scholarly journals Encapsulation of Metal and Metal Oxide Nanoparticles by Nutraceuticals: Implications for Biological Activities

2020 ◽  
Vol 01 ◽  
Author(s):  
Muna A. Ali ◽  
Kareem A. Mosa

Background:: The concept of nutraceuticals has gained increased interest recently as it is based on using natural substances for therapeutic applications. However, limitations such as low bioavailability have restricted the use of these substances thus far. Nanoencapsulation of nutraceuticals has been proposed as a promising solution to circumvent such issues by increasing their bioavailability and targeting their release. Metal and metal oxide nanoparticles are amongst the inorganic nanocarriers that have been studied for their ability to encapsulate nutraceuticals. Objectives:: The aim of this article is to provide an overview of metal and metal oxide nanoparticles and their synthesis and applications. Furthermore, the conjugation of these nanoparticles with nutraceuticals will be discussed along with their potential applications. Conclusion:: It has been observed that the conjugation of nutraceuticals with metal nanoparticles resulted in the cumulative properties of both these factors with increased effectiveness. Such advancements are crucial for nutraceutical use in important theranostic applications that combine diagnosis and therapy.

2020 ◽  
Vol 10 (3) ◽  
pp. 185-202
Author(s):  
Anju Arya ◽  
Tejpal Singh Chundawat

In recent time, green synthesis of metal nanoparticles is the latest developing technology and received prodigious interest because it is easy, environmentally pristine, non-fouling, antitoxic, and lowcost approach. Green route of biogenic synthesis of metal nanoparticles via microbes such as bacteria, fungi, virus, yeast and algae has the potential to deliver sustainable and enviro safe protocol. Green synthesized metal nanoparticles are the most optimistic and novel agent for various catalytic and biological activities as antibacterial, antiviral, anticancer etc. without any toxic effects. Here, we reviewed algae-mediated green synthesis of metal and metal oxide nanoparticles and their biological activity. Algae are photoautotrophic, eukaryotic, aquatic, unicellular or multicellular organisms. Algae commonly used for biosynthesis because they grow rapidly, their biomass growth on average ten times faster than higher plants and easy to handle experiments with algal species. Different algal strains such as red, green and brown algae are using for the green synthesis of metal nanoparticles. Algae contain bioactive molecules and secondary metabolites that act as reducing, capping and stabilizing agent for manufacturing in nanoparticles. Biogenically synthesized metal and metal oxide nanoparticles characterized by different techniques such as UV-visible spectroscopy, SEM (scanning electron microscopy), HR-TEM (high-resolution transmission electron microscopy), XRD (X-ray diffraction), TGA (thermogravimetric analysis), DLS (dynamic light scattering) zeta potential and exhibited biological activity. In future, research algal production of metal nanoparticles can be explored by the use of different microalgae and their applications in different areas such as biological activity, catalytic activity in the synthesis of organic compounds, medical diagnose and synthesis of nanocomposite, lipid nanoparticles and antibiofilm.


2020 ◽  
Vol 8 (10) ◽  
pp. 1545 ◽  
Author(s):  
Liubov Shkodenko ◽  
Ilia Kassirov ◽  
Elena Koshel

At present, there is an urgent need in medicine and industry to develop new approaches to eliminate bacterial biofilms. Considering the low efficiency of classical approaches to biofilm eradication and the growing problem of antibiotic resistance, the introduction of nanomaterials may be a promising solution. Outstanding antimicrobial properties have been demonstrated by nanoparticles (NPs) of metal oxides and their nanocomposites. The review presents a comparative analysis of antibiofilm properties of various metal oxide NPs (primarily, CuO, Fe3O4, TiO2, ZnO, MgO, and Al2O3 NPs) and nanocomposites, as well as mechanisms of their effect on plankton bacteria cells and biofilms. The potential mutagenicity of metal oxide NPs and safety problems of their wide application are also discussed.


2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Laura S. Acosta-Torres ◽  
Luz M. López-Marín ◽  
R. Elvira Núñez-Anita ◽  
Genoveva Hernández-Padrón ◽  
Victor M. Castaño

Nowadays, most products for dental restoration are produced from acrylic resins based on heat-cured Poly(Methyl MethAcrylate) (PMMA). The addition of metal nanoparticles to organic materials is known to increase the surface hydrophobicity and to reduce adherence to biomolecules. This paper describes the use of nanostructured materials, TiO2and Fe2O3, for simultaneously coloring and/or improving the antimicrobial properties of PMMA resins. Nanoparticles of metal oxides were included during suspension polymerization to produce hybrid metal oxides-alginate-containing PMMA. Metal oxide nanoparticles were characterized by dynamic light scattering, and X-ray diffraction. Physicochemical characterization of synthesized resins was assessed by a combination of spectroscopy, scanning electron microscopy, viscometry, porosity, and mechanical tests. Adherence ofCandida albicanscells and cellular compatibility assays were performed to explore biocompatibility and microbial adhesion of standard and novel materials. Our results show that introduction of biocompatible metal nanoparticles is a suitable means for the improvement of conventional acrylic dental resins.


2020 ◽  
Vol 28 (3) ◽  
pp. 294-310 ◽  
Author(s):  
Weitao Liu ◽  
Aurang Zeb ◽  
Jiapan Lian ◽  
Jiani Wu ◽  
Hongxia Xiong ◽  
...  

Over the past decade, the production and applications of metal-based and metal-oxide nanoparticles (MBNPs and MONPs, respectively) have increased significantly due to their enhanced physicochemical properties and biological activities when compared with their bulk parent materials. Once MBNPs and MONPs enter agricultural soil via direct or indirect pathways, they can interact with crop plants and thus pose a threat to both animal and human health through food chain pathways. Although many review articles on engineered nanoparticles have been published, few have focused on the interactions of MBNPs and MONPs with crop plants and their current applications. Therefore, we reviewed the sources and behaviors of MBNPs and MONPs in agricultural soil, physiological and biochemical effects of MBNPs and MONPs on plants, uptake, translocation of MBNPs and MONPs in crop plants, factors affecting the interaction between MBNPs and MONPs and plants, and the applications of MBNPs and MONPs. Lastly, we propose where the future research priorities should be focused to provide a better understanding of MBNPs and MONPs. This review will help to promote scientific research regarding MBNPs and MONPs and to understand the risks and benefits of their association with plants and will contribute to the advancement of nanotechnology.


2021 ◽  
Vol 7 (11) ◽  
pp. 145
Author(s):  
Liubov Soltys ◽  
Ostap Olkhovyy ◽  
Tetiana Tatarchuk ◽  
Mu. Naushad

Increased request for metal and metal oxide nanoparticles nanoparticles has led to their large-scale production using high-energy methods with various toxic solvents. This cause environmental contamination, thus eco-friendly “green” synthesis methods has become necessary. An alternative way to synthesize metal nanoparticles includes using bioresources, such as plants and plant products, bacteria, fungi, yeast, algae, etc. “Green” synthesis has low toxicity, is safe for human health and environment compared to other methods, meaning it is the best approach for obtaining metal and metal oxide nanoparticles. This review reveals 12 principles of “green” chemistry and examples of biological components suitable for “green” synthesis, as well as modern scientific research of eco-friendly synthesis methods of magnetic and metal nanoparticles. Particularly, using extracts of green tea, fruits, roots, leaves, etc., to obtain Fe3O4 NPs. The various precursors as egg white (albumen), leaf and fruit extracts, etc., can be used for the „green” synthesis of spinel magnetic NPs. “Green” nanoparticles are being widely used as antimicrobials, photocatalysts and adsorbents. “Green” magnetic nanoparticles demonstrate low toxicity and high biocompatibility, which allows for their biomedical application, especially for targeted drug delivery, contrast imaging and magnetic hyperthermia applications. The synthesis of silver, gold, platinum and palladium nanoparticles using extracts from fungi, red algae, fruits, etc., has been described.


2017 ◽  
Vol 53 (27) ◽  
pp. 3810-3813 ◽  
Author(s):  
Jangkeun Cho ◽  
Leilei Xu ◽  
Changbum Jo ◽  
Ryong Ryoo

A strategy for achieving a high dispersion of metal and metal oxide nanoparticles in a mono-modal fashion is developed.


2021 ◽  
Vol 2 (1) ◽  
pp. 70-81
Author(s):  
Eleen Dayana Mohamed Isa ◽  
Kamyar Shameli ◽  
Nurfatehah Wahyuny Che Jusoh ◽  
Siti Nur Amalina Mohamad Sukri ◽  
Nur’Afini Ismail

Water pollution is one of the major problems faced by mankind worldwide. With the increase of populations and urbanization, the natural water resources are under great threat due to the release of untreated effluent. An alternative treatment method, photocatalysis, emerged as a promising solution. Photocatalysis process utilizes photosensitive catalyst to degrade the pollutant and one of the most common catalyst being used is metal oxide. To increase the photocatalytic activity, nanosized metal oxide being used instead of its bulk form. In these recent years, metal oxide nanoparticles production has been shifted towards a more environmentally friendly process which is also commonly known as green synthesis. In this review, we discussed on the photocatalytic process and production via green synthesis of common metal oxide nanoparticles being used as photocatalyst.


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