scholarly journals A prospective observational cohort study considering the feasibility and tolerability of high intensity interval training as a novel treatment therapy for patients with intermittent claudication

2020 ◽  
Author(s):  
Sean Pymer ◽  
Said Ibeggazene ◽  
Joanne Palmer ◽  
George E. Smith ◽  
Amy E. Harwood ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Intermittent Claudication ◽  
High Intensity ◽  
Exercise Prescription ◽  
Interval Training ◽  
Walking Distance ◽  
Completion Rates ◽  
High Intensity Interval Training ◽  
High Intensity Interval

AbstractBackgroundUptake and completion rates for supervised exercise programmes (SEP) for patients with intermittent claudication (IC) are low. Current exercise prescription is a one size fits all approach, based on claudication pain thresholds, potentially limiting individual benefits. High-intensity interval training (HIIT) has the potential to overcome these barriers as it is a more time-efficient, objectively prescribed exercise programme. This study aimed to assess a novel HIIT programme for patients with IC in terms of safety, feasibility, tolerability and indicators of efficacy.Design/MethodsPatients referred to a usual-care SEP were invited to undertake an alternative HIIT programme. All recruited patients performed a baseline cardiopulmonary exercise test (CPET), to inform their exercise prescription. HIIT involved ten, one-minute high-intensity intervals on a stationary cycle ergometer interspersed with one-minute recovery intervals, performed three times per week for six-weeks. Outcomes included safety, feasibility, tolerability, walking distance and quality of life (QoL).Results144 patients with IC were referred, 95 met initial eligibility criteria (66%) and 30 (32%) were recruited for HIIT, of which 15 (50%) completed. Of the recruited patients, 90% were on optimal medical therapy and 40% had concomitant cardiac, cerebrovascular and/or respiratory disease.One serious adverse event was recorded and patients who completed the programme attended 100% of the sessions. Improvements in walking distances and quality of life were observed. Following recruitment of the first 20 patients, the inclusion criteria was refined on the basis of CPET, leading to improved completion rates.ConclusionThe study provides preliminary findings indicating that patients with IC can complete a short-term HIIT programme. HIIT also appears safe, well-tolerated and although not formally powered, walking distances and QoL appear to improve following HIIT. Further research to evaluate the role of HIIT in patients with IC seems warranted.

scholarly journals Exercise training in heart failure: role, prescription and program

2018 ◽  
Vol 38 (4) ◽  
pp. 226-233
Author(s):  
Raymond Pranata ◽  
Emir Yonas ◽  
Bambang B. Siswanto ◽  
Budhi S. Purwowiyoto
Keyword(s):  
Quality Of Life ◽  
Heart Failure ◽  
Exercise Training ◽  
High Intensity ◽  
Exercise Prescription ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Continuous Training ◽  
High Intensity Interval

Heart failure is one of the most common cardiovascular diseases and is a final pathway of various cardiac pathologies. Exercise intolerance and dyspnea accompanied by dete­riorating quality of life are common issues in those suffering from heart failure and may persist despite optimal medical therapy. Exercise training in heart failure theoretically helps to slow down the deterioration of the heart by antagonizing excess neurohormonal activity in heart failure, which translated into better functional capacity and quality of life. Exercise prescription is a mean of assessing and interpreting clinical information and applying the principles of training to develop an appropriate regimen and should be tailored to patient’s clinical condition. Resistance training improves peak VO2, exercise capacity and quality of life in heart failure patients. Both continuous and interval exercise training are linked to better quality of life despite ambiguous results in mortality. The aim of this article is to discuss the benefits of exercise in patients with congestive heart failure, exercise prescription, and exercise program including high-intensity interval training, continuous training and resistance exercise.   Abstrak Gagal jantung adalah salah satu penyakit kardiovaskular yang paling sering ditemui dan merupakan akhir daripada banyak jenis patologi jantung. Intoleransi olahraga dan sesak nafas disertai dengan memburuknya kualitas hidup merupakan beberapa masalah yang sering dihadapi oleh pasien gagal jantung, meskipun telah diberikan pengobatan yang optimal. Latihan olahraga pada gagal jantung secara teoritis dapat memperlambat menurunnya fungsi jantung dengan melawan aktivitas neurohormonal yang meningkat pada kondisi gagal jantung yang dicerminkan dengan kapasitas fungsional dan kualitas hidup yang lebih baik. Preskripsi olahraga meliputi pemeriksaan dan interpretasi dari informasi klinis dan aplikasi dari prinsip latihan untuk membentuk regimen yang sesuai dan harus di sesuaikan dengan keadaan klinis pasien. Latihan beban memperbaiki fungsi VO2 puncak, kapasitas olahraga dan kualitas hidup pada pasien dengan gagal jantung. Kedua metode olahraga baik secara kontinu ataupun interval dihubungkan dengan kualitas hidup yang lebih baik meskipun masih ambigu dalam hal mortalitas. Tujuan artikel ini adalah membahas manfaat latihan fisik pada pasien dengan gagal jantung kongestif, cara peresepan serta membahas program high intensity interval training, continuous training serta latihan beban.

High-intensity interval training improves cardiovascular health, exercise capacity, and quality of life in permanent atrial fibrillation: a case study

2015 ◽  
Vol 40 (12) ◽  
pp. 1321-1323 ◽  
Author(s):  
Jennifer L. Reed ◽  
Pablo B. Nery ◽  
David H. Birnie ◽  
Heather E. Tulloch ◽  
Andrew L. Pipe
Keyword(s):  
Quality Of Life ◽  
Atrial Fibrillation ◽  
High Intensity ◽  
Cardiovascular Health ◽  
Treatment Options ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
Permanent Atrial Fibrillation ◽  
High Intensity Interval

Persons with permanent atrial fibrillation experience reduced exercise tolerance, weight gain, and an associated decline in overall health. We report on a 74-year-old man with permanent atrial fibrillation who underwent a 10-week high-intensity interval training program. Substantial improvements in heart rate, blood pressure, aerobic and functional capacity, and quality of life were observed. These are desirable as these patients are not candidates for other treatment options and more effective therapies for the treatment of atrial fibrillation are needed.

scholarly journals Effects of high-intensity interval training on fatigue and quality of life in testicular cancer survivors

2018 ◽  
Vol 118 (10) ◽  
pp. 1313-1321 ◽  
Author(s):  
Scott C Adams ◽  
Darren S DeLorey ◽  
Margie H Davenport ◽  
Adrian S Fairey ◽  
Scott North ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Testicular Cancer ◽  
Cancer Survivors ◽  
High Intensity ◽  
Interval Training ◽  
High Intensity Interval Training ◽  
High Intensity Interval ◽  
Testicular Cancer Survivors

scholarly journals High INtensity Interval Training In pATiEnts with intermittent claudication (INITIATE): protocol for a multicentre, proof-of-concept, prospective interventional study

BMJ Open ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. e038825
Author(s):  
Sean Pymer ◽  
Amy Harwood ◽  
Said Ibeggazene ◽  
Gordon McGregor ◽  
Chao Huang ◽  
...  
Keyword(s):  
Intermittent Claudication ◽  
High Intensity ◽  
Interval Training ◽  
Walking Distance ◽  
Peak Power Output ◽  
Service Research ◽  
Proof Of Concept ◽  
High Intensity Interval Training ◽  
Supervised Exercise ◽  
High Intensity Interval

IntroductionThe first-line recommended treatment for patients with intermittent claudication (IC) is a supervised exercise programme (SEP), which includes a minimum of 2-hours of exercise per week over a 12-week period. However, provision, uptake and adherence rates for these SEP programmes are poor, with time constraints cited as a common participant barrier. High-intensity interval training (HIIT) is more time-efficient and therefore has the potential to overcome this barrier. However, evidence is lacking for the role of HIIT in those with IC. This proof-of-concept study aims to consider the safety, feasibility, tolerability and acceptability of a HIIT programme for patients with IC.Methods and analysisThis multicentre, single-group, prospective, interventional feasibility study will recruit 40 patients with IC, who will complete 6 weeks of HIIT, 3 times a week. HIIT will involve a supervised programme of 10×1 min high-intensity cycling intervals at 85%–90% peak power output (PPO), interspaced with 10×1 min low intensity intervals at 20%–25% PPO. PPO will be determined from a baseline cardiopulmonary exercise test (CPET) and it is intended that patients will achieve ≥85% of maximum heart rate from CPET, by the end of the second HIIT interval. Primary outcome measures are safety (occurrence of adverse events directly related to the study), programme feasibility (including participant eligibility, recruitment and completion rates) and HIIT tolerability (ability to achieve and maintain the required intensity). Secondary outcomes include patient acceptability, walking distance, CPET cardiorespiratory fitness measures and quality of life outcomes.Ethics and disseminationEthical approval was obtained via a local National Health Service research ethics committee (Bradford Leeds – 18/YH/0112) and recruitment began in August 2019 and will be completed in October 2020. Results will be published in peer-reviewed journals and presented at international conferences and are expected to inform a future pilot randomised controlled trial of HIIT versus usual-care SEPs.Trial registration numberNCT04042311; Pre-results.

scholarly journals A pilot study examining the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular risk factors in cancer survivors

PeerJ ◽  
2016 ◽  
Vol 4 ◽  
pp. e2613 ◽  
Author(s):  
Kellie Toohey ◽  
Kate L. Pumpa ◽  
Leonard Arnolda ◽  
Julie Cooke ◽  
Desmond Yip ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Risk Factors ◽  
High Intensity ◽  
Interval Training ◽  
Moderate Intensity ◽  
High Intensity Interval Training ◽  
Low Volume ◽  
High Intensity Interval ◽  
Intensity Training

PurposeThe aim of this study was to evaluate the effects of low-volume high-intensity interval training and continuous low to moderate intensity training on quality of life, functional capacity and cardiovascular disease risk factors in cancer survivors.MethodsCancer survivors within 24 months post-diagnosis were randomly assigned into the low-volume high-intensity interval training group (n = 8) or the continuous low to moderate intensity training group (n = 8) group for 36 sessions (12 weeks) of supervised exercise. The low-volume high-intensity interval training (LVHIIT) group performed 7 × 30 s intervals (≥85% maximal heart rate) and the continuous low to moderate intensity training (CLMIT) group performed continuous aerobic training for 20 min (≤55% maximal heart rate) on a stationary bike or treadmill.ResultsSignificant improvements (time) were observed for 13 of the 23 dependent variables (ES 0.05–0.61,p ≤ 0.05). An interaction effect was observed for six minute walk test (18.53% [32.43–4.63] ES 0.50,p ≤ 0.01) with the LVHIIT group demonstrating greater improvements.ConclusionThese preliminary findings suggest that both interventions can induce improvements in quality of life, functional capacity and selected cardiovascular disease risk factors. The LVHIIT program was well tolerated by the participants and our results suggest that LVHIIT is the preferred modality to improve fitness (6MWT); it remains to be seen which intervention elicits the most clinically relevant outcomes for patients. A larger sample size with a control group is required to confirm the significance of these findings.

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