scholarly journals Impact of Erodium moschatum (L.) L.'Hér. extracts against some bacteria and fungi species

2018 ◽  
Vol 7 (11) ◽  
pp. 2457
Author(s):  
Mostafa Qahtan Mosataf ◽  
Sirwan Hassan Salih ◽  
Talib Ouaid Alkhazraji
Keyword(s):  
Pathogenic Bacteria ◽  
Pathogenic Fungi ◽  
Trichophyton Mentagrophytes ◽  
Antimicrobial Activities ◽  
Plant Parts ◽  
Streptococcus Lactis ◽  
Entire Plant ◽  
The Difference ◽  
Bacteria And Fungi ◽  
Geographical Locations

The effectiveness of Erodium moschatum extracts (ethanol and methanol, water) were tested against pathogenic bacteria (two gram positive: Staphylococcus aureus and Streptococcus lactis and two gram negative: Escherichia coli and Proteus mirabilis) and four pathogenic fungi (Microsprum canis, Trichophyton mentagrophytes, Pencillium chrysogenum and Fusarium oxysporeum). Tannins, flavonoid and glycoside contents were studied by using HPLC technique and their antimicrobial activities were examined. The results showed the extracts efficacy on the tested microbes in which the ethanol with 11.11mm methanol with 11.22mm diameter were the most effective against the studied bacteria compared with the rest of the studied extracts, either in the fungi it was found that the studied extracts did not have significant differences in their effectiveness against the tested fungi, the results seemed that there are a difference in the concentration of studied active compounds according to the environment (geographical locations) and the difference in the plant parts, rutin showed the highest concentration in the entire plant (Sulaymaniyah) at concentration 22.92ppm compared to the rest of the compounds and Saladin locality and the studied plant part.

scholarly journals Antimicrobial Activities of Marine Sponge-Associated Bacteria

2021 ◽  
Vol 9 (1) ◽  
pp. 171
Author(s):  
Yitayal S. Anteneh ◽  
Qi Yang ◽  
Melissa H. Brown ◽  
Christopher M. M. Franco
Keyword(s):  
Pathogenic Bacteria ◽  
South Australia ◽  
Multidrug Resistant ◽  
Antimicrobial Activities ◽  
Marine Sponges ◽  
Bioactive Metabolites ◽  
Human Pathogens ◽  
Sponge Associated Bacteria ◽  
Microbial Symbionts ◽  
Bacteria And Fungi

The misuse and overuse of antibiotics have led to the emergence of multidrug-resistant microorganisms, which decreases the chance of treating those infected with existing antibiotics. This resistance calls for the search of new antimicrobials from prolific producers of novel natural products including marine sponges. Many of the novel active compounds reported from sponges have originated from their microbial symbionts. Therefore, this study aims to screen for bioactive metabolites from bacteria isolated from sponges. Twelve sponge samples were collected from South Australian marine environments and grown on seven isolation media under four incubation conditions; a total of 1234 bacterial isolates were obtained. Of these, 169 bacteria were tested in media optimized for production of antimicrobial metabolites and screened against eleven human pathogens. Seventy bacteria were found to be active against at least one test bacterial or fungal pathogen, while 37% of the tested bacteria showed activity against Staphylococcus aureus including methicillin-resistant strains and antifungal activity was produced by 21% the isolates. A potential novel active compound was purified possessing inhibitory activity against S. aureus. Using 16S rRNA, the strain was identified as Streptomyces sp. Our study highlights that the marine sponges of South Australia are a rich source of abundant and diverse bacteria producing metabolites with antimicrobial activities against human pathogenic bacteria and fungi.

scholarly journals Size and Shape-Dependent Antimicrobial Activities of Silver and Gold Nanoparticles: A Model Study as Potential Fungicides

Molecules ◽  
2020 ◽  
Vol 25 (11) ◽  
pp. 2682 ◽  
Author(s):  
Francis J. Osonga ◽  
Ali Akgul ◽  
Idris Yazgan ◽  
Ayfer Akgul ◽  
Gaddi B. Eshun ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Pathogenic Fungi ◽  
Antimicrobial Activities ◽  
Plant Diseases ◽  
Production Plant ◽  
Silver And Gold Nanoparticles ◽  
Size And Shape ◽  
Model Study ◽  
Pathogenic Microbes ◽  
Bacteria And Fungi

Plant-based pathogenic microbes hinder the yield and quality of food production. Plant diseases have caused an increase in food costs due to crop destruction. There is a need to develop novel methods that can target and mitigate pathogenic microbes. This study focuses on investigating the effects of luteolin tetraphosphate derived silver nanoparticles (LTP-AgNPs) and gold nanoparticles (LTP-AuNPs) as a therapeutic agent on the growth and expression of plant-based bacteria and fungi. In this study, the silver and gold nanoparticles were synthesized at room temperature using luteolin tetraphosphate (LTP) as the reducing and capping agents. The synthesis of LTP-AgNPs and LTP-AuNP was characterized by Transmission Electron Microscopy (TEM) and size distribution. The TEM images of both LTP-AgNPs and LTP-AuNPs showed different sizes and shapes (spherical, quasi-spherical, and cuboidal). The antimicrobial test was conducted using fungi: Aspergillus nidulans, Trichaptum biforme, Penicillium italicum, Fusarium oxysporum, and Colletotrichum gloeosporioides, while the class of bacteria employed include Pseudomonas aeruginosa, Aeromonas hydrophila, Escherichia coli, and Citrobacter freundii as Gram (−) bacteria, and Listeria monocytogenes and Staphylococcus epidermidis as Gram (+) bacterium. The antifungal study demonstrated the selective size and shape-dependent capabilities in which smaller sized spherical (9 nm) and quasi-spherical (21 nm) AgNPs exhibited 100% inhibition of the tested fungi and bacteria. The LTP-AgNPs exhibited a higher antimicrobial activity than LTP-AuNPs. We have demonstrated that smaller sized AgNPs showed excellent inhibition of A. nidulans growth compared to the larger size nanoparticles. These results suggest that LTP-AuNP and LTP-AgNPs could be used to address the detection and remediation of pathogenic fungi, respectively.

scholarly journals Synthesis, characterization and microbial screening of some new methyl 4, 6-o-(4-methoxybenzylidene)-?-D-glucopyranoside Derivatives

2014 ◽  
Vol 37 (2) ◽  
pp. 145-158 ◽  
Author(s):  
Sarkar MA Kawsar ◽  
Abul K MS Kabir ◽  
Mohammad M R Bhuiyan ◽  
Jannatul Ferdous ◽  
Mohammad S Rahman
Keyword(s):  
Pathogenic Bacteria ◽  
Pathogenic Fungi ◽  
Antimicrobial Activities ◽  
Bacterial Strains ◽  
Additional Information ◽  
Fungal Phytopathogens ◽  
New Compounds ◽  
Academy Of Sciences ◽  
Derivatives Of

Regioselective pentanoylation of methyl 4,6-O-(4-methoxybenzylidene)-?-D-glucopyranoside by the direct acylation method provided the methyl 4,6-O-(4-methoxybenzylidene)-2-O-pentanoyl- ?-D-glucopyranoside in good yield. A number of 3-O-acyl derivatives of this 2-O-pentanoylation product were also prepared in order to obtain new compounds and also gather additional information for structure elucidation. The chemical structure of the newly synthesized compounds was characterized by analytical and spectral methods. Synthesized acylated derivatives of Dglucopyranoside were screened for in vitro antimicrobial activities against ten human pathogenic bacteria and four plant pathogenic fungi. The study revealed that the acylated products exhibited moderate to good antimicrobial activities. It was interesting to observe that the selected compounds were more sensitive against fungal phytopathogens than those of the bacterial strains. DOI: http://dx.doi.org/10.3329/jbas.v37i2.17554 Journal of Bangladesh Academy of Sciences, Vol. 37, No. 2, 145-158, 2013

scholarly journals Isolation and Identification of Saccharomyces cerevisiae from Caterpillar Frass and their Probiotic Characterization

2019 ◽  
Vol 16 (1) ◽  
pp. 179-186 ◽  
Author(s):  
Ujwala Vinayak Khisti ◽  
Suyash Arun Kathade ◽  
Mayur Arjun Aswani ◽  
Pashmin Kaur Anand ◽  
Nirichan Kunchirman Bipinraj
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Pathogenic Bacteria ◽  
Antimicrobial Activities ◽  
Yeast Cells ◽  
Isolation And Identification ◽  
Yeast Cultures ◽  
Isolation And Characterization ◽  
Wide Range ◽  
Probiotic Yeast ◽  
Bacteria And Fungi

Probiotics are live microorganisms which upon ingestion confer health benefits to the host and are widely applied for human and animal welfare. The present study reports the isolation of yeast cells from caterpillar frasses and its probiotic characterization. Out of four yeast cultures isolated, all found to be non-hemolytic and cultures designated as CV-I, CV-II CV-III and CV-IV showed good bile tolerance at 1.2%. These cultures possessed the ability to grow pH range of 1.5 – 10, exhibited auto-aggregation and co-aggregation capabilities, which are essential for growth in alimentary canal and reduction of pathogen adherence on the intestinal epithelial cells. All cultures exhibited good tolerance to temperature up to 42°C. Isolate CV-I showed wide range of antimicrobial activities against pathogenic bacteria and fungi. This study is the first report of isolation and characterization of probiotic yeast from caterpillar frass. The isolate CV-I has been identified as Saccharomyces cerevisiae by molecular methods. This culture is an ideal candidate for further probiotic exploration.

scholarly journals Bioactivity of pyocyanin of Pseudomonas aeruginosa clinical isolates against a variety of human pathogenic bacteria and fungi species

10.3823/812 ◽  
2017 ◽  
Vol 7 (3) ◽  
Author(s):  
Zahraa Jaafar Jameel ◽  
Anaam Fuad Hussain ◽  
Muthana Abdulkhader Al-Mahdawi ◽  
Nuha F. Abed Alkerim ◽  
Eman Sabah Abd Alrahman
Keyword(s):  
Antimicrobial Activity ◽  
Secondary Metabolites ◽  
Pathogenic Bacteria ◽  
Pathogenic Fungi ◽  
Blue Pigment ◽  
Candida Spp ◽  
Source Of Infection ◽  
Redox Active ◽  
Bacteria And Fungi ◽  
Human Infections

Pyocyanin is blue pigment redox active, secondary metabolites produced by P. aeruginosa. The present study investigated the bioactivity of pyocyanin against certain types of bacteria and fungi causing human infections Objectives: Pyocyanin is blue pigment redox active, secondary metabolites produced by P. aeruginosa. The current study deals with biosynthesis, purification and bioactivity of pyocyanin produced by P. aeruginosa. Design: Pyocyanin extraction was done by chloroform method and concentration was determined by multiplying the optical density at 520 nm by 17.072 expressed as µg/ml. Biological activity of pyocyanin was determined by well diffusion procedure. Results: According to the source of infection, results showed that P. aeruginosa were most common in ear infection (30%) followed by wounds (22%), burns (17%), urine (13%) and each in stool and diabetes (9%). In this study the high resistance of  P. aeruginosa  isolates to antibiotics were 19 (82.6 %) to piperacillin followed by 10(43.5%) to aztreonem, 8(34.8%) to meropenem, 6(26.1%) to amikacin, 5(21.7%) to ciprofloxacin then 2(8.7%) to cefotaxime. the urine isolate produced the largest amount of pyocyanin (15.894 µg/ml). pyaocyanin have antimicrobial activity against Pathogenic bacteria: Shigella,  Staphyllococcus aureus and  Staphyllococcus epidermedis. and pathogenic fungi and yeast: Aspergillus niger, Penicillium spp., Rhizopus spp, Trichophyton  mentagrophyte, Rhodotorula spp., Alternaria alternate , Trichophyton rubrum and Candida spp Conclusions: cefotaxime is the best antibiotic for P. aeruginosa. Antimicrobial activity of pyocyanin against gram positive more than gram negative bacteria but less than that observed against fungi (molds and yeast).

In-Vitro Cytotoxicity, Antimicrobial activities and DNA binding studies, of Novel Copper (II) complex with Heterocyclic base

2021 ◽  
pp. 3051-3055
Author(s):  
Shalini V. ◽  
Deepika R. ◽  
Arumugham M. N
Keyword(s):  
Dna Binding ◽  
Pathogenic Bacteria ◽  
Spectroscopic Method ◽  
Antimicrobial Activities ◽  
In Vitro Cytotoxicity ◽  
Binding Studies ◽  
Heterocyclic Base ◽  
Heterocyclic Ligand ◽  
Bacteria And Fungi

A novel ternary copper (II) complex have been synthesized by the addition of N, N-heterocyclic ligand with L-amino acid. The copper (II) complex, [Cu(1,10-phen) (L-Thr) Br] (where phen=1,10-phenanthroline and Threo=Threonine) characterized by various spectroscopic method. The intense UV band around 271nm was due to π-π* transition. The DNA binding study of these copper (II) complex are examined by UV–Visible, Emission spectroscopic, cyclic voltammetric and viscosity method. The results revealed that complex shown to be a intercalation mode of binding into DNA. The anticancer activity of Cu (II) complexes has capability to the kill HepG2 liver cancer cell as assessed by the MTT method, The Ic50value was found 21.50µg/ml The biological activity of the complex tested against certain pathogenic bacteria and fungi results revealed it was found to be potent antibacterial agent.

scholarly journals Antimicrobial activities of chicken β-defensin (4 and 10) peptides against pathogenic bacteria and fungi

2015 ◽  
Vol 5 ◽  
Author(s):  
Haitham A. Yacoub ◽  
Ahmed M. Elazzazy ◽  
Osama A. H. Abuzinadah ◽  
Ahmed M. Al-Hejin ◽  
Maged M. Mahmoud ◽  
...  
Keyword(s):  
Pathogenic Bacteria ◽  
Antimicrobial Activities ◽  
Bacteria And Fungi
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