scholarly journals Assess the Knowledge Regarding Effect and Side Effect of Folic Acid and Ferrous Sulphate Among Anemic Women

2021 ◽  
Vol 14 (9) ◽  
pp. 379-382
Author(s):  
Achita Sawarkar
Keyword(s):  
Folic Acid ◽  
Side Effect ◽  
Ferrous Sulphate

Iron and folic acid in pregnancy: ferrograd folic

1968 ◽  
Vol 6 (3) ◽  
pp. 12.1-12
Keyword(s):  
Folic Acid ◽  
Iron Deficiency ◽  
Slow Release ◽  
Ferrous Sulphate ◽  
Elemental Iron ◽  
Ferrous Fumarate ◽  
Iron And Folic Acid ◽  
In Pregnancy

Abbott Laboratories have drawn our attention to their Ferrograd Folic tablets which were introduced shortly after we discussed combined iron and folic acid tablets (DTB March 17, 1967, p. 22.). Like A. H. Cox’s ferrous fumarate and folic acid tablet (DTB November 24, 1967, p. 96), Ferrograd Folic provides what we concluded were appropriate amounts of folic acid and iron for prophylaxis of folate and iron deficiency in pregnancy. Each tablet contains 350 mcg folic acid and 105 mg elemental iron as slowly released ferrous sulphate; the dose is one tablet daily. The basic NHS cost of one week’s supply is 1/9d, much more than that of Cox’s tablets, but slow release of the iron is probably an advantage for some patients.

scholarly journals EVALUATION THERMOANALYTICAL OF WHEAT FLOUR FORTIFIED WITH FOLIC ACID AND FERROUS SULPHATE

2009 ◽  
Vol 06 (12) ◽  
pp. 47-50
Author(s):  
Eliane Gonçalves ARAÚJO ◽  
Nedja Suely FERNANDES
Keyword(s):  
Thermal Stability ◽  
Differential Scanning Calorimetry ◽  
Folic Acid ◽  
Wheat Flour ◽  
Ferrous Sulphate ◽  
Scanning Calorimetry ◽  
Iron Sulphate ◽  
Derivative Thermogravimetry

In this work wheat flour aditived with folic acid and iron sulphate was evaluated by Thermogravimetry (TG), Derivative Thermogravimetry (DTG) and differential scanning calorimetry (DSC) for evaluation of the thermal stability. The results obtained showed that the samples of wheat flour have similar behaviour.

Can Iron and Folic Acid-IFA and Ca & Vitamin D Supplementation in Pregnancy be Fitted into Habitual Pattern of Three Meals A Day?

2019 ◽  
Vol 56 (4) ◽  
pp. 341
Author(s):  
Prema Ramachandran ◽  
Amrita Pramanik ◽  
K. Kalaivani
Keyword(s):  
Vitamin D ◽  
Folic Acid ◽  
Side Effects ◽  
Pregnant Women ◽  
Ferrous Sulphate ◽  
Vitamin D Supplementation ◽  
Meal Pattern ◽  
Iron And Folic Acid ◽  
Habitual Pattern ◽  
In Pregnancy

In India prevalence of anaemia and vitamin D deficiency in pregnancy are widespread. National programmes recommend that two tablets of iron and folic acid (IFA) and two tablets of calcium and vitamin D (Ca & Vit D) to be given every day from second trimester till delivery. To minimize the side effects and increase compliance, it is advised that each tablet should be taken after a meal. Most households follow a three meal pattern. A study was taken up to find out how IFA and Ca & Vit D supplementations can be fitted into the habitual three meal pattern. A short term crossover supplementation study was carried out on 38 pregnant women to assess side effects following consumption after lunch of one or two tablets containing 500mg elemental calcium (as calcium carbonate) and 250 IU vitamin D or 60 mg of elemental iron as ferrous sulphate. Prevalence of side effects was higher in women who received iron supplements as compared to Ca & Vit D supplements. Taking two tablets of Ca & Vit D together after meal was associated with significantly higher prevalence of side effects as compared to taking one tablet after meal. Taking two tablets of iron together after meal was not associated with any significant increase in prevalence of side effects as compared to one tablet. Giving two tablets of iron together after one meal and giving one tablet of calcium and vitamin after two meals is feasible option for providing two tablets each of iron and Ca & Vit D to pregnant women who habitually follow a three meal pattern.

Studies in iron supplementation of preschool children

1978 ◽  
Vol 39 (3) ◽  
pp. 493-499 ◽  
Author(s):  
Sheila M. Pereira ◽  
Almas Begum ◽  
S. J. Baker
Keyword(s):  
Folic Acid ◽  
Preschool Children ◽  
Iron Supplementation ◽  
Binding Capacity ◽  
Ferrous Sulphate ◽  
Percentage Saturation ◽  
Growth Activity

1. The effect of daily supplements of 20–30 mg inorganic iron as ferrous sulphate on the growth, activity and haematological status of preschool children was studied for 3.5, 7 and 12 months and compared to that of children who served as controls. All children were given their daily requirements of energy and protein. In addition, they received 5 μg cyanocobalamin and 200 μg folic acid.2. Fe supplementation increased the haemoglobin, serum Fe and percentage saturation of transferrin and reduced the unsaturated Fe-binding capacity significantly compared to corresponding values for the controls.3. Height and activity were unaffected by Fe supplements.4. Of the children 45% had haemoglobin values below 110 g/l at the end of 7–12 months of Fe supplementation.

scholarly journals The effect of folic acid and iron in the prevention of nutritional anaemias in pregnancy in Nigeria

1970 ◽  
Vol 24 (3) ◽  
pp. 689-694 ◽  
Author(s):  
'Bola O.A. Osifo
Keyword(s):  
Folic Acid ◽  
Pregnant Women ◽  
Seasonal Changes ◽  
Ferrous Sulphate ◽  
Dietary Intakes ◽  
Folic Acid Intake ◽  
Blood Samples ◽  
Folic Acid Supplements ◽  
Group A ◽  
Group B

1. Fifty-two pregnant women in a village were divided into three groups, A, B and C, and were given the following supplements: A, iron in the form of 200 mg ferrous sulphate daily; B, Fe(as group A) and 5 mg of folic acid daily; C, Fe and folic acid (as group B) plus an antimalarial drug.2. Blood samples were collected each week and assessed for haemoglobin and haematocrit values.3. Dietary intakes of Fe and folic acid were calculated for both pregnant and non-pregnant women. Results revealed that Fe intake was adequate and Fe deficiency not common. The supplement of Fe increased the haemoglobin levels.4. Folic acid intake was low and intake probably fluctuated during the year because of seasonal changes in the dietary folic acid.5. About 28% of patients, during their first attendance, had haematocrit values below normal. Folic acid supplements increased these values.

scholarly journals The Influence of Antenatal Oral Iron and Folic Acid Side Effects on Supplementation Duration in Low-Resource Rural Kenya: A Cross-Sectional Study

2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Shadrack Oiye ◽  
Margaret Juma ◽  
Silvenus Konyole ◽  
Fatuma Adan
Keyword(s):  
Folic Acid ◽  
Side Effects ◽  
Side Effect ◽  
Safe Motherhood ◽  
Folate Intake ◽  
Cross Sectional ◽  
Low Resource ◽  
Stomach Pain ◽  
Rural Kenya ◽  
Iron And Folic Acid

Background. Undesirable effects of a daily regimen of iron and folic acid ingested jointly (iron-folate) are potential disincentives to optimal antenatal supplementation. We intended to profile antenatal iron-folate side effects and elucidate their influence on supplementation duration in low-resource rural Kenya. Methods. This was a cross-sectional descriptive study of randomly selected postnatal mothers of under-five-year-old children. Using a modified WHO Safe Motherhood Assessment standard questionnaire, they recalled the total number of days of antenatal iron-folate intake and the attendant supplement-attributed undesirable experiences. The analyses considered only participants who ingested the supplements in their immediate last pregnancies (n=277). Results. About half of the study participants reported at least a side effect and a mean of 2.4 (SD 1.5) effects per person in the entire pregnancy period. Most common reported effects were chest pains (31.8%), constipation (28.5%), severe stomach pains (11.6%), and diarrhoea (11.6%). Mothers who reported at least a side effect ingested the supplements for ten days less compared to those who did not experience any effect (p=0.03); and a greater proportion of the former were primigravida (p=0.02) and used combined form of iron and folic acid (p=0.003). In a multivariate analysis, significant correlations with supplementation compliance (ingestion for 90+ days) were found only for nausea and severe stomach pain experiences (r=−0.1, p=0.04; r=0.2, p=0.01, resp.). Conclusions. The commonness of undesirable experiences attributed to daily ingestion of 60 mg iron and 0.4 mg folic acid and their deterrence to longer supplementation durations suggest the need for considering a weekly intermittent regimen for some antenatal women in such set-ups. Our study demonstrated that potentially, more counselling on nausea as a side effect might be critical in advancing iron-folate supplementation compliance.

Plexafer-F in the Management of Latent Iron Deficiency in Pregnancy

1978 ◽  
Vol 6 (1) ◽  
pp. 34-40 ◽  
Author(s):  
A M Afifi
Keyword(s):  
Folic Acid ◽  
Iron Deficiency ◽  
Ferrous Sulphate ◽  
Drug Intake ◽  
Iron Supply ◽  
Child Bearing ◽  
High Incidence ◽  
Latent Iron Deficiency ◽  
Stool Specimens ◽  
In Pregnancy

The failure to prescribe in antenatal clinics a well tolerated form of supplementary oral iron that provides an adequate iron supply for the successful maintainance of active erythropoiesis in pregnant women largely accounts for the frequent development of latent iron deficiency in the child-bearing age. The potential value of Plexafer-F*, a slow release ferrous sulphate preparation supplemented with folic acid, in reducing the high incidence of latent iron deficiency in pregnancy was assessed by conducting a randomized clinical trial of Plexafer-F and ordinary ferrous sulphate B.P. with folic acid in eighty women presenting early in pregnancy with latent iron deficiency. At the end of the trial, which was started at the sixteenth week of pregnancy and which lasted for twenty weeks, normal haematological values were obtained in thirty-eight out of forty patients (95%) taking Plexafer-F, but only in twenty-four out of forty patients (60%) taking ferrous sulphate. A simple screening test run on stool specimens provided during antenatal visits to check regular ingestion of the iron preparations prescribed, revealed regular drug intake and no intolerance in all the patients receiving Plexafer-F, against an intolerance leading to failure of regular drug intake in 37.5% of patients receiving ordinary ferrous sulphate.

The Morphology of the Rat Kidney Following Folic Acid Administration

1970 ◽  
Vol 28 ◽  
pp. 200-201
Author(s):  
Aline Byrnes ◽  
Elsa E. Ramos ◽  
Minoru Suzuki ◽  
E.D. Mayfield
Keyword(s):  
Folic Acid ◽  
De Novo ◽  
Specific Activity ◽  
Rat Kidney ◽  
Present Report ◽  
Intracellular Localization ◽  
Male Rats ◽  
Renal Hypertrophy ◽  
Electron Microscopic ◽  
Biochemical Alterations

Renal hypertrophy was induced in 100 g male rats by the injection of 250 mg folic acid (FA) dissolved in 0.3 M NaHCO3/kg body weight (i.v.). Preliminary studies of the biochemical alterations in ribonucleic acid (RNA) metabolism of the renal tissue have been reported recently (1). They are: RNA content and concentration, orotic acid-c14 incorporation into RNA and acid soluble nucleotide pool, intracellular localization of the newly synthesized RNA, and the specific activity of enzymes of the de novo pyrimidine biosynthesis pathway. The present report describes the light and electron microscopic observations in these animals. For light microscopy, kidney slices were fixed in formalin, embedded, sectioned, and stained with H & E and PAS.

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