scholarly journals Role of combined mucolytic therapy in infectious and inflammatory diseases of the respiratory system in children

2019 ◽  
pp. 56-59 ◽  
Author(s):  
Yu. L. Mizernitsky ◽  
I. M. Melnikova
Keyword(s):  
Respiratory System ◽  
Respiratory Diseases ◽  
Inflammatory Diseases ◽  
Antibacterial Effects ◽  
Chronic Respiratory Diseases ◽  
Pathogenetic Mechanisms ◽  
Therapeutic Measures

The use of combined medicines simultaneously influencing various pathogenetic mechanisms of inflammation and coughing becomes an essential direction of mucoactive therapy in childhood. One of these is thiamphenicol glycinate acetylcysteinate, which has both mucolytic and antibacterial effects, which significantly expands the possibilities of therapy in bacterial etiology of acute and exacerbation of chronic respiratory diseases, increases the effectiveness of therapeutic measures, improves compliance.

scholarly journals ASSESSMENT OF MORBIDITY AND EFFECTIVENESS OF MEDICAL REHABILITATION OF CHILDREN WITH CHRONIC DISEASES OF THE RESPIRATORY SYSTEM IN CLINIC

2018 ◽  
Vol 24 (6) ◽  
pp. 284-288
Author(s):  
Viktoria V. Polunina ◽  
M. I Dubrovskaya ◽  
A. N Lobov ◽  
V. P Plotnikov ◽  
S. V Pavlova
Keyword(s):  
Chronic Diseases ◽  
Respiratory System ◽  
Respiratory Diseases ◽  
Total Duration ◽  
Average Frequency ◽  
Main Group ◽  
Medical Rehabilitation ◽  
Chronic Respiratory Diseases ◽  
Chronic Morbidity

The data obtained in the study of incidence in children, reflect the results of the children’s clinic. Analysis of the incidence was carried out according to the analysis of medical records. In the structure of general and chronic morbidity in children, the leading places belong to respiratory diseases, among which chronic diseases of adenoids and tonsils prevail (67.7%). Therefore, prevention and timely effective treatment of diseases of the respiratory system will reduce the overall incidence, and, consequently, improve the performance of a children’s clinic. To determine the role of medical rehabilitation, a group of children aged 3 to 14 years with chronic respiratory diseases was recruited in the amount of 127 children (68 boys and 59 girls). In the main group (n=78), treatment without exacerbation included 3 courses of comprehensive medical rehabilitation, including physiotherapy, reflexology, and physical therapy; in the control (n=49) treatment was carried out only in the period of exacerbation. The total duration of observation in both groups was 12 months. The effectiveness of treatment was assessed by the dynamics of the frequency and duration of colds and exacerbations of chronic diseases during the year. In the main group, the average frequency of colds for the year decreased by 2 times (p

scholarly journals Microbiota: A Missing Link in The Pathogenesis of Chronic Lung Inflammatory Diseases

2021 ◽  
Vol 70 (1) ◽  
pp. 25-32
Author(s):  
AGNIESZKA MAGRYŚ
Keyword(s):  
Respiratory Diseases ◽  
Inflammatory Diseases ◽  
Chronic Obstructive ◽  
High Morbidity ◽  
Obstructive Pulmonary Disease ◽  
Chronic Respiratory Diseases ◽  
Chronic Pulmonary Diseases ◽  
Underlying Mechanisms

Chronic respiratory diseases account for high morbidity and mortality, with asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis (CF) being the most prevalent globally. Even though the diseases increase in prevalence, the exact underlying mechanisms have still not been fully understood. Despite their differences in nature, pathophysiologies, and clinical phenotypes, a growing body of evidence indicates that the presence of lung microbiota can shape the pathogenic processes underlying chronic inflammation, typically observed in the course of the diseases. Therefore, the characterization of the lung microbiota may shed new light on the pathogenesis of these diseases. Specifically, in chronic respiratory tract diseases, the human microbiota may contribute to the disease’s development and severity. The present review explores the role of the microbiota in the area of chronic pulmonary diseases, especially COPD, asthma, and CF.

From Genesis To Revelation: The Role Of Inflammatory Mediators In Chronic Respiratory Diseases And Their Control By Nucleic Acid-Based Drugs

2016 ◽  
Vol 13 (999) ◽  
pp. 1-1 ◽  
Author(s):  
Sante Di Gioia ◽  
Carla Sardo ◽  
Stefano Castellani ◽  
Barbara Porsio ◽  
Giuliana Belgiovine ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Inflammatory Mediators ◽  
Respiratory Diseases ◽  
Chronic Respiratory Diseases

Therapeutic role of vegetables in Respiratory Diseases – A critical review from Ayurvedic classics.

2016 ◽  
Vol 1 (3) ◽  
Author(s):  
Dr. Raghavendra Naik ◽  
Shweta Vekariya ◽  
R. N. Acharya ◽  
Sneha D. Borkar
Keyword(s):  
Clinical Practice ◽  
Respiratory Disease ◽  
Respiratory System ◽  
Critical Review ◽  
Critical Analysis ◽  
Respiratory Diseases ◽  
Unique Contribution ◽  
Pharmacological Activities ◽  
The Family

The concept of Pathya (wholesome diet) is an unique contribution of Ayurveda, which plays an important role in prevention and management of many diseases. “Shakavarga”, a category under dietetics in classical texts of Ayurveda enlisted different vegetables with their properties and indications in different disease conditions. These vegetables can be prescribed as Pathya (wholesome diet) in clinical practice. In the present review, plants described under Shakavarga, indicated as Pathya in different diseases related to Pranavaha Srotas (Respiratory system) were compiled from 15 different Ayurvedic classical texts. Critical analysis of the compiled data reveals that out of 332 vegetables described under Shakavarga, 44 are indicated in respiratory disease like Shvasa (Dyspnoea/Asthma), Kasa (Cough), Peenasa (Chronic rhinitis) and Hikka (Hiccup). Among them, botanical identity of 42 classical plants has been established and maximum number of vegetables belongs to the family cucurbitaceae (10) followed by solanaceae (4). Some of these vegetables have been reported for their various pharmacological activities related to prevention and management of diseases related to Pranavaha Srotas (Respiratory system). These vegetables are reported for their anti-inflammatory (16), antioxidant (14), anti-allergic (6) and antitussive (3) activities. The observed result may be helpful in use of vegetables as Pathya (wholesome diet) and planning further scientific studies about the efficacy of these plants on prevention as well as management of respiratory diseases.

scholarly journals IL-33 Mediated Inflammation in Chronic Respiratory Diseases—Understanding the Role of the Member of IL-1 Superfamily

2019 ◽  
Vol 10 ◽  
Author(s):  
Agata Gabryelska ◽  
Piotr Kuna ◽  
Adam Antczak ◽  
Piotr Białasiewicz ◽  
Michał Panek
Keyword(s):  
Respiratory Diseases ◽  
Chronic Respiratory Diseases

scholarly journals Expert recommendations on the role of macrolides in chronic respiratory diseases

Lung India ◽  
2021 ◽  
Vol 38 (2) ◽  
pp. 174
Author(s):  
Raja Dhar ◽  
Deepak Talwar ◽  
Virendra Singh ◽  
Harjit Dumra ◽  
Sujeet Rajan ◽  
...  
Keyword(s):  
Respiratory Diseases ◽  
Chronic Respiratory Diseases ◽  
Expert Recommendations

scholarly journals Conference: "COPD: a social disease: inappropriateness and pharmaco-economics. The role of the specialist: present and future"

2010 ◽  
Vol 5 ◽  
Author(s):  
Claudio F. Donner
Keyword(s):  
Economic Impact ◽  
Respiratory Diseases ◽  
Health Problems ◽  
Major Health ◽  
Chronic Respiratory Diseases ◽  
Employment Sector ◽  
Full Sense ◽  
Socio Economic Impact ◽  
Institutional Network

Chronic respiratory diseases (CRDs), with particular regard to COPD, constitute an epidemic in the full sense of the term, though they still go underdiag- nosed and undertreated. COPD is one of the major health problems worldwide, negatively affecting patients and their families, the employment sector, the institutional network and, hence, society as a whole. Its epidemiological, clinical, social and socio-economic impact is on the rise and there are no signs of any change to this trend. Edited by Claudio F. Donner

scholarly journals Lung Microbiome in Asthma: Current Perspectives

2019 ◽  
Vol 8 (11) ◽  
pp. 1967 ◽  
Author(s):  
Konstantinos Loverdos ◽  
Georgios Bellos ◽  
Louiza Kokolatou ◽  
Ioannis Vasileiadis ◽  
Evangelos Giamarellos ◽  
...  
Keyword(s):  
Respiratory Diseases ◽  
Human Microbiome ◽  
Current Evidence ◽  
Host Immune System ◽  
Prevention Strategies ◽  
Chronic Respiratory Diseases ◽  
Lung Microbiome ◽  
Modes Of Interaction ◽  
Review Current

A growing body of evidence implicates the human microbiome as a potentially influential player actively engaged in shaping the pathogenetic processes underlying the endotypes and phenotypes of chronic respiratory diseases, particularly of the airways. In this article, we specifically review current evidence on the characteristics of lung microbiome, and specifically the bacteriome, the modes of interaction between lung microbiota and host immune system, the role of the “lung–gut axis”, and the functional effects thereof on asthma pathogenesis. We also attempt to explore the possibilities of therapeutic manipulation of the microbiome, aiming at the establishment of asthma prevention strategies and the optimization of asthma treatment.

scholarly journals Role of in Asthma and Nonasthmatic Eosinophilic Bronchitis

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Beatriz Sastre ◽  
Victoria del Pozo
Keyword(s):  
Respiratory Diseases ◽  
Inflammatory Diseases ◽  
Direct Action ◽  
Airflow Obstruction ◽  
Eosinophilic Bronchitis ◽  
Beneficial Effects ◽  
Airway Function ◽  
Smooth Muscle Proliferation ◽  
The Difference

Eosinophilic bronchitis is a common cause of chronic cough, which like asthma is characterized by sputum eosinophilia, but unlike asthma there is no variable airflow obstruction or airway hyperresponsiveness. Several studies suggest that prostaglandins may play an important role in orchestrating interactions between different cells in several inflammatory diseases such as asthma. PGE2is important because of the multiplicity of its effects on immune response in respiratory diseases; however, respiratory system appears to be unique in that PGE2has beneficial effects. We described that the difference in airway function observed in patients with eosinophilic bronchitis and asthma could be due to differences in PGE2production. PGE2present in induced sputum supernatant from NAEB patients decreases BSMC proliferation, probably due to simultaneous stimulation of EP2 and EP4 receptors with inhibitory activity. This protective effect of PGE2may not only be the result of a direct action exerted on airway smooth-muscle proliferation but may also be attributable to the other anti-inflammatory actions.

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