Functional Disability Among Systemic Sclerosis Patients: Relation to Disease Characteristics and Quality of Life Parameters

2021 ◽  
Vol 17 ◽  
Author(s):  
Rabab S. Zaghlol ◽  
Ghada A. Dawa ◽  
Wafaa K. Makarm
Keyword(s):  
Quality Of Life ◽  
Functional Disability ◽  
Short Form ◽  
Management Strategies ◽  
Bodily Pain ◽  
Health Assessment ◽  
Clinical Findings ◽  
Cross Sectional ◽  
Sf 36

Background: Disability in patients with scleroderma (SSc) has been associated with poor health-related quality of life (HRQoL) in all dimensions, including physical, psychological, and social dimensions. Objective: This study was conducted to examine different factors that may be associated with functional disability and poor HRQoL, with the aim of targeting these factors in the future to improve physical activity, functional outcomes, and HRQoL. Methods: A single-center cross-sectional study was conducted on 38 patients with SSc to compare characteristics between patients with and without disability using the Health Assessment Questionnaire Disability Index (HAQ-DI). Quality of life was assessed using the Short Form–36 (SF-36). Linear regressions were performed to examine variables contributing to functional disability. Results: Almost 65.78% (n = 25) of patients in the study group reported functional disability. The presence of functional disability was associated with reduced HRQoL, as reflected by physical function (P = 0.0001), physical role (P = 0.016), bodily pain (P = 0.001), general health (P = 0.002), social functional (P = 0.002), emotional role (P = 0.042), and mental health (P = 0.025) domains of the SF-36 score. Multiple linear regression indicated that the main predictive factors associated with HAQ-DI were the modified Hand Mobility in Scleroderma; modified Rodnan skin score; DIstance walked in 6 minutes, BOrg dyspnea index, and SAturation of oxygen at 6 minutes (DIBOSA); and Fatigue Severity Scale among patients with SSc. Conclusion: In patients with SSc, recognizing the relationships between clinical findings and functional disability will allow the development of further management strategies to minimize disease severity and enhance HRQoL.

scholarly journals Quality of Life among Patients with Glaucoma in Gaza Governorates

2020 ◽  
Vol 28 (1) ◽  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Bodily Pain ◽  
Cross Sectional Study ◽  
Negative Effects ◽  
Cross Sectional ◽  
Sf 36 ◽  
Medium Level ◽  
Ophthalmic Hospital

Background: Glaucoma is the second leading cause of blindness worldwide. Quality of Life (QOL) has emerged as an important parameter for assessing the quality of health care of patients with Glaucoma disease. This study assessed QOL among Glaucoma patients in Gaza Governorates and the factors influencing their life conditions. Methods: This is a descriptive, analytical, cross-sectional study included 265 eligible glaucoma patients from Al Nasser Ophthalmic Hospital and European Gaza Hospital. Socio-demographic and disease-related characteristics in addition to QOL data were collected using the Glaucoma Quality of Life-15 (GQL-15) and Short-Form 36 Health Survey (SF-36) questionnaires. Results: Study participants had a medium level of QOL scores. The mean score for GQL-15 was 59.2 ± 17.6. The greatest difficulty was in activities involving glare and dark adaptation (48.5±18.0), while least difficulty for outdoor mobility (66.6±25.4). The overall mean percentage of SF-36 domain scores was 61.7±13.5. The bodily pain domain got the highest score (79.4); the social function domain was (72.22); and the lowest domain was General Health (48.58). Findings also showed that participants without ocular diseases and comorbidities had better QOL. Moreover, patients with higher educational level, higher income and disease duration less than 5 years had better QOL scores. Conclusion: Glaucoma has moderately negative effects on people’s ability to function independently in every field of their lives. Glaucoma patients should be educated to understand the prognosis of the disease and importance of the adherence to the daily treatment to improve their QOL.

scholarly journals Changes in the health status and functional outcomes in acute traumatic hand injury patients, during physical therapy treatment

2011 ◽  
Vol 44 (02) ◽  
pp. 362-367
Author(s):  
Rebecca John ◽  
Chhaya V. Verma
Keyword(s):  
Quality Of Life ◽  
Physical Therapy ◽  
Functional Disability ◽  
Short Form ◽  
Bodily Pain ◽  
Hand Injury ◽  
Self Report ◽  
Sf 36 ◽  
Traumatic Hand Injury

ABSTRACT Introduction: Traumatic hand injury causes chronic disability. A large number of studies have reported impairments in clinical parameters, but few studies have described their disability experience. Aims To examine the functional disability and quality of life in traumatic hand injured patients receiving physical therapy. Settings and Design: The physiotherapy department in a multi-specialty public sector hospital. Convenient sampling method was used. Materials and Methods: The 36-item short-form health survey–MOS (SF-36, v2) and disabilities of arm, shoulder and hand (DASH) questionnaire were obtained and subjects were given physiotherapy, accordingly to their condition. Questionnaires were re-administered every month till discharge. Statistical Analysis Used: A One-way ANOVA test. Results: At end of 6 months, among eight subscales of SF-36, there is improvement in mean scores of physical functioning (39.1%). The bodily pain, general health, vitality, social function, and mental health had more than 100% improvement. DASH showed regression in disability (50.8%). Conclusions: Measuring quality of life (QOL) can provide detailed assessment of physical disability and treatment effects as well as the global impact of those effects on the person's daily life. Hence, the use of self-report questionnaires such as DASH and SF-36, combined with physical performance score, helps to achieve more comprehensive evaluation of outcome.

scholarly journals QUALITY OF LIFE AFTER PRIMARY PCI IN PAKISTANI POPULATION – DOES IT REALLY CHANGE?

2021 ◽  
Vol 54 (3) ◽  
pp. 224-229
Author(s):  
Rajesh Kumar ◽  
Ali Ammar ◽  
Jehangir Ali Shah ◽  
Tahir Saghir ◽  
Ashok Kumar ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Tertiary Care ◽  
Bodily Pain ◽  
Coronary Intervention ◽  
Cross Sectional Study ◽  
Care Hospital ◽  
Cross Sectional ◽  
Sf 36

Objectives: To evaluate the quality of life (QOL) after percutaneous coronary intervention (PCI) using short-form health survey (SF-36) questionnaire at a tertiary care hospital in Pakistan. Methodology: It was a cross-sectional study conducted at a tertiary care cardiac center in Pakistan. A total of 433 adult patients who undergone PCI at least six months before were included. The QOL was assessed using Urdu translated version of SF-36 questionnaire. QOL scores were computed on eight domains role physical (RP), role emotional (RE), bodily pain (BP), physical function (PF), mental health (MH), vitality, general health perception (GHP), and social function (SF) along with two summary scores for mental (MCS) and physical component (PPS). Results: The highest mean score was reported for BP (73.8±19.7) followed by PF (61.7±24.3). In comparison to a year before, 52.9% and 24.7% rated their QOL somewhat better and much better respectively. Score for PF, RE, and RF were significantly higher in male, while, vitality was higher for female. Score of PPS was significantly higher for male whereas MCS score was higher for female. An increasing trend, with respect to patients’ perception of QOL compared to an year ago, was observed on five out of eight domains namely GHP, PF, RP, RE, and BP. Conclusion: Improved QOL, compared to a year ago, is reported by most of the patients. An acceptable (>50) mean score was observed on most of the QOL domains of SF-36 and it was found to be positively related to the patient stated degrees of QOL.

EVALUATION OF QUALITY OF LIFE IN BRACHIAL PLEXUS INJURY PATIENTS AFTER RECONSTRUCTIVE SURGERY

Hand Surgery ◽  
2006 ◽  
Vol 11 (03) ◽  
pp. 103-107 ◽  
Author(s):  
Izuru Kitajima ◽  
Kazureru Doi ◽  
Yasunori Hattori ◽  
Semih Takka ◽  
Emmanuel Estrella
Keyword(s):  
Quality Of Life ◽  
Brachial Plexus ◽  
Upper Extremity ◽  
Brachial Plexus Injury ◽  
Short Form ◽  
Bodily Pain ◽  
Summary Score ◽  
Joint Function ◽  
Sf 36

To evaluate the subjective satisfaction of brachial plexus injury (BPI) patients after surgery based on the medical outcomes study 36-item short form health survey (SF-36) and to correlate their SF-36 scores with upper extremity functions. Four items were assessed statistically for 30 patients: SF-36 scores after BPI surgery were compared with Japanese standard scores; the correlation between SF-36 scores and objective joint functions; difference in SF-36 scores between each type of BPI; and influence of each joint function on the SF-36 scores. The SF-36 subscale: PF — physical functioning, RP — role-physical, BP — bodily pain, and the summary score PCS — physical component summary, were significantly inferior to the Japanese standard scores. SF-36 is more sensitive to shoulder joint function than to elbow and finger joint functions. Little correlation was found between SF-36 scores and objective evaluations of joint functions. Greater effort is needed to improve the quality of life (QOL) of BPI patients. This study showed that SF-36 is not sensitive enough to evaluate regional conditions. A region- or site-specific questionnaire is required to evaluate upper extremity surgery.

scholarly journals Predictors of quality of life among patients on dialysis in southern Brazil

2008 ◽  
Vol 126 (5) ◽  
pp. 252-256 ◽  
Author(s):  
Maristela Bohlke ◽  
Diego Leite Nunes ◽  
Stela Scaglioni Marini ◽  
Cleison Kitamura ◽  
Marcia Andrade ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Peritoneal Dialysis ◽  
Short Form ◽  
Outcome Measurement ◽  
Cross Sectional Study ◽  
Southern Brazil ◽  
Cross Sectional ◽  
Sf 36 ◽  
Dialysis Facilities

CONTEXT AND OBJECTIVE: Quality of life (QoL) is considered important as an outcome measurement, especially for long-term diseases such as chronic renal failure. The present study searched for predictors of QoL in a sample of patients undergoing dialysis in southern Brazil. DESIGN AND SETTING: This was a cross-sectional study developed in three southern Brazilian dialysis facilities. METHODS: Health-related QoL of patients on hemodialysis or peritoneal dialysis was measured using the generic Short Form-36 (SF-36) health survey questionnaire. The results were correlated with sociodemographic, clinical and laboratory variables. The analysis was adjusted through multiple linear regression. RESULTS: A total of 140 patients were assessed: 94 on hemodialysis and 46 on peritoneal dialysis. The mean age was 54.2 ± 15.4 years, 48% were men and 76% were white. The predictors of higher (better) physical component summary in SF-36 were: younger age (β-0.16; 95% confidence interval, CI: -0.27 to -0.05), shorter time on dialysis (β-0.06; 95% CI: -0.09 to -0.02) and lower Khan comorbidity-age index (β 5.16; 95% CI: 1.7-8.6). The predictors of higher mental component summary were: being employed (β 8.4; 95% CI: 1.7-15.1), being married or having a marriage-like relationship (β 4.56; 95% CI: 0.9-8.2), being on peritoneal dialysis (β 4.9; 95% CI: 0.9-8.8) and not having high blood pressure (β 3.9; 95% CI: 0.3-7.6). CONCLUSIONS: Age, comorbidity and length of time on dialysis were the main predictors of physical QoL, whereas socioeconomic issues especially determined mental QoL.

scholarly journals Health-related quality-of-life assessment in patients with low back pain using SF-36 questionnaire

Medicina ◽  
2007 ◽  
Vol 43 (8) ◽  
pp. 607 ◽  
Author(s):  
Kotryna Vereščiagina ◽  
Kazys Ambrozaitis ◽  
Bronius Špakauskas
Keyword(s):  
Quality Of Life ◽  
Low Back Pain ◽  
Short Form ◽  
Bodily Pain ◽  
Low Back ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Objective. For complete assessment of benefits of the surgical intervention, it is essential to provide evidence of the impact on patients in terms of health status and healthrelated quality of life. In the present study, the preoperative 36-item Short Form (SF-36) Health Survey scores were determined in patients before lumbar microdiscectomy due to better preoperative screening likewise in the control group – almost healthy population taken into account any habitual ailments experienced in an appropriate age. Patients and methods. In the present study, we investigated a cohort of 100 patients with disc herniation causing low back pain and another hundred of the control subjects, matched by age and gender. The short form 36 general health questionnaire (SF-36) was applied. Results. Estimation of the SF-36 scores showed that (1) all of the domain values were considerably lower in the preoperative patient group than in the second one (P<0.01); (2) the bodily pain scores were closely correlated to the social function scores (R=0.7, P<0.01), whereas the physical function was less related to the bodily pain (R=0.6, P<0.01). The weakest correlation was observed between bodily pain and mental health and general health (R=0.4, P<0.01). Conclusion. The present study showed that the generic instrument, SF-36 Health Survey, was optimized paraclinical method for patients predisposed to surgical treatment of the lumbar disc herniation disease likewise for normal population individuals, matched by age and sex, in the assessment of health-related quality of life.

scholarly journals In active acromegaly, IGF1 bioactivity is related to soluble Klotho levels and quality of life

2014 ◽  
Vol 3 (2) ◽  
pp. 85-92 ◽  
Author(s):  
A J Varewijck ◽  
A J van der Lely ◽  
S J C M M Neggers ◽  
S W J Lamberts ◽  
L J Hofland ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Reference Range ◽  
Short Form ◽  
Receptor Activation ◽  
Oral Glucose ◽  
Cross Sectional ◽  
Sf 36 ◽  
Activation Assay ◽  
Active Acromegaly

The value of measuring IGF1 bioactivity in active acromegaly is unknown. Soluble Klotho (S-Klotho) level is elevated in active acromegaly and it has been suggested that S-Klotho can inhibit activation of the IGF1 receptor (IGF1R). A cross-sectional study was carried out in 15 patients with active acromegaly based on clinical presentation, unsuppressed GH during an oral glucose tolerance test, and elevated total IGF1 levels (>+2 s.d.). Total IGF1 was measured by immunoassay, IGF1 bioactivity by the IGF1R kinase receptor activation assay and S-Klotho by an ELISA. Quality of Life (QoL) was assessed by Acromegaly QoL (AcroQoL) Questionnaire and Short-Form-36 Health Survey Questionnaire (SF-36). Out of 15 patients, nine had IGF1 bioactivity values within the reference range. S-Klotho was higher in active acromegaly compared with controls. Age-adjusted S-Klotho was significantly related to IGF1 bioactivity (r=0.75, P=0.002) and to total IGF1 (r=0.62, P=0.02). IGF1 bioactivity and total IGF1 were inversely related to the physical component summary of the SF-36 (r=−0.78, P=0.002 vs r=−0.60, P=0.03). Moreover, IGF1 bioactivity, but not total IGF1, was significantly inversely related to the physical dimension of the AcroQoL Questionnaire (r=−0.60, P=0.02 vs r=−0.37, P=0.19). In contrast to total IGF1, IGF1 bioactivity was within the reference range in a considerable number of subjects with active acromegaly. Elevated S-Klotho levels may have reduced IGF1 bioactivity. Moreover, IGF1 bioactivity was more strongly related to physical measures of QoL than total IGF1, suggesting that IGF1 bioactivity may better reflect physical limitations perceived in active acromegaly.

scholarly journals Childhood mouth-breathing consequences at adult age: ventilatory function and quality of life

2014 ◽  
Vol 27 (2) ◽  
pp. 211-218 ◽  
Author(s):  
Jovana de Moura Milanesi ◽  
Priscila Weber ◽  
Luana Cristina Berwig ◽  
Rodrigo Agne Ritzel ◽  
Ana Maria Toniolo da Silva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Short Form ◽  
Mouth Breathing ◽  
Walk Test ◽  
Ventilatory Function ◽  
Nasal Breathing ◽  
Cross Sectional ◽  
Adult Age ◽  
Sf 36

Introduction Mouth breathing can affect the functions of the respiratory systems and quality of life. For this reason, children who grow up with this stimulus may have implications on physical and psychological aspects at adult age.Objective To evaluate childhood mouth-breathing consequences for the ventilatory function and quality of life at adult age.Materials and methods Prospective, observational and cross-sectional study with 24 adults, between 18 and 30 years old, mouth breathers during childhood, comprised the childhood mouth-breathing group (CMB). The childhood nasal-breathing (CNB) group was composed of 20 adults of the same age, without history of respiratory disease during all their lives. Measurements of maximal respiratory pressures, peak expiratory flow and 6-minute walk test were assessed. In addition, all the volunteers answered the Short Form-36 questionnaire (SF-36).Results The maximal inspiratory (p = 0.001) and expiratory (p = 0.000) pressures as well as the distance in the walk test (p = 0.003) were lower in the COB. The COB also presented lower score in the General Health domain of the SF-36 Questionnaire (p = 0.002).Conclusion Childhood mouth-breathing yields consequences for the ventilatory function at adult age, with lower respiratory muscle strength and functional exercise capacity. Conversely, the quality of life was little affected by the mouth breathing in this study.

scholarly journals Urinary incontinence and quality of life: a systematic review and meta-analysis

2020 ◽  
Author(s):  
Damiano Pizzol ◽  
Jacopo Demurtas ◽  
Stefano Celotto ◽  
Stefania Maggi ◽  
Lee Smith ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Urinary Incontinence ◽  
Short Form ◽  
Meta Analysis ◽  
Case Control ◽  
Case Control Studies ◽  
Cross Sectional ◽  
Sf 36

Abstract Background Urinary incontinence (UI) and low quality of life (QoL) are two common conditions. Some recent literature proposed that these two entities can be associated. However, no attempt was made to collate this literature. Therefore, the aim of this study was to conduct a systematic review and meta-analysis of existing data to estimate the strength of the association between UI and QoL. Methods An electronic search of major databases up to 18th April 2020 was carried out. Meta-analysis of cross-sectional and case–control studies comparing mean values in QoL between patients with UI and controls was performed, reporting random-effects standardized mean differences (SMDs) ± 95% confidence intervals (CIs) as the effect size. Heterogeneity was assessed with the I2. Results Out of 8279 articles initially screened, 23 were finally included for a total of 24,983 participants, mainly women. The mean age was ≥ 50 years in 12/23 studies. UI was significantly associated with poor QoL as assessed by the short-form 36 (SF-36) total score (n = 6 studies; UI: 473 vs. 2971 controls; SMD = − 0.89; 95% CI − 1.3 to − 0.42; I2 = 93.5) and by the sub-scales of SF-36 and 5/8 of the domains included in the SF-36. Similar results were found using other QoL tools. The risk of bias of the studies included was generally high. Conclusions UI is associated with a poor QoL, with a strong level of certainty. This work, however, mainly based on cross-sectional and case–control studies, highlights the necessity of future longitudinal studies for better understanding the importance of UI on QoL.

scholarly journals Predictors of itch and pain in the 12 months following burn injury: results from the Burns Registry of Australia and New Zealand (BRANZ) Long-Term Outcomes Project

2020 ◽  
Vol 8 ◽  
Author(s):  
Lincoln M Tracy ◽  
Dale W Edgar ◽  
Rebecca Schrale ◽  
Heather Cleland ◽  
Belinda J Gabbe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Severe Pain ◽  
Burn Injury ◽  
Short Form ◽  
Bodily Pain ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Abstract Background Itch and pain are common complaints of patients with burn injuries. This study aimed to describe the prevalence and predictors of itch and moderate to severe pain in the first 12 months following a burn injury, and determine the association between itch, moderate to severe pain, work-related outcomes, and health-related quality of life following a burn injury. Methods Burn patients aged 18 years and older were recruited from five Australian specialist burn units. Patients completed the 36-item Short Form Health Survey Version 2 (SF-36 V2), the Sickness Impact Profile (SIP) work scale, and a specially developed questionnaire relating to itch at 1, 6, and 12 months post-injury. Moderate to severe pain was defined as a score less than 40 on the bodily pain domain of the SF-36 V2. Multivariate mixed-effects regression models were used to identify patient and burn injury predictors of itch and moderate to severe pain. Results Three hundred and twenty-eight patients were included. The prevalence of itch decreased from 50% at 1 month to 27% at 12 months. Similarly, the prevalence of moderate to severe pain decreased from 23% at 1 month to 13% at 12 months. Compared to patients aged 18-34, the adjusted odds of experiencing any itch were 59% (95% CI: 0.20, 0.82) and 55% (95% CI: 0.22, 0.91) lower for patients aged between 35 and 49 and ≥ 50 years, respectively. Compared to patients aged 18-34, the adjusted odds of experiencing moderate to severe pain were 3.12 (95% CI: 1.35, 7.20) and 3.42 (95% CI: 1.47, 7.93) times higher for patients aged 35-49 and ≥ 50 years, respectively. Conclusions Less than 15% of patients reported moderate or severe pain at 12 months, while approximately one-quarter of the patients reported itch at the same period. The presence of moderate to severe pain was associated with a greater negative impact on health-related quality of life and work outcomes compared to itch. Further research is needed to improve our ability to identify patients at higher risk of persistent itch and pain who would benefit from targeted review and intervention studies.

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