scholarly journals ELIZABETHKINGIA MENINGOSEPTICA BACTEREMIA IN A NEONATE: A RARE CASE REPORT FROM A TERTIARY CARE CENTRE OF TRIPURA

2020 ◽  
Vol 8 (10) ◽  
pp. 63-66
Author(s):  
Sibabrata Bhattacharya ◽  
◽  
Rima Das ◽  
Ankan Chakrabarti ◽  
Tapan Majumdar ◽  
...  
Keyword(s):  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Antimicrobial Susceptibility Pattern ◽  
Male Baby ◽  
Elizabethkingia Meningoseptica ◽  
Rare Case Report ◽  
History Of ◽  
Vitek 2 ◽  
Culture Yield

Blood from a two day old male baby with history of respiratory distress and meconium aspiration was sent to the Department of Microbiology for culture. Blood culture yield non haemolytic small colonies of 1-2 mm on Blood agar and no growth on MacConkey agar.Based upon the colony characteristics, biochemical reactions, antimicrobial susceptibility pattern and identification by conventional and Vitek 2 Compact system, the isolate was identified as Elizabethkingia meningoseptica which is a rare cause of bacteremia in neonates.

scholarly journals Pregnancy outcome in women with previous preeclampsia versus women normotensive in previous pregnancy

2018 ◽  
Vol 7 (12) ◽  
pp. 5045
Author(s):  
Jayshree Mulik ◽  
Snehalata Suresh
Keyword(s):  
Pregnancy Outcome ◽  
Perinatal Outcome ◽  
Tertiary Care ◽  
Subsequent Pregnancy ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Previous Pregnancy ◽  
Index Pregnancy ◽  
History Of ◽  
Adverse Pregnancy

Background: Women with history of preeclampsia have reportedly higher risk of development of preeclampsia in subsequent pregnancies, along with other adverse pregnancy outcomes. Authors aimed to study the incidence of recurrent preeclampsia and compare the pregnancy outcome in women with history of preeclampsia in previous pregnancy with those who were normotensive in previous pregnancy and further compare outcomes in women with recurrent preeclampsia between their previous and index pregnancy.Methods: Pregnancy outcome was studied in women with preeclampsia in previous pregnancy (cases) and compared with women normotensive in previous pregnancy (controls). Further analysis of cases was done by dividing them into subgroups: those with recurrent preeclampsia in index pregnancy (A1) and those normotensive in index pregnancy despite being pre-eclamptic in previous pregnancy (A2). Total 100 cases and 100 controls were enrolled in the study, which was conducted at present tertiary care centre from January 2012 to June 2013.Results: Out of total 200 participants (100 cases, 100 controls) enrolled in the study; 58 out of 100 cases had recurrent preeclampsia and remaining 42 remained normo-tensive in index pregnancy. Among 100 controls, 93 were normotensive in index pregnancy.Conclusions: Women with history of preeclampsia in previous pregnancy had adverse maternal and perinatal outcome in subsequent pregnancy when compared to the women who were normotensive in the previous pregnancy. But when compared with their own previous preeclamptic pregnancy, they had better pregnancy outcome with good perinatal outcome in their index pregnancy. 

scholarly journals Incidence of steroid modified tinea in tertiary care centre Lucknow

2018 ◽  
Vol 4 (4) ◽  
pp. 579
Author(s):  
Savita Chaudhary ◽  
Priyanka Shukla ◽  
Khushboo Gupta ◽  
Gaurav Paliwal
Keyword(s):  
Tertiary Care ◽  
Common Species ◽  
Topical Steroids ◽  
Age Group ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Detailed History ◽  
Microbiological Profile ◽  
History Of ◽  
Common Variety

<p class="abstract"><strong>Background:</strong> Rampant use and abuse of topical steroids has led to increase in number of cases of superficial dermatophytosis of skin, nail and hair. In most of the cases they are resistant to topical as well as oral antifungals even after prolong course of treatment. Our study aims to analyse epidemiological and microbiological profile of steroid modified tinea (SMT).</p><p class="abstract"><strong>Methods:</strong> Clinically diagnosed tinea patients with history of usage of topical steroids were included in our study. Detailed history was taken and clinical examination along with KOH mount and culture was done.<strong></strong></p><p class="abstract"><strong>Results:</strong> 980 patients were screened of which 550 patients with history of using topical steroids were included in our study. Most common age group was 20 to 29 years with male: female of ratio approximately 3:1 and disseminated form was the most common variety. KOH mount was positive in 76% cases and culture was positive in 72% cases. Most common species came out to be <em>T. Mentagrophytes</em> followed by <em>T. rubrum</em>. Among non-dermatophyte group, Candida was the commonest.</p><p class="abstract"><strong>Conclusions:</strong> There is<strong> </strong>rise in incidence of dermatophytosis, especially steroid modified one and cases of disseminated tinea are rising.</p>

scholarly journals Effect of treatment on the quality of life of cervical cancer patients: a prospective study from a tertiary care centre of West Bengal

2019 ◽  
Vol 7 (1) ◽  
pp. 300
Author(s):  
Manisha Sarkar
Keyword(s):  
Quality Of Life ◽  
Cervical Cancer ◽  
Cancer Patients ◽  
West Bengal ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Financial Difficulties ◽  
History Of

Background: Cervical cancer is one of many health care ironies. Better survival rates demand better quality of life (QoL). The aim of present study was to determine the change in QoL of cervical cancer patients due to treatment.Methods: An observational prospective study was conducted from July 2017 to June 2018 among 80 new cervical cancer patients without any prior history of treatment for cervical cancer, attending radiotherapy department of a tertiary care centre of West Bengal using a semi-structured schedule and European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire (QLQ). Information was collected on socio-demographic and clinical aspects and QoL domains. Those with history of surgery for cervical cancer, advanced stage of disease were excluded. EORTC QLQ was administered at baseline and one month after completion of treatment. Data was analysed by percentage, means±standard deviation, range and Wilcoxon signed rank test etc. using SPSS-16.Results: Only 60 patients could be analysed as 10 patients died and 10 lost to follow-up. After treatment there was a significant improvement in global health, physical, emotional and cognitive functioning as well as decrease in symptoms like fatigue, pain, insomnia, appetite loss and constipation along with worsening of financial difficulties. There was significant improvement in body image, decrease in problems of symptom experience, peripheral neuropathy and menopausal symptoms after treatment.Conclusions: The cervical cancer patients show an overall improvement in their QoL in most of the domains after one month of treatment except worsening of financial difficulties. 

Clinical characteristics of children presenting with history of sexual abuse to a tertiary care centre in India

2016 ◽  
Vol 19 ◽  
pp. 44-49 ◽  
Author(s):  
Bhaskaran T.S. Sowmya ◽  
Shekhar P. Seshadri ◽  
Shoba Srinath ◽  
Satish Girimaji ◽  
John Vijay Sagar
Keyword(s):  
Sexual Abuse ◽  
Clinical Characteristics ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
History Of

scholarly journals Screening for Hearing Impairment in High-Risk Neonates in a Tertiary Care Centre in Central Kerala

2020 ◽  
Vol 7 (49) ◽  
pp. 2959-2963
Author(s):  
Maina J ◽  
Rati Santhakumar ◽  
Manoj V.C. ◽  
Mridula Vellore
Keyword(s):  
Risk Factors ◽  
High Risk ◽  
Hearing Impairment ◽  
Otoacoustic Emissions ◽  
Tertiary Care ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Auditory Rehabilitation ◽  
History Of ◽  
Evoked Response Audiometry

BACKGROUND Hearing loss is a chronic condition, and many cases can be detected in the neonatal period. Recognizing it early is of crucial importance as early auditory rehabilitation would help in child’s comprehensive development. We wanted to assess the prevalence of hearing impairment among high risk newborns admitted to inborn unit of tertiary care centre in Central Kerala and screen for the associated risk factors in these newborns. METHODS Thousand consecutive inborn neonates from Neonatal ICU, Department of Paediatrics, tertiary care centre in Thrissur, Kerala, detected as high risk by Joint Committee on Infant Hearing (JCIH) criteria were enrolled for the study from December 2011 to November 2012 after the approval by Institute’s Ethics Review Board. Risk factor assessment was done before enrolment. A qualified audiologist conducted the test on babies in soundproof chamber. DPOAEs (Distortion Product Otoacoustic Emissions) were used for initial testing after checking ears for debris. Those who failed in the first test were asked to come for a retest after 2 weeks. Those who failed in the retest were asked to report for Brainstem Evoked Response Audiometry (BERA). Those who were diagnosed as having hearing impairment were advised auditory rehabilitation as well as auditory verbal therapy. RESULTS Of the 1000 eligible neonates born in our hospital during the study period (December 2011 to November 2012) 69 were lost to follow up. Among the remaining 931 babies the frequency of hearing impairment was 0.8 %. Among the 931 neonates, 130 had absent response with the first OAE test contributing to 13.9 %. Twenty-one neonates had absent response to second OAE test out of 130 contributing to 16.1 %. The failure rate for second test is 2.2 % of the total population of 931 newborns. Eight of the 21 neonates who were subjected to BERA had severe hearing loss. The prevalence of hearing impairment was 8 per 1000. CONCLUSIONS The prevalence (percentage) of hearing impairment by two staged screening protocol is 0.8 %. Risk factors which were present in these babies were prematurity, low birth weight, low Apgar score, history of exanthematous fever in mother, neonatal jaundice, ototoxic medication history, craniofacial anomalies, and family history of deafness, meningitis and mechanical ventilation. KEYWORDS Otoacoustic Emissions, Brain Stem Evoked Response Audiometry, Risk Factors, Hearing Impairment, Neonates

scholarly journals Adverse drug reaction profile at psychiatry outpatient department of a tertiary care centre

2017 ◽  
Vol 6 (10) ◽  
pp. 2428
Author(s):  
Ujwala P. Gawali ◽  
Harshad V. Kesari ◽  
Komal S. Gawand
Keyword(s):  
Tertiary Care ◽  
Outpatient Department ◽  
Uppsala Monitoring Centre ◽  
Care Hospital ◽  
Causality Analysis ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
Monitoring Centre ◽  
History Of ◽  
Reaction Profile

Background: Monitoring adverse drug reactions (ADRs) helps in alerting physicians and developing strategies to prevent and minimize the risk of developing ADRs. Data regarding pattern of ADRs due to psychotropic medications is scanty. Hence, the study was planned to assess ADRs among psychiatry outpatients of a tertiary care hospital in Maharashtra.Methods: A prospective, observational study was conducted in psychiatry outpatient department of a tertiary care centre for 3 months. Cases were enrolled by active and passive surveillance after obtaining informed consent. Demographic details, adverse event details, history of medications were recorded. Pattern of ADRs was studied according to demographic parameters, drug class, organ system affected, causality (WHO - Uppsala Monitoring Centre Scale) and severity (modified Hartwig and Siegel Scale).Results: Out of total 1200 patients screened, 77 qualified the inclusion and exclusion criteria and 92 ADRs were reported; overall incidence rate of 6.41%. Maximum ADRs were reported in the age group of 31- 40 years. 63.63% subjects received more than 2 psychotropic drugs. Among 24 types of ADRs observed, tremor (13.04%) was the commonest, closely followed by somnolence. Antipsychotics (45.65%) were most frequently incriminated and central nervous system (46.73%) the most often affected. Trifluoperazine (11.96%) was the commonest drug, followed by olanzapine and haloperidol (10.53% each). Causality analysis yielded 66 ADRs as “probable” and on severity analysis 80.43% were mild.Conclusions: The study provides an insight into pattern of ADRs in psychiatry outpatients. It is prudent to communicate this to treating physicians as well as counsel patients (and caregivers). Initiatives and concerted efforts involving all stakeholders in healthcare can go a long way in decreasing drug-related morbidity and health costs.

scholarly journals Study of risk factors of acute respiratory infections in children admitted in a tertiary care hospital of Southern Maharashtra

2017 ◽  
Vol 4 (9) ◽  
pp. 3129
Author(s):  
Alka C. Kaware ◽  
Nitin H. Kamble ◽  
S. K. Mangulikar
Keyword(s):  
Risk Factors ◽  
Respiratory Infections ◽  
Tertiary Care ◽  
High Morbidity ◽  
Acute Respiratory Infections ◽  
Care Hospital ◽  
Care Centre ◽  
Tertiary Care Centre ◽  
History Of ◽  
Tract Infections

Background: Acute respiratory infections (ARI) is an important cause of mortality and morbidity in children. In India, it constitutes 15% of under five deaths. Various risk factors are responsible for ARI in children. Study of risk factors will help to reduce the high morbidity and mortality due to ARI. The objectives were to study risk factors responsible for acute respiratory infections in children and to find out case fatality rate &/ outcome of acute respiratory infections ARI in children.Methods: A hospital based cross sectional study was done in 2013-14 in a tertiary care centre to study the risk factors associated with ARI in children. All the pediatric patients between 0-12 years admitted in a tertiary care centre at Solapur were enrolled in the study.Results: Acute respiratory tract infections (ARI) were more common in 1-4 years age group i.e. 57.31% (196). It was more common in males i.e. 64.33% (220) than females i.e. 35.67% (122). ARI was more common in lower socio-economic classes i.e. class V (50.58%), class IV (22.52%); in patients whose mothers were illiterate 43.28% and who had history of parental smoking 84.21%. Maximum patients of ARI were having history of overcrowding 75.73%, inadequate cross-ventilation 81.87% and use of smoky chullah 78.65% in their home. Statistically significant association found between ARI cases and these socio-demographic factors. 46.78% (160) were incompletely immunized and 16.37% (56) were not immunized at all. Only 36.84% (126) were completely immunized for their age. Maximum cases of ARI (50.88%) occurred in winter season followed by rainy season (26.90%). Outcome showed that 91.52% (313) were cured, while 1.75% (6) patients died due to ARI.Conclusions: The present study has identified various socio-demographic, nutritional and environmental risk factors for ARI which can be prevented by effective health education and an appropriate initiative taken by the government.

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