scholarly journals Distilasyon Yöntemlerinin, Sürelerinin ve Fraksiyonlarının Kekik (Origanum onites L.) Uçucu Yağ Oranları ve Bileşenleri Üzerine Etkisi

2021 ◽  
pp. 3195-3202
Author(s):  
Ümmü TUĞLU ◽  
Hasan BAYDAR ◽  
Sabri ERBAŞ
Keyword(s):  
Origanum Onites

scholarly journals Nanovesicles Loaded with Origanum onites and Satureja thymbra Essential Oils and Their Activity against Food-Borne Pathogens and Spoilage Microorganisms

Molecules ◽  
2021 ◽  
Vol 26 (8) ◽  
pp. 2124
Author(s):  
Giulia Vanti ◽  
Ekaterina-Michaela Tomou ◽  
Dejan Stojković ◽  
Ana Ćirić ◽  
Anna Rita Bilia ◽  
...  
Keyword(s):  
Essential Oils ◽  
Propylene Glycol ◽  
Antimicrobial Properties ◽  
Spherical Shape ◽  
Food Borne Pathogens ◽  
Food Borne ◽  
Spoilage Microorganisms ◽  
Satureja Thymbra ◽  
Origanum Onites

Food poisoning is a common cause of illness and death in developing countries. Essential oils (EOs) could be effective and safe natural preservatives to prevent and control bacterial contamination of foods. However, their high sensitivity and strong flavor limit their application and biological effectiveness. The aim of this study was firstly the chemical analysis and the antimicrobial evaluation of the EOs of Origanum onites L. and Satureja thymbra L. obtained from Symi island (Greece), and, secondly, the formulation of propylene glycol-nanovesicles loaded with these EOs to improve their antimicrobial properties. The EOs were analyzed by GC-MS and their chemical contents are presented herein. Different nanovesicles were formulated with small average sizes, high homogeneity, and optimal ζ-potential. Microscopic observation confirmed their small and spherical shape. Antibacterial and antifungal activities of the formulated EOs were evaluated against food-borne pathogens and spoilage microorganisms compared to pure EOs. Propylene glycol-nanovesicles loaded with O. onites EO were found to be the most active formulation against all tested strains. Additionally, in vitro studies on the HaCaT cell line showed that nanovesicles encapsulated with EOs had no toxic effect. The present study revealed that both EOs can be used as alternative sanitizers and preservatives in the food industry, and that their formulation in nanovesicles can provide a suitable approach as food-grade delivery system.

scholarly journals Antiprotozoal Activity of Turkish Origanum onites Essential Oil and Its Components

Molecules ◽  
2019 ◽  
Vol 24 (23) ◽  
pp. 4421 ◽  
Author(s):  
Tasdemir ◽  
Kaiser ◽  
Demirci ◽  
Demirci ◽  
Baser
Keyword(s):  
Gas Chromatography ◽  
Essential Oil ◽  
Mammalian Cells ◽  
Leishmania Donovani ◽  
Vitro Activity ◽  
In Vitro Activity ◽  
Flame Ionization ◽  
Main Component ◽  
Origanum Onites

Essential oil of Origanum species is well known for antimicrobial activity, but only a few have been evaluated in narrow spectrum antiprotozoal assays. Herein, we assessed the antiprotozoal potential of Turkish Origanum onites L. oil and its major constituents against a panel of parasitic protozoa. The essential oil was obtained by hydrodistillation from the dried herbal parts of O. onites and analyzed by Gas Chromatography-Flame Ionization Detector (GC-FID) and Gas Chromatography coupled with Mass Spectrometry (GC-MS). The in vitro activity of the oil and its major components were evaluated against Trypanosoma brucei rhodesiense, T. cruzi, Leishmania donovani, and Plasmodium falciparum. The main component of the oil was identified as carvacrol (70.6%), followed by linalool (9.7%), p-cymene (7%), γ-terpinene (2.1%), and thymol (1.8%). The oil showed significant in vitro activity against T. b. rhodesiense (IC50 180 ng/mL), and moderate antileishmanial and antiplasmodial effects, without toxicity to mammalian cells. Carvacrol, thymol, and 10 additional abundant oil constituents were tested against the same panel; carvacrol and thymol retained the oil’s in vitro antiparasitic potency. In the T. b. brucei mouse model, thymol, but not carvacrol, extended the mean survival of animals. This study indicates the potential of the essential oil of O. onites and its constituents in the treatment of protozoal infections.

scholarly journals Extraction, Chemical Composition, and Anticancer Potential of Origanum onites L. Essential Oil

Molecules ◽  
2019 ◽  
Vol 24 (14) ◽  
pp. 2612 ◽  
Author(s):  
Katerina Spyridopoulou ◽  
Eleni Fitsiou ◽  
Eleni Bouloukosta ◽  
Angeliki Tiptiri-Kourpeti ◽  
Manolis Vamvakias ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Cell Lines ◽  
Cancer Cell ◽  
Antiproliferative Activity ◽  
Biological Activities ◽  
Colorectal Cancer Cell Line ◽  
Ht 29 ◽  
Origanum Onites

Origanum species are plants rich in volatile oils that are mainly used for culinary purposes. In recent years, there has been a growing interest in the biological activities of their essential oils. Origanum onites L. is a plant mainly found in Greece, Turkey, and Sicily, whose oil is rich in carvacrol, a highly bioactive phytochemical. The aim of this study was to analyze the chemical composition of Origanum onites essential oil (OOEO), and investigate its potential anticancer effects in vitro and in vivo. GC/MS analysis identified carvacrol as OOEO’s main constituent. In vitro antiproliferative activity was assayed with the sulforhodamine B (SRB) assay against human cancer cell lines from four tumor types. HT-29, a colorectal cancer cell line, was the most sensitive to the antiproliferative activity of OOEO. Wound-healing assay and Annexin V-PI staining were employed to investigate the antimigratory and the pro-apoptotic potential of OOEO, respectively, against human (HT-29) and murine (CT26) colon cancer cells. Notably, OOEO attenuated migration and induced apoptosis-related morphological changes in both cell lines. Prophylactic oral administration of the oil in a BALB/c experimental mouse model inhibited the growth of syngeneic CT26 colon tumors. As far as we know, this is the first report on the antitumor potential of orally administered OOEO.

scholarly journals Relation between leaf area and dimensions of selected medicinal plants

2012 ◽  
Vol 51 (No. 1) ◽  
pp. 13-19 ◽  
Author(s):  
C. Çırak ◽  
M. S Odabaş ◽  
B. Sağlam ◽  
A. K Ayan
Keyword(s):  
Medicinal Plants ◽  
Leaf Area ◽  
Prediction Models ◽  
Leaf Length ◽  
Urtica Dioica ◽  
Nerium Oleander ◽  
Mentha Piperita ◽  
Black Sea Region ◽  
Package Program ◽  
Origanum Onites

In this research, leaf area prediction models were developed for some leaf-used medicinal plants namely Calamintha nepeta, Datura stromonium, Melissa officinalis, Mentha piperita, Nerium oleander, Origanum onites and Urtica dioica growing wild in Black Sea region of Turkey. Lamina width, length and leaf area were measured non-destructively to develop the models. The actual leaf areas of the plants were measured by PLACOM Digital Planimeter, and multiple regression analysis with Excel 7.0 computer package program was performed for the plants separately. The produced leaf area prediction models in the present study were formulized as LA = (a) + (b<sub>1</sub> &times; L) + [(b<sub>2</sub> &times; (L &times; W)]&nbsp; + (b<sub>3</sub> &times; L<sup>2</sup>) + (b<sub>4</sub> &times; W<sup>2</sup>) + [b<sub>5</sub> &times; (L &times; W<sup>2</sup>)] + [b<sub>6</sub> &times; (L<sup>2</sup> &times; W)] + [b<sub>7</sub> &times; (L<sup>2</sup> &times; W<sup>2</sup>)] where LA&nbsp;is leaf area, W&nbsp;is leaf width, L is leaf length and a, b<sub>1</sub>, b<sub>2</sub>, b<sub>3</sub>, b<sub>4</sub>, b<sub>5</sub>, b<sub>6</sub>, and b<sub>7</sub> are coefficients. R<sup>2</sup> values for medicinal plants tested varied with species from 0.82 in Origanum onites to 0.98 in Urtica dioica. All R&sup2; values and standard errors were found to be significant at the P &lt; 0.001 level.

Origanum onites L.

2012 ◽  
pp. 452-453
Author(s):  
Shakhnoza S. Azimova ◽  
Anna I. Glushenkova
Keyword(s):  
Origanum Onites
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