scholarly journals Estimation of COVID-19 outbreak size in Harbin, China

2020 ◽  
Author(s):  
Haitao Song ◽  
Zhongwei Jia ◽  
Zhen Jin

Abstract Background: Since the first level response to public health emergencies (FLRPHE) was launched on January 25, 2020 in Heilongjiang province, China, the outbreak of COVID-19 seems to be under control. However, an outbreak of COVID-19 caused by imported case developed in Harbin during April 2020. Here, we provide an estimate of the COVID-19 outbreak size in Harbin in April based on the number of found infected cases, assess the proportion of found and unfound infected cases in infected cases and evaluate the effective reproduction number which shows the transmission risk of COVID-19. Methods: We used data from April 9 to April 30, 2020, on the number of found infected cases from the outbreak in Harbin to infer the number of infections in Harbin in the outbreak of COVID-19 and give the proportion of found and unfound infected cases in infected cases. Data on found infected cases were obtained from the the reports of Health Commission of Heilongjiang Province. A Susceptible-Unfound infected-Found infected-Removed model was used to fit the data on found infected cases of COVID-19 in Harbin using the least square method and simulate the transmission of COVID-19. The effective reproduction number was estimated. Results: The COVID-19 outbreak size estimated in Harbin in April reaches 174, where 54% of infected cases were found and 46% of infected cases were not found out. Our findings suggest that the effective reproduction number decreased drastically in contrast with the value of 3.6 on April 9 after that the effective interventions were implemented by Heilongjiang province government. Finally, the effective reproduction number arrived the value of 0.04 which is immensely below the threshold value 1, which means that Heilongjiang province government got the outbreak of COVID-19 in Harbin under control. Conclusions: The COVID-19 outbreak size in Harbin based on the assumptions that infected people with COVID-19 in the incubation period have the same infectivity with infectious people with COVID-19 could have been overestimated. As an increasing number of imported infected cases got into China and a growing number of asymptomatic infected people were found, our study provides evidence that unfound infected cases would increase the risk of local outbreak of COVID-19 in China.

Author(s):  
Parth Vipul Shah

ABSTRACT Objectives: We study the effect of the coronavirus disease 2019 (COVID-19) in India and model the epidemic to guide those involved in formulating policy and building health-care capacity. Methods: This effect is studied using the Susceptible-Exposed-Infected-Recovered (SEIR) compartmental model. We estimate the infection rate using a least square method with Poisson noise and calculate the reproduction number. Results: The infection rate is estimated to be 0.270 and the reproduction number to be 2.70. The approximate peak of the epidemic will be August 9, 2020. A 25% drop in infection rate will delay the peak by 11 d for a 1-mo intervention period. The total infected individuals in India will be 9% of the total population. Conclusions: The predictions are sensitive to changes in the behavior of people and their practice of social distancing.


2011 ◽  
Vol 80-81 ◽  
pp. 1345-1349
Author(s):  
Hao Yang ◽  
Lei Pei

The accuracy of edge detection determines the accuracy of actual dimension measurement,in order to improve the measuring accuracy, this paper proposes a fast algorithm of detecting the glass bottle dimension based on Zernike moments. Firstly, combines the traditional Zernike moment-based method with Otsu adaptive threshold algorithm and a new fast algorithm for edge detection is proposed. Then uses this fast algorithm to detect the edge of glass bottle with subpixel-level and uses the least square method to fit ellipses formed by the glass bottle mouth and bottom. Calibrated the system with standard gauge block and obtain the actual dimension at last. Experimental results show that the improved algorithm not only can make the edge detection reach the subpixel-level accuracy, but also can avoid the edge misidentification and inefficient causing by repeatedly manual adjustments to select the threshold value when detecting the edge. Making a rapid, accurate, non-contact measuring system becomes a reality.


2020 ◽  
Author(s):  
Parth Vipul Shah

AbstractWe study the effect of the coronavirus disease 2019 (COVID-19) in India using the SEIR compartmental model. After it’s outbreak in Wuhan, China, it has been imported to India which is a densely populated country. India is fighting against this disease by ensuring nationwide social distancing. We estimate the infection rate to be 0.258 using a least square method with Poisson noise and estimate the reproduction number to be 2.58. We approximate the peak of the epidemic to be August 11, 2020. We estimate that a 25% drop in infection rate will delay the peak by 38 days for a 1 month intervention period. We estimate that the total individuals infected in India will be approximately 9% of the total population.


Author(s):  
Salih Djilali ◽  
Soufiane Bentout ◽  
Sunil Kumar ◽  
Tarik Mohammed Touaoula

In this research, we are interested in discussing the evolution of the COVID-19 infection cases and predicting the spread of COVID-19 disease in Algeria and India. To this aim, we will approximate the transmission rate in terms of the measures taken by the governments. The least square method is used with an accuracy of 95% for fitting the artificial solution with the real data declared by WHO for the purpose of approximating the density of asymptomatic individuals for COVID-19 disease. As a result, we obtained the different values of the basic reproduction number (BRN) corresponding to each measure taken by the governments. Moreover, we estimate the number of asymptomatic infected persons at the epidemic peak for each country. Further, we will determine the needed ICU beds (intense medical carte beds) and regular treatment beds. Also, we provide the outcome of governmental strategies in reducing the spread of disease. Combining all these components, we offer some suggestions about the necessity of using the recently discovered vaccines as Pfizer/Bioentec and Moderna for limiting the spread of the COVID-19 disease in the studied countries.


2015 ◽  
Vol 2015 ◽  
pp. 1-11 ◽  
Author(s):  
Zhiming Li ◽  
Zhidong Teng ◽  
Xiaomei Feng ◽  
Yingke Li ◽  
Huiguo Zhang

In order to investigate the transmission mechanism of the infectious individual with Ebola virus, we establish an SEIT (susceptible, exposed in the latent period, infectious, and treated/recovery) epidemic model. The basic reproduction number is defined. The mathematical analysis on the existence and stability of the disease-free equilibrium and endemic equilibrium is given. As the applications of the model, we use the recognized infectious and death cases in Guinea to estimate parameters of the model by the least square method. With suitable parameter values, we obtain the estimated value of the basic reproduction number and analyze the sensitivity and uncertainty property by partial rank correlation coefficients.


1981 ◽  
Vol 20 (06) ◽  
pp. 274-278
Author(s):  
J. Liniecki ◽  
J. Bialobrzeski ◽  
Ewa Mlodkowska ◽  
M. J. Surma

A concept of a kidney uptake coefficient (UC) of 131I-o-hippurate was developed by analogy from the corresponding kidney clearance of blood plasma in the early period after injection of the hippurate. The UC for each kidney was defined as the count-rate over its ROI at a time shorter than the peak in the renoscintigraphic curve divided by the integral of the count-rate curve over the "blood"-ROI. A procedure for normalization of both curves against each other was also developed. The total kidney clearance of the hippurate was determined from the function of plasma activity concentration vs. time after a single injection; the determinations were made at 5, 10, 15, 20, 30, 45, 60, 75 and 90 min after intravenous administration of 131I-o-hippurate and the best-fit curve was obtained by means of the least-square method. When the UC was related to the absolute value of the clearance a positive linear correlation was found (r = 0.922, ρ > 0.99). Using this regression equation the clearance could be estimated in reverse from the uptake coefficient calculated solely on the basis of the renoscintigraphic curves without blood sampling. The errors of the estimate are compatible with the requirement of a fast appraisal of renal function for purposes of clinical diagknosis.


2015 ◽  
Vol 5 (2) ◽  
pp. 1
Author(s):  
Miftahol Arifin

The purpose of this research is to analyze the influence of knowledge management on employee performance, analyze the effect of competence on employee performance, analyze the influence of motivation on employee performance). In this study, samples taken are structural employees PT.centris Kingdom Taxi Yogyakarta. The analysis tool in this study using multiple linear regression with Ordinary Least Square method (OLS). The conclusion of this study showed that the variables of knowledge management has a significant influence on employee performance, competence variables have an influence on employee performance, motivation variables have an influence on employee performance, The analysis showed that the variables of knowledge management, competence, motivation on employee performance.Keywords: knowledge management, competence, motivation, employee performance.


2020 ◽  
Vol 1 (1) ◽  
pp. 128-140 ◽  
Author(s):  
Mohammad Hatami ◽  
◽  
D Jing ◽  

In this study, two-phase asymmetric peristaltic Carreau-Yasuda nanofluid flow in a vertical and tapered wavy channel is demonstrated and the mixed heat transfer analysis is considered for it. For the modeling, two-phase method is considered to be able to study the nanoparticles concentration as a separate phase. Also it is assumed that peristaltic waves travel along X-axis at a constant speed, c. Furthermore, constant temperatures and constant nanoparticle concentrations are considered for both, left and right walls. This study aims at an analytical solution of the problem by means of least square method (LSM) using the Maple 15.0 mathematical software. Numerical outcomes will be compared. Finally, the effects of most important parameters (Weissenberg number, Prandtl number, Brownian motion parameter, thermophoresis parameter, local temperature and nanoparticle Grashof numbers) on the velocities, temperature and nanoparticles concentration functions are presented. As an important outcome, on the left side of the channel, increasing the Grashof numbers leads to a reduction in velocity profiles, while on the right side, it is the other way around.


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