scholarly journals The Hand Mirror Image: Which is the Lineage in the End?

2021 ◽  
Vol 8 (1) ◽  
pp. C10-12
Author(s):  
Kalyani N Bapat ◽  
Rajesh B Patil

According to the World Health Organization (WHO) 2016 classification, acute promyelocytic leukemia (APL) is placed in the category of AML with recurrent cytogenetic abnormalities. Cytogenetic confirmation of reciprocal translocation t(15:17) is essential criteria for diagnosis of this entity. However, these tests may have a significant time delay and it is usually the characteristic morphology of the abnormal promyelocytes which helps to pick up the diagnosis early and alert the clinician to initiate treatment promptly. The two variants commonly described are the hypergranular and the variant (M3v) forms, but knowledge of other rarer morphological variants of APL becomes crucial in certain situations for the hematopathologist. To highlight this phenomenon, we describe a case report of a 9-year-old female who presented with a hand mirror morphology of the abnormal promyelocytes.

1970 ◽  
Vol 1 (1) ◽  
pp. 56-58
Author(s):  
SC Kohli ◽  
UK Shrestha ◽  
VM Alurkar ◽  
A Maskey ◽  
M Parajuli ◽  
...  

The global program to eliminate Lymphatic Filariasis created by The World Health organization in 1997 is based on mass administration of single annual doses of diethylcarbamazine ( DEC) plus albendazole in non African regions and of albendazole plus ivermectin in Africa. The usual side effects of DEC treatment include fever, chills, arthralgia, headaches, nausea, and vomiting. Albendazole is associated with relatively few side effects consisting of occasional nausea, vomiting, abdominal pain, headache, reversible alopecia, elevated aminotransferases and rarely leucopenia and rash. We report a case of polyneuropathy in a young individual following DEC and albendazole during mass drug administration. Keywords: Albendazole; DEC; Polyneuropathy. DOI: http://dx.doi.org/10.3126/njms.v1i1.5800   Nepal Journal of Medical Sciences. 2012; 1(1): 56-58


2021 ◽  
Vol 6 (12) ◽  
pp. 46-55
Author(s):  
Derya GERESİNLİ ◽  
Asiye AKYOL

The COVID-19 epidemic, which the World Health Organization regards as a "pandemic", continues to be perceived as a threat to survive for many people living in different parts of the world. The virus is a global epidemic; It affects everyone's lives negatively regardless of religion, language, race, gender, socioeconomic and sociocultural differences. Facing with a threat that develops suddenly, changes daily habits and can result in death is not a common situation for people, and the perception of threat and uncertainty it creates makes it difficult to cope with the situation. Uncertainty is an important part of the illness experience, and our response to uncertainty can significantly affect our illness outcomes. Mishel's Uncertainty Theory in Illness helps to find meaning in uncertainty again and to develop healthy coping mechanisms. The role of nurses in the management of uncertainty regarding illness; to facilitate the process and to adapt the patient to healthy reactions. In this case report; Within the scope of the Uncertainty in Illness Theory of Mishel, a 39-year-old nurse who was diagnosed with Covid 19 was planned to find a meaning in the disease again by planning the care process. It was stated that the theory can be applied in the acute illness as well as in the chronic illness.


2019 ◽  
Vol 7 ◽  
pp. 2050313X1982891
Author(s):  
Miguel Angel Moyón Constante ◽  
Fernando Xavier Moyón Constante ◽  
Jorge Fernando Tufiño ◽  
Andres Cárdenas Patiño ◽  
Gabriel Alejandro Molina ◽  
...  

Mixed adenoneuroendocrine carcinomas are rare tumors that contain both an exocrine and an endocrine component. Since the latest classification by the World Health Organization and with the aid of immunostaining, more mixed adenoneuroendocrine carcinomas are now identified and diagnosed. Nonetheless, our knowledge of these tumors is still limited, notably concerning gastric variants, as the cases reported in the literature are very limited. The clinical and surgical treatment, including the chemotherapy schemes, the prognosis, and recurrence still represent challenges for the medical teams. We present the case of a 62-year-old woman. After an upper endoscopy revealed multiple polyps and a low-grade neuroendocrine tumor, a D2 radical gastrectomy was performed. A low output esophageal anastomotic leak was discovered in the postoperative period and successfully managed. Pathology revealed a gastric mixed adenoneuroendocrine carcinoma, the first case of this kind reported in Ecuador. Patient is doing well and under constant surveillance up until her 13th postoperative month.


2020 ◽  
Author(s):  
Serge ZIGABE ◽  
Etienne Kajibwami ◽  
Guy-Quesney Mateso ◽  
Benjamin Ntaligeza

Abstract COVID-19 started as a cluster of pneumonia cases in Wuhan City, the Province of Hubei, China, in December 2019. It spread to many regions of China, outside of China and was declared a pandemic by the World Health Organization (WHO) on March 11th, 2020. Initially Africa had no case and now the continent is reporting an increasing number of confirmed cases in an exponential manner (1,2).


2021 ◽  
Vol 11 (2-S) ◽  
pp. 1-3
Author(s):  
A Otljanski ◽  
K Kipevska

In 2019 year the world was attacked with corona virus (SARS-CoV-2) and in march 2020, the World Health Organization (WHO) declared the COVID-19 outbreak a pandemic.The symptoms and clinical state in this COVID-19 infection was different, from asymptomatic to mild and severe symptoms, which presented different form of disease: mild, moderate or severe, with or without complications. We presented case with COVID 19 pneumonia as one of the form of COVID infection, with diagnosis, treatment and all investigations we done in our hospital. With complex treatment of this virus infection we successful improved the clinical state of patients with COVID 19 pneumonia. Keywords: coronavirus, SARS-CoV-2, COVID-19, COVID 19 pneumonia


Author(s):  
Valeria Saladino ◽  
Stefano Eleuteri ◽  
Elisa Zamparelli ◽  
Monica Petrilli ◽  
Valeria Verrastro

Children and adolescents are too often victims of sexual abuse and harassment. According to the World Health Organization (WHO), approximately 150 million girls and 73 million children <18 have been victims of violence and sexual exploitation during their childhood. Data show that females are more likely to be a victim of abuse and violence than males (20% vs. 5–10%). Such abuses lead to long-term psychophysical and relational consequences and victims are often afraid of asking for support from both parents and professionals. This case report shows the story of a 17-year-old adolescent, Sara, involved by her mother in a strategic counseling process, to solve BDSM-type sexual addiction (slavery and discipline, domination and submission, sadism and masochism), self-aggressive behavior, and alcohol abuse issues. The strategic counseling process is structured in 15 sessions and was based on problem-solving techniques and corrective behavioral strategies. During the sessions, it emerged that Sara had been a victim of sexual violence at the age of 6 and that she had never talked about the rape with anyone. At the age of 12, she began to experience social anxiety and shame, feelings that led her to use alcohol and seek violent sexual partners and bondage relationships. During the counseling sessions, Sara elaborated on her trauma, becoming more aware of her resources and her desires, and she learned to manage the sense of guilt and shame associated with the violence suffered, through alternative strategies. At the end of the process, Sara normalized her relationship with sex and alcohol, regaining her identity.


2021 ◽  
Vol 9 (03) ◽  
pp. 607-611
Author(s):  
Khalloufi C. ◽  
◽  
Ibnoulkhatib S. ◽  
El Kebir A. ◽  
Karkouri M. ◽  
...  

The debate persists about the inflammatory or tumoral, benign or malignant nature of the Inflammatory myofibroblastic tumors (TMI). Radioclinically, they can mimic a malignant neoplasm, although they are classified as intermediate by the World Health Organization (WHO). The diagnosis is almost always made by pathological examination. The treatment is poorly codified but the management is usually surgical. The removal of these tumors is a challenge when the mass is developed at the expense of or in the vicinity of noble organs. Several therapies have been tested to overcome the limitations of surgery, the results are variable. These tumors rarely affect the digestive tract. We propose the study of a case of myofibroblastic tumor developed at the expense of the omentum, five months after a cesarean section, in order to try to determine if it is a rare complication of the postpartum or a fortuitous combination.


2018 ◽  
Vol 2 (1) ◽  
pp. 10-11
Author(s):  
Bharat Sharma

The drug Dapsone is a component of the World Health Organization multidrug therapy being used against leprosy. Although it has shown a good efficacy during the years, a few subjects develop adverse drug reactions associated with dapsone .We report a case of a patient who was prescribed dapsone as part of multiple drug therapy for leprosy following which he developed Dapsone induced Hypersensitivity Syndrome (DHS). He was prescribed steroids with a tapering dose. His condition worsened after weaning of the oral steroids. He also developed steroid-induced diabetes which was stabilized using anti-diabetic drugs.


2020 ◽  
pp. 112067212097039
Author(s):  
Lijuan Tang ◽  
Hua Xu ◽  
Huanhuan Gao ◽  
Huasheng Yang ◽  
Shuxia Chen ◽  
...  

Low-grade myofibroblastic sarcoma (LGMS) is an exceedingly rare, malignant tumor with myofibroblastic differentiation. It frequently occurs in the oral cavity and extremities, despite being classified as a distinct entity by the World Health Organization (WHO). Here, we report a rare case of orbital LGMS occurring in an 11-month-old baby with a 3.2 × 2.4 × 2.1 cm mass. LGMS was diagnosed based on the histological and immunohistochemical findings. Previous literature suggests that surgical resection with clear margins is an appropriate method for the treatment of LGMS, and combined adjuvant therapy (local radiotherapy with or without chemotherapy) can improve the prognosis, but further studies are needed.


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