A Comprehensive Review on Pharmacological Properties of Abrus precatorius L.

2020 ◽  
Vol 10 (5) ◽  
pp. 543-549
Author(s):  
Vijay Chopra ◽  
Aishwarya Shriwastva ◽  
Gopal L. Khatik ◽  
Manish Vyas ◽  
Pramod Yadav ◽  
...  
Keyword(s):  
Chemotherapeutic Agent ◽  
Anthelmintic Activity ◽  
Biologically Active ◽  
Pharmacological Properties ◽  
Poisonous Plant ◽  
Comprehensive Review ◽  
Active Constituents ◽  
Abrus Precatorius ◽  
The Family ◽  
Different Parts

Background: Abrus precatorius L. (A. precatorius) is a valuable plant from the family Fabaceae which is a pea family. It is commonly known as Gunja or Jequirity, significantly found throughout India mainly Himalaya to Southern India and Ceylon. It is considered a poisonous plant due to the presence of abrin. Objective: A. precatorius has many pharmacological and biologically active constituents, such as alkaloids, glycosides and flavonoids situated in different parts of the plant. The objective of this review is to provide a retrospective study based on its anticancer potential. Results: Recent studies of A. precatorius are based on the isolation, characterization, and pharmacological evaluation of different secondary metabolites. These constituents possess significant cytotoxic properties against various cancer cell lines including breast, lung, liver, ovarian, prostate and leukaemia. A. precatorius is also reported to have anti-diabetic, anti-microbial, abortifacient, antioxidant, anthelmintic activity, antifertility, nephroprotective, and immunomodulatory activities. Conclusion: The present review summarizes the anticancer potential of A. precatorius and its constituents. However, extensive research is required to establish it as a potent chemotherapeutic agent.

Pharmacological Applications of Saffron (Crocus sativus)

2020 ◽  
pp. 85-92
Author(s):  
Priyanka Singh
Keyword(s):  
Health Management ◽  
Crocus Sativus ◽  
In Vivo Studies ◽  
Pharmacological Properties ◽  
The Family ◽  
Anti Oxidant ◽  
Tumour Activity ◽  
Different Parts

Saffron spice also known as Crocus sativus (Saffron crocus) belongs to the family of iridaceae. Many studies have proved its potential role in disease eradication. It has been reported to possess the attributes of a sedative, an anti-asthma, an emmenagogue, an expectorant, and an adaptogenic agent. Crocin, crocetin, and safranal are the most important biochemically active ingredients that were found in different parts of the plants in varying proportions like the peels, fruits, seeds, and rind of Crocus sativus. The in vitro and in vivo studies showed that saffron has got its therapeutic implication in health management via anti-oxidant, anti-microbial, hepatoprotective, and anti-tumour activity. This review attempts to reveal the potential pharmacological properties of Crocus sativus. It also draws attention towards the use of herbs and spices in various ailments without facing the harmful side effects of chemically derived medicine.

The Genus Glycosmis [Rutaceae]: A Comprehensive Review on its Phytochemical and Pharmacological Perspectives

2019 ◽  
Vol 9 (2) ◽  
pp. 98-124 ◽  
Author(s):  
Mohammad Yasir ◽  
Manish K. Tripathi ◽  
Pushpendra Singh ◽  
Rahul Shrivastava
Keyword(s):  
Complete Information ◽  
Convincing Evidence ◽  
Rich Source ◽  
Biologically Active ◽  
Immunomodulatory Activity ◽  
Anticancer Activities ◽  
Pharmacological Activities ◽  
Lead Compounds ◽  
The Family ◽  
Different Parts

Background:Medicinal plants are rich source of large variety of lead compounds. The plants of genus Glycosmis or its different parts valued for its therapeutic and medicinal qualities. Glycosmis belongs to the family Rutaceae.Objective:The genus Glycosmis is a rich source of pharmacologically and biologically active secondary metabolites, such as alkaloids, flavonoids, phenolic glycosides, quinones, terpenoids, glycerides isolated from different parts of Glycosmis plant. The objectives of this review is to provide updatedand complete information on the distribution, phytochemical, pharmacological, and toxicity research of Glycosmis species.Results:About 233 phytoconstituents are isolated from this genus. Recent interest in this genus has focused on isolating and identifying of different phytoconstituents that exhibit potent antioxidant, antibacterial, antiviral and anticancer activities. They show good cytotoxic activity against various cancer cell lines and also reported for good antiviral and immunomodulatory activity. In this support convincing evidence in experimental animal models are available.Conclusion:This review summarizes information about the isolated compounds their bioactivities related to same compounds present in other plants including pharmacological activities of plant extract of Glycosmis genus.

scholarly journals Potential Antiosteoporotic Agents from Plants: A Comprehensive Review

2012 ◽  
Vol 2012 ◽  
pp. 1-28 ◽  
Author(s):  
Min Jia ◽  
Yan Nie ◽  
Da-Peng Cao ◽  
Yun-Yun Xue ◽  
Jie-Si Wang ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Health Hazard ◽  
Clinical Effectiveness ◽  
Pharmacological Properties ◽  
Medical Systems ◽  
Major Health ◽  
Comprehensive Review ◽  
Active Constituents ◽  
Pharmacological Data ◽  
Future Drug

Osteoporosis is a major health hazard and is a disease of old age; it is a silent epidemic affecting more than 200 million people worldwide in recent years. Based on a large number of chemical and pharmacological research many plants and their compounds have been shown to possess antiosteoporosis activity. This paper reviews the medicinal plants displaying antiosteoporosis properties including their origin, active constituents, and pharmacological data. The plants reported here are the ones which are commonly used in traditional medical systems and have demonstrated clinical effectiveness against osteoporosis. Although many plants have the potential to prevent and treat osteoporosis, so far, only a fraction of these plants have been thoroughly investigated for their physiological and pharmacological properties including their mechanism of action. An attempt should be made to highlight plant species with possible antiosteoporosis properties and they should be investigated further to help with future drug development for treating this disease.

Nutritional and Pharmacological Properties of Bay Leaves (Laurus nobilis L.)

2022 ◽  
pp. 688-697
Author(s):  
Rashmi Srivastava
Keyword(s):  
Mediterranean Region ◽  
Wide Spectrum ◽  
New Drugs ◽  
Pharmacological Properties ◽  
Laurus Nobilis ◽  
The Family ◽  
Pharmacological Studies ◽  
Southern Mediterranean ◽  
Leaf Oil ◽  
Different Parts

Laurus nobilis L., commonly known as bay leaves, is native to the southern Mediterranean region. It is a small tree belonging to the genus Laurus of the family Lauraceae. The essential oils created from the different parts of this plant, such as the leaves and flowers, have been used in the food, drug, and cosmetic industries. The essential oil chiefly consists of 1,8-cineole, sabinene, α-pinene, and p-Cymene. Researchers have reported that bay leaves possess various biological and pharmacological properties, such as antibacterial, antifungal, antioxidant, insecticidal, and nematicidal activities. Pharmacological studies found that bay leaf oil could be a promising candidate with the potential for designing new drugs. The goal of this review is to summarize the ethnomedicinal importance, phytochemistry, and wide spectrum of pharmacological and therapeutic applications of bay leaves, which will be useful to researchers for further study.

scholarly journals Ethnobotanical uses, phytochemistry and biological activities of Clerodendrum paniculatum L. (Lamiaceae): A comprehensive review

2018 ◽  
Vol 8 (5-s) ◽  
pp. 28-34
Author(s):  
T.R. Prashith Kekuda ◽  
S.J. Sudharshan
Keyword(s):  
Biological Activities ◽  
Pharmacological Properties ◽  
Comprehensive Review ◽  
The Family ◽  
Anti Inflammatory ◽  
Ethnobotanical Uses

Clerodendrum L. is an important genus in the family Lamiaceae in terms of its medicinal values and pharmacological properties. The genus comprises of more than 500 species distributed worldwide. In this review, we present an updated information on ethnobotanical uses, phytochemistry and biological activities of Clerodendrum paniculatum L. (Lamiaceae). The plant is one the most spectacular Clerodendrum species and is grown commonly for ornamental purpose. The plant is reported to have ethnomedicinal importance as the plant is used as remedy for ailments and disorders such as wounds, typhoid, snakebite, jaundice, giddiness, malaria, anemia and hemorrhoids. Various phytochemicals such as rutin, quercetin, β-sitosterol, β-amyrin, lupeol, oleanolic aldehyde acetate, stigmasta-4,25-dien-3-one, and (3β)-stigmasta-4,22,25-trien-3-ol have been identified in C. paniculatum. The plant is shown to exhibit biological activities such as antimicrobial, antioxidant, anthelmintic, anti-inflammatory, antimutagenic, cytotoxic, hypolipidemic, insecticidal and anti-ageing activity. Keywords: Clerodendrum paniculatum L., Ethnobotanical, Traditional, Phytochemicals, Biological activities

Nutritional and Pharmacological Properties of Bay Leaves (Laurus nobilis L.)

2020 ◽  
pp. 114-123
Author(s):  
Rashmi Srivastava
Keyword(s):  
Mediterranean Region ◽  
Wide Spectrum ◽  
New Drugs ◽  
Pharmacological Properties ◽  
Laurus Nobilis ◽  
The Family ◽  
Pharmacological Studies ◽  
Southern Mediterranean ◽  
Leaf Oil ◽  
Different Parts

Laurus nobilis L., commonly known as bay leaves, is native to the southern Mediterranean region. It is a small tree belonging to the genus Laurus of the family Lauraceae. The essential oils created from the different parts of this plant, such as the leaves and flowers, have been used in the food, drug, and cosmetic industries. The essential oil chiefly consists of 1,8-cineole, sabinene, α-pinene, and p-Cymene. Researchers have reported that bay leaves possess various biological and pharmacological properties, such as antibacterial, antifungal, antioxidant, insecticidal, and nematicidal activities. Pharmacological studies found that bay leaf oil could be a promising candidate with the potential for designing new drugs. The goal of this review is to summarize the ethnomedicinal importance, phytochemistry, and wide spectrum of pharmacological and therapeutic applications of bay leaves, which will be useful to researchers for further study.

Pharmacognostical and pharmacological activity of Justicia gendarussa burm.f.: a comprehensive review

2020 ◽  
Vol 11 (3) ◽  
pp. 3384-3390
Author(s):  
Ashish ◽  
Anjali ◽  
Dixit Praveen K ◽  
Nagarajan K ◽  
Sahoo Jagannath
Keyword(s):  
Pharmacological Activity ◽  
Chemical Constituents ◽  
Biological Action ◽  
Andaman Islands ◽  
Comprehensive Review ◽  
Medicinal Value ◽  
Anti Oxidant ◽  
Phytochemical Constituents ◽  
Pharmacologically Active ◽  
Different Parts

Justicia gendarussa Burm .f. (family Acanthaceae) which is also known as willow-leaves and commonly known as Nili-Nirgundi, it is very commonly found nearby to China and its availability is very common in larger parts of India and Andaman islands. Traditionally it is used to treat various sorts of disorders such as wound healing, anti-inflammatory, anti-oxidant, antiproliferative, anti-arthritic etc. Justicia gendarussa is one of the crucial herbs which has been used in the Ayurveda. Majorly leaves parts of the plant shows the pharmacological activity but the root of the plant Justicia gendarussa is also have the important medicinal values. A large variety of pharmacologically active constituents i.e., alkaloids, flavonoids, saponin, carbohydrates, steroids, triterpenoids, carotenoids, aminoacids, tannins, phenolics, coumarines and anthaquinones are also present in this plant and they makes the plant pharmacologically important. The activity of the plant is also dependent on the solvent which is used for the extraction the various vital chemical constituents. The different- different parts of the plants having the different medicinal values also differ in the chemical values. This review is not only focused on the essential phytochemical constituents which is available in the plant but it also explains their necessary medicinal value to shows the essential biological action and phytopharmacological actions of various parts of the plant.

ASSESSMENT OF TOXICITY OF GERMANIUM COORDINATION COMPOUNDS

2019 ◽  
pp. 16-21
Author(s):  
A. V. Kadomtsevа ◽  
I. V. Zhdanovich ◽  
M. S. Piskunovа ◽  
A. N. Lineva ◽  
A. N. Novikova ◽  
...  
Keyword(s):  
Coordination Compounds ◽  
Organometallic Compounds ◽  
Biologically Active ◽  
Pharmacological Properties ◽  
Toxicological Studies ◽  
Methods Of Synthesis ◽  
Promising Area

The synthesis of biologically active coordination compounds and the design on their basis of effective pharmacological preparations is currently the promising area. This paper presents the results of the toxicological studies on digermanium and its complex derivatives. It should be noted that the positive medical properties of organometallic compounds of germanium are confirmed by numerous studies, therefore, the development of the methods of synthesis, as well as investigations of physicochemical and pharmacological properties of these compounds are at the center of attention.

Biologically Active 2,5-Disubstituted-1,3,4-Oxadiazoles

2009 ◽  
Vol 2 (1) ◽  
pp. 390-406
Author(s):  
Harish Rajak ◽  
Murli Dhar Kharya ◽  
Pradeep Mishra
Keyword(s):  
Heterocyclic Compounds ◽  
Medical Literature ◽  
Biological Activities ◽  
Biologically Active ◽  
Pharmacological Properties ◽  
Clinical Use ◽  
Synthetic Drugs ◽  
Physiologic Activity ◽  
Pharmacologically Active

There are vast numbers of pharmacologically active heterocyclic compounds in regular clinical use. The presence of heterocyclic structures in diverse types of compounds is strongly indicative of the profound effects such structure exerts on physiologic activity, and recognition of this is abundantly reflected in efforts to find useful synthetic drugs. The 1,3,4-oxadiazole nucleus has emerged as one of the potential pharmacophore responsible for diverse pharmacological properties. Medical Literature is flooded with reports of a variety of biological activities of 2,5-Disubstituted-1,3,4-oxadiazoles. The present work is an attempt to summarize and enlist the various reports published on biologically active 2,5-disubstituted-1,3,4-oxadiazoles.

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