scholarly journals Supplementation with Human-Origin Probiotic Lactobacillus plantarum PL-02 Could Effectively Improve Muscle Mass and Exercise Performance, and Have an Anti-Fatigue Effect

2021 ◽  
Author(s):  
Mon-Chien Lee ◽  
Yi-Ju Hsu ◽  
Hsieh‐Hsun Ho ◽  
Yi‐Wei Kuo ◽  
Wen-Yang Lin ◽  
...  
Keyword(s):  
Body Composition ◽  
Gut Microbiota ◽  
Lactobacillus Plantarum ◽  
Muscle Mass ◽  
Exercise Performance ◽  
Biochemical Parameters ◽  
Endurance Performance ◽  
Glycogen Storage ◽  
Human Origin ◽  
Fatigue Effect

Abstract Gut microbiota are very important for energy metabolism and regulation, which in turn affect the health and physiological functions of the host. The most direct way to change the gut microbiota is to supplement with probiotics. In this study, we screened Lactobacillus plantarum (PL-02), a probiotic of human-origin, from the intestines of Olympic gold medalists and explored the role of PL-02 in improved exercise endurance performance, reduced fatigue biochemical parameters, and changes in body composition. Male Institute of Cancer Research (ICR) mice were assigned to 0 CFU/kg (vehicle), 2.05 × 109 CFU/kg (PL-02-1X), 4.10 × 109 CFU/kg (PL-02-2X), and 1.03 × 1010 CFU/kg (PL-02-5X) groups and were fed by oral gavage once daily for 4 weeks to assess exercise performance, fatigue parameters, and body composition. The results showed that 4 weeks of PL-02 supplementation could significantly increase muscle mass, improve muscle strength and endurance performance, and increase hepatic and muscular glycogen storage. Furthermore, PL-02 could significantly decrease fatigue biochemical parameters, such as lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels, after exercise. We believe that PL-02 can be used as a supplement to improve exercise performance and for its anti-fatigue effect.

scholarly journals Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Mon-Chien Lee ◽  
Yi-Ju Hsu ◽  
Hsieh‐Hsun Ho ◽  
Yi‐Wei Kuo ◽  
Wen-Yang Lin ◽  
...  
Keyword(s):  
Gut Microbiota ◽  
Lactobacillus Plantarum ◽  
Muscle Mass ◽  
Exercise Performance ◽  
Endurance Performance ◽  
Glycogen Storage ◽  
Human Origin ◽  
Gold Medalist ◽  
Improve Exercise Performance

AbstractGut microbiota is very important for energy metabolism and regulation, which in turn affect the health and physiological functions of the host, and provide energy required for exercise. Supplementation with probiotics may be one of the ways to change the gut microbiota. In recent years, many studies have shown that probiotic supplementation can effectively improve sports performance. In this study, we screened Lactobacillus plantarum (PL-02), a probiotic of human-origin, from the intestines of 2008 Olympic women's 48 kg weightlifting gold medalist and explored the role of PL-02 in improved exercise endurance performance, reduced fatigue biochemical parameters, and changes in body composition. Male Institute of Cancer Research (ICR) mice were assigned to 0, 2.05 × 109, 4.10 × 109 and 1.03 × 1010 CFU/kg/day groups and were fed by oral gavage once daily for 4 weeks. The results showed that 4 weeks of PL-02 supplementation could significantly increase muscle mass, muscle strength and endurance performance, and hepatic and muscular glycogen storage. Furthermore, PL-02 could significantly decrease lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels after exercise (p < 0.05). We believe that PL-02 can be used as a supplement to improve exercise performance and for its anti-fatigue effect.

scholarly journals Effect of Lactobacillus plantarum TWK10 on Exercise Physiological Adaptation, Performance, and Body Composition in Healthy Humans

Nutrients ◽  
2019 ◽  
Vol 11 (11) ◽  
pp. 2836 ◽  
Author(s):  
Wen-Ching Huang ◽  
Mon-Chien Lee ◽  
Chia-Chia Lee ◽  
Ker-Sin Ng ◽  
Yi-Ju Hsu ◽  
...  
Keyword(s):  
Body Composition ◽  
Lactobacillus Plantarum ◽  
Athletic Training ◽  
Exercise Performance ◽  
Exercise Physiology ◽  
Physiological Adaptation ◽  
High Dose ◽  
Dependent Manner ◽  
Double Blind ◽  
Healthy Humans

Probiotics have been rapidly developed for health promotion, but clinical validation of the effects on exercise physiology has been limited. In a previous study, Lactobacillus plantarum TWK10 (TWK10), isolated from Taiwanese pickled cabbage as a probiotic, was demonstrated to improve exercise performance in an animal model. Thus, in the current study, we attempted to further validate the physiological function and benefits through clinical trials for the purpose of translational research. The study was designed as a double-blind placebo-controlled experiment. A total of 54 healthy participants (27 men and 27 women) aged 20–30 years without professional athletic training were enrolled and randomly allocated to the placebo, low (3 × 1010 colony forming units (CFU)), and high dose (9 × 1010 CFU) TWK10 administration groups (n = 18 per group, with equal sexes). The functional and physiological assessments were conducted by exhaustive treadmill exercise measurements (85% VO2max), and related biochemical indices were measured before and after six weeks of administration. Fatigue-associated indices, including lactic acid, blood ammonia, blood glucose, and creatinine kinase, were continuously monitored during 30 min of exercise and a 90 min rest period using fixed intensity exercise challenges (60% VO2max) to understand the physiological adaptation. The systemic inflammation and body compositions were also acquired and analyzed during the experimental process. The results showed that TWK10 significantly elevated the exercise performance in a dose-dependent manner and improved the fatigue-associated features correlated with better physiological adaptation. The change in body composition shifted in the healthy direction for TWK10 administration groups, especially for the high TWK10 dose group, which showed that body fat significantly decreased and muscle mass significantly increased. Taken together, our results suggest that TWK10 has the potential to be an ergogenic aid to improve aerobic endurance performance via physiological adaptation effects.

scholarly journals Lactobacillus salivarius Subspecies salicinius SA-03 is a New Probiotic Capable of Enhancing Exercise Performance and Decreasing Fatigue

2020 ◽  
Vol 8 (4) ◽  
pp. 545 ◽  
Author(s):  
Mon-Chien Lee ◽  
Yi-Ju Hsu ◽  
Hsieh-Hsun Ho ◽  
Shih-Hung Hsieh ◽  
Yi-Wei Kuo ◽  
...  
Keyword(s):  
Exercise Performance ◽  
Endurance Performance ◽  
Nutritional Supplement ◽  
Glycogen Storage ◽  
Lactobacillus Salivarius ◽  
Post Exercise ◽  
Beneficial Effects ◽  
Natural Flora ◽  
Improve Exercise Performance ◽  
Exercise Fatigue

Probiotics are increasingly being used as a nutritional supplement by athletes to improve exercise performance and reduce post-exercise fatigue. Lactobacillus salivarius is a natural flora in the gastrointestinal tract of humans and animals. Lactobacillus salivarius subspecies salicinius (SA-03) is an isolate from the 2008 Olympic women’s 48 kg weightlifting gold medalist’s gut microbiota. In this study, we investigated its beneficial effects on physical fitness. Male ICR mice were divided into four groups (n = 10 per group) and orally administered with SA-03 for 4 weeks at 0, 2.05 × 109, 4.10 × 109, or 1.03 × 1010 CFU/kg/day. Results showed that 4 weeks of SA-03 supplementation significantly improved muscle strength and endurance performance, increased hepatic and muscular glycogen storage, and decreased lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels after exercise. These observations suggest that SA-03 could be used as a nutritional supplement to enhance exercise performance and reduce.

scholarly journals Isolated Soy Protein Supplementation and Exercise Improve Fatigue-Related Biomarker Levels and Bone Strength in Ovariectomized Mice

Nutrients ◽  
2018 ◽  
Vol 10 (11) ◽  
pp. 1792 ◽  
Author(s):  
Che-Li Lin ◽  
Mon-Chien Lee ◽  
Yi-Ju Hsu ◽  
Wen-Ching Huang ◽  
Chi-Chang Huang ◽  
...  
Keyword(s):  
Body Composition ◽  
Exercise Training ◽  
Muscle Mass ◽  
Bone Strength ◽  
Soy Protein ◽  
Exercise Performance ◽  
Protein Supplementation ◽  
The Body ◽  
Ovariectomized Mice ◽  
Isolated Soy Protein

Isolated soy protein (ISP) is a well-known supplement and has been reported to improve health, exercise performance, body composition, and energy utilization. ISP exhibits multifunctional bioactivities and also contains branched-chain amino acids (BCAAs), which have been confirmed to positively affect body weight (BW) regulation and muscle protein synthesis. The combined effects of BCAA supplements and exercise in older postmenopausal women with osteoporosis, sarcopenia, and obesity have been inadequately investigated. Therefore, in this study, we evaluated the potential beneficial effects of soy protein supplementation and exercise training on postmenopausal mice. Forty mice (14 weeks old) with ovariectomy-induced osteosarcopenic obesity were divided into five groups (n = 8), namely sham ovariectomy (OVX, control), OVX, OVX with ISP supplementation (OVX+ISP), OVX with exercise training (ET, OVX+ET), and OVX with ISP and ET (OVX+ISP+ET). The mice received a vehicle or soy protein (3.8 g/kg BW) by oral gavage for four weeks, and the exercise performance (forelimb grip strength and exhaustive swimming time) was evaluated. In the biochemical profiles, we evaluated the serum glucose level and tissue damage markers, such as lactate, ammonia, glucose, blood urine nitrogen (BUN), and creatinine phosphate kinase (CPK). The body composition was determined by evaluating bone stiffness and muscle mass. All data were analyzed using one-way repeated measures analysis of variance. The physical performance of the OVX+ISP+ET group did not differ from that of the other groups. The OVX+ISP+ET group exhibited lower levels of serum lactate, ammonia, CPK, and BUN as well as economized glucose metabolism after an acute exercise challenge. The OVX+ISP+ET group also exhibited higher muscle mass and bone strength than the OVX group. Our study demonstrated that a combination of ISP supplementation and exercise reduced fatigue and improved bone function in OVX mice.

scholarly journals Efficacy of Dietary Interventions on Weight Loss and Biochemical Parameters Among Saudi Females with Obesity and Overweight: An Interventional Non-Randomized Control Trail.

2020 ◽  
Author(s):  
Dara Aldisi ◽  
Tayyaba Afsar ◽  
Amani Abdullah Al-farraj ◽  
Alaa Fahad Alothman ◽  
Shajan Hassan Al-Mokyel ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Muscle Mass ◽  
Biochemical Parameters ◽  
Dietary Interventions ◽  
Balanced Diet ◽  
Obesity And Overweight ◽  
Weight Loss Method ◽  
Ideal Protein ◽  
Loss Method

Abstract Background: Numerous dietary approaches have been proposed to treat obesity. We investigated the efficacy of the Ideal Protein Weight Loss Method (IPWLM) diet and the balanced diet (BD) on anthropometric, body composition, and biochemical parameters in obese/overweight subjects. Methods: 60 overweight/obese females from Riyadh, Saudi Arabia were divided into two groups: Group IPWLM (n=29) followed the IPWLM diet, while the BD group (n=31) received a balanced diet for 6 weeks. Result: Significant reduction in anthropometric measurements and body composition were observed in BD and IPWLM groups. In both BD and IPWLM groups, all weight, % body fat (BF), % muscle mass, hip and waist circumferences, and body mass index (BMI) had a significant reduction (p, for all trends <0.05). BD group subjects had a significant reduction in triglycerides (TG) and cholesterol (p <0.05), while no changes in HDL and glucose (p, for all trends >0.05). IPWLM group showed no significant effects on blood glucose and lipid profile (LDL, HDL, and cholesterol (p >0.05). Conclusion: Although the IPWLM diet did not improve biochemical parameters, it was significantly associated with improvements in anthropometrics, %BF, and muscle mass preservation. On the other hand, BD was more favorable in anthropometrics, body composition as well as biochemical parameters.

scholarly journals Lactobacillus plantarum TWK10 Supplementation Improves Exercise Performance and Increases Muscle Mass in Mice

Nutrients ◽  
2016 ◽  
Vol 8 (4) ◽  
pp. 205 ◽  
Author(s):  
Yi-Ming Chen ◽  
Li Wei ◽  
Yen-Shuo Chiu ◽  
Yi-Ju Hsu ◽  
Tsung-Yu Tsai ◽  
...  
Keyword(s):  
Lactobacillus Plantarum ◽  
Muscle Mass ◽  
Exercise Performance

scholarly journals Lactobacillus plantarum PS128 Improves Physiological Adaptation and Performance in Triathletes through Gut Microbiota Modulation

Nutrients ◽  
2020 ◽  
Vol 12 (8) ◽  
pp. 2315 ◽  
Author(s):  
Wen-Ching Huang ◽  
Chun-Hsu Pan ◽  
Chen-Chan Wei ◽  
Hui-Yu Huang
Keyword(s):  
Lactobacillus Plantarum ◽  
Exercise Performance ◽  
Maximal Oxygen Consumption ◽  
Endurance Performance ◽  
Short Chain Fatty Acids ◽  
Physiological Adaptation ◽  
Endurance Running ◽  
Supplement Group ◽  
Significant Difference ◽  
And Performance

A triathlon is an extremely high-intensity exercise and a challenge for physiological adaptation. A triathlete’s microbiome might be modulated by diet, age, medical treatments, lifestyle, and exercise, thereby maintaining aerobiosis and optimum health and performance. Probiotics, prebiotics, and synbiotics have been reported to have health-promoting activities (e.g., immunoregulation and cancer prevention). However, few studies have addressed how probiotics affect the microbiota of athletes and how this translates into functional activities. In our previous study, we found that Lactobacillus plantarum PS128 could ameliorate inflammation and oxidative stress, with improved exercise performance. Thus, here we investigate how the microbiota of triathletes are altered by L. plantarum PS128 supplementation, not only for exercise performance but also for possible physiological adaptation. The triathletes were assigned to two groups: an L. plantarum 128 supplement group (LG, 3 × 1010 colony-forming units (CFU)/day) and a placebo group (PG). Both groups continued with their regular exercise training for the next 4 weeks. The endurance performance, body composition, biochemistries, blood cells, microbiota, and associated metabolites were further investigated. PS128 significantly increased the athletes’ endurance, by about 130% as compared to the PG group, but there was no significant difference in maximal oxygen consumption (VO2max) and composition between groups. The PS128 supplementation (LG) modulated the athlete’s microbiota with both significant decreases (Anaerotruncus, Caproiciproducens, Coprobacillus, Desulfovibrio, Dielma, Family_XIII, Holdemania, and Oxalobacter) and increases (Akkermansia, Bifidobacterium, Butyricimonas, and Lactobacillus), and the LG showed lower diversity when compared to the PG. Also, the short-chain fatty acids (SCFAs; acetate, propionate, and butyrate) of the LG were significantly higher than the PG, which might be a result of a modulation of the associated microbiota. In conclusion, PS128 supplementation was associated with an improvement on endurance running performance through microbiota modulation and related metabolites, but not in maximal oxygen uptake.

scholarly journals A Preliminary Study of Pre-Season Taekwondo Preparation Strategy: Personal Isolation Training Effect for Elite Athletes

2021 ◽  
Vol 18 (20) ◽  
pp. 10570
Author(s):  
Yu-Chi Sung ◽  
Yi-Zhen Yang ◽  
Che-Chia Chang ◽  
Chun-Chung Chou
Keyword(s):  
Body Composition ◽  
Reaction Time ◽  
Muscle Mass ◽  
Aerobic Capacity ◽  
Endurance Performance ◽  
Training Group ◽  
Training Model ◽  
Trunk Muscle ◽  
Sprint Performance ◽  
Jump Performance

Background: The global coronavirus disease pandemic (COVID-19) has had a considerable impact on athletic competition and team sports training. Athletes have been forced to train alone at home. However, the isolation training model effects are still unknown. Purpose: This study compared the effects of personal isolation training (PIT) and detraining (DT) on specific sport performances (flexibility, power, reaction time, acceleration, and aerobic capacity) and body composition in elite taekwondo athletes. Methods: Eleven elite taekwondo athletes were recruited as voluntary subjects. Athletes were randomly paired by weight into the personal isolation training group (PIT group: N = 5, age: 21.2 ± 0.4 years, BMI: 22.2 ± 0.8 kg/m2) or detraining group (DT group: N = 6, age: 19.8 ± 0.3 years, BMI: 23.1 ± 1.0 kg/m2). All subjects performed the same training content prior to the pre-test (T1). When the pre-test was completed, all subjects underwent 12 weeks of PIT or DT. Athletes were then administrated the post-test (T2). The athlete’s sport performances and body composition were measured to compare the differences between the two groups (PIT and DT) and two phases (T1 and T2). Results: There were no significant differences in kicking reaction time and flexibility in both groups (p > 0.05). The PIT showed significant improvements in 10 m (10M) sprint performance (p < 0.05), and displayed a progress trend in Abalakov jump performance. In addition, the PIT resulted in a better change response in 10M sprint performance (PIT: −4.2%, DT: +2.1%), aerobic endurance performance (PIT: −10.2%, DT: −18.4%), right arm muscle mass (PIT: +2.9%, DT: −3.8%), and trunk muscle mass (PIT: +2.2%, DT: −1.9%) than DT (p < 0.05). The fat mass percentage showed a negative change from T1 to T2 in both groups (p < 0.05). Conclusions: PIT showed a trend toward better body composition (arm and trunk muscle) and sport performances (10M sprint and aerobic capacity) compared to DT. This finding may provide information on the effectiveness of a personal isolation training model for optimal preparation for taekwondo athletes and coaches. It may also serve as a useful and safe guideline for training recommendations during the coronavirus disease (COVID-19).

scholarly journals Ergogenic Effects of Green Tea Combined with Isolated Soy Protein on Increasing Muscle Mass and Exercise Performance in Resistance-Trained Mice

Nutrients ◽  
2021 ◽  
Vol 13 (12) ◽  
pp. 4547
Author(s):  
Mon-Chien Lee ◽  
Yi-Ju Hsu ◽  
Li-Hsuan Yang ◽  
Chi-Chang Huang ◽  
Chun-Sheng Ho
Keyword(s):  
Resistance Training ◽  
Muscle Mass ◽  
Green Tea ◽  
Soy Protein ◽  
Exercise Performance ◽  
Biochemical Parameters ◽  
Training Group ◽  
Swimming Time ◽  
Increase Muscle Mass ◽  
Isolated Soy Protein

It is well known that supplementation with high protein after exercise can effectively promote muscle synthesis and repair, while green tea is rich in catechins that have antioxidant effects. We aimed to explore the effects of green tea combined with isolated soy protein on increase muscle mass in resistance-trained mice. A total of 32 male ICR mice (8-weeks old) were divided into four groups (n = 8/group), sedentary control group (SC), isolated soy protein with green tea group (ISPG), resistance training group (RT), isolated soy protein and green tea combine with resistance training group (ISPG + RT). All mice received control or ISPG by oral gavage for four consecutive weeks. Forelimb grip and exhaustive swimming time were used for exercise performance evaluation. In biochemical profile, we analyzed lactate, ammonia, blood urea nitrogen (BUN), and glucose and muscle damage index creatine kinase (CK) after exercise as biochemical parameters of exercise fatigue. The grip strength, muscular endurance, and exhaustive swimming time of the ISPG + RT group were significantly increased than other groups (p < 0.05), and also significantly decreased in serum lactate and ammonia levels (p < 0.05, respectively). The ISP + RT group was not only increased in quadriceps weight, (p < 0.05) but also decreased EFP (p < 0.05). We recommend using a 4-week supplementation with ISPG, combined with RT, to increase muscle mass, exercise performance, glycogen storage, and reduce fatigue biochemical parameters after exercise. The benefits of long-term supplementation or application to human supplementation can be further explored in the future.

Effects of Consumption of Probiotic Powder Containing Lactobacillus Plantarum Dad-13 on Fecal Bacterial Population in School-Age Children in Indonesia

2019 ◽  
Vol 14 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Banin Maghfirotin Marta ◽  
Utami Tyas ◽  
Cahyanto Muhammad Nur ◽  
Widada Jaka ◽  
Rahayu Endang Sutriswati
Keyword(s):  
Placebo Group ◽  
Gut Microbiota ◽  
Lactobacillus Plantarum ◽  
Coliform Bacteria ◽  
School Age Children ◽  
Controlled Study ◽  
School Age ◽  
Double Blind ◽  
Probiotic Group ◽  
E Coli

Consumption of probiotics is known to influence the gut microbiota. The aim of this study was to assess the effect of probiotic powder containing Lactobacillus plantarum Dad-13 on bacterial composition in the gut by examining fecal samples of school-age children in Yogyakarta, Indonesia. This is a randomized, double-blind, placebo-controlled study. A total of 40 healthy subjects were recruited for this study and were divided into two groups: placebo group and probiotic group. The placebo group consumed skim milk and the probiotic group consumed probiotic powder containing L. plantarum Dad-13 (2 × 109 CFU/g) for 65 days. The results showed that placebo intake had no significant effect on gut microbiota; however, probiotic caused a significant increase in L. plantarum and Lactobacillus population, while decreasing the population of E. coli and non-E. coli coliform bacteria by 55% and 75%, respectively and Bifidobacteria count did not change significantly. The study concluded that consumption of probiotic powder L. plantarum Dad-13 could increase propionic acid thereby decreasing the gut pH which has an effect on the microbial population.

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