The neuropharmacological preclinical effects of Nigella Sativa: A review

2021 ◽  
Vol 17 ◽  
Author(s):  
Youness Kadil ◽  
Houda Filali
Keyword(s):  
Experimental Research ◽  
Nigella Sativa ◽  
Present Review ◽  
Google Scholar ◽  
Pharmacological Properties ◽  
Aromatic Plants ◽  
Central Effects ◽  
Research Studies

Background: Many researches papers have demonstrated that Nigella has neurotropic properties, and it has also been shown that Nigella seeds have several activities, such as analgesic, antiepileptic, anxiolytic, antidepressant, and psychostimulant activities. Methods: Databases such as PubMed, Science Direct, Scopus, and Google Scholar were used. Results : The orientation towards this type of research has become more and more accentuated to enhance and detail the pharmacological properties of medicinal aromatic plants. Conclusion : The present review consists in revealing and combining the experimental research studies carried out to demonstrate the central effects of nigella.

scholarly journals Pharmacological effects of Sapindus mukorossi

2012 ◽  
Vol 54 (5) ◽  
pp. 273-280 ◽  
Author(s):  
Aparna Upadhyay ◽  
D.K. Singh
Keyword(s):  
Medicinal Plant ◽  
Present Review ◽  
Pharmacological Properties ◽  
Pharmacological Effects ◽  
Tropical Regions ◽  
Multipurpose Tree ◽  
Phytochemical Composition ◽  
Anti Inflammatory ◽  
Different Parts ◽  
Research Studies

Sapindus mukorossi is an extremely valuable medicinal plant, distributed in tropical and sub-tropical regions of Asia. The aim of present review is to form a short compilation of the phytochemical composition and pharmacological properties of this multipurpose tree. The main phytoconstituents isolated and identified from different parts of this plant are triterpenoidal saponins of oleanane, dammarane and tirucullane type. The structure and chemical names of all the types of triterpenoidal saponins reported in Sapindus mukorossi are included in this review. Many research studies have been conducted to prove the plant's potential as being spermicidal, contraceptive, hepatoprotective, emetic, anti-inflammatory and anti-protozoal. The present review highlights some of the salient pharmacological uses of Sapindus mukorossi.

A Brief Review on the Development of Novel Potentially Active Azetidin-2-ones Against Cancer

2020 ◽  
Vol 24 (5) ◽  
pp. 473-486 ◽  
Author(s):  
Ligia S. da Silveira Pinto ◽  
Thatyana R. Alves Vasconcelos ◽  
Claudia Regina B. Gomes ◽  
Marcus Vinícius N. de Souza
Keyword(s):  
Side Effects ◽  
Anticancer Agents ◽  
Heterocyclic Compounds ◽  
Biological Activities ◽  
Present Review ◽  
Pharmacological Properties ◽  
Important Group ◽  
Wide Range ◽  
Anti Inflammatory

Azetidin-2-ones (β-lactams) and its derivatives are an important group of heterocyclic compounds that exhibit a wide range of pharmacological properties such as antibacterial, anticancer, anti-diabetic, anti-inflammatory and anticonvulsant. Efforts have been made over the years to develop novel congeners with superior biological activities and minimal potential for undesirable side effects. The present review aimed to highlight some recent discoveries (2013-2019) on the development of novel azetidin-2-one-based compounds as potential anticancer agents.

Review of the Essential Oil Composition of Iranian Endemic and Native Taxa of Apiaceae (Umbelliferae)

2020 ◽  
Vol 24 (9) ◽  
pp. 909-1009
Author(s):  
Maryam Akaberi ◽  
Zahra Tayarani-Najaran ◽  
Iraj Mehregan ◽  
Javad Asili ◽  
Amirhossein Sahebkar ◽  
...  
Keyword(s):  
Essential Oil ◽  
Essential Oils ◽  
Essential Oil Composition ◽  
Present Review ◽  
Aromatic Plants ◽  
Oil Composition

One of the most important families of Iranian flora is Apiaceae (Umbelliferae). Most of the species of this family are aromatic plants and rich in essential oils with diverse structures. In the present review, the essential oil composition of 63 genera comprising 141 Apiaceae (66.4% native 33.6% endemic) is summarized.

Google Scholar to identify research studies

2019 ◽  
Author(s):  
Fernando Peralta-Pizza ◽  
David C Pinzón ◽  
Hernando G Gaitán ◽  
Javier Eslava-Schmalbach ◽  
Nelcy Rodriguez-Malagon
Keyword(s):  
Google Scholar ◽  
Research Studies

Therapeutic perspectives of the black cumin component thymoquinone: A review

2021 ◽  
Author(s):  
Chandan Sarkar ◽  
Sarmin Jamaddar ◽  
Tawhida Islam ◽  
Milon Mondal ◽  
Muhammad Torequl Islam ◽  
...  
Keyword(s):  
Therapeutic Potential ◽  
Nigella Sativa ◽  
Pharmacological Properties ◽  
Black Cumin

The dietary phytochemical thymoquinone, obtained from the black and angular seeds of Nigella sativa, is a promising monoterpenoid hydrocarbons, which has been receiving massive attention for its therapeutic potential and pharmacological properties.

scholarly journals Methodology Appraisal of Experimental Research Studies in Mathematics Teaching

2019 ◽  
Vol 5 (1) ◽  
pp. 40-45
Author(s):  
Capote Paul John
Keyword(s):  
Learning Strategies ◽  
Experimental Research ◽  
Teaching And Learning ◽  
Research Problem ◽  
Effect Sizes ◽  
P Value ◽  
Experimental Teaching ◽  
Teaching And Learning Strategies ◽  
The Mean ◽  
Research Studies

This study made use of Gene Glass Effect Size formula to estimate the mean effect sizes of the eleven (11) reviewed experimental research studies on the effect of experimental and conventional teaching and learning strategies to the academic performance of students in mathematics. A validated Inclusion Criteria was utilized in the selection of studies and a modified Methodology Appraisal Checklist was employed in the analysis of elements of the research problem and research methodology. The mean effect sizes and variances of the reviewed studies vary across the elements of the research problem and methodology, an indication that teaching and learning strategies are dependent on the quality of methodology used by the researcher. This study stressed that there is no enough evidence to prove that experimental teaching and learning strategies are more effective than conventional pedagogies in improving learnings in math, as the analysis of variance (ANOVA) revealed a p-value of 0.982 (critical value=0.05).

scholarly journals Oral Microbial Shift: Factors affecting the Microbiome and Prevention of Oral Disease

2016 ◽  
Vol 17 (1) ◽  
pp. 90-96 ◽  
Author(s):  
Kusai Baroudi ◽  
Rushabh Dagli ◽  
Namrata Dagli ◽  
Shrouq Darwish
Keyword(s):  
Industrial Revolution ◽  
Bacterial Species ◽  
The Body ◽  
Oral Microbiome ◽  
Present Review ◽  
Google Scholar ◽  
Oral Disease ◽  
Factors Affecting ◽  
Human Host ◽  
Healthy State

ABSTRACT Background Recently, oral microbiome has gained popularity among scientists. Microorganisms are no longer considered as disease-producing pathogens, rather they are now considered as partners of human in maintaining health. Since ancient times, changes in our lifestyle have affected our microbiome and the balance with their human host has been perturbed. The present review includes the description about factors affecting oral microbiome and establishing symbiosis with the human host so that they contribute in maintaining health rather than eliciting diseases. Materials and methods A comprehensive literature search was performed on databases such as Google Scholar, PubMed and Medline until April 2015. First, articles were selected on the basis of their titles and then abstracts were screened and unwanted articles were excluded. Articles obtained from all the databases were checked and duplicate articles were removed. Articles obtained from various databases: PubMed = 35, Google Scholar = 8. Out of these 43 articles, total 29 articles were finally selected for this review. Results The published literature suggests that the modern oral microbiome is less biodiverse, and possess more pathogenic bacterial species and lesser beneficial bacteria. The possible factors mainly responsible for this shift in microbiome were found to be change in diet, industrial revolution and indiscriminate use of antibiotics. Conclusion Various changes in lifestyles have affected oral microbiome adversely and perturb the symbiosis between the microbiome and their hosts. The present oral microbiome is found to be less diverse and more pathogenic. The present review may be helpful in understanding the relationship between the microbiome and their human hosts so that microbiome contributes in maintaining healthy state of the body. How to cite this article Dagli N, Dagli R, Darwish S, Baroudi K. Oral Microbial Shift: Factors affecting the Microbiome and Prevention of Oral Disease. J Contemp Dent Pract 2016;17(1):90-96.

scholarly journals COVID-19 associated delirium: pathogenetic mechanisms of induction and clinical features

2021 ◽  
Vol 12 (1) ◽  
pp. 33-37
Author(s):  
L. V. Tsoy
Keyword(s):  
Older Adults ◽  
Literature Review ◽  
Clinical Features ◽  
Systematic Literature Review ◽  
Clinical Studies ◽  
Present Review ◽  
Google Scholar ◽  
Pathogenetic Mechanisms ◽  
Potential Factors

The present review describes pathogenetic mechanisms and clinical features of COVID-19 associated delirium. Potential factors leading to the named condition and pathophysiological chains were described elaborately, including older adults’ manifestation analysis based on the latest clinical studies. A systematic literature review was conducted in the following databases: PubMed, Scopus, e-library, Google Scholar and others.

Is Incisura Fibularis a Reliable Landmark for Assessing Syndesmotic Stability? A Systematic Review of Morphometric Studies

2016 ◽  
Vol 10 (3) ◽  
pp. 246-251 ◽  
Author(s):  
Akilesh Anand Prakash
Keyword(s):  
Systematic Review ◽  
Anatomical Landmark ◽  
Present Review ◽  
Google Scholar ◽  
Eligibility Criteria ◽  
Levels Of Evidence ◽  
Wide Variability ◽  
Important Landmark ◽  
Gender Based ◽  
And Gender

Incisura fibularis (IF) is an important landmark in assessing syndesmotic stability radiologically postinjury. The purpose of this review was to explore the anatomy and morphometrics of this widely used anatomical landmark and to further the understanding of the same. A systematic review was conducted online using PubMed and Google Scholar, per PRISMA guidelines. Predefined eligibility criteria were applied, and the data thus compiled were analyzed. Wide variability in morphometrics and, thus, anatomy of IF were observed in the present review, which was influenced by gender. There was no side-to-side variability seen in this study. The study stresses the need to consider the anatomical and gender-based variability while assessing syndesmotic stability and further supports the recommendation of side-to-side comparison. Levels of Evidence: Anatomical, Level V

Internal Validity of Group Experimental Research

1983 ◽  
Vol 4 (3) ◽  
pp. 77-83
Author(s):  
Jean R. Harber
Keyword(s):  
Research Design ◽  
Experimental Research ◽  
Internal Validity ◽  
Experimental Designs ◽  
Causal Relationships ◽  
Control Groups ◽  
Quasi Experimental ◽  
Research Studies

This article stresses the importance of controlling extraneous variables when studying educational problems. Various types of research studies are described. The experimental research design, which is ideally suited to detecting causal relationships if proper controls are used, and quasi-experimental procedures, which are employed when true experimental designs cannot be used, are discussed. Threats to internal validity are presented and hypothetical examples are given to illustrate these threats and the means of controlling them. The importance of utilizing control groups is illustrated.

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