scholarly journals Smartphone-Assisted High-Intensity Interval Training in Inflammatory Rheumatic Disease Patients: Randomized Controlled Trial (Preprint)

2021 ◽  
Author(s):  
Håvard Haglo ◽  
Eivind Wang ◽  
Ole Kristian Berg ◽  
Jan Hoff ◽  
Jan Helgerud

BACKGROUND Patients with inflammatory rheumatic diseases (IRDs) experience disease-related barriers to physical training. Compared with the general population, IRD patients are reported to have reduced maximal oxygen uptake (VO<sub>2max</sub>) and physical activity levels. Supervised high-intensity interval training (HIIT) is documented to counteract the reduced VO<sub>2max</sub> and poor cardiovascular health associated with IRDs. However, supervised HIIT is resource demanding. OBJECTIVE This study sought to investigate if self-administered 4×4-min HIIT guided by a smartphone app (Myworkout GO) could yield similar HIIT-induced effects as standard 4×4-min HIIT performed under the guidance and supervision of health care professionals. The effects studied were on VO<sub>2max</sub> and health-related quality of life (HRQoL). METHODS Forty patients (33 female patients, mean age 48 years, SD 12 years; 7 male patients, mean age 52 years, SD 11 years) diagnosed with rheumatoid arthritis, spondyloarthritis, or systemic lupus erythematosus were randomized to a supervised group (SG) or an app group (AG). Both groups were instructed to perform 4×4-min intervals with a rate of perceived exertion of 16 to 17, corresponding to 85% to 95% of the maximal heart rate, twice a week for 10 weeks. Treadmill VO<sub>2max</sub> and HRQoL measured using RAND-36 were assessed before and after the exercise period. RESULTS VO<sub>2max</sub> increased (<i>P</i>&lt;.001) in both groups after 10 weeks of HIIT, with improvements of 3.6 (SD 1.3) mL/kg/min in the SG and 3.7 (SD 1.5) mL/kg/min in the AG. This was accompanied by increases in oxygen pulse in both groups (<i>P</i>&lt;.001), with no between-group differences apparent for either measure. Improvements in the HRQoL dimensions of bodily pain, vitality, and social functioning were observed for both groups (<i>P</i>&lt;.001 to <i>P</i>=.04). Again, no between-group differences were detected. CONCLUSIONS High-intensity 4×4-min interval training increased VO<sub>2max</sub> and HRQoL, contributing to patients’ reduced cardiovascular disease risk, improved health and performance, and enhanced quality of life. Similar improvements were observed following HIIT when IRD patients were guided using perceived exertion by health care professionals or the training was self-administered and guided by the app Myworkout GO. Utilization of the app may help reduce the cost of HIIT as a treatment strategy in this patient population. CLINICALTRIAL ClinicalTrials.gov NCT04649528; https://clinicaltrials.gov/ct2/show/NCT04649528

10.2196/28124 ◽  
2021 ◽  
Vol 9 (10) ◽  
pp. e28124
Author(s):  
Håvard Haglo ◽  
Eivind Wang ◽  
Ole Kristian Berg ◽  
Jan Hoff ◽  
Jan Helgerud

Background Patients with inflammatory rheumatic diseases (IRDs) experience disease-related barriers to physical training. Compared with the general population, IRD patients are reported to have reduced maximal oxygen uptake (VO2max) and physical activity levels. Supervised high-intensity interval training (HIIT) is documented to counteract the reduced VO2max and poor cardiovascular health associated with IRDs. However, supervised HIIT is resource demanding. Objective This study sought to investigate if self-administered 4×4-min HIIT guided by a smartphone app (Myworkout GO) could yield similar HIIT-induced effects as standard 4×4-min HIIT performed under the guidance and supervision of health care professionals. The effects studied were on VO2max and health-related quality of life (HRQoL). Methods Forty patients (33 female patients, mean age 48 years, SD 12 years; 7 male patients, mean age 52 years, SD 11 years) diagnosed with rheumatoid arthritis, spondyloarthritis, or systemic lupus erythematosus were randomized to a supervised group (SG) or an app group (AG). Both groups were instructed to perform 4×4-min intervals with a rate of perceived exertion of 16 to 17, corresponding to 85% to 95% of the maximal heart rate, twice a week for 10 weeks. Treadmill VO2max and HRQoL measured using RAND-36 were assessed before and after the exercise period. Results VO2max increased (P<.001) in both groups after 10 weeks of HIIT, with improvements of 3.6 (SD 1.3) mL/kg/min in the SG and 3.7 (SD 1.5) mL/kg/min in the AG. This was accompanied by increases in oxygen pulse in both groups (P<.001), with no between-group differences apparent for either measure. Improvements in the HRQoL dimensions of bodily pain, vitality, and social functioning were observed for both groups (P<.001 to P=.04). Again, no between-group differences were detected. Conclusions High-intensity 4×4-min interval training increased VO2max and HRQoL, contributing to patients’ reduced cardiovascular disease risk, improved health and performance, and enhanced quality of life. Similar improvements were observed following HIIT when IRD patients were guided using perceived exertion by health care professionals or the training was self-administered and guided by the app Myworkout GO. Utilization of the app may help reduce the cost of HIIT as a treatment strategy in this patient population. Trial Registration ClinicalTrials.gov NCT04649528; https://clinicaltrials.gov/ct2/show/NCT04649528


Author(s):  
Sean Pymer ◽  
Said Ibeggazene ◽  
Joanne Palmer ◽  
George E. Smith ◽  
Amy E. Harwood ◽  
...  

AbstractBackgroundUptake and completion rates for supervised exercise programmes (SEP) for patients with intermittent claudication (IC) are low. Current exercise prescription is a one size fits all approach, based on claudication pain thresholds, potentially limiting individual benefits. High-intensity interval training (HIIT) has the potential to overcome these barriers as it is a more time-efficient, objectively prescribed exercise programme. This study aimed to assess a novel HIIT programme for patients with IC in terms of safety, feasibility, tolerability and indicators of efficacy.Design/MethodsPatients referred to a usual-care SEP were invited to undertake an alternative HIIT programme. All recruited patients performed a baseline cardiopulmonary exercise test (CPET), to inform their exercise prescription. HIIT involved ten, one-minute high-intensity intervals on a stationary cycle ergometer interspersed with one-minute recovery intervals, performed three times per week for six-weeks. Outcomes included safety, feasibility, tolerability, walking distance and quality of life (QoL).Results144 patients with IC were referred, 95 met initial eligibility criteria (66%) and 30 (32%) were recruited for HIIT, of which 15 (50%) completed. Of the recruited patients, 90% were on optimal medical therapy and 40% had concomitant cardiac, cerebrovascular and/or respiratory disease.One serious adverse event was recorded and patients who completed the programme attended 100% of the sessions. Improvements in walking distances and quality of life were observed. Following recruitment of the first 20 patients, the inclusion criteria was refined on the basis of CPET, leading to improved completion rates.ConclusionThe study provides preliminary findings indicating that patients with IC can complete a short-term HIIT programme. HIIT also appears safe, well-tolerated and although not formally powered, walking distances and QoL appear to improve following HIIT. Further research to evaluate the role of HIIT in patients with IC seems warranted.


2015 ◽  
Vol 40 (12) ◽  
pp. 1321-1323 ◽  
Author(s):  
Jennifer L. Reed ◽  
Pablo B. Nery ◽  
David H. Birnie ◽  
Heather E. Tulloch ◽  
Andrew L. Pipe

Persons with permanent atrial fibrillation experience reduced exercise tolerance, weight gain, and an associated decline in overall health. We report on a 74-year-old man with permanent atrial fibrillation who underwent a 10-week high-intensity interval training program. Substantial improvements in heart rate, blood pressure, aerobic and functional capacity, and quality of life were observed. These are desirable as these patients are not candidates for other treatment options and more effective therapies for the treatment of atrial fibrillation are needed.


2018 ◽  
Vol 118 (10) ◽  
pp. 1313-1321 ◽  
Author(s):  
Scott C Adams ◽  
Darren S DeLorey ◽  
Margie H Davenport ◽  
Adrian S Fairey ◽  
Scott North ◽  
...  

2018 ◽  
Vol 38 (4) ◽  
pp. 226-233
Author(s):  
Raymond Pranata ◽  
Emir Yonas ◽  
Bambang B. Siswanto ◽  
Budhi S. Purwowiyoto

Heart failure is one of the most common cardiovascular diseases and is a final pathway of various cardiac pathologies. Exercise intolerance and dyspnea accompanied by dete­riorating quality of life are common issues in those suffering from heart failure and may persist despite optimal medical therapy. Exercise training in heart failure theoretically helps to slow down the deterioration of the heart by antagonizing excess neurohormonal activity in heart failure, which translated into better functional capacity and quality of life. Exercise prescription is a mean of assessing and interpreting clinical information and applying the principles of training to develop an appropriate regimen and should be tailored to patient’s clinical condition. Resistance training improves peak VO2, exercise capacity and quality of life in heart failure patients. Both continuous and interval exercise training are linked to better quality of life despite ambiguous results in mortality. The aim of this article is to discuss the benefits of exercise in patients with congestive heart failure, exercise prescription, and exercise program including high-intensity interval training, continuous training and resistance exercise.   Abstrak Gagal jantung adalah salah satu penyakit kardiovaskular yang paling sering ditemui dan merupakan akhir daripada banyak jenis patologi jantung. Intoleransi olahraga dan sesak nafas disertai dengan memburuknya kualitas hidup merupakan beberapa masalah yang sering dihadapi oleh pasien gagal jantung, meskipun telah diberikan pengobatan yang optimal. Latihan olahraga pada gagal jantung secara teoritis dapat memperlambat menurunnya fungsi jantung dengan melawan aktivitas neurohormonal yang meningkat pada kondisi gagal jantung yang dicerminkan dengan kapasitas fungsional dan kualitas hidup yang lebih baik. Preskripsi olahraga meliputi pemeriksaan dan interpretasi dari informasi klinis dan aplikasi dari prinsip latihan untuk membentuk regimen yang sesuai dan harus di sesuaikan dengan keadaan klinis pasien. Latihan beban memperbaiki fungsi VO2 puncak, kapasitas olahraga dan kualitas hidup pada pasien dengan gagal jantung. Kedua metode olahraga baik secara kontinu ataupun interval dihubungkan dengan kualitas hidup yang lebih baik meskipun masih ambigu dalam hal mortalitas. Tujuan artikel ini adalah membahas manfaat latihan fisik pada pasien dengan gagal jantung kongestif, cara peresepan serta membahas program high intensity interval training, continuous training serta latihan beban.


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