were investigated. Changes from good to poor, which indicates new onset, were defined as hearing impairment or vision impairment. Interactions of changes in hearing and vision were considered in the analysis. Dual sensory impairment was indicated when hearing impairment and vision impairment both developed at the same time. Demographic, socioeconomic and health-related factors were considered as potential confounders and were adjusted for in the generalised estimating equation model.Results.Individuals with hearing impairment demonstrated significantly more severe depressive symptoms [β = 0.434, standard errors (s.e.) = 0.097, p < 0.001] than those who had good hearing. Those with vision impairment also showed significantly elevated depressive symptoms (β = 0.253, s.e. = 0.058, p < 0.001) than those with good vision. When the interactions between hearing and vision were considered, participants with dual sensory impairment showed significantly more severe depressive symptoms (β = 0.768, s.e. = 0.197, p < 0.001) than those with good hearing and vision. The effect of a single and dual sensory impairment on depressive symptoms was significant in both sexes and across age groups, except for vision impairment in male participants.Conclusions.Hearing, vision and dual sensory impairment are significantly associated with depressive symptoms. Our results suggest that treatment or rehabilitation of either hearing or vision impairment would help prevent depression.

On The Threshold of Democratic Fragility

2016 ◽  
pp. 328-348
Author(s):  
Asiru Hameed Tunde ◽  
Daniel Ochieng Orwenjo
Keyword(s):  
Presidential Election ◽  
Speech Act ◽  
Media Representation ◽  
Value Judgments ◽  
News Reports ◽  
A Value ◽  
Political Events ◽  
History Of ◽  
And Control ◽  
Election News

The recent events in the Nigerian political space are clear indications of a match towards the ‘unwanted'. These political events, such as the 2011 presidential elections resulted into the most violent post-elections killings in the history of Nigeria. In the light of this, media representation of that election may not be a value-free exercise but one imbued with value judgments or opinions which conveyed certain ideological leanings. It is against this background that the author examines the macrospeech acts which characterize the discourse of the 2011 post-presidential election news reports with a view to identifying and interpreting the prominent acts and their ideological imports. The study is situated within the broad frame of pragmatics and operationalises Searle Speech Act model in order to uncover the macrospeech acts in the news reports and how the acts covertly convey instances of prejudice and control.

scholarly journals Determinants of Restrictive Spirometric Pattern in a Sub-Saharan Urban Setting: A Cross-sectional Population-based Study

2016 ◽  
Vol 10 (1) ◽  
pp. 86-95 ◽  
Author(s):  
Eric Walter Pefura-Yone ◽  
Adamou Dodo Balkissou ◽  
Andre Pascal Kengne
Keyword(s):  
Heart Diseases ◽  
Population Based ◽  
Forced Expiratory Volume ◽  
Urban Setting ◽  
Sub Saharan Africa ◽  
Cross Sectional ◽  
History Of ◽  
Sub Saharan ◽  
And Control ◽  
Restrictive Pattern

Background Restrictive spirometric pattern is a risk factor for all-cause and cause-specific mortality. Objective We assessed the prevalence of restrictive pattern and investigated its determinants in a major sub-Saharan Africa city. Methods Participants were adults (≥ 19 years) who took part in a population-based survey in Yaounde (Cameroon) between December 2013 and April 2014. Restrictive pattern was based on a FVC below the lower limit of the normal (LLN) and a ratio forced expiratory volume in one second (FEV1)/FVC ≥ LLN (LLN-based restrictive pattern) or a FVC <80% and FEV1/FVC ≥ LLN (fixed cut-off based restrictive pattern). Determinants were investigated by logistic regressions. Results In all, 1003 participants [514 (51.2%) women] with a mean age of 33.7 years were included. The prevalence of restrictive pattern was 18.8% (95%CI: 16.6-21.2) based on LLN and 15.0% (13.0-17.2) based on fixed cut-off. LLN-based restrictive pattern was mild in 148 (78.3%) subjects, moderate in 35 (18.5%) and severe in 6 (3.2%). Determinants of LLN-based restrictive pattern were age ≥ 60 years [adjusted odds ratio 2.90 (95%CI 1.46-5.77), p=0.002), history of pulmonary tuberculosis [3.81(1.42-10.20), p=0.008], prevalent heart diseases [3.81 (1.20-12.12), p=0.024] and underweight [5.15(1.30-20.39), p=0.020]. Determinants were largely similar with slightly different effect sizes for fixed cut-off based restrictive pattern. Conclusion Restrictive pattern was very frequent in this city. Clinical implications These results enhance the needs to increase the efforts to prevent and control tuberculosis, cardiovascular diseases and underweight in this setting.

Treating the Elderly Patient with Acute Myelogenous Leukemia

Hematology ◽  
2010 ◽  
Vol 2010 (1) ◽  
pp. 62-69 ◽  
Author(s):  
Selina M. Luger
Keyword(s):  
Elderly Patient ◽  
Acute Myelogenous Leukemia ◽  
Intensive Therapy ◽  
Age Groups ◽  
The Elderly ◽  
Population Based ◽  
Myelogenous Leukemia ◽  
Best Interest ◽  
Related Factors ◽  
Acute Myelogenous

Abstract Decisions regarding the optimal treatment of acute myelogenous leukemia in the elderly patient requires the consideration of multiple factors. Population-based studies have demonstrated that, for all age groups, aggressive therapy results in improved survival and quality of life when compared with palliative care. The optimal induction and postremission regimen for older patients has yet to be determined. Furthermore, not all patients are candidates for such therapy. Consideration of patient and disease-related factors can help to determine the appropriateness of intensive therapy in a given patient. For those patients for whom aggressive induction therapy does not seem to be in their best interest, novel agents are being investigated that will hopefully address the issues of induction death and early relapse associated with these patient populations.

FC13-04 - Suicide risk in relation to age and psychiatric hospitalization

2011 ◽  
Vol 26 (S2) ◽  
pp. 1885-1885
Author(s):  
J. Reutfors ◽  
L. Brandt ◽  
K. Sparring Björkstén ◽  
A. Ekbom ◽  
U. Ösby
Keyword(s):  
Suicide Risk ◽  
Psychiatric Hospitalization ◽  
Conditional Logistic Regression ◽  
Age Groups ◽  
The Elderly ◽  
Population Based ◽  
Age Group ◽  
Post Discharge ◽  
History Of ◽  
Control Study

IntroductionSuicide risk is increased in patients with a history of psychiatric hospitalization.AimTo explore how suicide risk varies by age during psychiatric hospitalization and in the year post-discharge.MethodsThis is a population-based case-control study of all suicides (n = 20,675; 70% male) in Sweden aged ≥18 years during 1991–2003. Each suicide was individually matched to 10 population controls by age, sex, and county of residence. Discharge diagnoses of a mental disorder (except dementia and other organic disorders) in the year prior to suicide were identified by register linkage. Odds ratios (OR) were calculated by conditional logistic regression to estimate the relative risk of suicide in those with psychiatric diagnoses compared to the general population. ORs were estimated by age group (18–34 years, 35–49 years, 50–64 years, and ≥ 65 years) and timing of the suicide in relation to discharge.ResultsDuring hospitalization, the youngest age group had the greatest suicide risk elevation [OR 64 (95% CI 44-92)]. In the first month post-discharge, the oldest age group had the highest suicide risk elevation [OR 162 (95% 66–399) in the first week and OR 127 (95% 67–242) in the second to fourth weeks]. In the remaining eleven months, suicide risk elevation was lower and relatively similar in different age groups.ConclusionsDuring the year following psychiatric hospitalization, an especially high attention should be paid to the suicide risk of the elderly patients in the first month post-discharge.

scholarly journals Pregnancy Outcomes and Associated Factors for Uterine Rupture: An 8 Years Population-based Retrospective Study

2021 ◽  
Author(s):  
Sheng Wan ◽  
Mengnan Yang ◽  
Jindan Pei ◽  
Xiaobo Zhao ◽  
Chenchen Zhou ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Uterine Rupture ◽  
Obstetric Care ◽  
Developed Countries ◽  
Population Based ◽  
Fetal Heart Rate Monitoring ◽  
Fetal Complications ◽  
History Of ◽  
Scarred Uterus ◽  
Obstetrical Emergency

Abstract Background: Uterine rupture is an obstetrical emergency with serious undesired complications for laboring mothers resulting in fatal maternal and neonatal outcomes. The aim of this study was to assess the incidence of uterine rupture, its association with previous uterine surgery and vaginal birth after caesarean section (VBAC), and the maternal and perinatal implications. Methods: This is a population-based retrospective study. All pregnant women treated for ruptured uterus in one center between 2013 and 2020 were included. Their information retrieved from the medical records department were retrospectively reviewed.Results: A total of 209,112 deliveries were included and 41 cases of uterine rupture were identified. The incidence of uterine rupture was 1.96/10 000 births. 16 (39.0%) had maternal and fetal complications. There were no maternal deaths secondary to uterine rupture, while perinatal fatality related to uterine rupture was 7.3%. Among all case, 38 (92.7%) were scarred uterus and 3 (7.3%) were unscarred uterus. The most common cause of uterine rupture was previous cesarean section, while cases with a history of laparoscopic myomectomy were more likely to have serious adverse outcome. 24 (59%) of the ruptures occurred in anterior lower uterine segment. Fetal heart rate monitoring changes were the most reliable signs for rupture.Conclusions: Incidence of uterine rupture in the study area was consistent with developed countries. Further improvement in obstetric care and strong collaboration with referring health facilities was needed to ensure maternal and perinatal safety.

scholarly journals Anaemia in solitary acyanotic ventricular septal defect in comorbid with pneumonia or pulmonary hypertension: A retrospective study of 75 paediatric cases

F1000Research ◽  
2019 ◽  
Vol 8 ◽  
pp. 101
Author(s):  
Geoffrey Joseph Changwe ◽  
Haizhou Zhang ◽  
Hongxin Li ◽  
Zeeshan Farhaj ◽  
Marlvin Anemey Tewara ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Retrospective Study ◽  
Young Children ◽  
Heart Defects ◽  
Threshold Level ◽  
Older Children ◽  
Surgical Closure ◽  
History Of ◽  
A Prospective Study ◽  
And Control

Background: Ventricular septal defects (VSD) are the second commonest congenital heart defects after bicuspid aortic valve. When left unrepaired, they can undergo spontaneous closure or elicit a spectrum of complications including pneumonia (PNA) or pulmonary hypertension (PH) with subsequent anaemia. In this retrospective study, we aim to establish and compare the prevalence of anaemia in patients with solitary acyanotic VSD in comorbid with PNA or PH. Methods: A total of 75 case files of patients with solitary acyanotic VSD, who underwent surgical closure or device occlusion had haemoglobin level analysed prior to the procedure. The cohort included patients with (history of) PNA and PH, and asymptomatic. The cohort included 27 females and 48 males with mean age and weight of 8.3±5.72 (3-24) months and 5.9±3.9 (2.7-17.8) kilograms, respectively. Depending on  associated complication and age, the cohort was divided: PNA (A), PH (B) and Control (C); and (I) young children (≥3-6≤) and (II) older children (>6-≤24) months. We used 95 and 105 grams per litre as haemoglobin lower threshold level for (I) and (II), respectively. Results: According to data analysis 27 patients (36%) in total had anaemia. Of the anaemia cohort 16 (59.3%) had PNA, 9 (33.3%) PH and 2 (7.4%) were asymptomatic. Of the cohort, 42 were young children, with anaemia prevalence of 19/42 (45.2%), while 24.2% of the older children had anaemia. Intergroup ANOVA independent sample t-test was significant (p<0.05). In addition, intergroup Tukey HSD test for haemoglobin: A/B (p>0.05), A/C (p<0.01), B/C (p<0.01).  Conclusion: Paediatric patients with acyanotic VSD in comorbid with PNA or PH are 8 and 4 times more susceptible to develop anaemia compared to asymptomatic counterparts. Susceptibility is even higher among young children (3-6months). However, a prospective study is needed to validate our findings.

scholarly journals Genotype-specific prevalence of human papillomavirus infection in asymptomatic Peruvian women: a community-based study

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Juana del Valle-Mendoza ◽  
Lorena Becerra-Goicochea ◽  
Miguel Angel Aguilar-Luis ◽  
Luis Pinillos-Vilca ◽  
Hugo Carrillo-Ng ◽  
...  
Keyword(s):  
High Risk ◽  
Age Groups ◽  
Population Based ◽  
Community Based ◽  
Papillomavirus Infection ◽  
Potential Risk Factors ◽  
History Of ◽  
Hpv Types ◽  
High Risk Hpv ◽  
Oncogenic Hpv

Abstract Objective To determine the general and genotype-specific prevalence of HPV and to identify potential risk factors for the infection in a population-based screening of Peruvian women. Results A total of 524 samples were analyzed by PCR and a total of 100 HPV positive samples were found, of which 89 were high-risk, 19 were probably oncogenic, 9 were low-risk and 27 other HPV types. The 26–35 and 36–45 age groups showed the highest proportion of HPV positive samples with a total of 37% (37/100) and 30% (30/100), respectively. Moreover, high-risk HPV was found in 33.7% of both groups and probably oncogenic HPV in 52.6% and 31.6%, respectively. High-risk HPV were the most frequent types identified in the population studied, being HPV-52, HPV-31 and HPV-16 the most commonly detected with 17.6%, 15.7% y 12.9%, respectively. Demographic characteristics and habits were assessed in the studied population. A total of 62% high-risk HPV were detected in married/cohabiting women. Women with two children showed the highest proportion (33.8%) of high-risk HPV, followed by women with only one child (26.9%). Those women without history of abortion had a higher frequency of high-risk HPV (71.9%), followed by those with one abortion (25.8%).

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