scholarly journals Genotype screening of Cannabis sativa L. based on the specifics of minor cannabinoids manifestation

2021 ◽  
Vol 17 (3) ◽  
pp. 218-225
Author(s):  
S. V. Mishchenko ◽  
H. I. Kyrychenko ◽  
I. М. Laiko

Analysis of hemp collection samples based on the content of minor (rare) non-psychotropic cannabinoids, such as cannabichromene (CBC), cannabidivarin (CBDV), and cannabinol (CBN); determination of correlation relationships between them and common compounds; selection of valuable breeding genotypes. Methods. Field, biochemical (gas chromatography of cannabinoid compounds), and statistical (pair, partial, and multiple linear correlations). Results. Quantitative analysis of 210 samp­les of various ecological-geographical and genetic origin (local and wild forms, self-filing lines, hybrids, varieties, synthetic populations, polyploids) with a tetrahydrocannabinol (THC) content of less than 0.08% in dried plants showed the level of manifestation of the trait from its absence within the sensitivity of the gas chromatograph up to 0.6838% CBC, 0.1719% CBC and 0.3274% CBN. In the studied hemp samples, a medium negative relationship was found between the signs of the CBC and cannabidiol (CBD) contents (r = –0.53), a weak negative relationship between CBC and CBDV contents (r = –0.35), medium positive relationships between the signs of CBC and THC contents (r = 0.57) and CBC and CBN contents (r = 0.59). A medium positive correlation (r = 0.57) was found between the signs of CBDV and CBD contents, while CBN had a strong positive relationship with THC (r = 0.82). There is almost no correlation between cannabigerol (CBG) and the minor cannabinoids under study. The biosynthesis of minor cannabinoid compounds is quite complex. Signs manifestation is affected by many genetic and external factors. Partial correlation coefficients (given that one of the three signs is eliminated) and multiple correlation coefficients (given that the relationship of one sign is determined and two other signs are combined) give grounds to state that the gene for CBCA-synthase affects the production of CBD and, in particular THC. Conclusions. The closeness of the linear relationships between minor cannabinoids and common components allows selecting valuable hemp samples with a high content of one or several compounds under the absence or low content of psychotropic THC.

2019 ◽  
Vol 34 (2) ◽  
pp. 367-382
Author(s):  
Irsa Fatima Makhdoom ◽  
Mohsin Atta ◽  
Najma Iqbal Malik

The present study was an endeavor to extend the literature of perceived organizational politics by examining its moderating role between the relationship of organizational citizenship behavior and production deviance. Organizational Citizenship Behavior Scale (Mackenzie, Podsakoff, & Paine, 1999), Production Deviance sub-scale of Counterproductive Work Behavior Checklist-32 (Spector et al., 2006), and Perception of Organizational Politics Scale (Kacmar & Carlson, 1997) were used in present study. Hierarchical regression analyses revealed that low levels of perceived organizational politics moderated the relationship between courtesy and production deviance by strengthening the negative relationship of these behaviors while perceived organizational politics did not act as a moderator for the relationship of civic virtue and conscientiousness with production deviance. High level of go-along-to-get-ahead as a moderator strengthened the relationship of civic virtue and conscientiousness with production deviance and its low level was found to be moderating the relationship between courtesy and production deviance. Future implications of the study were also discussed.


2021 ◽  
pp. 107385842110304
Author(s):  
Lorenzo Lucherini Angeletti ◽  
Andrea Scalabrini ◽  
Valdo Ricca ◽  
Georg Northoff

Social anxiety disorder (SAD) is characterized by social anxiety/fear, self-attention, and interoception. Functional magnetic resonance imaging studies demonstrate increased activity during symptom-sensitive tasks in regions of the default-mode network (DMN), amygdala (AMG), and salience network (SN). What is the source of this task-unspecific symptom-sensitive hyperactivity in DMN? We address this question by probing SAD resting state (rs) changes in DMN including their relation to other regions as possible source of task-unspecific hyperactivity in the same regions. Our findings show the following: (1) rs-hypoconnectivity within-DMN regions; (2) rs-hyperconnectivity between DMN and AMG/SN; (3) task-evoked hyperactivity in the abnormal rs-regions of DMN and AMG/SN during different symptom-sensitive tasks; (4) negative relationship of rest and task changes in especially anterior DMN regions as their rs-hypoconnectivity is accompanied by task-unspecific hyperactivity; (5) abnormal top-down/bottom-up modulation between anterior DMN regions and AMG during rest and task. Findings demonstrate that rs-hypoconnectivity among DMN regions is negatively related to task-unspecific hyperactivity in DMN and AMG/SN. We propose a model of “Topography of the Anxious Self” in SAD (TAS-SAD). Abnormal DMN-AMG/SN topography during rest, as trait feature of an “unstable social self”, is abnormally aggravated during SAD-sensitive situations resulting in task-related hyperactivity in the same regions with an “anxious self” as state feature.


2021 ◽  
pp. JFCP-19-00022
Author(s):  
Kyoung Tae Kim ◽  
Sherman D. Hanna ◽  
Dongyue Ying

The Survey of Consumer Finances (SCF) has included a 4-level risk tolerance measure since 1983. In 2016, the SCF also included an 11-level risk tolerance measure. We compare the two measures, and develop suggestions for using the new measure. While the new measure is seemingly simpler than the old measure, we demonstrate that it does not have a monotonic relationship with owning stock assets, with a pattern similar to the relationship of the old measure to stock ownership. We also identify complex patterns of factors related to different levels of the new measure, for instance education has a negative relationship at one level but positive at another level. Those using the new measure should consider the complex patterns we demonstrate.


2018 ◽  
Vol 203 ◽  
pp. 01003
Author(s):  
Raidan Maqtan ◽  
Badronnisa Yusuf ◽  
Saiful Bahri Hamzah

many of the post tsunami field surveys which conducted by researchers revealed that, the failure due to scour at the landward toe of the seawall due to overtopping of tsunami wave forms one of the important types of coastal defence structures failure and constitutes one of the biggest threats to their structural performance. This study was intended to investigates the scour profile induced by tsunami bores at the landward toe of the vertical seawall and to discuss the effects of the parameters; tide level, incident bore Froude number Fb, incident bore height Hb, overtopping flow Froude number Fo, and overtopping flow depth Ho on the maximum scour depth induced at the landward toe of the seawall. A set of laboratory experiments were conducted at National Hydraulic Research Institute of Malaysia (NAHRIM) with the tichnique of dam break to generate the bore like tsunami. The experiments showed that the initial water level upstream of the seawall has a significant effect on the scour profile and there is a strong negative relationship exists with Froude number of the incident bore and a strong positive relationship exists with Froude number of the overtopping flow depth above the crest of the seawall.


2017 ◽  
Vol 13 (7) ◽  
pp. 69
Author(s):  
Pasit Leeniva ◽  
Prapatpong Upala

The objectives of this research are to evaluate acoustic environments and to forecast STI values from spatial component variables in the large classrooms of the Thai public university that were specially controlled the same room finishing materials including the floor, walls, and ceiling. Whereas the five spatial component factors included (1) Room Volume (RV), (2) Ceiling Height (CH), (3) the Ratio of Depth to Width (Rdw), (4) Total Room Surface (TS), and (5) Percentage of Absorbing Surface areas (PAS). The research tools were the smartphones that used the applications for acoustical evaluation and speech intelligibility analysis. The Speech Transmission Index (STI), Reverberation Time (RT), and Background Noise Level (BNL) were collected by the calibrated microphone in the nine points distributed across the entire room. And also, the sounds for testing were simulated such as balloon burst, and STIPA signal via a sound generator. The Thailand Speech Intelligibility (T-SI) model was developed by the multiple regression analysis with a statistical at a confidence level of 95%.The results showed that this T-SI model depended on the strongly positive relationship of PAS and the slightly positive relationship of CH, TS while the RV, Rdw were slightly the negative relationship and which predicted STI values. Moreover, the highest affecting variable of T-SI model was CH and the lowest was PAS. However, this research implies that the improving room acoustic quality would be adjusting the sound absorbing surface areas i.e., increase the cloth curtain or appropriate methods.


2009 ◽  
Vol 44 (2) ◽  
pp. 190-196 ◽  
Author(s):  
Jessica M. Walter ◽  
Bonnie L. Van Lunen ◽  
Stacy E. Walker ◽  
Zahra C. Ismaeli ◽  
James A. Oñate

Abstract Context: Athletic training education program directors (ATEPDs) often manage their time among students, program administration, and patient care. Objective: To assess the level of burnout in ATEPDs and to determine the relationship between burnout and various demographics of ATEPDs. Design: Cross-sectional study. Setting: Public and private colleges and universities nationwide. Patients or Other Participants: Two hundred forty-nine ATEPDs of undergraduate athletic training education programs accredited by the Commission on Accreditation of Athletic Training Education. Intervention(s): We administered the Maslach Burnout Inventory (MBI) to all participants. Main Outcome Measure(s): The MBI consisted of 21 items assessing 3 characteristics of burnout: emotional exhaustion, depersonalization, and personal accomplishment. Another component of the survey requested demographic information about the ATEPDs. We used univariate, multivariate, and factorial analyses of variance with the α level set a priori at .05. We also calculated Pearson product moment correlation coefficients. Results: Women had greater emotional exhaustion than men (20.67 ± 9.43 and 16.47 ± 9.64, respectively) (P  =  .001). The difference between tenure-status groups for emotional exhaustion was significant (P  =  .014), with tenure-track ATEPDs scoring higher on emotional exhaustion than tenured ATEPDs. Pearson product moment correlation coefficients revealed a weak negative relationship among emotional exhaustion and age (r  =  −0.263, P < .001), years of program director experience (r  =  −0.157, P  =  .013), and years at current job (r  =  −0.162, P  =  .010), indicating that as ATEPDs aged, gained more experience, and stayed in their current jobs, their emotional exhaustion scores decreased. There was also a weak negative relationship between age and depersonalization (r  =  −0.171, P  =  .007). There was a weak positive relationship between years at current job and personal accomplishment (r  =  0.197, P  =  .002). Conclusions: We found that ATEPDs experienced a moderate form of emotional exhaustion burnout and low depersonalization and personal accomplishment burnout, with women experiencing greater emotional exhaustion than males. Additionally, ATEPDs in tenure-track positions experienced greater emotional exhaustion than tenured ATEPDs. The ATEPDs need to obtain healthy coping strategies early within their directorships to manage components related to burnout.


Author(s):  
Fernando S. Rodrigo

The combined influence of the North Atlantic Oscillation (NAO) and the East Atlantic (EA) patterns on the covariability of temperatures and precipitation in 35 stations of the Iberian Peninsula during the period 1950-2019 is analysed in this work. Four EA-NAO composites were defined from teleconnection patterns positive and negative phases: EA+NAO+, EA+NAO-, EA-NAO+, and EA-NAO-. Daily data of maximum and minimum temperature were used to obtain seasonal means (TX, and TN, respectively), and the covariability of these variables with accumulated seasonal rainfall (R) was studied comparing results obtained for different NAO and EA composites. Main results indicate slight differences in the spatial coverage of correlation coefficients between R and temperature variables, except in spring when the generalized negative relationship between R and TX under EA+NAO+ and EA-NAO- disappears under EA-NAO+ and EA+NAO- composites. This result may be useful to interpret and discuss historical reconstructions of Iberian climate.


2017 ◽  
Vol 4 (3) ◽  
Author(s):  
Dr. Zlatko Šram

The aim of this research was to examine if comorbid relationships exist between psychopathy and depression in a community sample of different ethnic and sex groups. Based on some previous research, it was hypothesized that psychopathy and depression would be correlated and that secondary psychopathy would be the strongest predictor of depression regardless of different ethnic and sex belongings. The survey was carried out on the adult population in the region of Croatia populated by citizens of Croatian and Serbian minority ethnicity. The equalized convenience sample of 1100 participants, half of which were Croats and half of males. Pearson-product moment correlation coefficients were calculated as a measure of the strength and direction of linear relationships among primary and secondary and depression. In order to determine how well scores on depression could be predicted by primary and secondary psychopathy across different demographic groups, multiple regression analysis were used. It was found that both primary and secondary psychopathy were significantly correlated in a positive direction with depression in different ethnic and sex groups. However, secondary psychopathy was more correlated with depression across different ethnic and sex subsamples. The results of regression analysis revealed that secondary psychopathy was the strongest predictor of depression in all demographic subsamples. After age and school attainment were introduced into regression models, it was shown that a very small percentage of the variance is explained by the sociodemographic variables. The research suggested a significant role of secondary psychopathy in relation to a higher level of psychopathology.


2020 ◽  
Vol 24 (1) ◽  
pp. 1
Author(s):  
Rahmat Hidayat, Farah Margaretha Leon

This study aims to analyze the green CSR  of innovation performance  with firms approval variables  and public visibility   can support moderating the relationship of green CSR  and innovation. The research sample was 33 manufacturing companies. The results showed that the  green CSR has a positive and significant effect on innovation . Also, the company approval variable has been proven to moderate the direction of a positive relationship between green CSR and innovation . The results also prove that public visibility is proven to moderate the direction of the negative relationship between green CSR and performance. This study provide information that shows great concern for the environment; it will increase the company in making changes through innovation activities. Also, the higher the company's approval and public visibility, the company will get support from various stakeholders to run the firms. The level of company concern for CSR activities will be a misjudgment for investors.


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