A New Approach for the Analysis of Mixture Toxicity Data

1992 ◽  
Vol 26 (9-11) ◽  
pp. 2345-2348 ◽  
Author(s):  
C. N. Haas

A new method for the quantitative analysis of multiple toxicity data is described and illustrated using a data set on metal exposure to copepods. Positive interactions are observed for Ni-Pb and Pb-Cr, with weak negative interactions observed for Ni-Cr.

Geophysics ◽  
2018 ◽  
Vol 83 (6) ◽  
pp. D203-D215
Author(s):  
Zhentao Yang ◽  
Xinding Fang ◽  
L. Huang

We have developed a robust and reliable method for determining borehole shape from six-arm caliper logs. Four- and six-arm calipers are the common caliper tools used in open-hole logging. They provide information about wellbore geometry that is important in petrophysical and geomechanical analyses. The analysis procedure for four-arm caliper logs is well-established, but the analysis for six-arm caliper logs can be troublesome in complex hole environments containing breakouts or keyseats when the tool is off center. The challenge with the six-arm caliper is how to remove the effect of tool decentralization, which cannot be handled properly by using conventional correction methods, which are developed based on the assumption of circular or elliptical boreholes. To resolve this issue, we have developed a new approach for tool decentralization correction. The new method is based on an assumption that the true borehole center should be the center of a circle that fits the caliper pad positions in the least-squares sense subjected to the restriction that the circle is confined within the six pads. We first compare the new method with the conventional chord method and ellipse-fitting method through numerical modeling. We numerically investigate the general performance of these three methods by using a Monte Carlo approach to generate a large number of simulations that mimic caliper logging run in boreholes with a variety of different wellbore geometry. We then study the applicability of the new method in field data analysis by applying it to a field logging data set acquired in a well that contains the breakout and the keyseat. The modeling and field-data results indicate that the new method can yield more reliable estimates of the virgin borehole center than the other two methods and thus can give clearer delineation of the borehole shape.


Author(s):  
Fred L. Bookstein

AbstractA matrix manipulation new to the quantitative study of develomental stability reveals unexpected morphometric patterns in a classic data set of landmark-based calvarial growth. There are implications for evolutionary studies. Among organismal biology’s fundamental postulates is the assumption that most aspects of any higher animal’s growth trajectories are dynamically stable, resilient against the types of small but functionally pertinent transient perturbations that may have originated in genotype, morphogenesis, or ecophenotypy. We need an operationalization of this axiom for landmark data sets arising from longitudinal data designs. The present paper introduces a multivariate approach toward that goal: a method for identification and interpretation of patterns of dynamical stability in longitudinally collected landmark data. The new method is based in an application of eigenanalysis unfamiliar to most organismal biologists: analysis of a covariance matrix of Boas coordinates (Procrustes coordinates without the size standardization) against their changes over time. These eigenanalyses may yield complex eigenvalues and eigenvectors (terms involving $$i=\sqrt{-1}$$ i = - 1 ); the paper carefully explains how these are to be scattered, gridded, and interpreted by their real and imaginary canonical vectors. For the Vilmann neurocranial octagons, the classic morphometric data set used as the running example here, there result new empirical findings that offer a pattern analysis of the ways perturbations of growth are attenuated or otherwise modified over the course of developmental time. The main finding, dominance of a generalized version of dynamical stability (negative autoregressions, as announced by the negative real parts of their eigenvalues, often combined with shearing and rotation in a helpful canonical plane), is surprising in its strength and consistency. A closing discussion explores some implications of this novel pattern analysis of growth regulation. It differs in many respects from the usual way covariance matrices are wielded in geometric morphometrics, differences relevant to a variety of study designs for comparisons of development across species.


Symmetry ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 726
Author(s):  
Lamya A. Baharith ◽  
Wedad H. Aljuhani

This article presents a new method for generating distributions. This method combines two techniques—the transformed—transformer and alpha power transformation approaches—allowing for tremendous flexibility in the resulting distributions. The new approach is applied to introduce the alpha power Weibull—exponential distribution. The density of this distribution can take asymmetric and near-symmetric shapes. Various asymmetric shapes, such as decreasing, increasing, L-shaped, near-symmetrical, and right-skewed shapes, are observed for the related failure rate function, making it more tractable for many modeling applications. Some significant mathematical features of the suggested distribution are determined. Estimates of the unknown parameters of the proposed distribution are obtained using the maximum likelihood method. Furthermore, some numerical studies were carried out, in order to evaluate the estimation performance. Three practical datasets are considered to analyze the usefulness and flexibility of the introduced distribution. The proposed alpha power Weibull–exponential distribution can outperform other well-known distributions, showing its great adaptability in the context of real data analysis.


The Analyst ◽  
2020 ◽  
Vol 145 (11) ◽  
pp. 3909-3915 ◽  
Author(s):  
Xu Wu ◽  
Liping Wang ◽  
Yan Peng ◽  
Fang Wu ◽  
Jiumei Cao ◽  
...  

A new method for the qualitative and quantitative detection of direct oral anticoagulant rivaroxaban by terahertz spectroscopy.


2013 ◽  
Vol 321-324 ◽  
pp. 1947-1950
Author(s):  
Lei Gu ◽  
Xian Ling Lu

In the initialization of the traditional k-harmonic means clustering, the initial centers are generated randomly and its number is equal to the number of clusters. Although the k-harmonic means clustering is insensitive to the initial centers, this initialization method cannot improve clustering performance. In this paper, a novel k-harmonic means clustering based on multiple initial centers is proposed. The number of the initial centers is more than the number of clusters in this new method. The new method with multiple initial centers can divide the whole data set into multiple groups and combine these groups into the final solution. Experiments show that the presented algorithm can increase the better clustering accuracies than the traditional k-means and k-harmonic methods.


1992 ◽  
Vol 101 (1) ◽  
pp. 51-60 ◽  
Author(s):  
Eiji Yanagisawa ◽  
Ken Yanagisawa ◽  
Jay B. Horowitz ◽  
Lawrence J. Mambrino

A new approach to microlaryngeal surgery using a specially designed video microlaryngoscope with a rigid endoscopic telescope and an attached video camera was introduced by Kantor et al in 1990. The ability to video document and perform surgery of the larynx by viewing a high-resolution television image was demonstrated. This method was recommended over the standard microscopic technique for increased visibility with greater depth of field, unimpeded instrument access, instant documentation, and superior teaching value. The authors tried this new method and the standard microscopic technique at the same sitting on a series of patients. This paper will compare these two different techniques and discuss their advantages and disadvantages. Although the new method has many advantages, the standard microscopic technique remains as a valuable method in laryngeal surgery.


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