Anti-Cancer Effect of UV Irradiation at Presence of Cadmium Oxide (CdO) Nanoparticles on DNA of Cancer Cells: A Photodynamic Therapy Study

In this work, the effect of temperature of the ablation environment on the properties of Cadmium Oxide (CdO) nanoparticles produced by synchrotron radiation is investigated. To produce nanoparticles, synchrotron radiation pulse with 1064 (nm) wavelength is used to emit Cadmium in the human cancer cells, tissues and tumors. All test parameters were kept constant and human cancer cells, tissues and tumors temperature was changed to produce samples at 20°C and 65°C. Then, ATR–FTIR, XRD, TEM and UV–Visible spectroscopy analyses were performed to investigate their properties. The results show that the size of nanoparticles is increased by increase in temperature of ablation environment. In addition, in the current experimental research, Gold (Au)–Cadmium Oxide (CdO) alloy is created at the size of nano. In this regard, same volume of Gold and Cadmium Oxide (CdO) solutions were mixed together and emitted by the synchrotron radiation pulse with wavelength of 532 (nm). The Gold and Cadmium Oxide (CdO) solutions have been produced, separately, using synchrotron radiation ablation process. To produce them, synchrotron radiation pulse with wavelength of 1064 (nm) and pulse width of 7 (ns) and repeating frequency of 5 (Hz) was used. The results show that synchrotron radiation emission with wavelength of 532 (nm) is an appropriate method for producing Gold compounds in the size of nano.

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Enhancing the Raman Scattering for Diagnosis and Treatment of Human Cancer Cells, Tissues and Tumors using Cadmium Oxide (Cdo) Nanoparticles

Journal of Toxicology and Risk Assessment ◽

10.23937/2572-4061.1510012 ◽

2018 ◽

Vol 4 (1) ◽

Cited By ~ 1

Author(s):

Heidari Alireza

Keyword(s):

Raman Scattering ◽

Cancer Cells ◽

Human Cancer ◽

Cadmium Oxide ◽

Diagnosis And Treatment ◽

Human Cancer Cells ◽

Cdo Nanoparticles

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Photodynamic Therapy and Hyperthermia in Combination Treatment—Neglected Forces in the Fight against Cancer

Pharmaceutics ◽

10.3390/pharmaceutics13081147 ◽

2021 ◽

Vol 13 (8) ◽

pp. 1147

Author(s):

Aleksandra Bienia ◽

Olga Wiecheć-Cudak ◽

Aleksandra Anna Murzyn ◽

Martyna Krzykawska-Serda

Keyword(s):

Photodynamic Therapy ◽

Combination Therapy ◽

Cancer Treatment ◽

Cancer Cells ◽

Combination Treatment ◽

Therapeutic Agent ◽

Diagnostic Methods ◽

Cancer Therapies ◽

Treatment Side Effects ◽

Anti Cancer

Cancer is one of the leading causes of death in humans. Despite the progress in cancer treatment, and an increase in the effectiveness of diagnostic methods, cancer is still highly lethal and very difficult to treat in many cases. Combination therapy, in the context of cancer treatment, seems to be a promising option that may allow minimizing treatment side effects and may have a significant impact on the cure. It may also increase the effectiveness of anti-cancer therapies. Moreover, combination treatment can significantly increase delivery of drugs to cancerous tissues. Photodynamic therapy and hyperthermia seem to be ideal examples that prove the effectiveness of combination therapy. These two kinds of therapy can kill cancer cells through different mechanisms and activate various signaling pathways. Both PDT and hyperthermia play significant roles in the perfusion of a tumor and the network of blood vessels wrapped around it. The main goal of combination therapy is to combine separate mechanisms of action that will make cancer cells more sensitive to a given therapeutic agent. Such an approach in treatment may contribute toward increasing its effectiveness, optimizing the cancer treatment process in the future.

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