Impact of Aloe Vera gel aqueous extract-supplemented yogurt on reproductive performance of male rats

Background: Diabetes mellitus can lead to histomorphometrical changes in the brain. Recent studies have shown that Aloe vera gel has antioxidant and neuroprotective effects, which is independent of glucose-lowering effects. Objectives: The present study aimed to investigate the effects of A. vera gel on histomorphometrical changes of cerebellum following streptozotocin (STZ)-induced diabetic male rats. Methods: A total of 25 male Wistar rats were randomly allocated into five groups as follows: (1) the control group received normal saline; (2) A. vera gel group; (3) diabetic group (normal saline); (4) treatment group diabetic rats, which received A. vera; and (5) diabetic rats which received insulin. A single dose of STZ [60 mg/kg; intraperitoneal (IP)] was used for the induction of diabetes in rats. All the treatments were administered daily for eight weeks. Subsequently, histomorphometrical changes were evaluated in the cerebellum of the rats. Results: The results showed that the number of granular and purkinje cells reduced in the cerebellum granulosa region, while the number of glial cells increased in the molecular region of the cerebellum in diabetic rats compared to the control group (P < 0.05). These changes were improved in treated rats by insulin or A. vera. Also, the thickness of molecular, purkinje, granular, and white matter layers at the apex of lobules and depth of sulcus in the diabetic group had a significant reduction compared to other groups (P < 0.001). Conclusions: Our results confirmed that improvement of the cerebellar tissue changes in diabetic rats following the use of A. vera gel is comparable to insulin. However, more investigations are required to determine the protective effects of A. vera gel against diabetes-induced cerebellum histomorphometrical changes.

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Inhibitory Effects of Aloe Vera Gel Aqueous Extract and L. casei Against E. coli in Yoghurt

Journal of Biology and Today s World ◽

10.15412/j.jbtw.01050901 ◽

2016 ◽

Vol 5 (9) ◽

Cited By ~ 1

Author(s):

Z. Nemati Niko ◽

P. Ghajarbeygi ◽

R. Mahmoudi ◽

S. Mousavi ◽

K. Mardani

Keyword(s):

Aqueous Extract ◽

Aloe Vera ◽

Inhibitory Effects ◽

E Coli ◽

Aloe Vera Gel

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Determination of antioxidant potential of biochemically synthesized silver nanoparticles using Aloe vera gel extract

Plant Science Today ◽

10.14719/pst.2019.6.2.532 ◽

2019 ◽

Vol 6 (2) ◽

pp. 208-217 ◽

Cited By ~ 2

Author(s):

Jasmeet Kaur Sohal ◽

Ashish Saraf ◽

Kamlesh Shukla ◽

Meghna Shrivastava

Keyword(s):

Silver Nanoparticles ◽

Aqueous Extract ◽

Average Particle Size ◽

Radical Scavenging ◽

Aloe Vera ◽

Reducing Power ◽

Antioxidant Potential ◽

Average Particle ◽

Aloe Vera Gel ◽

Before And After

Biosynthesis of nanoparticles by using plant extracts is presently under development. The study has been focused on the biosynthesis of silver nanoparticles (AgNPs) using aqueous extract of Aloe vera gel as well as to determine their antioxidant potential. UV-Vis spectrophotometeric analysis showed surface plasmonic resonance (SPR) band at 440 nm, which is specific for AgNPs. The Transmission Electron Microscopy (TEM) revealed that the synthesized AgNPs were spherical in shape with an average particle size of 66.6 nm. Fourier Transform Infrared Spectroscopic (FTIR) analysis of the aqueous extract before and after the synthesis of AgNPs revealed the presence of different functional groups related to phenolic and polyphenolic compounds such as tannins and flavonoids, and other metabolites like proteins, which may be responsible for the synthesis and stabilization of AgNPs. The antioxidant potential of the synthesized AGAgNPs was determined by using 2, 2 Diphenyl-1- Picryl Hydrazyl (DPPH) radical scavenging, metal chelating and reducing power assay. Antioxidant assessment showed enhanced dose dependent antioxidant potential of the synthesized AgNPs as compared to the crude extract, which can gain attention of the pharmaceutical industry for preparation of antioxidants of natural origin as the synthetic ones are suspected to be carcinogenic. Present study also supports the advantages of green method for the nanoparticles synthesis.

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Effect of Aloe vera Gel Administrated on Reproductive Performance of Female Rats

Jurnal Kedokteran Hewan - Indonesian Journal of Veterinary Sciences ◽

10.21157/j.ked.hewan.v1i1.3101 ◽

2007 ◽

Vol 1 (1) ◽

Author(s):

Gunawan G ◽

Enny T Setiatin ◽

Bayu Rosadi ◽

Thomas Mata Hine ◽

A. Parakkasi

Keyword(s):

Body Weight ◽

Corpus Luteum ◽

Reproductive Performance ◽

Body Weight Gain ◽

Aloe Vera ◽

The Body ◽

Female Rats ◽

Aloe Vera Gel ◽

Per Oral ◽

Average Body

The research was conducted to find out the effect of Aloe vera gel administrated orally onreproductive performance of female rats. Fifteen two months old female rats were alloted to fivetreatments of per oral Aloe vera gel administration: P0 (control), P1(1 mg /g body weight), P2 (2 mg/gbody weight, P3 (3 mg/g body weight), and P4 ( 4 mg/g body weight). The gel were administrated everyday for four weeks. The body weight were measured on the same day as last treatment. The animal thenmated to proven male on 1:1 rasio. Positively mated animals were sacrificed on D-10 after mating tocollect uterus and ovary so the number of fetus, corpus luteum, and ovary weight can be determined. Thetreatments significantly decreased (P0.05) the average body weight gain. The P0 (4.1 g/head/day) wasdifferent to P1 (2.69 g/head/day), P2 (2.87 g/head/day, and P4 (2.68 g/head/day), but was not different toP3 (3.39 g/head/day). The ovarium weight were not different (P0.05) among the treatments, so did thenumber of corpus luteum (CL), the number of fetuses and the CL: fetus rasio.Keywords: Aloe vera, rats, reproductive performance .

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