scholarly journals Relationship between the Height of Fibular Head and the Incidence and Severity of Knee Osteoarthritis

Author(s):  
Xinghui Xu ◽  
Jun Li ◽  
Deping Yao ◽  
Pan Deng ◽  
Boliang Chen ◽  
...  

Abstract Objective: To investigate the correlation between fibular head height and the incidence and severity of varus knee osteoarthritis based on three-dimensional reconstruction of the knee joint.Methods: The data of knee joint imaging in our hospital from June 2018 to June 2020 were collected. The degree of varus deformity of the knee was assessed at the superior hip-knee-ankle angle of the X-rays. Three-dimensional reconstruction of patient computed tomography(CT)data was performed by mimics software. The fibular head height, joint line convergence angle (JLCA) and medial proximal tibial angle (MPTA) were measured in a three-dimensional model. The patients were divided according to the Kellgren-Lawrence grade: group A: grade 0, group B: grade I, group C: grade II, group D: grade III, and group E: grade IV. The differences in age, gender, height, weight, body mass index(BMI), fibular head height, and degree of varus deformity (JLCA, MPTA, and coxa-knee-ankle angle) were compared. Ordinal multivariate logistic regression was used to analyze the correlation between fibular head height and Kellgren-Lawrence grade.Pearson correlation was used to analyze the correlation between fibular head height and Kellgren-Lawrence grade.Results: 232 patients (232 knees) were finally included in the study, with Kellgren-Lawrence grades of 28 in group A, 31 in group B, 49 in group C, 53 in group D, and 71 in group E. The differences in age, gender, height, body mass index, fibular head height, JLCA, MPTA, and hip-knee-ankle angle among the five groups were statistically significant (P < 0.05), and the differences in body weight were not statistically significant (P > 0.05). There were significant differences in fibular head height, JLCA, JLCA and hip-knee-ankle angle between different groups (P < 0.05). Furthermore, there were significant differences in JLCA and hip-knee-ankle angle (P < 0.05), and both JLCA and hip-knee-ankle angle increased with severe aggravation of Kellgren-Lawrence grade. Furthermore, both fibular head height and MPTA decreased as the Kellgren-Lawrence grade was severely aggravated. There was a significant negative correlation between Kellgren-Lawrence grade and fibular head height (r = -0.812, P < 0.001). Furthermore, there was a significant negative correlation between fibular head height and hip-knee-ankle angle (r = -0.7905, P < 0.001). When Kellgren-Lawrence grade III and IV knees were considered as disease, ROC curve analysis showed a cut-off value of 10.63 for fibular head height and an AUC of 0.872.Conclusion: The height of fibular head in patients with varus knee osteoarthritis is smaller than that in non-osteoarthritis patients. In addition to body mass index, fibular head height is a risk factor for the pathogenesis of varus knee osteoarthritis,the smaller the fibular head height, the more severe the severity of osteoarthritis and the more severe the degree of varus deformity.

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Li Zhang ◽  
Geng Liu ◽  
Bing Han ◽  
Yuzhou Yan ◽  
Junhua Fei ◽  
...  

Malalignment of the lower limbs is the main biomechanical factor for knee osteoarthritis (KOA). The static hip-knee-ankle angle (S-HKAA) measured from radiograph is regarded as the “gold standard” of the malalignment. However, many evidences showed that the S-HKAA has no significant correlation with the knee dynamic-load distribution, unlike the dynamic HKAA (D-HKAA). The purpose of this study was to quantitatively analyze the D-HKAA and investigate the relationship between D-HKAA and S-HKAA for both KOA and healthy participants. In this paper, twenty-five healthy subjects and twenty-five medial compartment KOA (M-KOA) patients were recruited. Three-dimensional motion analysis and standing lower-limbs-full-length radiograph were utilized to obtain the D-HKAA and S-HKAA, respectively. The results showed that the mean D-HKAA was more varus than the S-HKAA ( p < 0.05 ). For the mean D-HKAA, larger varus angle was observed in swing phase than stance phase ( p < 0.05 ). Compared with healthy subjects, the M-KOA patients had remarkably smaller S-HKAA and D-HKAA during gait cycle ( p < 0.01 ). For the relationship between the S-HKAA and mean D-HKAA, no significant correlation was found for both healthy subjects and M-KOA patients ( r < 0.357 , n = 25 , p > 0.05 , Spearman correlation analysis). In conclusion, the S-HKAA was limited to predict the D-HKAA for both M-KOA patients and healthy subjects. The D-HKAA should be given more attention to the orthopedist and the designer of knee brace and orthotics.


2011 ◽  
Vol 71 (5) ◽  
pp. 655-660 ◽  
Author(s):  
Andrew K Wills ◽  
Stephanie Black ◽  
Rachel Cooper ◽  
Russell J Coppack ◽  
Rebecca Hardy ◽  
...  

IntroductionThe authors examined how body mass index (BMI) across life is linked to the risk of midlife knee osteoarthritis (OA), testing whether prolonged exposure to high BMI or high BMI at a particular period has the greatest influence on the risk of knee OA.MethodsA population-based British birth cohort of 3035 men and women underwent clinical examination for knee OA at age 53 years.Heights and weights were measured 10 times from 2 to 53 years. Analyses were stratified by gender and adjusted for occupation and activity levels.ResultsThe prevalence of knee OA was higher in women than in men (12.9% (n=194) vs 7.4% (n=108)). In men, the association between BMI and later knee OA was evident at 20 years (p=0.038) and remained until 53 years (OR per z-score 1.38 (95% CI 1.11 to 1.71)). In women, there was evidence for an association at 15 years (p=0.003); at 53 years, the OR was 1.89 (95% CI 1.59 to 2.24) per z-score increase in BMI. Changes in BMI from childhood in women and from adolescence in men were also positively associated with knee OA. A structured modelling approach to disentange the way in which BMI is linked to knee OA suggested that prolonged exposure to high BMI throughout adulthood carried the highest risk and that there was no additional risk conferred from adolescence once adult BMI had been accounted for.ConclusionThis study suggests that the risk of knee OA accumulates from exposure to a high BMI through adulthood.


2017 ◽  
Vol 69 (8) ◽  
pp. 1266-1270 ◽  
Author(s):  
Adam G. Culvenor ◽  
David T. Felson ◽  
Jingbo Niu ◽  
Wolfgang Wirth ◽  
Martina Sattler ◽  
...  

2019 ◽  
Vol 27 ◽  
pp. S368 ◽  
Author(s):  
I.P. Munugoda ◽  
D.A. Aitken ◽  
W. Wirth ◽  
F. Eckstein

2009 ◽  
Vol 36 (3) ◽  
pp. 592-597 ◽  
Author(s):  
YASUSHI AKAMATSU ◽  
NAOTO MITSUGI ◽  
NAOYA TAKI ◽  
RYOHEI TAKEUCHI ◽  
TOMOYUKI SAITO

Objective.To assess the relationship between bone mineral density (BMD) and varus deformity arising from bone structural changes caused by knee osteoarthritis (OA) in postmenopausal women.Methods.This cross-sectional study involved 135 consecutive postmenopausal female patients who had varus knee OA and a Kellgren-Lawrence grade ≥ 2. Knee radiographs were obtained with the patient standing on one leg, and subjects were classified into 3 tertile groups according to femorotibial angle, which was taken as a measure of varus knee OA severity. We also measured the 3 subangles that make up the femorotibial angle, and focused on the varus inclination of the tibial plateau. BMD was measured in the lumbar spine, femoral neck, and medial and lateral tibial condyles using dual-energy X-ray absorptiometry. Differences between femorotibial angle tertile groups were assessed, and associations between femorotibial sub-angles and BMD values at various points were evaluated.Results.After adjustment for age and body mass index, there was no significant association between the varus inclination of the tibial plateau and lumbar spine BMD. A weak but statistically significant negative correlation existed between varus inclination of the tibial plateau and BMD at the ipsilateral proximal femur and lateral tibial condyle.Conclusion.Varus inclination of the tibial plateau was significantly more severe in the femorotibial angle tertile 3 group, and in patients with lower BMD in the ipsilateral lower limb. Varus knee OA may result not only from cartilage loss but also from structural changes of the bone.


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