Circulating Omentin-1, Insulin Resistance and Lipid Profile Responses Following 8-weeks Aerobic Training Intervention Among Smokers Vs. Non-smokers

2020 ◽  
Author(s):  
Seyed Maysam Mousavi ◽  
Ali Heidarianpour ◽  
Hassan Tavassoli
Keyword(s):  
Insulin Resistance ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
Exercise Group ◽  
Normal Weight ◽  
Aerobic Exercise Training ◽  
Lipoprotein Cholesterol ◽  
Control Group

Abstract Background: Omentin-1 is a recently circulating adipokine that plays a crucial role in modulating insulin resistance and diabetes. We investigated the effect of eight weeks aerobic exercise training on serum omentin-1, insulin resistance and lipid profile in the smoker and non-smokers with normal-weight. Methods: Nineteen healthy men and twenty smoker men were randomly assigned into healthy control group (C), healthy exercise group (E), control smoker group (CS) and exercise smoker group (ES). Exercise groups participated in an 8-weeks aerobic exercise training program (three times a week, 45 min per session at 65%-80% of maximum heart rate). Serum omentin-1 and insulin values were determined by ELISA and HOMA-IR, glucose and lipid profile were measured at pre and post of the intervention. Paired Sample t-test, one-way analysis of variance (One-way ANOVA) and post-hoc Tukey test were applied to analyze the data (p<0.05).Results: Aerobic exercise improved both serum omentin-1 and high lipoprotein cholesterol (HDL-C) in the exercise groups (p<0.05). Also, Exercise training reduced insulin, blood sugar, HOMA-IR, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels (p<0.05). Omentin-1 were significantly associated with insulin (r=-0.40, P=0.01), HOMA-IR (r=-0.38, P=0.04), TG (r=-0.40, P=0.01), TC (r=-0.49, P=0.02), LDL-C (r=-0.70, P=0.02) and HDL-C (r=0.55, P=0.03).Conclusion: The findings suggest that aerobic exercise-induced changes in omentin-1 in exercise trained smokers may be associated with the beneficial effects of exercise on reduced insulin and lipid profile.

scholarly journals Circulating Omentin-1, Insulin Resistance and Lipid Profile Responses Following an Eight-week Aerobic Training Intervention Among Male Smokers 

2020 ◽  
Author(s):  
Seyed Maysam Mousavi ◽  
Ali Heidarianpour ◽  
Hassan Tavassoli
Keyword(s):  
Insulin Resistance ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
Normal Weight ◽  
Aerobic Exercise Training ◽  
Lipoprotein Cholesterol ◽  
Control Group ◽  
Model Assessment

Abstract Background: Omentin-1 is a recently discovered circulating adipokine that plays a crucial role in modulating insulin resistance and diabetes. We investigated the effect of eight weeks of aerobic exercise training on serum omentin-1, insulin resistance and lipid profile in the smokers and non-smokers with normal weight. Methods: Nineteen male healthy and twenty male smokers were randomly assigned into healthy control group (C), healthy exercise group (E), control smoker group (CS) and exercise smoker group (ES). Exercise groups participated in an eight-week aerobic exercise training program (three times a week, 20-35 min per session at 55%-70% of maximum heart rate). Serum omentin-1 and insulin values were determined by ELISA and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), glucose and lipid profile was measured before and after the intervention. Paired samples t-test, one-way analysis of variance (One-way ANOVA) and post-hoc Tukey test were applied to analyze the data (p<0.05).Results: Aerobic exercise improved both serum omentin-1 and high lipoprotein cholesterol (HDL-C) in the exercise groups (p<0.05). Also, Exercise training reduced insulin, blood sugar, HOMA-IR, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels (p<0.05). Omentin-1 was significantly correlated with insulin (r=-0.40, P=0.01), HOMA-IR (r=-0.38, P=0.04), TG (r=-0.40, P=0.01), TC (r=-0.49, P=0.02), LDL-C (r=-0.70, P=0.02) and HDL-C (r=0.55, P=0.03).Conclusion: The findings suggest that aerobic exercise-induced changes in omentin-1 in exercise trained smokers may be associated with the beneficial effects of exercise on reduced insulin resistance and lipid profile.

scholarly journals Aerobic Exercise Training Effects on Omentin-1, Insulin Resistance and Lipid Profile Among Male Smokers

2020 ◽  
Author(s):  
Seyed Maysam Mousavi ◽  
Ali Heidarianpour ◽  
Hassan Tavassoli
Keyword(s):  
Insulin Resistance ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Lipid Profile ◽  
Density Lipoprotein ◽  
Normal Weight ◽  
Aerobic Exercise Training ◽  
Lipoprotein Cholesterol ◽  
Control Group ◽  
Model Assessment

Abstract Background: Omentin-1 is a recently discovered circulating adipokine that plays a crucial role in modulating insulin resistance and diabetes. We investigated the effect of eight weeks of aerobic exercise training on serum omentin-1, insulin resistance and lipid profile in the smokers and non-smokers with normal weight. Methods: Nineteen male healthy and twenty male smokers were randomly assigned into healthy control group (C), healthy exercise group (E), control smoker group (CS) and exercise smoker group (ES). Exercise groups participated in an eight-week aerobic exercise training program (three times a week, 20-35 min per session at 55%-70% of maximum heart rate). Serum omentin-1 and insulin values were determined by ELISA and Homeostatic Model Assessment for Insulin Resistance (HOMA-IR), glucose and lipid profile was measured before and after the intervention. Paired samples t-test, one-way analysis of variance (One-way ANOVA) and post-hoc Tukey test were applied to analyze the data (p<0.05).Results: Aerobic exercise improved both serum omentin-1 and high lipoprotein cholesterol (HDL-C) in the exercise groups (p<0.05). Also, Exercise training reduced insulin, blood sugar, HOMA-IR, total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels (p<0.05). Omentin-1 was significantly correlated with insulin (r=-0.40, P=0.01), HOMA-IR (r=-0.38, P=0.04), TG (r=-0.40, P=0.01), TC (r=-0.49, P=0.02), LDL-C (r=-0.70, P=0.02) and HDL-C (r=0.55, P=0.03).Conclusion: The findings suggest that aerobic exercise-induced changes in omentin-1 in exercise trained smokers may be associated with the beneficial effects of exercise on reduced insulin resistance and lipid profile.

Adipocytes‐secreted hormone leptin, lipid profile and aerobic exercise program

2012 ◽  
Vol 1 (6) ◽  
pp. 292-297
Author(s):  
Eizadi Mojtaba ◽  
Kohandel Mahdi ◽  
Kasbparast JR Mehdi ◽  
Sarshin Amir
Keyword(s):  
Exercise Training ◽  
Aerobic Exercise ◽  
Lipid Profile ◽  
Exercise Program ◽  
Density Lipoprotein ◽  
Exercise Group ◽  
Lipoprotein Cholesterol ◽  
Control Group ◽  
Blood Samples ◽  
And Control

The adipocyte‐derived hormones leptin is known to increase in obesity and related disease. Thirty two non‐trained males (39±4.32 years, 176.5 – 6.5 ± 6.42 cm, and 31 ± 3.14 body fat %) were matched according to physical fitness enrolled in this study and divided to exercise and control group by accidentally. The participants of exercise group were completed an aerobic exercise program for 3 months (3 days/weekly) and control group were barred of exercise in this period. Anthropometrical measurements and fasting blood samples were obtained before and after interventions in two groups. Blood samples were collected in order to measuring serum leptin, triglyceride (TG), high density lipoprotein cholesterol (HDL), and Low density lipoprotein cholesterol (LDL). Pre‐ and post exercise independent variables were compared using a paired‐samples t‐test. Compared to pre‐training, the leptin levels decreased significantly (P<0.01) after aerobic exercise program in exercise group but not in the control subjects. Triglyceride concentration was decreased with exercise training whereas concentrations of LDL cholesterol did not change in exercise group (p≥0.05). Exercise training resulted in significant decrease in anthropometrical indexes (p Ë‚ 0.05) and a borderline significant increase in HDL (p=0.052). TG/HDL ratio were significantly decreased in exercise group by exercise training (p=0.028). All variable in control group remained no change in control group (p ≥ 0.05). These data suggest, despite lack significant changes in some lipid profile markers, aerobic exercise program can be improve systemic inflammation and TG/HDL ratio as a cardiovascular risk factor in obese subjects.

scholarly journals Effect of 8-week aerobic training on lipid profile, PYY3-36, and cortisol levels among obese women

2020 ◽  
Vol 42 (5) ◽  
pp. 511-519
Author(s):  
Vahid Aari Sarraf ◽  
Akram Ameghani ◽  
Alireza Ostadrahymy ◽  
Naser Aghamommadzadeh
Keyword(s):  
Exercise Training ◽  
Aerobic Exercise ◽  
Lipid Profile ◽  
Exercise Group ◽  
Aerobic Exercise Training ◽  
Control Group ◽  
Obese Women ◽  
Study Results ◽  
Significant Difference ◽  
Quasi Experimental

Background: Limited energy intake with physical activity is effective to reduce health problems associated with obesity. It has been shown that PYY3-36 level increased after intense exercise. This study investigated effect of exercise therapy on appetite suppression and weight loss among obese and/or overweight women. Methods: There was a quasi-experimental with a pretest-posttest design, two groups (control-exercise) study. Study population was overweight or obese women with 20-34 years old and body mass index 27-34 kg/m2. 13 women were randomly assigned in 2 groups (exercise group with 8 weeks of aerobic exercise training (n=7) and control group (n=6)). Weight, waist circumference, hip circumference, lipid profile, cortisol and PYY3-36 were measured at baseline and end of the study. Results: In baseline of study, there was no significant difference across the groups in factors mean (P>0.05).In control group, after 8 weeks, there was no significant difference in variables.(P>0.05) However, In exercise group significant decrease was observed in BMI, WHR, PYY3-36, TG, CHOLESTROL(TC) and LDL, compared to control group (P<0.05). Conclusion: Aerobic exercise within the 80% of heart rate reserve is beneficial in lipid profile, appetite management and modified anthropometric factors. These studies demonstrate that a cortisol change is not along with PYY3-36 changes. We suggest the longer exercise training for this purpose.

scholarly journals APOE genotype affects black-white responses of high-density lipoprotein cholesterol subspecies to aerobic exercise training

Metabolism ◽  
2008 ◽  
Vol 57 (12) ◽  
pp. 1669-1676 ◽  
Author(s):  
Thomas O. Obisesan ◽  
Robert E. Ferrell ◽  
Andrew P. Goldberg ◽  
Dana A. Phares ◽  
Tina J. Ellis ◽  
...  
Keyword(s):  
Exercise Training ◽  
High Density Lipoprotein ◽  
Aerobic Exercise ◽  
High Density Lipoprotein Cholesterol ◽  
Apoe Genotype ◽  
Density Lipoprotein ◽  
High Density ◽  
Aerobic Exercise Training ◽  
Lipoprotein Cholesterol

Effect of the Joint Administration of Selenium and Vitamin E in Combination with Regular Aerobic Exercise on Markers of Lipid Peroxidation and Glutathione Peroxidase in Diabetic Rats

2005 ◽  
Vol 15 (3) ◽  
pp. 266-278 ◽  
Author(s):  
Hyun-Tae Kim
Keyword(s):  
Vitamin E ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Acute Effect ◽  
Exercise Group ◽  
Diabetic Rats ◽  
Aerobic Exercise Training ◽  
Long Term Treatment

We investigated the effect of long-term treatment (6 wk) with selenium and vitamin E, in combination with aerobic exercise training, on malondialdehyde (MDA), oxidized low-density lipoprotein (ox-LDL), and glutathione peroxi-dase (GPx) in STZ-induced diabetic rats. The rats were assigned randomly to one of three treatment groups (n = 12 per group): 1) exercise group (EX), 2) selenium/vitamin E/exercise group (SVE), and 3) selenium/vitamin E group (SV). To estimate the acute effect of exercise, a 30-min endurance exercise was used. The MDA concentration was significantly lower in the SVE. The ox-LDL was significantly lower in the SVE and SV. The hepatic concentrations of selenium and vitamin E were significantly higher in the SVE. These results indicate that the increase in MDA is mildly attenuated in rats that were aerobically trained. Moreover, the joint administration of selenium and vitamin E with or without exercise training reduces the levels of ox-LDL.

Aerobic Exercise Training-Induced Decrease in Plasma Visfatin and Insulin Resistance in Obese Female Adolescents

2010 ◽  
Vol 20 (4) ◽  
pp. 275-281 ◽  
Author(s):  
Kyu-Jin Lee ◽  
Yun-A. Shin ◽  
Kyoung-Young Lee ◽  
Tae-Won Jun ◽  
Wook Song
Keyword(s):  
Insulin Resistance ◽  
Energy Expenditure ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Body Fat ◽  
Normal Weight ◽  
Female Students ◽  
Aerobic Exercise Training ◽  
Female Adolescents ◽  
Obese Female

The purpose of this study was to assess differences in the levels of plasma visfatin among female adolescents and changes in plasma visfatin and insulin resistance in obese female adolescents after 12 wk of aerobic exercise training. Twenty normal-weight female students (body-mass index [BMI] <22.9 kg/m2 and body fat ≤29.9) and 18 obese female students (BMI ≥25 kg/m2 and body fat ≥30%) participated in this study. Eleven obese students were assigned to an exercise group and completed a 12-wk aerobic exercise-training program that included four 40- to 50-min sessions per wk with an energy expenditure of 300–400 kcal/d. Seven obese students were assigned to a control group that received no exercise sessions or dietary restriction. The plasma visfatin levels of obese female adolescents were significantly higher (p < .05) than those of the normal-weight female adolescents. The plasma visfatin levels (294.00 ± 124.74 ng/ml to 185.55 ± 67.30 ng/ml, p < .01) and insulin resistance (p < .05) were significantly reduced after 12 wk of aerobic exercise. The results suggest that aerobic exercise resulting in an energy expenditure of 1,200–1,600 kcal/wk for 12 wk decreases plasma visfatin and insulin resistance in obese female adolescents.

scholarly journals Aerobic exercise training reduces blood pressure, angiotensin II and oxidative stress of patients with resistant hypertension: the EnRiCH trial

2021 ◽  
Vol 42 (Supplement_1) ◽  
Author(s):  
S Lopes ◽  
J Mesquita-Bastos ◽  
M Teixeira ◽  
D Figueiredo ◽  
J Oliveira ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Angiotensin Ii ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Resistant Hypertension ◽  
Exercise Group ◽  
Aerobic Exercise Training ◽  
Control Group ◽  
Exercise Training Program ◽  
And Oxidative Stress

Abstract Introduction Resistant hypertension is a major challenge of modern cardiovascular medicine, as it is a puzzling problem without a clear solution. Exercise training clearly reduces blood pressure (BP) and oxidative stress in patients with hypertension, however evidence is limited regarding resistant hypertension. Purpose To determine the effect of an aerobic exercise training program in BP, angiotensin II and oxidative stress in patients with resistant hypertension. Methods EnRicH is a prospective, two-center, single-blinded, randomized controlled trial with a parallel two-arm group. Sixty patients with resistant hypertension were randomly assigned in a 1:1 ratio to undergo a 12-week aerobic exercise training program (exercise) or usual care (control). The powered primary efficacy measure was 24-hour ambulatory systolic BP change from baseline. Secondary outcome measures included daytime and nighttime ambulatory BP, office BP, cardiorespiratory fitness, and oxidative stress and inflammatory biomarkers: Interferon-gamma (IFN-y), Angiotensin II, vascular endothelial growth factor (VEGF), and superoxide dismutase (SOD). Results Fifty-three patients (exercise n=26, control n=27) completed the study. Patients were mainly women (54.7%), with an office BP of 140.7±15.9/84.2±9.4 mm Hg and taking an average of 4.6 antihypertensive medications (median, 5; range, 3 to 7). At baseline, no differences were found between groups for the study outcomes and patient characteristics. Ambulatory systolic BP was reduced −7.1 mm Hg (95% CI, −12.8 to −1.4; P=0.015) in the exercise group (127.4±12.2 to 121.2±12.2, p=0.007) compared to control group (126.1±17.2 to 126.9±15.2, p=514) over 24-hour. In addition, 24-hour ambulatory diastolic BP (−5.1 mm Hg, −7.9 to −2.3, P=0.001), daytime ambulatory systolic (−8.4 mm Hg, −14.3 to −2.5, P=0.006), and diastolic BP (−5.7 mm Hg, −9.0 to −2.4, P=0.001) were also reduced in the exercise group compared to the control group. There were no differences in the change of nighttime ambulatory BP between groups. Cardiorespiratory fitness improved in the exercise group by 14% (4.7 ml.kg-1.min-1, P&lt;0.001), while it remained unchanged in the control group (−0.37 ml.kg-1.min-1, P=0.442). A significant between-group difference in favor of exercise group was found for IFN-y (−4.3 pg/mL, 95% CI: −7.1 to −1.5; P=0.003), Angiotensin II (−157.0 pg/mL, 95% CI: −288.1 to −25.9; P=0.020), VEGF (10.53 pg/mL, 95% CI: 0.60 to 22.54; P=0.035), and SOD (0.35 pg/mL, 95% CI: 0.10 to 0.58; P=0.009). Conclusions A 12-week moderate intensity aerobic exercise program reduced ambulatory BP, angiotensin II and oxidative stress in patients with resistant hypertension. The antihypertensive effects of exercise in patients with resistant hypertension may be mediated by positive changes in oxidative stress and inflammatory biomarkers. FUNDunding Acknowledgement Type of funding sources: Foundation. Main funding source(s): European Union through European Regional Development Fund – Operational Competitiveness Factors Program (COMPETE)Portuguese Government through FCT - Foundation for Science and Technology

Determining the effect size of aerobic exercise training on the standard lipid profile in sedentary adults with three or more metabolic syndrome factors: a systematic review and meta-analysis of randomised controlled trials

2021 ◽  
pp. bjsports-2021-103999
Author(s):  
Gina Wood ◽  
Emily Taylor ◽  
Vanessa Ng ◽  
Anna Murrell ◽  
Aditya Patil ◽  
...  
Keyword(s):  
Systematic Review ◽  
Metabolic Syndrome ◽  
Exercise Training ◽  
Aerobic Exercise ◽  
Lipid Profile ◽  
Meta Analysis ◽  
Density Lipoprotein ◽  
Aerobic Exercise Training ◽  
Meta Regression ◽  
Randomised Controlled

ObjectivesTo estimate the change in the standard lipid profile (SLP) of adults diagnosed with ≥3 metabolic syndrome (MetS) factors following aerobic exercise training (AET); and to investigate whether study/intervention covariates are associated with this change.DesignSystematic review with univariate meta-analysis and meta-regression.Data sourcesEnglish language searches of online databases from inception until July 2020.Eligibility criteria(1) Published randomised controlled human trials with study population ≥10 per group; (2) sedentary adults with ≥3 MetS factors but otherwise free of chronic disease, not pregnant/lactating; (3) AET-only intervention with duration ≥12 weeks; and (4) reporting pre–post intervention SLP outcomes.ResultsVarious univariate meta-analyses pooled 48 data sets of 2990 participants. Aerobic exercise training significantly (P<.001) improved all lipids (mmol/L mean difference ranges, 95% CIs): total cholesterol, –0.19 (–0.26 to –0.12) to –0.29 (−0.36 to –0.21); triglycerides, −0.17 (–0.19 to –0.14) to –0.18 (−0.24 to –0.13); high-density lipoprotein-cholesterol (HDL-C), 0.05 (0.03 to 0.07) to 0.10 (0.05 to 0.15); and low-density lipoprotein-cholesterol (LDL-C), –0.12 (–0.16 to –0.9) to –0.20 (−0.25 to –0.14). Meta-regression showed that intensity may explain change in triglycerides and volume may explain change in HDL-C and LDL-C.ConclusionAerobic exercise training positively changes the SLP of sedentary and otherwise healthy adults with ≥3 MetS factors. Adjusting AET intervention training variables may increase the effects of AET on triglycerides and HDL-C.PROSPERO registration numberCRD42020151925.

Sign in / Sign up

Export Citation Format

Share Document