RISK FACTORS PROFILE FOR MYOCARDIAL INFARCTION: FOCUS AT A YOUNG AGE

The paper focuses on examining peculiarities of risk factors causing cardiac infarction at a young age. Although car- diac infarction primarily occurs among patients older than 45, its frequency at a young age has been growing recently. Risk factors that cause cardiac infarction at a young and old age are quite different. Examining risk factors profiles in different age groups provides wider opportunities for implementing primary and secondary prevention strategies aimed at reducing frequency and negative outcomes of ischemic heart disease.108 patients aged from 18 to 45 and 35 patients aged from 60 to 75 took part in the research; they all had confirmed cardiac infarction with or without rise in ST segment and were treated in a regional center for cardiovascular pathology treatment in a period from January 01, 2017 to January 01, 2019. Basic risk factors of cardiac infarction were assessed when a patient was admitted to a clinic for treatment. The research results indicate high prevalence of risk factors that could cause ischemic heart disease among young pa- tients. 92.2 % young patients have dyslipidemia, 70.2 % smoke, 68.5 have low physical activity, 68.2 % suffer from over- weight and obesity, 58.8 % have arterial hypertension, 7.4 % suffer from type II pancreatic diabetes, and disorders in toler- ance to carbohydrates was reveled in 15.7 % cases. Such factors as male sex (85.2 vs. 37.1 %, р=0,000), smoking (70.2 vs. 20.6 %, р=0.000) and burdened heredity as per early ischemic heart disease occurrence (54.6 vs. 16.0 %, р=0.001) were significantly more frequent among young patients than among older ones. Data obtained via the present research allowed creating risk factors profile for cardiac infarction associated with car- diac infarction occurrence at a young age; this profile included such factors as male sex, early ischemic heart disease occur- rence in family history, and smoking

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RISK FACTORS PROFILE FOR MYOCARDIAL INFARCTION: FOCUS AT A YOUNG AGE

Health Risk Analysis ◽

10.21668/health.risk/2021.3.16 ◽

2021 ◽

pp. 160-166

Author(s):

I.A. Novikova ◽

◽

O.V. Khlynova ◽

L.A. Nekrutenko ◽

◽

...

Keyword(s):

Risk Factors ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Age Groups ◽

Young Patients ◽

Young Age ◽

Ischemic Heart ◽

Cardiac Infarction ◽

Regional Center ◽

Male Sex

The paper focuses on examining peculiarities of risk factors causing cardiac infarction at a young age. Although car- diac infarction primarily occurs among patients older than 45, its frequency at a young age has been growing recently. Risk factors that cause cardiac infarction at a young and old age are quite different. Examining risk factors profiles in different age groups provides wider opportunities for implementing primary and secondary prevention strategies aimed at reducing frequency and negative outcomes of ischemic heart disease. 108 patients aged from 18 to 45 and 35 patients aged from 60 to 75 took part in the research; they all had confirmed cardiac infarction with or without rise in ST segment and were treated in a regional center for cardiovascular pathology treatment in a period from January 01, 2017 to January 01, 2019. Basic risk factors of cardiac infarction were assessed when a patient was admitted to a clinic for treatment. The research results indicate high prevalence of risk factors that could cause ischemic heart disease among young pa- tients. 92.2 % young patients have dyslipidemia, 70.2 % smoke, 68.5 have low physical activity, 68.2 % suffer from over- weight and obesity, 58.8 % have arterial hypertension, 7.4 % suffer from type II pancreatic diabetes, and disorders in toler- ance to carbohydrates was reveled in 15.7 % cases. Such factors as male sex (85.2 vs. 37.1 %, р=0,000), smoking (70.2 vs. 20.6 %, р=0.000) and burdened heredity as per early ischemic heart disease occurrence (54.6 vs. 16.0 %, р=0.001) were significantly more frequent among young patients than among older ones. Data obtained via the present research allowed creating risk factors profile for cardiac infarction associated with car- diac infarction occurrence at a young age; this profile included such factors as male sex, early ischemic heart disease occur- rence in family history, and smoking

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Risk Factors for Ischemic Heart Disease (IHD) Among Young and Old Age Groups Patients of District Peshawar

LIAQUAT MEDICAL RESEARCH JOURNAL ◽

10.38106/lmrj.2019.1.2-01 ◽

2019 ◽

Vol 1 (2) ◽

pp. 24-26

Author(s):

Faria Maqsood

Keyword(s):

Risk Factors ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Old Age ◽

Age Groups ◽

Ischemic Heart

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Ischemic Heart Disease in Subjects of Young Age: Current State of the Problem. Features of Etiology, Clinical Manifestation and Prognosis

Kardiologiia ◽

10.18087/cardio.2018.11.10195 ◽

2018 ◽

Vol 58 (11) ◽

pp. 24-34 ◽

Cited By ~ 2

Author(s):

E. Yu. Andreenko ◽

I. S. Yavelov ◽

М. М. Loukianov ◽

A. N. Vernohaeva ◽

O. M. Drapkina ◽

...

Keyword(s):

Risk Factors ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Molecular Genetic ◽

Young Patients ◽

Ischemic Heart ◽

Coronary Syndrome ◽

Current State ◽

Monogenic Diseases ◽

Conventional Risk Factors

In addition to conventional risk factors in young patients with ischemic heart disease (IHD) numerous other risk factors including genetics play an important role in its causation. Molecular genetic testing is recommended for the detection of monogenic diseases with a high risk of developing IHD, such as familial hypercholesterolemia. In majority ofyoung patients, the first manifestation of IHD is an acute coronary syndrome. Young patients with IHD more often have normal coronary arteries or single-vessel coronary disease, and in up to 20% of them cause of myocardial ischemia is not related to atherosclerosis. In general, young patients with IHD have better prognosis. However, there are sex differences in IHD outcomes the prognosis of patients with premature IHD and reason for this is still unclear.

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Evaluation of Ischemic Heart Disease in the Young Population of Georgia

European Scientific Journal ESJ ◽

10.19044/esj.2021.v17n18p33 ◽

2021 ◽

Vol 17 (18) ◽

Author(s):

Gogishvili Giorgi

Keyword(s):

Risk Factors ◽

Heart Disease ◽

Young People ◽

Ischemic Heart Disease ◽

Night Shift ◽

Young Patients ◽

Female Gender ◽

Ischemic Heart ◽

Control Group ◽

Ischemic Disease

Objective: Study of risk factors (RF) for ischemic heart disease (IHD) in young people is a significant problem in cardiology. Aims: Study and prognosis of ischemic heart disease in Georgian population under 45 years of age. Methods: The study included 107 young patients with coronary heart disease (from 18 to 44 years old), who were treated in the cardiology department of the St. John the Merciful Private Clinic. The average age was (34.68 ± 6.2) years. The control group consisted of 199 healthy volunteers without cardiovascular diseases at the age from 18 to 44 years, the average age was (35.9 ± 5.2) years. In all patients, traditional risk factors were assessed. Results: Regression analysis has shown that it increases the risk of ischemic heart disease: living in the city - OR=6.90(95%CI:1.28-37.18); sleep disturbance - OR=45.62(95%CI:3.52-590.64); obesity -OR=24.56(95%CI:4.14-145.66); hypertension - OR=40.76(95%CI:8.07-205.92); excess intake of saturated fats - OR=79.94(95%CI:10.93-584.43); night shift - OR=39.01(95%CI:3.75-405.75); early detection of ischemic disease in grade I-II relatives - OR=44.22(95%CI:8.07-242.17); decrease - female gender - OR=0.14 (95%CI:0.03-0.70) and married - OR=0.01(95%CI:0.00-0.08); Conclusion: The ability to predict the risk of developing IHD in young people on the basis of traditional RFs, most of which are modifiable, as well as the study of "new" RFs opens up new perspectives in the formation of a strategic approach to the management of young patients in the presence of high risk.

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