scholarly journals Spatiotemporal Beam Self-cleaning for High-resolution Nonlinear Fluorescence Imaging With Multimode Fiber

Author(s):  
Nawell OULD-MOUSSA ◽  
Tigran Mansuryan ◽  
Charles-Henri Hage ◽  
Marc Fabert ◽  
Katarzyna Krupa ◽  
...  

Abstract Beam self-cleaning (BSC) in graded-index (GRIN) multimode fibers (MMFs) has been recently reported by different research groups. Driven by the interplay between Kerr effect and beam self-imaging, BSC counteracts random mode coupling, and forces laser beams to recover a quasi-single mode profile at the output of GRIN fibers. Here we show that the associated self-induced spatiotemporal reshaping allows for improving the performances of nonlinear fluorescence (NF) microscopy and endoscopy using multimode optical fibers. We experimentally demonstrate that the beam brightness increase, induced by self-cleaning, enables two and three-photon imaging of biological samples with high spatial resolution. Temporal pulse shortening accompanying spatial beam clean-up enhances the output peak power, hence the efficiency of nonlinear imaging. We also show that spatiotemporal supercontinuum (SC) generation is well-suited for large-band NF imaging in visible and infrared domains. We substantiated our findings by multiphoton fluorescence imaging in both microscopy and endoscopy configurations.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Nawell Ould Moussa ◽  
Tigran Mansuryan ◽  
Charles-Henri Hage ◽  
Marc Fabert ◽  
Katarzyna Krupa ◽  
...  

AbstractBeam self-cleaning (BSC) in graded-index (GRIN) multimode fibers (MMFs) has been recently reported by different research groups. Driven by the interplay between Kerr effect and beam self-imaging, BSC counteracts random mode coupling, and forces laser beams to recover a quasi-single mode profile at the output of GRIN fibers. Here we show that the associated self-induced spatiotemporal reshaping allows for improving the performances of nonlinear fluorescence (NF) microscopy and endoscopy using multimode optical fibers. We experimentally demonstrate that the beam brightness increase, induced by self-cleaning, enables two and three-photon imaging of biological samples with high spatial resolution. Temporal pulse shortening accompanying spatial beam clean-up enhances the output peak power, hence the efficiency of nonlinear imaging. We also show that spatiotemporal supercontinuum (SC) generation is well-suited for large-band NF imaging in visible and infrared domains. We substantiated our findings by multiphoton fluorescence imaging in both microscopy and endoscopy configurations.


2020 ◽  
Author(s):  
Nawell Ould-Moussa ◽  
Tigran Mansuryan ◽  
Charles-Henri Hage ◽  
Marc Fabert ◽  
Katarzyna Krupa ◽  
...  

Abstract Beam self-cleaning (BSC) in graded-index (GRIN) multimode fibres (MMFs) has been recently reported by different research groups. Driven by the interplay between Kerr effect and beam self-imaging, BSC counteracts random mode coupling, and forces laser beams to recover a quasi-single mode profile at the output of GRIN fibres. Here we show that the associated self-induced spatiotemporal reshaping allows for improving the performances of nonlinear fluorescence microscopy and endoscopy using multimode optical fibres. We experimentally demonstrate that the beam brightness increase, induced by self-cleaning, enables two and three-photon imaging of biological samples with high spatial resolution. Temporal pulse shortening accompanying spatial beam clean-up enhances the output peak power, hence the efficiency of nonlinear imaging. We also show that spatiotemporal supercontinuum generation is well-suited for large-band nonlinear fluorescence imaging in visible and infrared domains. We substantiated our findings by multiphoton fluorescence imaging in both microscopy and endoscopy configurations.


Photonics ◽  
2021 ◽  
Vol 8 (9) ◽  
pp. 354
Author(s):  
Leila Graini ◽  
Bülend Ortaç

This paper aims to pave the way towards the demonstration of spatiotemporal similariton pulses’ evolution in passive multimode fibers with Raman amplification. We numerically present this issue in graded-index and step-index multimode fibers and provide a first look at the complex spatiotemporal dynamics of similariton pulses. The results showed that the similariton pulses could be generated in both multimode fibers. The temporal and spectral evolution of the pulses can be characterized as parabolic shapes with linear chirp and kW peak power. By compressing these, high-energy femtoseconds pulses can be obtained, starting initial picosecond pulses. A spatial beam profile could be preserved in both multimode fibers with the most energy coupled to the fundamental mode. Specifically, the similariton pulses’ generation with Raman amplification in a graded-index multimode fiber improves the spatial beam self-cleaning process under the different initial modes’ excitation. The observation of a new beam self-cleaning process is another attractor feature of propagation in graded-index multimode fibers.


1992 ◽  
Vol 247 ◽  
Author(s):  
Yasuhiro Koike

ABSTRACTHigh-bandwidth graded-index (GI) polymer optical fiber (POF) and single-mode POF with good mechanical properties were successfully obtained by our interfacial-gel polymerization technique. The bandwidth of the GI POF is about 1 GHz · km which is two hundred times larger than that of the conventional step-index (SI) POF. The minimum attenuation of transmission is 56 dB/km at 688-nm wavelength and 94 dB/km at 780-nm wavelength. The single-mode POF in which the core diameter was 3–15 μ m and the attenuation of transmission was 200 dB/km at 652-nm wavelength was successfully obtained for the first time.


1970 ◽  
Vol 4 (2) ◽  
Author(s):  
Mostafa H. Ali, Ahmed E. Elsamahy, Maher A. Farhoud and Taymour A. Hamdalla

Near field distribution, propagation constant and dispersion characteristics of nonlinear single-mode optical fibers have been investigated. Shooting-method technique is used and implemented into a computer code for both profiles of step-index and graded-index fibers. An error function is defined to estimate the discrepancy between the expected electric-field radial derivative at the core-cladding interface and that obtained by numerically integrating the wave equation through the use of Runge-Kutta method. All of the above calculations done under the ocean depth in which the depth will affect the refractive index that have a direct effect on all the optical fiber parameters.KeyWords: Nonlinear refractive index, Normalized propagation constant, Mode delay factor, Material dispersion, Waveguide dispersion.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Zahra Mohammadzahery ◽  
Maryam Jandaghi ◽  
Ebrahim Aghayari ◽  
Hasan Nabavi

AbstractIn this paper, we experimentally demonstrate that a nonlinear Kerr effect in suitable coupling conditions can introduce a spatially self-cleaned output beam for a few-mode step-index fiber. The impact of the distribution of the initial excited modes on spatial beam self-cleaning has been demonstrated. It is also shown experimentally that for specific initial conditions, the output spatial pattern of the pulsed laser can be reshaped into the LP11 mode due to nonlinear coupling among the propagating modes. Self-cleaning into LP11 mode required higher input powers with respect to the power threshold for LP01 mode self-cleaning. Our experimental results are in agreement with the results of numerical calculations.


IEEE Access ◽  
2021 ◽  
Vol 9 ◽  
pp. 46260-46264
Author(s):  
Jianan Dai ◽  
Weitao He ◽  
Qichang Ma ◽  
Ai-Ping Luo ◽  
Weiyi Hong

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