At a glance on Coronavirus Disease (COVID-19): Pathogenesis, Innate and acquired mechanisms, Host-virus genomes interactions, Therapeutic options and prevention (Preprint)

2020 ◽  
Author(s):  
Desh Deepak Singh
Keyword(s):  
Prevention And Control ◽  
Infection Prevention ◽  
Specific Problem ◽  
Control Measure ◽  
Review Article ◽  
Therapeutic Options ◽  
Infection Prevention And Control ◽  
Public Health Threat ◽  
Virus Genomes ◽  
And Control

UNSTRUCTURED On 11th march 2020 WHO declared COVID-19 is pandemic. The ongoing outbreak is global and as on 22 May 2020, 5.2 Million Cases, 337000 deaths of COVID-19 were recorded by more than 200 counties. COVID -19 is public health threat and rapidly transmitting diseases the globally. The sign and symptoms of COVID-19 infection in primary stage are non-specific, a number of more cases are observed than initially expected. There is urgent requirement for improved knowledge in diagnosis, pathophysiology, preventive and therapeutic options. Published reviews on the COIVD-19 are based on the specific problem and very few review articles are available on recent development of 2019-nCoV2 infection to minimize any barriers which effect the prevention and transmission against COVID-19 outbreak. The aim of this review article is to explore recent updates on COVID -19 infection in context of pathogenesis during disease progression, Innate and acquired mechanisms of defence against, Advances in the diagnostics , Susceptibility and severity of Host-virus genomes interactions, Modes and dynamics of transmission, Active compounds in the context of pre-clinical and clinical for the treatment ,Vaccine developments and Effectiveness of COVID-19 infection prevention and control measure.

scholarly journals The First Family Cluster of COVID-19 in Bangladesh- Enigma in Developing Country

2020 ◽  
pp. 141-144
Author(s):  
Md Robed Amin ◽  
Mohiuddin Sharif ◽  
MA Faiz
Keyword(s):  
Health Care ◽  
Health System ◽  
Prevention And Control ◽  
Infection Prevention ◽  
Control Measure ◽  
Infection Prevention And Control ◽  
South East Asia ◽  
Testing Approach ◽  
And Control ◽  
Multiple Strategy

Currently 221 countries of the globe is affected with COVID- 19 pandemic caused by a novel corona virus naming SARSCoV- 2 and leads to more than 4000000 confirmed cases and more than 300000 death already. The South East Asia regions have many LMIC status where the health system is disorganized and less prepared than what it should be. Although India and Pakistan started to react against the pandemic with multiple strategy to combat the bloom of the epidemic, Bangladesh was relaxing as there were lack of confirmation of cases and although the country has prolonged period of time to combat the pandemic situation, it was not proactive from the beginning. Inappropriate screening at entry, poor quarantine process and gross lack of infection prevention and control measure leads to observe the confirmed cases to develop one by one. Even in this conservative testing approach of Bangladesh, a family of cluster (6 members) of confirmed COVID 19 was observed with development of huge question in health care system. J Bangladesh Coll Phys Surg 2020; 38(0): 141-144

Effective infection prevention and control strategies in a large accredited psychiatric facility in Singapore

2020 ◽  
Author(s):  
Daniel Poremski ◽  
Sandra Henrietta Subner ◽  
Grace Lam Fong Kin ◽  
Raveen Dev Ram Dev ◽  
Mok Yee Ming ◽  
...  
Keyword(s):  
Mental Health ◽  
Prevention And Control ◽  
Infection Prevention ◽  
Control Strategies ◽  
Infection Prevention And Control ◽  
Psychiatric Facility ◽  
Essential Services ◽  
Community Transmission ◽  
And Control

The Institute of Mental Health in Singapore continues to attempt to prevent the introduction of COVID-19, despite community transmission. Essential services are maintained and quarantine measures are currently unnecessary. To help similar organizations, strategies are listed along three themes: sustaining essential services, preventing infection, and managing human and consumable resources.

Barriers to infection prevention and control practice among Amhara region teaching hospitals in Ethiopia: Qualitative study

2019 ◽  
Vol 15 (2) ◽  
Author(s):  
Walelegn Worku Yallew ◽  
Abera Kumie ◽  
Feleke Moges Yehuala
Keyword(s):  
Healthcare Worker ◽  
Prevention And Control ◽  
Healthcare Workers ◽  
Infection Prevention ◽  
Teaching Hospitals ◽  
Infection Prevention And Control ◽  
Amhara Region ◽  
Implementation Barriers ◽  
Control Practice ◽  
And Control

Healthcare workers have good perception towards infection prevention, but there has been a poor practice towards it. Therefore, the aim of this study was to explore barriers to practice of infection prevention and control practice in teaching hospitals in Amhara region. A phenomenological approach used to explore the lived experience of healthcare workers and management staffs towards infection prevention practice and control. The data was collected from ten in-depth interviews and 23 focus group discussion participants, by face to face interview using open ended interview performed in safe and quiet places. Data was managed using OpenCode software version 4.03 and contents were analyzed thematically. Totally ten different barriers were identified, such as availability of facilities, shortage of material supply, lack of maintenance of facilities and equipment, high patient flow, experience, emergency situation, healthcare worker behaviour and healthcare worker’s information about infection prevention, low awareness of patients and visitors and overflow of families and visitors to the hospital. For effective infection prevention practice implementation, barriers should be considered via identifying specific organizational, healthcare worker, patients and visitors as targets.

scholarly journals Infection control practices and challenges in Pakistan during the COVID-19 pandemic: a multicentre cross-sectional study

2021 ◽  
pp. 175717742110127
Author(s):  
Salma Abbas ◽  
Faisal Sultan
Keyword(s):  
Personal Protective Equipment ◽  
Prevention And Control ◽  
Infection Prevention ◽  
Hospital Staff ◽  
Cross Sectional Study ◽  
Infection Prevention And Control ◽  
Protective Equipment ◽  
Cross Sectional ◽  
Healthcare Facilities ◽  
And Control

Background: Patient and staff safety at healthcare facilities during outbreaks hinges on a prompt infection prevention and control response. Physicians leading these programmes have encountered numerous obstacles during the pandemic. Aim/objective: The aim of this study was to evaluate infection prevention and control practices and explore the challenges in Pakistan during the coronavirus disease 2019 pandemic. Methods: We conducted a cross-sectional study and administered a survey to physicians leading infection prevention and control programmes at 18 hospitals in Pakistan. Results: All participants implemented universal masking, limited the intake of patients and designated separate triage areas, wards and intensive care units for coronavirus disease 2019 patients at their hospitals. Eleven (61%) physicians reported personal protective equipment shortages. Staff at three (17%) hospitals worked without the appropriate personal protective equipment due to limited supplies. All participants felt overworked and 17 (94%) reported stress. Physicians identified the lack of negative pressure rooms, fear and anxiety among hospital staff, rapidly evolving guidelines, personal protective equipment shortages and opposition from hospital staff regarding the choice of recommended personal protective equipment as major challenges during the pandemic. Discussion: The results of this study highlight the challenges faced by physicians leading infection prevention and control programmes in Pakistan. It is essential to support infection prevention and control personnel and bridge the identified gaps to ensure patient and staff safety at healthcare facilities.

scholarly journals Challenges to Infection Control Team during COVID-19 Pandemic in a Quaternary Medical Center in Saudi Arabia

2021 ◽  
pp. 1-20
Author(s):  
Hala A Amer ◽  
Ibrahim A Alowidah ◽  
Chasteffi Bugtai ◽  
Barbara M. Soule ◽  
Ziad A Memish
Keyword(s):  
Saudi Arabia ◽  
Infection Control ◽  
Prevention And Control ◽  
Infection Prevention ◽  
Task Force ◽  
Care Center ◽  
Capital City ◽  
Infection Prevention And Control ◽  
Team Approach ◽  
And Control

Abstract Background: King Saud Medical City (KSMC) is a quaternary care center based in the center of the capital city, Riyadh, Kingdom of Saudi Arabia (KSA) and is one of the key Ministry of Health (MoH) facilities dedicated to the care of COVID-19 patients in the central region. Methods: A comprehensive surge plan was promptly launched in mid-March 2020 to address the pandemic and then expanded in a phase-wise approach. Supporting the capacity of the infection prevention and control department (IPCD) was one of the main pillars of KSMC surge plan. Task force Infection Control teams have been formulated to tackle the different aspects of pandemic containment processes. The challenges and measures undertaken by the IPC team have been described. Conclusion: Realizing the more prominent role of infection prevention and control staff as frontline responders to public health emergencies like COVID-19, a solid infection prevention and control system at the healthcare setting supported by qualified and sufficient manpower, a well-developed multidisciplinary team approach, electronic infrastructure and efficient supply utilization is required for effective crisis management.

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