scholarly journals Effect of Post-Stroke Motor Training on EEG Movement-Related Cortical Potentials

2020 ◽  
Author(s):  
Maryam Butt ◽  
Golshah Naghdy ◽  
Fazel Naghdy ◽  
Geoffrey Murray ◽  
Haiping Du
Keyword(s):  
Low Cost ◽  
Motor Training ◽  
Clinical Test ◽  
Kinematic Parameters ◽  
Eeg Signals ◽  
Hand Rehabilitation ◽  
Stroke Patients ◽  
Post Stroke ◽  
Group A ◽  
Group B

Abstract BackgroundRehabilitation of post-stroke patients with motor impairments promotes re-learning of lost motor functions through the brain neuroplasticity. Monitoring of electroencephalogram (EEG) signals has the potential to show neuroplasticity changes that take place during motor training.MethodsIn this study, an EEG-derived time-domain pattern namely movement-related cortical potential (MRCP) was deployed to assess the effect of motor training in seven post-stroke patients. Patients were divided into two groups; group A comprising four subjects with supratentorial lesions and group B consisting of three subjects with infratentorial lesions. Both groups participated in motor training with an AMADEO hand rehabilitation device. During pre and post-training periods, EEG signals at eight selected electrodes were recorded. In addition, hand-kinematic parameters, and clinical tests were measured at the beginning and the end of all training sessions.ResultsThe negative peak of the MRCP signals decreased at all electrodes and reached significance in seven of eight electrodes for group A after 12 training sessions, while it was decreased at all electrodes and reached significance in two of eight electrodes for group B after 24 sessions according to paired t-test (p < 0.05). Moreover, these MRCP changes correlated with improvements in kinematic parameters and clinical test results for both groups.ConclusionsThis study shows that robot-assisted training that improves clinical outcomes is associated with MRCP pattern changes. Subjects with infratentorial strokes improved slower clinically compared to subjects with supratentorial strokes. This was consistent with the longer rehabilitation required for this group of patients to produce significant changes in MRCP. The reduction of negative peaks of the MRCP signal indicates that neurological pathways are established and less cortical resources are needed for motor tasks. This study demonstrates the significance of EEG as a practical and low-cost tool in detecting patterns associated with brain neuroplasticity in the course of motor re-learning. Ethics ApprovalThe procedures performed in this study were approved by the University of Wollongong Ethics Committee (Ethics application number: 2014/400) on 03/07/2017.

Comparison of changes in cognitive functions of post-stroke patients with the computer-based cognitive intervention (PABLO system) and conventional cognitive intervention (Paper-Pencil method)

2021 ◽  
Vol 17 ◽  
Author(s):  
Sudhi Kulshrestha ◽  
Manju Agrawal ◽  
Ajai K Singh ◽  
Akash Ved
Keyword(s):  
Cognitive Impairment ◽  
Cognitive Functions ◽  
Research Work ◽  
Cognitive Intervention ◽  
Stroke Patients ◽  
Post Stroke ◽  
Group A ◽  
Computer Based ◽  
Attention Memory ◽  
Group B

Background: Cognitive functions are mental series of activities that allow us to carry out any activity. The most important cognitive functions are orientation, attention, memory, executive functions, language, and visuospatial skills. Cognitive impairment is a prevalent consequence of stroke. Prognosis of stroke recovery can be estimated through the severity of cognitive impairment. The objective of this research work was to compare the changes in cognitive functions of post-stroke patients with the computer-based cognitive intervention (CBCI) using PABLO system and conventional cognitive intervention (CCI) using paper-pencil method. Methods: Total 80 stroke patients with cognitive impairment were selected and divided into two groups. The Group A received intervention through PABLO System (CBCI) and the Group B received the cognitive intervention through Paper Pencil method (CCI). Pre and post-assessment of cognitive functions like verbal fluency, language, orientation and attention, memory, visuospatial and mini mental state examination for both the groups were done by Addenbrooke Cognitive Examination-Revised (ACE-R) scale. Result: After the intervention of 4 weeks, patients of both groups showed improvement in cognitive functions. However, the group A scored higher in comparison to group B. Conclusion: Data suggest that both the interventions will bring the changes in cognitive functions post-stroke patients but CBCI may be much more effective in improving cognitive functions of stroke patients.

scholarly journals Efficacy of motor therapy over sensorimotor therapy in upper limb functions of post stroke patients

Biomedicine ◽  
2021 ◽  
Vol 41 (1) ◽  
pp. 120-124
Author(s):  
V. Rajalaxmi ◽  
M. Tharunya ◽  
S.S. Subramanian ◽  
G. Vaishnavi ◽  
Chandra Kumar K ◽  
...  
Keyword(s):  
Upper Limb ◽  
Fine Motor ◽  
Stroke Patients ◽  
Mean Values ◽  
Post Stroke ◽  
Medical College ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Nine Hole Peg Test

Introduction and Aim:Strokeis one of the leading causes of death and disability in India. The incidence of stroke rapidly increases with age, doubling for each decade after 55.In the majority of patients the upper limb is severely impaired than lower limb. The aim of this study was to analyze the efficacy of motor therapy over sensorimotor therapy in upper limb functions of post stroke patients.   Materials and Methods: This was an experimental study, of pre-post type, that was conducted in the outpatient department of Physiotherapy at ACS Medical College and Hospital,chennai.30 samples were selected from 45 volunteers according to inclusion criteria and the study was conducted for Group A received sensorimotor therapy for one session/day for 6 days a week for 12 weeks. Group B received motor therapy for one session/day for 6 days a week for 12 weeks. Pre and post measurement were done using motor assessment scale, stroke upper limb capacity scale, action research arm test and nine-hole peg test.   Results: There was a significant difference in mean values of group A and B on comparison. Group A seems to be more effective than group B.   Conclusion: The study concludes that both motor therapy and sensorimotor therapy are beneficial in stroke rehabilitation, but sensorimotor therapy is more effective in improving the gross and fine motor skills of the upper limb of stroke patients.

Moxifloxacin Based Triple Therapy as Alternative to Standard Therapy in Helicobacter Pylori Eradication.

2020 ◽  
Vol 18 ◽  
Author(s):  
Mohammed Hussien Ahmed ◽  
Sherief Abd-Elsalam ◽  
Aya Mohammed Mahrous
Keyword(s):  
Helicobacter Pylori ◽  
Triple Therapy ◽  
Therapy Group ◽  
Low Cost ◽  
High Rate ◽  
Helicobacter Pylori Eradication ◽  
Treatment Regimens ◽  
Group A ◽  
H Pylori ◽  
Group B

Introduction: Helicobacter pylori eradication remains a problematic issue. We are in an urgent need for finding a treatment regimen that achieves eradication at a low cost and less side effect. Recent published results showing a high rate of resistance and with clarithromycin-based treatment regimens. The aim of the study was to compare moxifloxacin therapy and classic clarithromycin triple therapy in H. pylori eradication. Methods: This was a pilot study that enrolled 60 patients with helicobacter pylori associated gastritis. Diagnosis was done by assessment of H. pylori Ag in the stool. The patients were randomly assigned to receive either moxifloxacin based therapy (Group A), or clarithromycin based therapy (Group B) for two weeks. We stopped the treatment for another two weeks then reevaluation for cure was done. Results: 90 % of patients had negative H. pylori Ag in the stool after 2 weeks of stoppage of the treatment in group A versus 66.7 % in Group B. None of the patients in both groups had major side effects. Conclusion: Moxifloxacin-based therapy showed higher eradication power and less resistance when compared to clarithromycin triple therapy.

scholarly journals EFFICACY OF ROLLING BOARD PERTURBATION TRAINING ON BALANCE AMONG HEMIPARETIC STROKE PATIENTS - A COMPARATIVE STUDY

2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Dr. Senthil kumar ◽  
Dr. Franklin Shaju M.K m k ◽  
Dr. Vijaya Senthil Kumar kumar ◽  
Dr. A. velmurugan
Keyword(s):  
Public Health Problem ◽  
Berg Balance Scale ◽  
Major Public Health Problem ◽  
Stroke Patients ◽  
Perturbation Training ◽  
Before And After ◽  
Group A ◽  
Hemiparetic Stroke ◽  
Conventional Physiotherapy ◽  
Group B

Background of the study: Stroke is a major public health problem that ranks in the top four causes of death in most of the countries and is responsible for a large proportion of the burden of neurologic disorders. Patients with stroke have poor balance because they cannot control dynamically the size of the base of support or the location of the line of gravity. Perturbation training undergoes the maximal sway possible without losing his balance. Objective of the study: The objective of the study is to find the effects of rolling board perturbation training on balance among hemiparetic stroke patients. Methodology: Thirty clinically diagnosed hemiparetic stroke patients were selected based on the inclusion and exclusion criteria. They were randomly allocated into two groups (Group A and Group B) consists of 15 subjects each. Group A received conventional physiotherapy alone and group B received rolling board perturbation training along with conventional physiotherapy. Intervention lasted for 4 weeks, three days in a week and one hour per day. Balance was measured before and after 4 weeks of intervention by berg balance scale. Conclusion: Both conventional physiotherapy alone and rolling board perturbation training along with conventional physiotherapy significantly improved balance among hemiparetic stroke patients. When comparing both rolling board perturbation training along with conventional physiotherapy is more effective than conventional physiotherapy alone in improving balance among hemiparetic stroke patients.

EFFECT OF LOW LEVEL LASER THERAPY ON HEMIPLEGIC SHOULDER PAIN IN POST STROKE SUBJECTS

2021 ◽  
pp. 73-76
Author(s):  
Pappala kiran Prakash ◽  
Dommeti Sai Sushmitha ◽  
P.R.S Thulasi ◽  
Ganapathi Swamy
Keyword(s):  
Laser Therapy ◽  
Shoulder Pain ◽  
Upper Limb ◽  
Rehabilitation Programme ◽  
Low Level Laser Therapy ◽  
Post Stroke ◽  
Upper Limb Function ◽  
Level Laser ◽  
Group A ◽  
Group B

Shoulder pain is a common complication of a stroke which can impede participation in rehabilitation and has been associated with poor outcomes. Low Level LASER Therapy (LLLT) is one of the adjunct treatments of choice with exercise therapy for shoulder rehabilitation in Physiotherapy. The objective of this study was to investigate the effect of LLLT on Hemiplegic Shoulder Pain (HSP) in reducing shoulder pain and improving upper limb function in post Stroke subjects. Prospective study design. 68 subjects with mean age of 53 years having a clinical diagnosis of Stroke with HSP were randomly allocated into two groups. In Group-A (n=34) subjects were treated with LLLT and standardized Rehabilitation Programme, where as in Group-B (n=34) subjects were treated with standardized Rehabilitation Programme. Participants were given interventions twice a week for 8 weeks. The outcomes of this intervention were measured by SPADI for pain, disability and FMA-UE for function. Statistical analysis of the data revealed that within group comparison both groups showed signicant improvement in all parameters, where as in between groups comparison Group-A showed better improvement compared to the Group-B. After 8 weeks of interventions both Group-A and Group-B showed signicant improvement in reducing pain and improving upper limb function. However LLLT along with Standardized Rehabilitation Programme showed more improvement when compared to the Standardised Rehabilitation Programme alone. Thus this study concludes that LLLT is a useful adjunct in HSPalong with rehabilitation

Abstract TP52: Endovascular Therapy in Patients Over 80 Years of Age With Acute Ischemic Stroke

Stroke ◽  
2020 ◽  
Vol 51 (Suppl_1) ◽  
Author(s):  
Janhavi M Modak ◽  
Syed Daniyal Asad ◽  
Jussie Lima ◽  
Amre Nouh ◽  
Ilene Staff ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Symptom Onset ◽  
Time Window ◽  
Extended Time ◽  
Stroke Patients ◽  
Stroke Outcomes ◽  
Stroke Treatment ◽  
Group A ◽  
Group B

Introduction: Acute ischemic stroke treatment has undergone a paradigm shift, with patients being treated in the extended time window (6-24 hours post symptom onset). The purpose of this study is to assess outcomes in stroke patients above 80 years of age undergoing endovascular treatment (EVT) in the extended time window. Methods: Acute ischemic stroke patients presenting to Hartford Hospital between January 2017 to June 2019 were considered for the study. Stroke outcomes in patients above 80 years of age with anterior circulation ischemic strokes presenting in the extended time window (Group A, n=30) were compared to a younger cohort of patients below 80 years (Group B, n=31). Patients over 80 years treated in the traditional time window (within 6 hours of symptom onset) served as a second set of controls (Group C, n=40). Statistical analysis was performed with a significance level of 0.05 Results: For angiographic results, there were no statistically significant differences in terms of good outcomes (TICI 2b-3) among patients of Group A, when compared to Groups B or C (p>0.05). For the endovascular procedures, no significant differences were noted in the total fluoroscopy time (Median Group A 44.05, Group B 38.1, Group C 35.25 min), total intra-procedure time (Median Group A 144, Group B 143, Group C 126 min) or total radiation exposure (Median Group A 8308, Group B 8960, Group C 8318 uGy-m 2 ). For stroke outcomes, a good clinical outcome was defined as modified Rankin score of 0-2 at discharge. Significantly better outcomes were noted in the younger patients in Group B - 35.4%, when compared to 13.3% in Group A (p=0.03). Comparative outcomes differed in the elderly patients above 80 years, Group A -13.3% vs Group C - 25%, although not statistically significant (p=0.23). There was a significant difference in mortality in patients of Group A - 40% as compared to 12% in the younger cohort, Group B (p= 0.01). Conclusions: In the extended time window, patients above 80 years of age were noted to have a higher mortality, morbidity compared to the younger cohort of patients. No significant differences were noted in the stroke outcomes in patients above 80 years of age when comparing the traditional and the extended time window for stroke treatment.

scholarly journals COMPARISON OF RESPONSE TO TREATMENT OF OTOMYCOSIS USING TOPICAL BETADINE AND CLOTRIMAZOLE DROPS

2019 ◽  
pp. 1-2
Author(s):  
Rajendra K. Teharia
Keyword(s):  
Developing Countries ◽  
Fungal Infection ◽  
External Auditory Canal ◽  
Povidone Iodine ◽  
Low Cost ◽  
Response To Treatment ◽  
Group A ◽  
Study Support ◽  
Group B ◽  
Nose And Throat

INTRODUCTION: Otomycosis is the fungal infection of EAC (External Auditory Canal) that is very commonly seen in Ear , Nose and Throat clinics .Local debridement and antifungals , topical or systemic is the treatment of choice but recurrences are very common and resistant to treatment. METHODS:Total 220 patients, divided into two groups each 110 in 'A' and 'B' were subjected to betadine (povidone - iodine )10% solution and Clotrimazole (1 %) drops treatment and response of treatment assessed on 5th , 10th and 20th day and analyzed. RESULTS :Out of 110 patients in each group on 5th day 21.8 % patients in group 'A', and 23.6 % in group B' showed no response. 70.9 % in group 'A' and 72.7 % in group 'B' were showed good response at evaluation of 20th day of treatment. CONCLUSION :In our study, betadine (10% solution) and Clotrimazole (1 %) drops were equally effective in treatment of otomycosis. Betadine(10% solution) is low cost, non-ototoxic, nonresistant and equally effective in bacterial and fungal infection. That's why this study support betadine 10% solution as treatment of choice for otomycosis specially in developing countries .

scholarly journals Hemispheric Coherence Analysis of Wide Band EEG Signals for Characterization of Post-Stroke Patients with Dementia

2021 ◽  
Vol 38 (4) ◽  
pp. 985-992
Author(s):  
Sugondo Hadiyoso ◽  
Hasballah Zakaria ◽  
Paulus Anam Ong ◽  
Tati Latifah E.R. Mengko
Keyword(s):  
Quantitative Analysis ◽  
Wide Band ◽  
P Value ◽  
Coherence Analysis ◽  
Stroke Survivors ◽  
Eeg Signals ◽  
Stroke Patients ◽  
Post Stroke ◽  
Significant Difference

Post-stroke dementia (PSD) is a type of vascular dementia (VaD) that might be occurred in post-stroke patients. Memory, language and behavior tests can be used for the analysis of cognitive impairment caused by PSD. Often a supporting clinical examination such as an electroencephalogram (EEG) is used to support the diagnosis or analyze the characteristic changes that occur in the brain. Conventional analysis or visual inspection of EEG signals can be very difficult, since the nature of the signal tends to be non-stationer. Therefore, this study proposes a quantitative analysis for the characterization of EEG signals in stroke survivors with dementia. It is thought that it has different characteristics with the normal subject so that this study can be used as a reference in supporting dementia detection in post-stroke survivors. The quantitative analysis used in this study is coherence analysis. Coherence analysis was performed on EEG signals recorded from six poststroke patients with dementia and then compared with ten normal healthy subjects. Analysis of coherence between brain areas includes inter and intra-hemispheric coherence. Validation was carried out by using the independent t-test where the confidence level was 95%, indicating that the p-value <0.05 had a significant difference. The test results show that in general the coherence of the electrode pairs in patients with dementia is lower than in the normal healthy group. It is notably, i) In interhemispheric, the C3-C4, T3-T4, and T5-T6 pairs generate significant differences, ii) the highest decrease in intrahemispheric coherence was found in C3-T5 with p = 0.0005. The coherence study presented in this paper is expected to be used for early detection of PSD in the future.

scholarly journals EFFICACY OF TENS WITH CONVENTIONAL OCCUPATIONAL THERAPY IN IMPROVING HAND FUNCTION OF STROKE SURVIVORS

2019 ◽  
Vol 8 (1) ◽  
pp. 25-30
Author(s):  
Faiza Tahir ◽  
Quratulain Khan
Keyword(s):  
Occupational Therapy ◽  
Conventional Therapy ◽  
Controlled Trial ◽  
Hand Function ◽  
Low Frequency ◽  
Optimal Recovery ◽  
Stroke Survivors ◽  
Stroke Patients ◽  
Group A ◽  
Group B

BACKGROUND AND AIM Stroke is currently the second leading cause of death and third main cause of disability throughout the world. Around 75% of stroke survivors suffered from upper limb dysfunction with limited functional activities whereas distal parts of upper extremity such as hand and forearm are mostly affected by stroke. Therefore, this study aims to determine the benefits of TENS along with conventional Occupational therapy in the rehabilitation of stroke patients to ascertain the optimal recovery of hand function. METHODOLOGY A Single-blind Randomized Controlled Trial was conducted on 76 individuals with acute phase or one-year history post-stroke. Group-A (n=38) received Low Frequency Transcutaneous Electrical Nerve Stimulation on elbow and wrist extensors (3 Hz, 400 μs)along with conventional Occupational therapy while Group-B (n=38) received conventional Occupational therapy only. Both the groups received intervention for 5 days/week of duration 45 minutes till 3 weeks. RESULTS Group-A showed significant improvement in means scores of FMA-UE and ARAT (p<0.05) in comparison to Group-B which showed moderate improvements in sensorimotor and activity capacity of hand function. CONCLUSION Conventional therapy along with TENS significantly improved the hand function in acute stroke patients as compared to the conventional therapy.

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