scholarly journals Inflammatory Myofibroblastic Tumor of Common Bile Duct in a Girl

2016 ◽  
Vol 7 (4) ◽  
pp. 28 ◽  
Author(s):  
Aureen Ruby DCunha ◽  
Susan Jehangir Homi ◽  
Reju Joseph Thomas

Inflammatory myofibroblastic tumor (IMT) is a rare, low grade malignant lesion which can occur anywhere in the body. It children it is usually found in the visceral soft tissues with a potential for local invasion and recurrence, and rarely distant metastasis. We report the diagnostic dilemma faced in the management of a 12-year old girl who presented with obstructive jaundice with a mass lesion at the distal end of the common bile duct. She underwent a tumor resection with a bilio-enteric bypass followed by a course of oral steroids and celecoxib.

2009 ◽  
Vol 42 (1) ◽  
pp. 43-48
Author(s):  
Hidenori Kusumoto ◽  
Tsunekazu Mizushima ◽  
Toshikazu Ito ◽  
Hitoshi Mizuno ◽  
Yuko Udatsu ◽  
...  

2021 ◽  
Vol 9 (4) ◽  
pp. 73-75

The maleficent tumour granulocytic sarcoma is an unusual cancer indite of progressive myeloid precursor cells. It is a Chloroma basically present at an extramedullary location spread through immature granulocytic cells. It can affect any part of the body but the primary site is soft tissues, outside bone marrow, lymph nodes. The root cause may be many factors i.e. genetic, environmental, carcinogens etc. This proliferative type of cancer is sometimes misdiagnosis in contradictory to other acute/chronic tumours. For a histopathologist, it is a challenge for an accurate diagnosis. The tissue biopsy is the known diagnostic technique used since days in cancer diagnosis. To address this review, our main focus is to investigate, analyse the diagnostic limitations or research gaps in granulocytic sarcoma recognition at the clinical level and what can be the possibilities that have developed recently in tumour detection at an early stage. Next, we will try to develop a hypothesis from pinpoint methods used in it as molecular diagnosis, immune-histochemical biomarkers, flow cytometry (FACS) for confirmation of sarcoma so that specificity and sensitivity can be well examined. The prognosis/diagnosis in myeloid tumour detection depends on key factor innovation and medical devices and that should be filled in research and so a gold standard diagnostic kit should be developed.


Author(s):  
Raja Sekhar Gali

AbstractA plethora of pathologies occurs in the skeletal and soft tissues of the oro-facial region that are reactive. These arise as a result of chronic low-grade inflammation, trauma, hormonal influence and other causes. Varied types of clinical, radiological and histological presentations are often associated with these lesions that pose a diagnostic dilemma to the clinician. This chapter describes in detail the common reactive lesions of the maxillofacial region with an emphasis on correlating the clinical and investigational findings to arrive at the correct diagnosis and provide appropriate treatment.


Author(s):  
Christine U. Lee ◽  
James F. Glockner

51-year-old man with possible cholangiocarcinoma MIP image from 3D FRFSE MRCP (Figure 4.1.1) demonstrates that the main pancreatic duct drains into the duodenum at the minor papilla, separate from the common bile duct. Pancreas divisum Pancreas divisum is the most common pancreatic developmental anomaly, with an estimated prevalence of 4% to 15%. It occurs when the ducts of the dorsal and ventral pancreatic buds fail to fuse. This results in the main pancreatic duct draining into the duodenum at the minor papilla via the duct of Santorini, separate from the common bile duct, which drains into the major papilla. (With normal development, the ventral duct of Wirsung fuses with the main pancreatic duct of the body and tail and drains into the major papilla with the common bile duct.)...


Inflammatory myofibroblastic tumor (IMT) is a rare occurrence most commonly affecting the pediatric population. It is considered a diagnostic challenge because of nonspecific clinical symptoms and radiologic presentations. IMT is a soft-tissue tumor that can occur throughout the body but is most commonly found in the lung. This article discusses the case of a 10-year-old girl who presented to our hospital with abnormal chest radiograph. Imaging revealed a heterogenous mass in the superior aspect of the left lower lobe. It was found incidentally when the patient presented to the emergency department. Surgical resection proved a diagnostic and therapeutic measure confirming diagnosis of IMT. The tumor has potential to cause illness either by its rare malignant potential or by mass effect. Because lesions are often asymptomatic with a predilection for pediatric patients, cases describing appropriate management are essential. IMT is a rare tumor of borderline malignant potential. IMT of the lung may invade hilar structures, the mediastinum, and the pleura. Lesions range in diameter from 1.5 to 14 cm. Etiology of the tumor is unclear but may include immune response to infection, trauma, or surgery. Affected patients may present with cough and shortness of breath but are often asymptomatic. Histology is unique but not specific. Immunohistochemistry can differentiate the tumor, by staining for overexpression of the anaplastic lymphoma kinase oncogene. In conclusion, surgical resection is the preferred diagnostic and therapeutic regimen for IMT. The majority of IMTs follow a benign course, but exceptions qualify as low-grade malignancies. As a result, it is important to identify, treat, and maintain vigilance. This case encompasses presentation, diagnosis, and treatment of pulmonary IMT and highlights best practices in addressing IMT for adolescent patients.


Metallomics ◽  
2019 ◽  
Vol 11 (6) ◽  
pp. 1093-1103 ◽  
Author(s):  
Marta Costas-Rodríguez ◽  
Sanne Van Campenhout ◽  
Agustina A. M. B. Hastuti ◽  
Lindsey Devisscher ◽  
Hans Van Vlierberghe ◽  
...  

The effect of cholestatic liver disease on the body Cu isotopic distribution was investigated in a common bile duct ligation mouse model. The isotopic composition of Cu in serum and organs becomes gradually lighter with increasing severity of the disease.


2021 ◽  
Vol 11 ◽  
pp. 28
Author(s):  
Mohamed Tarek El-Diasty ◽  
Mohammad Abdelrahim Wazzan ◽  
Ahmed Haitham Abduljabbar

A 43-year-old man presented with painless jaundice. Imaging revealed a porta hepatis mass compressing the common bile duct. Endoscopic biopsy was negative for malignancy. Complete surgical resection was performed. Pathological assessment showed IGg4 negative inflammatory myofibroblastic tumor.


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