scholarly journals Herd-level risk factors for chronic pleurisy in finishing pigs: a case-control study

2020 ◽  
Author(s):  
Outi Hälli ◽  
Minna Haimi-Hakala ◽  
Claudio Oliviero ◽  
Mari Heinonen
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Swine Influenza Virus ◽  
Clinical Signs ◽  
Case Control ◽  
Meat Inspection ◽  
Common Finding ◽  
Finishing Pigs ◽  
Herd Level ◽  
Control Study

Abstract Background Chronic pleurisy is a common finding in slaughtered pigs in post-mortem meat inspection. The prevalence of pleurisy has been increasing during the last decade also in Finland. The aim of this prospective case-control study was to search for environmental, infectious and management-related herd-level risk factors for pleurisy in the slaughterhouse. Altogether 46 Finnish pig herds, including 25 control (low pleurisy prevalence in meat inspection) and 21 case (high pleurisy) herds, were enrolled in the study and visited during the tenth week of the rearing period of finishing pigs. Herd personnel were asked about basic herd information, management and environmental factors. Selected pigs were examined clinically, environmental parameters were measured and 15 blood samples per herd were taken during herd visits. Antibodies against Actinobacillus pleuropneumonia serotype 2 (APP2) and ApxIV toxin and swine influenza virus were measured. After the slaughter of study pigs, meat inspection results of the batch were gathered from slaughterhouses. Multivariate logistic regression model was built to identify possible risk factors for a herd to be a case herd (i.e. having high pleurisy values). Results Finishing herd type and herd size were observed to act as risk factors. None of clinical signs of pigs, management-related factors or environmental measurements were associated with herd status. Conclusions As previously known, in endemic and subclinical infections such as APP, herd factors are important, but detailed risk factors seem to be difficult to identify.

scholarly journals Herd-level risk factors for chronic pleuritis in finishing pigs: a case-control study

2020 ◽  
Author(s):  
Outi Hälli ◽  
Minna Haimi-Hakala ◽  
Claudio Oliviero ◽  
Mari Heinonen
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Meat Inspection ◽  
Common Finding ◽  
Finishing Pigs ◽  
Related Factors ◽  
Herd Level ◽  
Infection Pressure ◽  
Control Study

Abstract Background Chronic pleuritis is a common finding in slaughtered pigs in post-mortem meat inspection. The prevalence of pleuritis has been increasing during the last decade also in Finland. The aim of this prospective case-control study was to search for environmental, infectious and management-related herd-level risk factors for pleuritis in the slaughterhouse. Altogether 46 Finnish pig herds, including 25 control (low pleuritis prevalence in meat inspection) and 21 case (high pleuritis) herds, were enrolled in the study and visited during the tenth week of the rearing period of finishing pigs. Herd personnel were asked about basic herd information, management and environmental factors. Selected pigs were examined clinically, environmental parameters were measured and 15 blood samples per herd were taken during herd visits. Antibodies against Actinobacillus pleuropneumonia serotype 2 (APP2) and ApxIV toxin and swine influenza virus were measured. After the slaughter of study pigs, meat inspection results of the batch were gathered from slaughterhouses. Multivariate logistic regression models were built to identify possible risk factors for a herd to be a case herd ( i.e. having high pleuritis values).Results Finishing herd type, herd size and APP2 seropositivity were observed to act as risk factors. In addition to these, general herd-level factors, flank biting and high APP2 antibody prevalence of the herd tended to be associated with the risk of the herd being a case herd. None of the other clinical signs of pigs, management-related factors or environmental measurements were associated with herd status.Conclusions As previously known, in endemic and subclinical infections such as APP, herd and management-related factors are important in building up infection pressure, but single risk factors seem to be difficult to identify. However, as flank biting was more common in high pleuritis herds, part of disease susceptibility is likely mediated via stress.

scholarly journals Herd-level risk factors for chronic pleurisy in finishing pigs: a case-control study

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Outi Hälli ◽  
Minna Haimi-Hakala ◽  
Claudio Oliviero ◽  
Mari Heinonen
Keyword(s):  
Risk Factors ◽  
Case Control Study ◽  
Case Control ◽  
Finishing Pigs ◽  
Herd Level ◽  
Control Study

scholarly journals Risk factors for postpartum sepsis: A nested case control study

2020 ◽  
Author(s):  
Samina Bakhtawar ◽  
Sana Sheikh ◽  
Rahat Qureshi ◽  
Zahra Hoodbhoy ◽  
Beth Payne ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Sign ◽  
Case Control Study ◽  
Multivariable Analysis ◽  
Clinical Signs ◽  
Case Control ◽  
Postpartum Women ◽  
Discriminative Performance ◽  
Maternal Deaths ◽  
Control Study

Abstract Background: Majority (99%) of maternal deaths occur in low and middle income countries. The three most important causes of maternal deaths in these regions are postpartum hemorrhage, pre-eclampsia and puerperal sepsis. There are several diagnostic criteria used to identify sepsis and one of the commonly used criterion is systematic inflammatory response syndrome (SIRS). However, these criteria require laboratory investigations which may not be feasible in resource constrained settings. Therefore, this study aimed to develop a model based on risk factors and clinical signs and symptoms that can identify sepsis early among postpartum women.Methods: A case control study was nested in an ongoing cohort of 4000 postpartum women who delivered or were admitted in study hospital. According to standard criteria of SIRS, 100 women with sepsis (cases) and 498 women without sepsis (controls) were recruited from January to July 2017. Information related to socio-demographic status, antenatal care and maternal life styles were obtained via interview while pregnancy and delivery related information, comorbid and clinical sign and symptoms were retrieved from ongoing cohort. Multivariable logistic regression was performed and discriminative performance of the model was assessed using area under the curve (AUC) of the receiver operating characteristic (ROC).Results: Multivariable analysis revealed that 1-4 antenatal visits (95% CI 0.01 - 0.62), 3 or more vaginal examinations (95% CI 1.21 - 3.65), home delivery (95% CI 1.72-50.02), preterm delivery, diabetes in pregnancy (95% CI 1.93-20.23), lower abdominal pain (95% CI 1.15 - 3.42)) vaginal discharge (95% CI 2.97-20.21), SpO2 <93% (95% CI 4.80-37.10) and blood glucose were significantly associated with sepsis. AUC was 0.84 (95% C.I 0.80-0.89) which indicated that risk factors and clinical sign and symptoms based model has adequate ability to discriminate women with and without sepsis.Conclusion: This study developed a non-invasive tool which can identify postpartum women with sepsis as accurately as SIRS criteria with good discriminative ability. Once validated, this tool has a potential to be scaled up for community use by frontline health care workers.

Case-control study to determine herd-level risk factors for bovine respiratory disease in nursing beef calves on cow-calf operations

2018 ◽  
Vol 252 (8) ◽  
pp. 989-994 ◽  
Author(s):  
Amelia R. Woolums ◽  
Roy D. Berghaus ◽  
David R. Smith ◽  
Russell F. Daly ◽  
Gerald L. Stokka ◽  
...  
Keyword(s):  
Risk Factors ◽  
Respiratory Disease ◽  
Case Control Study ◽  
Bovine Respiratory Disease ◽  
Case Control ◽  
Beef Calves ◽  
Herd Level ◽  
Cow Calf ◽  
Control Study

scholarly journals Case-Control Study of Risk Factors Associated with Feline and Canine Chronic Kidney Disease

2010 ◽  
Vol 2010 ◽  
pp. 1-9 ◽  
Author(s):  
Paul C. Bartlett ◽  
James W. Van Buren ◽  
Andrew D. Bartlett ◽  
Chun Zhou
Keyword(s):  
Risk Factors ◽  
Weight Loss ◽  
Case Control Study ◽  
Clinical Signs ◽  
Case Control ◽  
Factors Associated ◽  
History Of ◽  
Bad Breath ◽  
Dog Owners ◽  
Control Study

An age-matched case-control study was initiated to determine the major risk factors associated with CKD in cats and dogs and to determine what clinical signs cat and dog owners observed before their veterinarian diagnosed their pet with CKD. When compared to controls, the feline cases were more likely to have had polydipsia and polyuria in the year before the owners' cats were diagnosed with CKD. In the dogs, increased water intake, increased urination, small size and a recent history of weight loss and bad breath were noticed by the dog owners before veterinary CKD diagnosis. Dog owners recognized abnormal drinking and urination behavior over half a year before their pet's veterinary diagnosis with CKD, and they recognized weight loss almost 4 months before CKD diagnosis. Bad breath was noticed 1.2 years before recognition of CKD by a veterinarian. Given that earlier CKD diagnosis should have been possible in most cases, clinical trials should proceed to measure the efficacy of early interventions.

scholarly journals Risk factors for postpartum sepsis: A nested case-control study

2020 ◽  
Author(s):  
Samina Bakhtawar ◽  
Sana Sheikh ◽  
Rahat Qureshi ◽  
Zahra Hoodbhoy ◽  
Beth Payne ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Sign ◽  
Case Control Study ◽  
Multivariable Analysis ◽  
Clinical Signs ◽  
Case Control ◽  
Postpartum Women ◽  
Discriminative Performance ◽  
Maternal Deaths ◽  
Control Study

Abstract Background: The Majority (99%) of maternal deaths occur in low and middle-income countries. The three most important causes of maternal deaths in these regions are postpartum hemorrhage, pre-eclampsia and puerperal sepsis. There are several diagnostic criteria used to identify sepsis and one of the commonly used criteria is systematic inflammatory response syndrome (SIRS). However, these criteria require laboratory investigations that may not be feasible in resource-constrained settings. Therefore, this study aimed to develop a model based on risk factors and clinical signs and symptoms that can identify sepsis early among postpartum women. Methods: A case-control study was nested in an ongoing cohort of 4000 postpartum women who delivered or were admitted to the study hospital. According to standard criteria of SIRS, 100 women with sepsis (cases) and 498 women without sepsis (controls) were recruited from January to July 2017. Information related to the socio-demographic status, antenatal care and use of tobacco were obtained via interview while pregnancy and delivery related information, comorbid and clinical sign and symptoms were retrieved from the ongoing cohort. Multivariable logistic regression was performed and discriminative performance of the model was assessed using area under the curve (AUC) of the receiver operating characteristic (ROC). Results: Multivariable analysis revealed that 1-4 antenatal visits (95% CI 0.01 - 0.62) , 3 or more vaginal examinations (95% CI 1.21 - 3.65), home delivery (95% CI 1.72-50.02), preterm delivery, diabetes in pregnancy (95% CI 1.93-20.23), lower abdominal pain (95% CI 1.15 - 3.42)) vaginal discharge (95% CI 2.97-20.21), SpO2 <93% (95% CI 4.80-37.10) and blood glucose were significantly associated with sepsis. AUC was 0.84 (95% C.I 0.80-0.89) which indicated that risk factors and clinical sign and symptoms-based model has adequate ability to discriminate women with and without sepsis. Conclusion: This study developed a non-invasive tool that can identify postpartum women with sepsis as accurately as SIRS criteria with good discriminative ability. Once validated, this tool has the potential to be scaled up for community use by frontline health care workers.

scholarly journals A case-control study to identify risk factors for acute salmonellosis in New Zealand dairy herds, 2011–2012

2016 ◽  
Vol 144 (10) ◽  
pp. 2154-2164
Author(s):  
M. A. STEVENSON ◽  
P. L. MORGAN ◽  
J. SANHUEZA ◽  
G. E. OAKLEY ◽  
R. S. BATEMAN ◽  
...  
Keyword(s):  
Risk Factors ◽  
New Zealand ◽  
Case Control Study ◽  
Multivariable Analysis ◽  
Palm Kernel ◽  
Case Control ◽  
Dairy Herds ◽  
Herd Level ◽  
Supplementary Feed ◽  
Control Study

SUMMARYIn late 2011 the New Zealand Ministry for Primary Industries reported an increase in confirmed laboratory diagnoses of salmonellosis in dairy herds. To identify risk factors for herd-level outbreaks of salmonellosis we conducted a case-control study of New Zealand dairy herds in 2011–2012. In a multivariable analysis, use of continuous feed troughs [adjusted odds ratio (aOR) 6·2, 95% confidence interval (CI) 2·0–20], use of pelletized magnesium supplements (aOR 10, 95% CI 3·3–33) and use of palm kernel meal as a supplementary feed (aOR 8·7, 95% CI 2·5–30) were positively associated with a herd-level outbreak of salmonellosis between 1 July 2011 and 31 January 2012. We conclude that supplementary feeds used on dairy farms (regardless of type) need to be stored and handled appropriately to reduce the likelihood of bacterial contamination, particularly from birds and rodents. Magnesium supplementation in the pelletized form played a role in triggering outbreaks of acute salmonellosis in New Zealand dairy herds in 2011–2012.

Human Toxocara infection of the central nervous system and neurological disorders: a case-control study

Parasitology ◽  
1997 ◽  
Vol 115 (5) ◽  
pp. 537-543 ◽  
Author(s):  
J.-F. MAGNAVAL ◽  
V. GALINDO ◽  
L. T. GLICKMAN ◽  
M. CLANET
Keyword(s):  
Risk Factors ◽  
Central Nervous System ◽  
Nervous System ◽  
Case Control Study ◽  
Neurological Diseases ◽  
Clinical Signs ◽  
Multivariate Logistic Regression Analysis ◽  
Case Control ◽  
Case Status ◽  
Control Study

Infection with Toxocara canis is a common world-wide human helminthiasis, which rarely elicits central nervous system (CNS) impairment. A case-control study to investigate this discrepancy was carried out, in which the cases were 27 adult neurological inpatients for whom a definite aetiological diagnosis was lacking, and for whom positive immunodiagnosis of toxocariasis had been obtained, both in cerebrospinal fluid (CSF) and in serum. Two control groups were used. Controls were adult inpatients with other neurological diseases who had no evidence of T. canis infection of the CNS. Multivariate logistic regression analysis did not reveal any positive relation between case status and clinical signs. A significant association was observed between case status and an elevated CSF cell count. Rural residence, ownership of dogs, and dementia were shown to be risk factors for toxocaral infection of CNS. These results suggest that migration of T. canis larvae in the human brain does not frequently induce a recognizable neurological syndrome but is correlated with the association of several risk factors including exposure to dogs, a status possibly responsible for repeated low-dose infections.

Sign in / Sign up

Export Citation Format

Share Document