scholarly journals Retrospective longitudinal analysis of the effects of postnatal weight gain on the timing and tempo of puberty and menarche in a cohort of Italian girls

Author(s):  
Stefano Stagi ◽  
Vittorio Ferrari ◽  
Simona Stefanucci ◽  
Marta Ferrari ◽  
Daniele Ciofi

Abstract Objectiveover the last few decades there has been a progressive decline in the average age of onset of pubertal development stages in both sexes. The increase in the prevalence of childhood obesity seems to play an important role in this phenomenon.Designwe undertook a retrospective, longitudinal evaluation of the average age of thelarche and menarche to evaluate the relationship between BMI and weight change during the first years of life and the timing and tempo of puberty.Methodswe evaluated data for 577 Italian girls born between 1995 and 2003. We collected the main auxological and clinical parameters, including age at B2 and at menarche, BMI SDS at B2 and menarche, gestational age and birth weight and Z-score change from birth weight (BW) to BMI at B2 and menarche.Resultsthe mean age of B2 was 10.06 ± 1.03 years and the mean age of menarche was 12.08 ± 1.02 years. Age at B2 and menarche were inversely correlated with BMI SDS (p < 0.0001). Both age at menarche and at thelarche have an inverse relationship with the Z-score change from birth weight and BMI at menarche and thelarche respectively (p < 0.0001).Conclusionsour data confirm a significant relationship between BMI and age of B2 and menarche. We observed a clear relationship among weight change during the first years of life, age at thelarche and menarche and the duration of puberty, demonstrating the importance of weight and weight gain in determining the timing and tempo of pubertal changes and growth.

2013 ◽  
Vol 4 (4) ◽  
pp. 280-284 ◽  
Author(s):  
K. M. Voegtline ◽  
K. A. Costigan ◽  
K. T. Kivlighan ◽  
J. L. Henderson ◽  
J. A. DiPietro

Associations between maternal salivary testosterone at 36 weeks’ gestation with birth weight and infant weight gain through 6 months of age were examined in a group of 49 healthy, pregnant women and their offspring. The diurnal decline of maternal testosterone was conserved in late pregnancy, and levels showed significant day-to-day stability. Elevated maternal morning testosterone level was associated with lower birth weight Z-scores adjusted for gestational age and sex, and greater infant weight gain between birth and 6 months. Although maternal testosterone levels did not differ by fetal sex, relations were sex-specific such that maternal testosterone had a significant impact on weight for male infants; among female infants associations were nonsignificant. Results highlight the opposing influence of maternal androgens during pregnancy on decreased growth in utero and accelerated postnatal weight gain.


Author(s):  
Amrita Behel ◽  
Leena Raje

Background: Menarche, one of the most reliable markers of pubertal maturity, is a result of a complex interplay between genetic and environmental factors. Since accelerated pubertal development is an important determinant of prognostic disease risk, especially in developing countries, attention must be focused on this important public health aspect.  Methods: Total 200 school-going girls aged between 10-15 years studying in municipal, public-funded and private schools in Mumbai were included in the study based on the inclusion criteria of having attained menarche only in the last three months. Sociodemographic and anthropometric details were collected using a structured schedule and physical activity data was collected using the physical activity questionnaire for older children and adolescents.Results: Socioeconomic status and family size were found to significantly influence the age of onset of menarche (p<0.001). Anthropometric indices of height, weight and BMI were found to have significant negative correlations indicating that taller, heavier girls reached menarche earlier than their shorter and lighter peers (p<0.000). Level of physical activity was also found to be an important contributing factor to age at menarche such that a higher level of physical activity was observed in girls with higher mean menarcheal age (p<0.000).  Conclusions: Age at menarche was found to be influenced by factors such as socioeconomic status, BMI and physical activity.   


2009 ◽  
Vol 94 (5) ◽  
pp. 1527-1532 ◽  
Author(s):  
Ken K. Ong ◽  
Pauline Emmett ◽  
Kate Northstone ◽  
Jean Golding ◽  
Imogen Rogers ◽  
...  

Abstract Context: Rapid postnatal weight gain has been associated with subsequent increased childhood adiposity. However, the contribution of rapid weight gain during specific infancy periods is not clear. Objective: We aimed to determine which periods of infancy weight gain are related to childhood adiposity and also to age at menarche in UK girls. Design, Setting, and Participants: A total of 2715 girls from a prospective UK birth cohort study participated in the study. Main Outcome Measures: Routinely measured weights and lengths at ages 2, 9, and 19 months were extracted from the local child health computer database. Body composition was assessed by dual-energy x-ray absorptiometry at age 10 yr, and age at menarche was assessed by questionnaire (categorized into three groups: &lt;12.0, 12.0–13.0, and &gt;13.0 yr). Results: Faster early infancy weight gain between 0 and 2 months and also 2 to 9 months were associated with increased body fat mass relative to lean mass at age 10 yr and also with earlier age at menarche. Each +1 unit gain in weight sd score between 0 and 9 months was associated with an odds ratio (95% confidence interval) = 1.48 (1.27–1.60) for overweight (body mass index &gt; 85th centile) at 10 yr, and 1.34 (1.21–1.49) for menarche at less than 12 yr. In contrast, subsequent weight gain between 9 and 19 months was not associated with later adiposity or age at menarche. Conclusions: In developed settings, rapid weight gain during the first 9 months of life is a risk factor for both increased childhood adiposity and early menarche in girls.


2018 ◽  
Vol 36 ◽  
pp. e300-e301
Author(s):  
Abubaker Swaib Lule ◽  
Benigna Namara ◽  
Helen Akurut ◽  
Lawrence Muhangi ◽  
Margaret Nampijja ◽  
...  

Author(s):  
Noor Dharmarha ◽  
Anuradha Konda

Background: Present study highlights that the worldwide trend of declining age at menarche is also seen in urban Indian girls. The aim of the study was to evaluate the age of menarche and to find out the factors associated with the timing of menarche.Methods: The study was an observational cross sectional study. 258 healthy, menstruating, adolescent girls aged 10-16 years, were selected by simple random sampling. Pre-designed structured questionnaires were distributed after taking informed consent. Anthropometric measurements were taken using standard techniques. The average age of menarche was calculated. The association of the age at menarche with the proposed factors was analyzed using chi square test and Pearson’s correlation coefficient. “P value” less than 0.05 was considered as significant.Results: The mean age at menarche was found to be 12.23±1.09 years. The study found a strong association between the respondent’s age at menarche and her sister’s age at menarche (p=0.002). The study also found a strong association between age at menarche and the socioeconomic status (p=0.021). This study however found no association of menarcheal age with factors like birth weight, type of diet, frequency of milk intake, body mass index, waist hip ratio, amount of exercise, unstable environment at home and psychosocial stress.Conclusions: The worldwide trend of declining age at menarche is also seen in urban Indian girls. This trend underlines the importance of investigating the factors associated with it and studying the future implications of a lower age at menarche.


Author(s):  
Andraea Van Hulst ◽  
Tracie A. Barnett ◽  
Gilles Paradis ◽  
Marie‐Hélène Roy‐Gagnon ◽  
Lilianne Gomez‐Lopez ◽  
...  

2007 ◽  
Vol 22 (11) ◽  
pp. 1881-1889 ◽  
Author(s):  
Christian Plank ◽  
Iris Östreicher ◽  
Katalin Dittrich ◽  
Rüdiger Waldherr ◽  
Manfred Voigt ◽  
...  

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