scholarly journals Histological and Ultrastructural Study on the Effect of Celery Juice on Ethylene Glycol Induced Urolithiasis in Male Albino Rats

2017 ◽  
Vol 29 (s4) ◽  
Keyword(s):  
Ethylene Glycol ◽  
Ultrastructural Study ◽  
Albino Rats

scholarly journals Ameliorative effect of Aerva lanata against nephrolithiasis following chronic administration of Ethylene glycol in male wistar Albino rats

2021 ◽  
Author(s):  
Ankul Singh S ◽  
Gowri K ◽  
Chitra V
Keyword(s):  
Ethylene Glycol ◽  
Urine Volume ◽  
Chronic Administration ◽  
Negative Control ◽  
Albino Rats ◽  
Standard Group ◽  
Alcoholic Extract ◽  
Health Crisis ◽  
Group I ◽  
Wistar Albino Rats

Abstract Nephrolithiasis appear to be a major health crisis among the population with serious medical related consequences throughout the lifetime of patient. The aim of the study was to evaluate the preventive effect of the hydro-alcoholic extract of A. lanata roots on Urolithiasis rats. Thirty adults male wistar Albino rats weighing 200 – 250 g were divided into five groups comprising 6 rats in each. Group I Served as positive control with water ad libitum. Group II as negative control which is disease treated group receiving 0.75% ethylene glycol mixed with drinking water for 28 days. Group III chosen as standard group receiving ethylene glycol for first 14 days and Cystone 750 mg/Kg from day 15 till day 28. Group IV and V received ethylene glycol for first 14 days and treatment regimen of LD (400 mg/Kg) and HD 800 mg/Kg orally from day 15 till day 28. Invitro studies like Nucleation, Aggregation and Growth assays were performed. Urine volume and pH was collected and observed for change in appearance, pH, odour and turbidity. Extract was given by preparing suspension and stability was observed by measuring its parameters. On Day 29, the kidneys were dissected and histopathology was done to check tubular injury. There was Increase in urine volume, enhanced excretion of urinary constituents like citrate, oxalate etc. and improving clearance rate. Improvement in pH and antioxidant activity was observed in treated groups. The extract showed that it has prominent effect on nephrolithiasis and has better safety profile in the dose given.

Mineralization during matrix-vesicle-mediated mantle dentine formation in molars of albino rats: a microanalytical and ultrastructural study

1996 ◽  
Vol 284 (2) ◽  
pp. 223-230 ◽  
Author(s):  
U. Stratmann ◽  
K. Schaarschmidt ◽  
H. P. Wiesmann ◽  
U. Plate ◽  
H. J. Höhling
Keyword(s):  
Ultrastructural Study ◽  
Matrix Vesicle ◽  
Albino Rats

scholarly journals THE PROTECTIVE AND THERAPEUTIC EFFECT OF CORN SILK EXTRACT ON UROLITHIATIC AND HYPERTENSIVE RATS INDUCED BY ETHYLENE GLYCOL

2021 ◽  
Vol 2 (4) ◽  
pp. 151-160
Author(s):  
Abdulrhman A. Almadiy ◽  
Afrah Ali Alasbahy ◽  
Hussein S. Gumaih ◽  
E. S. Nasr ◽  
Maher A. Al-Maktari
Keyword(s):  
Ethylene Glycol ◽  
Renal Stone ◽  
Stone Formation ◽  
Radical Scavenging ◽  
Positive Control ◽  
Normal Diet ◽  
Herbal Remedies ◽  
Albino Rats ◽  
Corn Silk ◽  
The Impact

Renal stone is one of the most problems worldwide. They are affected by different factors such as environmental effectors such as nutrient as well as family history. Corn silk (CS) used as antiurolythiasis. This study investigated the impact of corn silk extract as the management of renal stone formation, hypertension, and hepatoprotective. This work has been carried out on rats at Faculty of science Sana’a University, University of Science, and Technology Laboratories. Twenty-four male albino rats with weighing range between (200 g to 250g) were taken. They were divided in four groups (each group consists of 6animals). The first group of rats took normal diet and named as negative control (Co) whereas, the second group took normal diet with ethylene glycol (EG) (0.75%) and 1% ammonium chloride (AC) for 28 days and serve as positive control (Po). The third and fourth groups took the same substances as inPo group with 200 mg/kg and 400 mg/kg of corn silk (CS) for 28 days respectively.Blood samples were collected from rats on last day of the experiment. All the tested samples showed a significant antioxidant DPPH radical scavenging activity and a notifiable decrease in serum aldosterone hormone, angiotensin comforting enzyme urea and creatinine levels comparedto positive control. Shown to significantly increased AST, ALT, and LDH in comparison to the urolithiatic group and near of normal group.In conclusion, the present study emphasizes the safe herbal remedies of CS as anti-hypertensive and antioxidants, as well as antiurolithiatic and hepatoprotective.

scholarly journals Curative Effects of Ethanol Extract of Prosopis Farcta (Syrian Mesquite) Against Ethylene Glycol Induced Urolithiasis in Male Albino Rats

2021 ◽  
Vol 9 (2) ◽  
pp. 89-96
Author(s):  
Kowan M. Ahmed ◽  
Sarbast A. Mahmud
Keyword(s):  
Ethylene Glycol ◽  
Tap Water ◽  
Control Group ◽  
Albino Rats ◽  
Therapeutic Effects ◽  
Fruit Extract ◽  
Kidney Weight ◽  
Prosopis Farcta ◽  
Group A ◽  
Group B

The present study was designed to evaluate the antiurolithiatic activity of Prosopis farcta (P. farcta) ethanol fruit extract in ethylene glycol (EG) induced urolithiasis in male albino rats. Lithiasis was induced by oral administration of EG 1% in male albino rats for 28 days. Seventy eight male albino rats weighing 250-300g were used and divided into six experimental groups. Group A is a control group received standard rat chow and tap water ad libitum, while, rest of groups namely group B, C, D, E, F animals received 1% EG in water for 28 days, then from day 15 to day 28 in addition to EG administration, group C received cystone, group D, E and F received 100, 200 and 300 mg/kg body weight (B.W.) of ethanol fruit extract of P. farcta respectively. On day 28, blood was collected for serum biochemical (serum uric acid, creatinine, urea, electrolytes measurements, malondialdehyde (MDA) and superoxide dismutase (SOD)) determinations. While urine was collected to microscopic analysis of formed crystals besides the kidney weight/ B.W. ratio and B.W. gain/ loss values were determined. Intermediate dose (200mg/kg B.W.) of P. farcta extract significantly decreased serum creatinine, urea, MDA and non-significantly recovered SOD toward control value in group E as compared to group B, also significant elevation in kidney weight/ B.W. ratio and reduction in B.W. gains in group B occurred as compared with group A. In conclusion: P. farcta fruit extract has potentially therapeutic effects on EG induced kidney stone which can be used as effective antiurolithiatic agent rather than cystone.

Effects of Extract of Spilanthes uliginosa (SW) on Total Protein, Albumin, Total and Conjugated Bilirubin in Ethylene Glycol Exposed Albino Rats

2015 ◽  
Vol 11 (1) ◽  
pp. 53-58
Author(s):  
A.J. Uraku ◽  
N. Ezeani ◽  
C. Ezeali ◽  
F.U. Ali ◽  
C.A. Afiukwa ◽  
...  
Keyword(s):  
Ethylene Glycol ◽  
Total Protein ◽  
Albino Rats ◽  
Conjugated Bilirubin

The Inhibitory Ability of Orobanche Extract on Calcium Oxalate Lithiasis in Male Albino Rats

2020 ◽  
Author(s):  
A. M. Kamal ◽  
M. S. Taha
Keyword(s):  
Treatment Group ◽  
Ethylene Glycol ◽  
Kidney Tissue ◽  
Inhibitory Effect ◽  
Control Group ◽  
Albino Rats ◽  
Potential Candidate ◽  
Group 4 ◽  
Group 5 ◽  
Group 2

The present study aimed to evaluate the inhibitory effect of Orobanche extract in ethylene glycol induced nephrolithiasis. Thirty male albino rats were divided into five groups each group contains 6 animals, group (1) control group, group (2) animals were supplied with 0.75% ethylene glycol in drinking water, group (3) animals were administrated Orobanche extract 3g/kg orally, group (4) animals were administrated Cystone 500 mg/kg in addition to 0.75% ethylene glycol, group (5) animals were administrated Orobanche extract 3g/kg orally in addition to 0.75% ethylene glycol the experiment continued for 28 days. Serum and the kidney homogenates were analyzed for various biochemical parameters and urine was examined microscopically for crystals. Orobanche treatment group and Cystone treatment group significantly decreased phosphorus, Calcium and Oxalate in kidney tissue of nephrolithiasis rats and significantly decreased kidney and liver marker in serum of nephrolithiasis rats. Conclusion this result revealed that Orobanche extract could be a potential candidate for phytotherapy against nephrolithiasis.

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