scholarly journals EVALUASI PENGGUNAAN ANTIBIOTIK PADA PASIEN PASCABEDAH APENDISITIS AKUT DI RSUD KABUPATEN PASURUAN TAHUN 2018 (Penelitian dilakukan di Instalasi Rawat Inap RSUD Kabupaten Pasuruan)

2020 ◽  
Vol 6 (1) ◽  
pp. 15-20
Author(s):  
Wirda Anggraini ◽  
◽  
Novia Beta Wiraningtias ◽  
Fidia Rizkiah Inayatilah ◽  
Yen Yen Ari Indrawijaya ◽  
...  
Keyword(s):  
Acute Appendicitis ◽  
Anatomical Therapeutic Chemical ◽  
Vermiform Appendix ◽  
Antibiotic Use ◽  
Defined Daily Dose ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Parenteral Route ◽  
Antibiotics Use

Acute appendicitis is an infection that occurs in vermiform appendix, and because of that it needs to do appendectomy immediately. Appendectomy is included in clean contaminated operation category which allows Surgical Site Infection (SSI). The antibiotics use in post-surgical patients to prevent the infections. The aims of this study to identify profile and determine the quantity and quality of antibiotics use. This study used cross sectional study with retrospective data on patient’s medical records after surgery for acute appendicitis in General Hospital Pasuruan Regency on January-December 2018. Data analysis was performed descriptively. The result of this study showed that the highest profile of the antibiotic use for mono therapy was Cefuroxime (25.81%) and for combination therapy were Phosphomycin + Metronidazole (8.06%) and Ceftriaxone + Metronidazole (8.06%). The quantity of antibiotics use by using Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) method was obtained total DDD value 52.01 DDD/100 patient-days with the highest antibiotic was Metronidazole parenteral route 14.00 DDD/100 patient-days. Antibiotics included in Drug Utilization 90% (DU 90%) segment were (Metronidazole, Ceftriaxone, Phosphomycin, Cefuroxime, Gentamicin) by parenteral route. The quality of antibiotics use based on the Infectious Disease Society of America (IDSA) Guidelines, appropriate indication (11.86%), appropriate dose (52,54%), appropriate interval (22,03%), appropriate route (96.61%) and appropriate duration of treatment (28.81%).

scholarly journals Antibiotic use on paediatric inpatients in a public hospital in Bangil, Indonesia

2021 ◽  
pp. 163-167
Author(s):  
Ika Norcahyanti ◽  
Malikatur Rosyidah ◽  
Abdul Kadir Jaelani ◽  
Antonius N.W. Pratama
Keyword(s):  
Public Hospital ◽  
Anatomical Therapeutic Chemical ◽  
Action Plan ◽  
Antibiotic Use ◽  
Defined Daily Dose ◽  
Cross Sectional ◽  
Pediatric Ward ◽  
Global Action ◽  
Bed Days ◽  
Cross Sectional Design

Introduction: The importance of antibiotic use in a clinical setting was evaluated in order to support the global action plan to decelerate the spreading speed of antimicrobial resistance. Objective: This study aimed to evaluate antibiotic use among pediatric inpatients in Bangil public hospital, East Java, Indonesia. Methods: This study used a cross-sectional design. The data were obtained from medical records of pediatric patients admitted to a pediatric ward in 2017. Data were analysed using the anatomical therapeutic chemical classification system (ATC)/defined daily dose (DDD) method in conjunction with data sources from a locally developed bacterial map. Results: The results showed the paediatric patients were dominantly male (n=218; 54.2%) and mostly diagnosed with diarrhoea (n=87; 15.3%). Ampicillin-sulbactam was the most commonly used antibiotic (16.3%). The total DDD value was 66.1 DDD/100 bed-days, and ceftriaxone demonstrated the highest DDD value (10.3 DDD/100 bed-days). Conclusion: In conclusion, the use of antibiotics in the pediatric ward in Bangil public hospital was comparable to other studies conducted in Indonesia.

scholarly journals Effects of Clinical Pathway Implementation in Management of Pediatric Inpatients with Pneumonia: A Cross-Sectional Study in Indonesia

2020 ◽  
Vol 11 (4) ◽  
pp. 7281-7288
Author(s):  
Assajada Lizikri ◽  
Wawaimuli Arozal ◽  
Hesty Utami Ramadaniati
Keyword(s):  
Clinical Outcomes ◽  
Clinical Pathway ◽  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Defined Daily Dose ◽  
Cross Sectional ◽  
Before And After ◽  
Discernible Difference ◽  
Third Generation Cephalosporins

Pneumonia is the leading cause of morbidity and mortality in children worldwide. Antibiotics are the mainstay treatment for bacterial pneumonia so their use should be clearly mentioned in the pneumonia clinical pathway (CP). This study aimed to evaluate the effectiveness of pneumonia CP in pediatrics. A cross-sectional observational study was conducted in a private hospital in Indonesia. The inclusion criteria were pediatric patients admitted with pneumonia in the period of January-December 2017 (pre-CP period) and January-December 2018 (post-CP) and receiving antibiotics. The effectiveness of CP was evaluated according to four parameters: length of stay, clinical outcomes, quality (Gyssens antibiogram) and quantity of antibiotics. A total of 121 eligible patients’ medical records were analyzed (60 before and 61 after CP implementation). Second and third generation cephalosporins (42.1%) predominated the use of antibiotics pre-CP period, whilst aminoglycosides (59.6%) constituted more than half of antibiotic use in post-CP group. More than half of the patients stayed in the hospital not more than 3 days pre-CP period vs 31.1% post-CP period. Nearly all patients had good clinical outcomes during hospitalization between both periods. The proportion of quality of antibiotics was less than 5% either before or after CP implementation. The quantity of antibiotics post-CP (408.42 defined daily dose/DDD per 100 patient days) was almost two times of pre-CP period (222.42 DDD per 100 patient days). In conclusion, implementation of CP could not achieve the targeted goals to reduce the length of hospitalization and improve the antibiotic use. No discernible difference was observed in clinical outcomes before and after CP implementation.

scholarly journals Antibiotic use on paediatric inpatients in a public hospital in Bangil, Indonesia

2021 ◽  
pp. 163-167
Author(s):  
Ika Norcahyanti ◽  
Malikatur Rosyidah ◽  
Abdul Kadir Jaelani ◽  
Antonius N.W Pratama
Keyword(s):  
Public Hospital ◽  
Anatomical Therapeutic Chemical ◽  
Action Plan ◽  
Antibiotic Use ◽  
Defined Daily Dose ◽  
Cross Sectional ◽  
Pediatric Ward ◽  
Global Action ◽  
Bed Days ◽  
Cross Sectional Design

Introduction: The importance of antibiotic use in a clinical setting was evaluated in order to support the global action plan to decelerate the spreading speed of antimicrobial resistance. Aim: This study aimed to evaluate antibiotic use among pediatric inpatients in Bangil public hospital, East Java, Indonesia. Methods: This study used a cross-sectional design. The data were obtained from medical records of pediatric patients admitted to a pediatric ward in 2017. Data were analysed using the anatomical therapeutic chemical classification system (ATC)/defined daily dose (DDD) method in conjunction with data sources from a locally developed bacterial map. Results: The results showed the paediatric patients were dominantly male (n=218; 54.2%) and mostly diagnosed with diarrhoea (n=87; 15.3%). Ampicillin-sulbactam was the most commonly used antibiotic (16.3%). The total DDD value was 66.1 DDD/100 bed-days, and ceftriaxone demonstrated the highest DDD value (10.3 DDD/100 bed-days). Conclusion: In conclusion, the use of antibiotics in the pediatric ward in Bangil public hospital was comparable to other studies conducted in Indonesia.

Appendicoliths: the neglected stones

2017 ◽  
Vol 4 (1) ◽  
pp. 3-6
Author(s):  
Saroj Dhital ◽  
Udaya Koirala ◽  
Birendra Dhoj Joshi ◽  
Amit Mani Upadhyaya ◽  
Arbin Joshi
Keyword(s):  
Acute Appendicitis ◽  
Iliac Fossa ◽  
Vermiform Appendix ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Recurrent Appendicitis ◽  
Right Iliac Fossa Pain

Introductions: Cases of colic of the vermiform appendix have been rarely described or diagnosed. Appendicoliths cause acute appendicitis and appendicular perforation. It is still not clear whether appendicoliths cause appendicular colic in the absence of acute appendicitis. Methods: A cross sectional study that included appendectomy done for recurrent appendicitis or chronic right iliac fossa pain. Histology reports were reviewed. The presence of an appendicolith in the report was noted. Results: Thirty-two cases of recurrent appendicitis and chronic right iliac fossa pain were included. Twenty-four patients (75%) had fecoliths in the histology specimens. Eight patients (25%) who presented with appendicular colic without signs of appendicitis were further evaluated. Conclusions: Majority of patients with chronic or colicky right iliac fossa pain had appendicoliths.

scholarly journals IMPACT OF ANTIMICROBIAL STEWARDSHIP PROGRAM ON THE USE OF ANTIBIOTICS IN PNEUMONIA PATIENTS AT TEACHING HOSPITAL IN SURAKARTA INDONESIA

2021 ◽  
pp. 20-23
Author(s):  
HIDAYAH KARUNIAWATI ◽  
TRI YULIANTI ◽  
DEWI KUROTA AINI ◽  
FINISHIA ISNA NURWIENDA
Keyword(s):  
Antimicrobial Stewardship ◽  
Antibiotic Use ◽  
Study Data ◽  
Defined Daily Dose ◽  
Inappropriate Use ◽  
Stewardship Program ◽  
Daily Dose ◽  
The Impact ◽  
Method Show

Objective: Antibiotic resistance is a serious problem worldwide. One cause of antibacterial resistance is the inappropriate use of antibiotics. Thestudy of antibiotic use in hospitals found that 30–80% were not based on indications. Antimicrobial Stewardship Programs (ASP) was developed tocontrol antimicrobial resistance. This study aims to evaluate the impact of ASP in pneumonia patients qualitatively and quantitatively pre-post ASPapplied.Methods: This research is a non-experimental study. Data were taken from the medical records of pneumonia patients and analyzed qualitativelyusing the Gyssens method and quantitatively using the Defined Daily Dose (DDD) method. Sampling was conducted through purposive sampling andresults were described descriptively.Results: During the study period, 96 samples were obtained with 48 data pre-ASP and 48 data post-ASP. The results of the qualitative analysis usingthe Gyssens method show an increase in the prudent use of antibiotics from 31.25% to 62.5% pre-post ASP, respectively. Quantitative evaluationshows a decrease of antibiotic use pre-post ASP from 90.84 DDD/100 patients-days to 61.42 DDD/100 patients-days.Conclusion: The ASP can improve the quality of antibiotic use in pneumonia patients quantitatively and qualitatively.

scholarly journals Evaluasi Penggunaan Antibiotik Pada Pasien Anak Rawat Inap di RSD Dr. Soebandi Jember

2020 ◽  
Author(s):  
Sinta Rachmawati ◽  
Dewi Khurmi Masito ◽  
Ema Rachmawati
Keyword(s):  
Antibiotic Resistance ◽  
Quantitative Evaluation ◽  
Pediatric Patients ◽  
Anatomical Therapeutic Chemical ◽  
Antibiotic Use ◽  
Defined Daily Dose ◽  
Resistance Risk ◽  
Condition Evaluation ◽  
Daily Dose ◽  
Active Substances

Infection is one of the health problems. It is mostly caused by bacteria. The increased incidence of bacterial infection results in higher antibiotic use. It can lead to antibiotic resistance risk. Antibiotic resistance may occur in pediatric patients. Morbidity, mortality, and high cost of medication are impact of this condition. Evaluation of antibiotic use needs to be done to ensure responsible use of antibiotics. ATCD/DDD (Anatomical Therapeutic Chemical/ Defined Daily Dose) method can be used to evaluate antibiotic use quantitatively. ATC classification is a system of grouping active substances according to their location of action and DDD is a measurement system that is connected to the ATC code.The purpose of this study was determining the profile of antibiotic use and measuring quantitative evaluation with ATC/DDD method in pediatric patients. The data was collected by observing the hospital medical record. The results of this study showed that cephalosporin (46,22%) was the most used group and cefotaxime (31,15%) was the most used type of antibiotic. While, the quantitative evaluation with ATC/DDD method indicated that the highest of antibiotic use was ceftriaxone (11,30 DDD/100 patient days) and the lowest was amikacin (0,03 DDD/100 patient days)

scholarly journals Pharmaco-Economic Aspects of Antibiotic Prescriptions in Clinics of Kathmandu

2004 ◽  
Vol 43 (152) ◽  
pp. 83-87
Author(s):  
Akhilesh Chandra Jauhari ◽  
A Pokharel ◽  
N Palikharel ◽  
N Shrestha ◽  
BS Rao
Keyword(s):  
Financial Burden ◽  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Human Immune Deficiency Virus ◽  
Prescribing Pattern ◽  
Cross Sectional ◽  
Sexually Transmitted ◽  
Proper Diagnosis ◽  
Human Immune

Antibiotics (AB) are the most widely prescribed group of drugs and their use is associated with increasingrate of AB resistance. Nearly one third of prescriptions of physicians for colds, upper respiratory tractinfections and bronchitis are of AB as documented in previous studies. Antibiotic use is associated withincreased cost of financial burden, which may be difficult to be borne by the patients in developing countrieslike Nepal.The objective was study the prescribing pattern of Antibiotic preparations in various diseases and to findout how the treatment could become more pharmaco-economic without compromising the quality of service.A cross sectional study of prescription pattern of antibiotics/drugs in which antibiotics were used fromrandomly selected 20 private clinics of four major specialties in Kathmandu valley.Total No. of prescriptions audited were 386, average number of drugs/per prescription was 2.74.Maximum antibiotics were prescribed for age group 21-40 years in gynecological, surgical and medicalproblems, in Pediatrics maximum AB were prescribed between 1-12 years.Minimum antibiotics were prescribed between 13-20 years for gynecological and Pediatric problems. Inmedical and surgical problems, minimums AB were administered between 41-60 years. Above 60 yearsalmost no AB were used.Males were prescribed more AB than females (73% for surgical, 62% for medical and 53% for Pediatricproblems)Only in 20.25% patients, AB were prescribed after proper diagnosis and sensitivity testsMaximum cost of prescription was 510 Nepali rupees (NR) for treatment of STD in Gynecology.Key Words: Antibiotics, Cost, Human Immune deficiency Virus, Kathmandu, Private Clinics, Pharmacoeconomic, Sexually Transmitted Diseases.

scholarly journals EVALUASI KUALITATIF PENGGUNAAN ANTIBIOTIK PADA PASIEN PNEUMONIA RS “X’’ DI MALANG

2021 ◽  
Vol 3 (1) ◽  
pp. 9-21
Author(s):  
Wirda Anggraini
Keyword(s):  
Antibiotic Resistance ◽  
Antibiotic Therapy ◽  
Medical Record ◽  
Antibiotic Use ◽  
Observational Method ◽  
Negative Effects ◽  
Cross Sectional ◽  
Cross Sectional Design

Abstract—Pneumonia was an inflammation that occurs in the lungs accompanied by exudation and consolidation of microorganisms. In Indonesia, the prevalence of pneumonia continues to increase. Treatment of pneumonia uses antibiotic therapy. The use of antibiotics needs to be controlled by evaluating the quality of antibiotic use to prevent negative effects that can occur on patients, such as antibiotic resistance. The purpose of this study was to determine the quality of antibiotic use in pneumonia patients. This study did with observational method with cross-sectional design. The study was conducted in August-September 2019. Qualitative evaluations did with Gyssen method. The results of 35 medical record samples that fulfill the criteria showed that 21.43% of cases category 0; 16.67% of cases category I; 0% of cases category II C; 33.34% of cases in category II B; 4.76% of cases category II A; 0% of cases category III B; 0% of cases category III A; 0% of cases category IV D; 19.05% of cases category IV C; 4.76% of cases category IV B; 61.90% of cases category IV A; 0% of cases category V; 0% of cases category VI. Thus, rational cases (category I) were 21,43% and irrational cases (categories I-IV) were 78,57%.

scholarly journals Inappropriate Use of Antibiotics and Their Predictors in Pediatric Patients Admitted at the Hospital Central De Nampula, Mozambique

2021 ◽  
Author(s):  
Sancho Pedro Xavier ◽  
Audêncio Victor ◽  
Graciano Cumaquela ◽  
Melsequisete Daniel Vasco ◽  
Osiyallê Rodrigues ◽  
...  
Keyword(s):  
Logistic Regression ◽  
Pediatric Patients ◽  
Treatment Time ◽  
Binary Logistic Regression ◽  
Antibiotic Use ◽  
P Value ◽  
Binary Logistic Regression Analysis ◽  
Duration Of Treatment ◽  
Cross Sectional ◽  
Inappropriate Use

Abstract Background Antibiotics are synthetic or natural substances used to treat diseases of infectious origin. When used incorrectly, they can be a factor in the development of antimicrobial resistance, increased treatment time, costs, and mortality. The present study aimed to assess the pattern inappropriate use of antibiotics and their predictors in pediatric patients admitted to the Hospital Central de Nampula, Mozambique Methods A cross-sectional, retrospective study with a quantitative approach was conducted between January and July 2019. The population consisted of children aged 0 to 10 years hospitalized in the pediatric ward I. Binary logistic regression was used to determine risk factors for inappropriate use of antibiotics with 95% CI. Results The prevalence of antibiotic use among pediatric patients was 97.5%. Of the 464 antibiotics prescribed, 39.9% were for patients suffering from gastroenteritis, 21.8% and 9.1% Affected with pneumonia and malaria. Most antibiotics were for systemic use (95.9%, 445/464). Most (36.5%) of prescriptions had errors. Duration of treatment (74.6%) and dosage (25.4%) were the most frequent errors. Binary logistic regression analysis revealed that patients were prescribed with ≥ 3 antibiotics (OR = 2.920, 95% CI = 1.283–6.646, p–value = 0.011) and with a short hospitalization time (OR = 1.726, 95% CI = 1.040–2.864, p–value = 0.035) were more likely to experience some inappropriate use of antibiotics. Conclusion The study showed a higher prevalence of antibiotic use, however, a greater number of prescriptions contained errors. Errors related to dose and duration of treatment were the most common among pediatric patients. These results reveal a concern, since inappropriate and excessive use of antibiotics is a major factor for the development of antibiotic resistant microorganisms. Therefore, strategies concerning the use of antibiotics in order to reduce their inappropriate and excessive use are necessary.

scholarly journals Antibiotic use in Moshi Urban: A cross-sectional Study of Knowledge and Practices among Caretakers of Children in Kilimanjaro Tanzania

2021 ◽  
Vol 4 (3) ◽  
pp. 347-356
Author(s):  
Benedicto J Petro ◽  
Sixbert Isdory Mkumbaye ◽  
Rukia Rajab Bakar ◽  
Nassra Is-hak Yussuf ◽  
Pius G. Horumpende ◽  
...  
Keyword(s):  
Antibiotic Use ◽  
Cross Sectional Study ◽  
Good Knowledge ◽  
Sectional Study ◽  
Self Medication ◽  
Cross Sectional ◽  
Media Campaigns ◽  
Antibiotics Use ◽  
Sick Children ◽  
Rational Use Of Antibiotics

IntroductionAntibiotics are commonly accessed and used for the management of illness in children without a prescription. We investigated the caretaker’s knowledge and practices on antibiotics and antibiotics use to their children.MethodThis was the hospital-based cross-sectional study conducted from April to July 2017 in three facilities located in Moshi Municipality. A convenience sampling was employed to select for caretakers with their sick children at KCMC, Mawenzi hospital, and Longuo dispensary. Face-to-face interviews were conducted with 224 caretakers who had visited health facilities with their children seeking health care.ResultsThe majority (87.9%, 197/224) of all interviewed caretakers had good knowledge of the use of antibiotics. Irrespective of knowing that it is not safe to self-medicate a child with any antibiotics (95.1%, 213/224), most (61.6%, 138/224) caretakers practiced self-medication with the medicines. Having two children (aOR = 7.75, 95% CI: 1.89-31.67) and having three children (aOR=7.23, 95%CI: 1.08-48.51) were significantly associated with good knowledge of antibiotics.ConclusionThis study has revealed that caretakers in Moshi had a good knowledge of antibiotic use. However, despite such good knowledge, malpractices were observed. We call upon the use of media campaigns to advocate for the importance of the rational use of antibiotics and its effect on human health and the risk of antimicrobial resistance development.Rwanda J Med Health Sci 2021;4(3):347-356

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