“Correlation of Salivary Cortisol Levels with Anxiety in Type II Diabetes Mellitus Patients before and after Complete Denture Rehabilitation.” (Preprint)

2021 ◽  
Author(s):  
Dr Akansha Vilas Bansod ◽  
Dr Sweta Kale Pisulkar
Keyword(s):  
Salivary Cortisol ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Complete Denture ◽  
Type Ii ◽  
Before And After ◽  
Anxiety Levels ◽  
Cortisol Levels ◽  
Edentulous Patients ◽  
The Relationship

BACKGROUND Complete edentulism constitutes global health care burden. People with no teeth fail to eat and speak effectively. This results in emotional alterations and a reduction in quality of life of the patients, raising their stress levels. Stressful situations cause increased blood pressure and heart rate resulting in the secretion of cortisol hormone, which is a cardinal regulator of physiologic stress response. Cortisol stimulates gluconeogenesis and glycogenolysis causing hyperglycemia, which may favor the occurrence of Diabetes and other glucose metabolism disorders. As the diabetics population is rapidly rising throughout the world and with growing life expectancy, Prosthodontists are certain to see more number of diabetic edentulous patients. Thus, there is a need to assess the relationship of complete denture rehabilitation with the generic health of edentulous patients which can be done by checking the stress levels, with the help of hormonal markers and their effects on systemic health. OBJECTIVE To determine anxiety levels and Salivary Cortisol levels in Type II Diabetes Mellitus Patients and compare and correlate them before and after rehabilitation with Complete Dentures. METHODS It will be a cross-sectional study, carried out on edentulous diabetic patients visiting the OPD of Department of Prosthodontics of Sharad Pawar Dental College and Hospital. With consent of the patients for participation, Glycated Hemoglobin will be measured and anxiety levels will be determined using a DASS-21 Questionnaire along with fabrication of a new set of complete dentures. Patients will be assessed at two stages; before and 1 month after complete denture rehabilitation. The data obtained will be analysed using student paired t-test. RESULTS Significant reduction in anxiety levels after Complete Denture Rehabilitation and thus, a definitive correlation between anxiety and salivary cortisol levels. CONCLUSIONS Patient’s adaptation to new dentures can be improved by the professional’s by gaining knowledge of the relationship between dental rehabilitation and the overall health of edentulous patients.

"Correlation of Salivary Cortisol Levels with Anxiety in Type II Diabetes Mellitus Patients before and after Complete Denture Rehabilitation: An Invivo Study" (Preprint)

2021 ◽  
Author(s):  
Dr Akansha Bansod ◽  
Dr Sweta Kale Pisulkar
Keyword(s):  
Salivary Cortisol ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Complete Denture ◽  
Type Ii ◽  
Before And After ◽  
Anxiety Levels ◽  
Cortisol Levels ◽  
Edentulous Patients ◽  
The Relationship

BACKGROUND Complete edentulism constitutes health care burden, resulting in emotional alterations and a reduction in quality of life of the patients, raising their stress levels. Stressful situations cause increased blood pressure and heart rate resulting in the secretion of cortisol hormone, which stimulates gluconeogenesis and glycogenolysis causing hyperglycemia, which may favor the occurrence of Diabetes. As the diabetics population is rapidly rising, Prosthodontists are certain to see more number of diabetic edentulous patients. Thus, there is a need to assess the relationship of complete denture rehabilitation with the generic health of edentulous patients which can be done by checking the stress levels, and their effects on systemic health. OBJECTIVE To determine anxiety levels and Salivary Cortisol levels in Type II Diabetes Mellitus patients and compare and correlate them before and after rehabilitation with Complete Dentures METHODS It will be a cross-sectional study, carried out on edentulous diabetic patients visiting the Department of Prosthodontics of Sharad Pawar Dental College and Hospital. With consent for participation, Glycated Hemoglobin and anxiety levels will be determined, along with fabrication of complete dentures. Patients will be assessed at two stages; before and 1 month after complete denture rehabilitation RESULTS The research has been approved by the Institutional Ethical Committee.The results expected are the significant reduction in anxiety levels after Complete Denture Rehabilitation and thus, a definitive correlation between anxiety and salivary cortisol levels. CONCLUSIONS Patient’s adaptation to new dentures can be improved by the professional’s by gaining knowledge of the relationship between dental rehabilitation and the overall health of edentulous patients.

Comparison of Behavior and Dental Anxiety During Intranasal and Sublingual Midazolam Sedation – A Randomized Controlled Trial

2016 ◽  
Vol 40 (1) ◽  
pp. 81-87 ◽  
Author(s):  
AK Shanmugaavel ◽  
Sharath Asokan ◽  
John J Baby ◽  
Geetha Priya ◽  
J Gnana Devi
Keyword(s):  
Drug Administration ◽  
Salivary Cortisol ◽  
Anxiety Level ◽  
Anxiety Scale ◽  
Sublingual Administration ◽  
Before And After ◽  
Group A ◽  
Anxiety Levels ◽  
Cortisol Levels ◽  
Group B

Objectives: The objective of the study was to assess the behavioral effects and the changes in the anxiety level of children after intranasal and sublingual midazolam sedation using Venham's clinical anxiety scale and salivary cortisol level. Study Design: Twenty children aged 3 to 7 years were randomly assigned to Group A (n=10) intranasal or Group B (n=10) sublingual midazolam (0.2mg/kg) sedation. The anxiety levels at various time periods were assessed using Venham clinical anxiety scale and corresponding changes in salivary cortisol levels were assessed before and after the drug administration. The anxiety levels were assessed independently by two pediatric dentists from recorded videos. Wilcoxon signed rank test and Mann Whitney U test were used for statistical analysis using SPSS version 19.0.Results: There was a significant decrease in anxiety level from baseline to 20 minutes after drug administration in group A (p=0.004) and group B (p=0.003). There was no significant change in salivary cortisol levels before and after the drug administration in group A (p=0.07) and group B (p=0.38). Conclusions: Both intranasal and sublingual administration of midazolam was equally effective in reducing the child's anxiety. However, there was no significant difference in the salivary cortisol levels in both groups.

Is pseudocholinesterase activity related to markers of triacylglycerol synthesis in Type II diabetes mellitus?

2001 ◽  
Vol 101 (1) ◽  
pp. 29-35 ◽  
Author(s):  
C. RUSTEMEIJER ◽  
J. A. SCHOUTEN ◽  
H. J. VOERMAN ◽  
A. C. BEYNEN ◽  
A. J. M. DONKER ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Cardiovascular Disease ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Stepwise Multiple Regression ◽  
Type Ii ◽  
Stepwise Multiple Regression Analysis ◽  
Triacylglycerol Synthesis ◽  
The Relationship ◽  
Apoe Phenotype

Hypertriglyceridaemia is a risk factor for cardiovascular disease in patients suffering from Type II diabetes mellitus, and is due to enhanced synthesis and/or impaired clearance of triacylglycerol-rich lipoproteins. In the present study we investigated whether pseudocholinesterase (PChE) activity could serve as a marker for the rate of triacylglycerol synthesis in these patients. Patients were stratified according to their apolipoprotein E (apoE) phenotype, i.e. E3E2, E3E3 or E3E4. In study I, the relationship between PChE activity and serum triacylglycerols was investigated in 224 insulin-treated patients with Type II diabetes. In study II, which had a cross-over design, PChE activity was measured in 45 dyslipidaemic, insulin-treated patients with Type II diabetes that were treated with bezafibrate or pravastatin. In study I, PChE activity was correlated positively with serum triacylglycerol concentrations, but did not differ significantly between apoE phenotypes. The strongest relationship was found in the E3E4 group (r = 0.50; P = 0.001), the phenotype for which hypertriglyceridaemia is expected to be the result of increased triacylglycerol synthesis. In a stepwise multiple regression analysis, serum triacylglycerol concentrations were found to be the strongest predictor of PChE activity in the E3E4 group. In study II, PChE activity decreased as a result of bezafibrate treatment in all three apoE groups. The decrease in PChE activity with bezafibrate treatment paralleled the decrease in serum triacylglycerol concentrations in the apoE subgroups. Pravastatin treatment did not significantly affect PChE activity. Thus the present study suggests an association between PChE activity and the rate of triacylglycerol synthesis. Measurement of PChE activity may therefore be a useful tool in the choice of drug for treatment of hypertriglyceridaemia in patients with Type II diabetes.

Role of combined effect of Samsamani Vati and Darvyadi Kwatha in the management of Madhumeha w.s.r. to Type - II Diabetes Mellitus - A Case Study

2018 ◽  
Vol 3 (01) ◽  
Author(s):  
Archana Kashid Zende
Keyword(s):  
Diabetes Mellitus ◽  
Type Ii Diabetes ◽  
Type Ii Diabetes Mellitus ◽  
Combined Effect ◽  
Treatment Result ◽  
Type Ii ◽  
Carbohydrate Utilization ◽  
Presenting Symptoms ◽  
Before And After ◽  
Relative Deficiency

Background: Diabetes Mellitus is a metabolic disorder in which carbohydrate utilization is reduced and that of lipid and protein enhanced; it is caused by an absolute or relative deficiency of insulin and is characterized by Hyperglycemia. The mortality rate due to Diabetes mellitus is very high and is ranked fifth amongst the ten major causes of death in southern part of India. The prevalence of Diabetes in adults globally was estimated to be 150 million and this figure is expected to double by 2025. Ayurveda has described that a rational treatment is one where the medicine modifies the disease; on the other hand it doesn’t provoke new complaints. Due to all these things it has become a challenge for Ayurvedists to search for an additional safe and effective treatment. Objective: To evaluate the combined effect of Samsamanivati and Darvyadi Kwatha in the management of Madhumeha w.s.r. to type -II Diabetes Mellitus. Method: A 55yr old female patient presenting symptoms of Prabhutmutrarta, Naktamutrata, Trushna, Hastapadadaha, Alasya since two years. Patient was k/c/o DM since 2yrs. Patient was treated with Samsamanivati - 250mg (2 tab) two times a day after meal and Darvyadi Kwatha - 40ml. after meals two times a day for three months.BSL(F) and BSL (PP) was done before and after treatment. Result: The combination of these medicines has also shown highly significant in subjective parameters and moderately significant in objective parameters. Conclusion: Theses selected combination of medicines were found to be highly significant in treating type II Daibetes mellitus.

scholarly journals The Relationship of Family Support and Stress with the Quality of Life of the Elderly Type II Diabetes Mellitus

2020 ◽  
Vol 12 (4) ◽  
pp. 1001-1010
Author(s):  
Roza Erda ◽  
Cindy Monica Harefa ◽  
Revi Yulia ◽  
Didi Yunaspi
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Health Center ◽  
Family Support ◽  
Type Ii Diabetes ◽  
The Elderly ◽  
Type Ii Diabetes Mellitus ◽  
Type Ii ◽  
The Relationship

Diabetes is a serious chronic disease that occurs because the pancreas does not produce enough insulin. Quality of life is very important to get serious attention, because the quality of life is something that is closely related to a person's health condition, the severity of the disease, the duration of healing, and can even aggravate the condition of the disease to death if a person has a poor quality of life. This study aims to determine the relationship between family support and stress with the quality of life of the elderly with type II diabetes mellitus in the Sekupang Health Center, Batam City, 2020. Data collection usedthe questionnaire brought by the researcher to the population elderly people with Type II Diabetes Mellitusin Batam City in 2020. The inclusion criteria are elderly who are willing to be respondents, elderly who suffer from Diabetes Mellitus Type II, elderly who are ≥60 years old, elderly who can communicate well, and elderly who do not experience cognitive impairment. Research respondents involved in this study were 64 respondents. Chi-Square statistical test results obtained value (p value = 0.000 <0.05), indicating that H0 is rejected and Ha is accepted. Conclusion: there is a significant relationship between family support and stress with the quality of life of the elderly with type II diabetes mellitus in the Sekupang Health Center, Batam City, 2020.

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