"Correlation of Salivary Cortisol Levels with Anxiety in Type II Diabetes Mellitus Patients before and after Complete Denture Rehabilitation: An Invivo Study" (Preprint)
BACKGROUND Complete edentulism constitutes health care burden, resulting in emotional alterations and a reduction in quality of life of the patients, raising their stress levels. Stressful situations cause increased blood pressure and heart rate resulting in the secretion of cortisol hormone, which stimulates gluconeogenesis and glycogenolysis causing hyperglycemia, which may favor the occurrence of Diabetes. As the diabetics population is rapidly rising, Prosthodontists are certain to see more number of diabetic edentulous patients. Thus, there is a need to assess the relationship of complete denture rehabilitation with the generic health of edentulous patients which can be done by checking the stress levels, and their effects on systemic health. OBJECTIVE To determine anxiety levels and Salivary Cortisol levels in Type II Diabetes Mellitus patients and compare and correlate them before and after rehabilitation with Complete Dentures METHODS It will be a cross-sectional study, carried out on edentulous diabetic patients visiting the Department of Prosthodontics of Sharad Pawar Dental College and Hospital. With consent for participation, Glycated Hemoglobin and anxiety levels will be determined, along with fabrication of complete dentures. Patients will be assessed at two stages; before and 1 month after complete denture rehabilitation RESULTS The research has been approved by the Institutional Ethical Committee.The results expected are the significant reduction in anxiety levels after Complete Denture Rehabilitation and thus, a definitive correlation between anxiety and salivary cortisol levels. CONCLUSIONS Patient’s adaptation to new dentures can be improved by the professional’s by gaining knowledge of the relationship between dental rehabilitation and the overall health of edentulous patients.