scholarly journals Comparing Infant and Toddler Sleep Patterns Prior to and During the First Wave of Home Confinement Due to COVID-19 in Spain

2021 ◽  
Author(s):  
Pia Cassanello ◽  
Ruiz-Botia Irene ◽  
Sala-Castellvi Pere ◽  
Martin Juan Carlos ◽  
Jose Martínez-Sanchez ◽  
...  
Keyword(s):  
Infants And Toddlers ◽  
Long Term Effects ◽  
Sleep Patterns ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Relevant Role ◽  
Children’S Sleep

Abstract IntroductionRecent literature has shown that sleep patterns are shaped during the first years of life, playing a relevant role in children’s functioning. We focused on comparing sleep patterns in infants and toddlers in Spain before and during COVID-19 home confinement to assess the immediate impact on sleep patterns. Methodse compared data from two cross-sectional surveys from parents of 1,658 children three to 36 months of age from Spain. One conducted before COVID-19 (2017-2018, n=1,380) and another during COVID-19 pandemic (March-May of 2020, n=254). We used an internet self-administrated questionnaire using the Brief Infant Sleep Questionnaire (BISQ) criteria in both surveys.ResultsDuring confinement infants and toddlers went to sleep later (median bedtime 21.5 before confinement vs. 21.6 during confinement p=0.004). We found a statistically significant increase in infants’ and toddlers’ sleep latency by >30 minutes during confinement (p<0.001). Based on the recommended BISQ criteria for classifying inadequate sleep patterns, we observed a statistically significant increase in poor sleepers meeting at least one criterion during confinement (p<0.001). ConclusionsParents during COVID-19 home confinement reported several factors affecting the quality of their children’s sleep. Follow-up studies can help understand the potential long-term effects of the COVID-19 pandemic on sleep patterns.

scholarly journals Comparing Infant and Toddler Sleep Patterns Prior To and During The First Wave of Home Confinement Due To COVID-19 in Spain

2021 ◽  
Author(s):  
Pia Cassanello ◽  
Irene Ruiz-Botia ◽  
Pere Sala-Castellvi ◽  
Juan Carlo Martin ◽  
Jose Maria Martínez-Sanchez ◽  
...  
Keyword(s):  
Parental Perception ◽  
Infants And Toddlers ◽  
Long Term Effects ◽  
Sleep Patterns ◽  
Cross Sectional ◽  
Relevant Role ◽  
Perception Of Sleep

Abstract Introduction: Recent literature has shown that sleep patterns are shaped during the first years of life, playing a relevant role in children’s functioning. We focused on comparing sleep patterns in infants and toddlers in Spain before and during COVID-19 home confinement to assess the immediate impact on sleep patterns. Methods We compared data from two cross-sectional surveys from parents of 1,658 children three to 36 months of age from Spain. One conducted before COVID-19 (2017–2018, n = 1,380) and another during COVID-19 pandemic (March-May of 2020, n = 254). We used an internet self-administrated questionnaire using the Brief Infant Sleep Questionnaire (BISQ) criteria in both surveys. Results During confinement infants and toddlers went to sleep later (median bedtime 21:30 before confinement vs. 21.36 during confinement (p = 0.004)). More infants and toddlers showed longer sleep latencies (> 30 minutes) during confinement median 33.9% versus 12.3% (p < 0.001). Based on the recommended BISQ criteria, we observed an increase in poor sleepers meeting at least one criterion of inadequate patterns during confinement (p < 0.001). Parental perception of a child’s sleep as problematics were 39.4% and 44.1% (adjusted p = 0.363) before and under lockdown, respectively. Conclusions Home confinement generally affected infant’s and toddler’s sleep patterns negatively, however parents didn’t report worse perception of sleep quality of their children. Follow-up studies can help understand the potential long-term effects of the COVID-19 pandemic on sleep patterns.

scholarly journals Study protocol: The Dutch 20|30 Postmeningitis study: a cross-sectional follow-up of two historical childhood bacterial meningitis cohorts on long-term outcomes

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
O. El Tahir ◽  
R. C. J. de Jonge ◽  
S. Ouburg ◽  
S. A. Morré ◽  
A. M. van Furth
Keyword(s):  
Quality Of Life ◽  
Bacterial Meningitis ◽  
Prediction Models ◽  
Adverse Outcomes ◽  
Long Term Effects ◽  
Long Term Outcomes ◽  
Cross Sectional

Abstract Background Bacterial meningitis (BM) is a serious, life-threatening infectious disease of the central nervous system that often occurs in young children. The most common severe to moderate sequelae following BM are sensorineural hearing loss, neuromotor disabilities and mental retardation, while subtle sequelae include academic and behavioral disabilities. It is largely unknown whether these more subtle sequelae persist into adolescence and adulthood. Therefore, this study will investigate the very long-term effects of childhood BM in later life. Better understanding of long-term effects and early identification of adverse outcomes after BM are essential for more timely interventions. Additionally, certain single nucleotide polymorphisms (SNPs) are associated with disease severity and might predict adverse sequelae. These include SNPs in genes encoding for pathogen recognition and immune response upon infection. Accordingly, a secondary objective of this study is to investigate the role of genetic variation in BM and use any insights to predict short- and long-term outcomes. Methods In the Dutch 20|30 Postmeningitis study, adolescents and young adults (n = 947) from two historical cohorts with a prior episode of BM during childhood will be enrolled into a cross-sectional follow-up investigation using mainly questionnaires that examine executive and behavioral functioning, health-related quality of life, subjective hearing, mood and sleeping disorders, academic performance, and economic self-sufficiency. The results will be compared to normative data by one-sample t-tests. Multivariable regression analysis will be used to assess for any associations with causative pathogens and severity of BM. Participants that complete the questionnaires will be approached to provide a swab for buccal DNA and subsequent sequencing analyses. Logistic regression models will be used to predict sequelae. Discussion The unique follow-up duration of this cohort will enable us to gain insights into the possible very long-term adverse effects of childhood BM and how these might impact on quality of life. The investigation of host genetic factors will contribute to the development of prediction models which will serve as prognostic tools to identify children who are at high risk of adverse outcome after BM. Trial Registration Dutch Trial Register NTR-6891. Retrospectively registered 28 December 2017.

scholarly journals A cross-sectional audit of distress in patients undergoing adjuvant therapy or follow-up in central nervous system malignancies

2018 ◽  
Vol 6 (4) ◽  
pp. 305-310
Author(s):  
Vijay M Patil ◽  
Mridul Malhotra ◽  
Raees Tonse ◽  
Jayita Deodhar ◽  
Arun Chandrasekharan ◽  
...  
Keyword(s):  
Adjuvant Chemotherapy ◽  
Negative Impact ◽  
Distress Screening ◽  
Cross Sectional ◽  
Factors Affecting ◽  
Distress Score ◽  
High Distress ◽  
Cancer Network

Abstract Background Unaddressed high distress leads to noncompliance with treatment, negatively affects quality of life, and may also have a negative impact on the prognosis of cancer patients. Patients with brain tumors have higher levels of distress than the general population and hence we hypothesize that even routine visits during adjuvant treatment or follow-up are likely to be stressful. This analysis was performed to identify the incidence of distress and factors affecting it. Methods This was an audit of 84 consecutive patients seen in an adult neuro-medical oncology outpatient department who were either receiving adjuvant chemotherapy or were on follow-up. Distress screening with the National Comprehensive Cancer Network (NCCN) distress thermometer was performed. Patients in whom distress was scored as 4 or above were considered as having high distress. Descriptive statistics and logistic regression analysis were performed to identify factors affecting distress. Results The median age of the cohort was 40 years (interquartile range, 28.3 to 50 years). Actionable distress defined as a distress score of 4 or more was seen in 52 patients (61.9%, 95% CI 51.2% to 71.5%). Presence of physical deficit (odds ratio [OR] = 3.412, P = .020) and treatment under the private category (OR = 5.273, P = .003) had higher odds of having high distress. Conclusion A high proportion of brain tumor patients either on adjuvant chemotherapy or on follow-up have high distress levels that need to be addressed even during follow-up.

scholarly journals Long-Term Effects of Kasai Portoenterostomy for Biliary Atresia Treatment in Russia

Diagnostics ◽  
2020 ◽  
Vol 10 (9) ◽  
pp. 686
Author(s):  
Anna Degtyareva ◽  
Alexander Razumovskiy ◽  
Nadezhda Kulikova ◽  
Sergey Ratnikov ◽  
Elena Filippova ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Survival Rate ◽  
Biliary Atresia ◽  
Kasai Portoenterostomy ◽  
Critical Importance ◽  
Long Term Effects ◽  
Age Related

This prospective study enrolled 144 patients after surgical treatment of biliary atresia in early infancy. We analyzed the immediate effectiveness of the surgery and the age-related structure of complications in the up to 16-year follow-up. The immediate 2-year survival rate after the surgery constituted 49.5%. At the time of this writing, 17 of the patients had celebrated their 10th birthdays with good quality of life and no indications for transplantation of the liver. The obtained results underscore the critical importance of surgical correction of biliary atresia by Kasai surgery in the first 60 days of life and subsequent dynamic follow-up of patients for the purpose of the early detection and timely correction of possible complications.

scholarly journals Oncological and quality of life outcomes following extralevator versus standard abdominoperineal excision for rectal cancer

2017 ◽  
Vol 99 (5) ◽  
pp. 402-409 ◽  
Author(s):  
D Kamali ◽  
A Sharpe ◽  
A Musbahi ◽  
A Reddy
Keyword(s):  
Quality Of Life ◽  
Rectal Cancer ◽  
Abdominoperineal Excision ◽  
Long Term Effects ◽  
Recurrence Rates ◽  
Oncological Outcomes ◽  
Significant Difference

INTRODUCTION There is increasing and conflicting research debating the oncological benefits of extralevator abdominoperineal excision (ELAPE) compared with standard abdominoperineal excision (SAPE). However, there is very little in the literature on the long-term effects on patients’ wellbeing following the two procedures. The aim of this study was to determine the oncological outcomes and long-term quality of life (QoL) of patients at two hospitals having undergone ELAPE or SAPE. METHODS Consecutive patients with rectal cancer who underwent either ELAPE or SAPE between January 2009 and June 2015 at a single centre were analysed. Oncological outcomes were determined by histology and follow-up imaging. QoL data were obtained prospectively using the QLQ-C30 and QLQ-CR29 questionnaires. RESULTS A total of 48 patients (36 male, 12 female; 27 ELAPE, 21 SAPE) were reviewed. The mean age was 67.4 years and the median follow-up duration was 44 months (range: 6–79 months). Four patients (2 ELAPE, 2 SAPE) developed local recurrence. Rates of distant metastasis were similar (ELAPE: 11%, SAPE: 14%). There was no significant difference in mean global health status score (ELAPE: 77.3, SAPE: 65.3). Impotence was the most frequently reported problem (mean symptom scores of 89.7 and 78.8 for ELAPE and SAPE respectively). CONCLUSIONS This is the largest study with the longest follow-up period that compares QoL after ELAPE with that after SAPE. Although more radical in nature, ELAPE did not demonstrate any significant impact on QoL compared with SAPE. There was no significant difference in long-term oncological outcome between the groups. Impotence remains a significant problem for all patients and they should be well informed of this risk prior to surgery.

Long-Term Effects of Total Social Isolation Upon Behavior of Rhesus Monkeys

1966 ◽  
Vol 18 (2) ◽  
pp. 567-580 ◽  
Author(s):  
G. D. Mitchell ◽  
E. J. Raymond ◽  
G. C. Ruppenthal ◽  
H. F. Harlow
Keyword(s):  
Social Behavior ◽  
Social Isolation ◽  
Rhesus Monkeys ◽  
First Year ◽  
Long Term Effects ◽  
Negative Effects ◽  
Cross Sectional ◽  
Follow Up Study

8 isolate monkeys were compared in a follow-up study to 8 sophisticated controls in brief cross-sectional pairings with 12 stimulus strangers: 4 adults, 4 age-mates, and 4 juveniles. The isolates were characterized by infantile disturbance, less environmental orality, more fear, more aggression, less sex, less play, and bizarre ritualistic movements. 12-mo. isolates were fearful and nonaggressive but threatened many attacks. 6-mo. isolates were fearful and physically aggressive. The 12-mo. isolates demonstrated practically no positive social behavior. Conclusions are: (a) 6 mo. of social isolation during the first year has negative effects on social behavior up to puberty, (b) abnormal aggression appears in 3-yr.-old 6-mo. isolates, and (c) 12 mo. of isolation suppress or delay this aggression.

Sign in / Sign up

Export Citation Format

Share Document