Risk Factors for Hospitalization and Death From COVID-19 in South Sudan and Eastern Democratic Republic of the Congo

2021 ◽  
Author(s):  
Eva Leidman ◽  
Shannon Doocy ◽  
Grace Heymsfield ◽  
Abdou Sebushishe ◽  
Mbong Eta Ngole ◽  
...  
2021 ◽  
Vol 70 ◽  
pp. 102581
Author(s):  
Margaret Carrel ◽  
Seungwon Kim ◽  
Melchior Kashamuka Mwandagalirwa ◽  
Nono Mvuama ◽  
Joseph A. Bala ◽  
...  

Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2628
Author(s):  
Marius Baguma ◽  
Espoir Bwenge Malembaka ◽  
Esto Bahizire ◽  
Germain Zabaday Mudumbi ◽  
Dieudonné Bahati Shamamba ◽  
...  

This comparative cross-sectional study aimed to better understand the respective contributions of protein malnutrition and cassava-derived cyanide poisoning in the development of konzo. We compared data on nutritional status and cyanide exposure of school-age adolescent konzo-diseased patients to those of non-konzo subjects of similar age from three areas in the Eastern Democratic Republic of the Congo. Our results show that konzo patients had a high prevalence of both wasting (54.5%) and stunting (72.7%), as well as of cyanide poisoning (81.8%). Controls from Burhinyi and those from Idjwi showed a similar profile with a low prevalence of wasting (3.3% and 6.5%, respectively) and intermediate prevalence of stunting (26.7% and 23.9%, respectively). They both had a high prevalence of cyanide poisoning (50.0% and 63.0%, respectively), similar to konzo-patients. On the other hand, controls from Bukavu showed the lowest prevalence of both risk factors, namely chronic malnutrition (12.1%) and cyanide poisoning (27.6%). In conclusion, cassava-derived cyanide poisoning does not necessarily coexist with konzo outbreaks. The only factor differentiating konzo patients from healthy individuals exposed to cyanide poisoning appeared to be their worse nutritional status. This further suggests that, besides the known role of cyanide poisoning in the pathogenesis of konzo, malnutrition may be a key factor for the disease occurrence.


2018 ◽  
Vol 43 (4) ◽  
pp. 761-767
Author(s):  
Fiston Ikwa Ndol Mbutiwi ◽  
François Bompeka Lepira ◽  
Taty Latelabwe Mbutiwi ◽  
Donat Kenge Kumakuma ◽  
Gloria Kikumbi Kumbukama ◽  
...  

2016 ◽  
Vol 26 (4) ◽  
pp. 386-390 ◽  
Author(s):  
P.M. Ilunga ◽  
O. Mukuku ◽  
P.M. Mawaw ◽  
A.M. Mutombo ◽  
T.K. Lubala ◽  
...  

Subject African politics and security to end-2017. Significance Key regional leaders are set to step down from national and party presidencies in Angola and South Africa, presidents in Nigeria and Zimbabwe are in ill health, while growing displacement crises in the Central African Republic (CAR) and the Democratic Republic of the Congo (DRC) could worsen without increased international funding and support. Although famine risks have lessened in South Sudan, conflict and instability will persist in Nigeria and Somalia as renewed insurgency threats grow.


Subject Prospects for East Africa and the Great Lakes in 2018. Significance Questions of democratic legitimacy and transition will dominate the outlook for East Africa and the Great Lakes over the coming year, in the context of election controversies (Democratic Republic of the Congo (DRC), Kenya), constitutional term-limit issues (Burundi, DRC, Rwanda, Uganda) and deepening political conflicts (Ethiopia, Somalia, South Sudan). Receding economic headwinds will support a moderate growth recovery for several states (Ethiopia, Rwanda, Uganda), but political risk will weigh on the outlook for others (Burundi, DRC, Kenya, South Sudan).


Author(s):  
Hannah Elena Dönges ◽  
Janosch Kullenberg

Over the last fifteen years, the Protection of Civilians (POC) has become a central task of peacekeeping operations. Despite this prominent role and the mediatized criticism on protection failures, knowledge about how protection functions in practice is actually quite limited. This chapter, therefore, examines protection practices on the ground in the Democratic Republic of the Congo (MONUSCO) and South Sudan (UNMISS) and connects the findings to the existing literature. In this way, the chapter identifies a number of operational issues in the administration, planning, and coordination of protection, and describes how these issues have contributed to the success and/or failure of specific protection efforts across missions. This chapter argues that despite the practical overlap and implications for the physical security of populations in armed conflict, the POC, and Women, Peace, and Security agendas have evolved in rather disconnected ways. At the same time, we observe that the emergence of the WPS agenda has facilitated increased recognition of gendered vulnerabilities in protection.


2020 ◽  
Author(s):  
Nicholas F. Brazeau ◽  
Cedar L. Mitchell ◽  
Andrew P. Morgan ◽  
Molly Deutsch-Feldman ◽  
Oliver John Watson ◽  
...  

ABSTRACTBackgroundReports of P. vivax infections among Duffy-negative hosts have begun to accumulate throughout sub-Saharan Africa. Despite this growing body of evidence, no nationally representative epidemiological surveys of P. vivax in sub-Saharan Africa nor population genetic analyses to determine the source of these infections have been performed.MethodsTo overcome this critical gap in knowledge, we screened nearly 18,000 adults in the Democratic Republic of the Congo (DRC) for P. vivax using samples from the 2013-2014 Demographic Health Survey. Infections were identified by quantitative PCR and confirmed with nested-PCR. P. vivax mitochondrial genomes were constructed after short-read sequencing. Risk factors, spatial distributions and population genetic analyses were explored.FindingsOverall, we found a 2.96% (95% CI: 2.28%, 3.65%) prevalence of P. vivax infections across the DRC. Nearly all infections were among Duffy-negative adults (486/489). Infections were not associated with typical malaria risk-factors and demonstrated small-scale heterogeneity in prevalence across space. Mitochondrial genomes suggested that DRC P. vivax is an older clade that shares its most recent common ancestor with South American isolates.InterpretationP. vivax is more prevalent across the DRC than previously believed despite widespread Duffy-negativity. Comparison to global and historical P. vivax sequences suggests that historic DRC P. vivax may have been transported to the New World on the wave of European expansion. Our findings suggest congolese P. vivax is an innocuous threat given its relatively flat distribution across space, lack of malaria risk factors, and potentially ancestral lineage.FundingNational Institutes of Health and the Wellcome Trust.


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