scholarly journals TRADITIONAL MEDICINAL SYSTEMS FOR TREATMENT OF DIABETES MELLITUS: A REVIEW

2018 ◽  
Vol 10 (5) ◽  
pp. 7
Author(s):  
Dimple . ◽  
Ashwani Kumar ◽  
Vikas Kumar ◽  
Vidisha Tomer
Keyword(s):  
Diabetes Mellitus ◽  
Functional Foods ◽  
Medical Science ◽  
Herbal Medicines ◽  
Diabetes Treatment ◽  
Active Components ◽  
The World ◽  
Increasing Trend ◽  
Current Scenario ◽  
Treatment Of Diabetes

Diabetes mellitus (DM) is a chronic disease which has clinched the world. More than 300 million people of the world are suffering from this disease and the number is still increasing at a rapid rate as modern medical science has no permanent solution for the disease. Current scenario of the nutraceuticals has increased patient’s faith on the traditional medicinal system and world nutraceutical industry is estimated to reach $285.0 billion by 2021. The increasing trend of nutraceuticals in diabetes treatment makes it important to collect the traditional knowledge of medicines under one heading as it can help researchers to formulate new functional foods and nutraceuticals which can either lower down the risk or cure DM. In addition, the discussion of market available food products, their active components and possible health benefits can help the patients to understand the herbal medicines in a better way.

Association and treatment of diabetes in patients affected by Covid-19

2020 ◽  
Vol 11 (SPL1) ◽  
pp. 1198-1201
Author(s):  
Syed Yasir Afaque
Keyword(s):  
Diabetes Mellitus ◽  
Prognostic Value ◽  
Heart Diseases ◽  
The Novel ◽  
The World ◽  
Treatment Of Diabetes ◽  
Coronavirus Infection ◽  
Composite Outcomes ◽  
Novel Coronavirus ◽  
The Impact

In December 2019, a unique coronavirus infection, SARS-CoV-2, was first identified in the province of Wuhan in China. Since then, it spread rapidly all over the world and has been responsible for a large number of morbidity and mortality among humans. According to a latest study, Diabetes mellitus, heart diseases, Hypertension etc. are being considered important risk factors for the development of this infection and is also associated with unfavorable outcomes in these patients. There is little evidence concerning the trail back of these patients possibly because of a small number of participants and people who experienced primary composite outcomes (such as admission in the ICU, usage of machine-driven ventilation or even fatality of these patients). Until now, there are no academic findings that have proven independent prognostic value of diabetes on death in the novel Coronavirus patients. However, there are several conjectures linking Diabetes with the impact as well as progression of COVID-19 in these patients. The aim of this review is to acknowledge about the association amongst Diabetes and the novel Coronavirus and the result of the infection in such patients.

scholarly journals Glycogen Phosphorylase-a is a Common Target for Anti-Diabetic Effect of Iridoid and Secoiridoid Glycosides

2013 ◽  
Vol 16 (4) ◽  
pp. 530 ◽  
Author(s):  
Hitesh B Vaidya ◽  
Abeer A Ahmed ◽  
Ramesh K Goyal ◽  
Sukhinder K Cheema
Keyword(s):  
Diabetes Mellitus ◽  
Medicinal Plants ◽  
Glycogen Phosphorylase ◽  
Docking Studies ◽  
Chemical Components ◽  
Active Components ◽  
Active Chemical ◽  
Treatment Of Diabetes ◽  
Secoiridoid Glycosides ◽  
Common Target

Purpose. Diabetes mellitus is characterized by hyperglycemia resulting from defects in insulin secretion, action or both. The use of medicinal plants for the treatment of diabetes mellitus dates back from the Ebers papyrus of about 1550 B.C. One of the major problems with herbal drugs is that the active ingredients are not well defined. It is important to know the active components and their molecular interactions which will help to analyze their therapeutic efficacy and also to standardize the product. There are a number of medicinal plants known for their anti-diabetic effect that possess similarities in their active chemical components, e.g. iridoid and secoiridoid glycosides. Methods. In this study, we have compared the structure of various iridoid and secoiridoid glycosides to design a novel pharmacophore. We further developed a structure-activity relationship for the inhibition of glycogen phosphorylase-a. Conclusion. By using docking studies, we are proposing, for the first time, that inhibition of glycogen phosphorylase-a activity is a common target for iridoids and secoiridoids to elicit anti-diabetic effects. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.

scholarly journals PATHYAPATHYA IN PRAMEHA

2021 ◽  
Vol 9 (8) ◽  
pp. 1806-1814
Author(s):  
Ripsa Raj K. P ◽  
P Sudhakar Reddy
Keyword(s):  
Diabetes Mellitus ◽  
Scientific Explanation ◽  
Medical Science ◽  
Great Influence ◽  
Clinical Entity ◽  
Causative Factors ◽  
The World ◽  
Growing Population

Diabetes mellitus is becoming the fastest considerable disease in the world. India has been estimated with the fast- est-growing population of Diabetics. According to International Diabetic Federation (IDF), the total number of Diabetic subjects will be around 151 million in India by 2045. The clinical entity of Prameha can be correlated with Diabetes Mellitus. It is considered a Lifestyle disorder, the food, drinks and sedentary habits are having a great influence on this disorder. In Ayurveda classics elaborately mentioned the Nidana (causative factors) and Pathya ahara (wholesome food & drinks) and Apathya ahara (unwholesome food & drinks), Pathya Vihara (Conducive lifestyle) and Apathya Vihara (Non-Conducive lifestyle) of Prameha. The classification of Prameha as per Susruta Samhita as Apathya nimittaja Prameha and Beeja doshaja Prameha indicates the importance of Ahara and Vihara in prevention as well as management of this disease. In this article, a sincere attempt has been made to incorporate the principles of Ayurveda and Modern medical science with a scientific explanation regarding Pathya (Diet) and Vihara (lifestyle) in Prameha (Diabetes Mellitus). Keywords: Pathya, Apathya, Prameha, Ahara, Vihara.

A Systematic Review of the Medicinal Potential of Mulberry in Treating Diabetes Mellitus

2018 ◽  
Vol 46 (08) ◽  
pp. 1743-1770 ◽  
Author(s):  
Helin Wei ◽  
Siyuan Liu ◽  
Yijun Liao ◽  
Chuanhui Ma ◽  
Dongying Wang ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Herbal Medicines ◽  
Glucose Absorption ◽  
Future Research ◽  
Asian Countries ◽  
Active Components ◽  
Challenges And Opportunities ◽  
Research Findings ◽  
Anti Inflammation ◽  
Promising Therapeutic Agent

Diabetes mellitus (DM) is a serious metabolic disorder which has reached epidemic proportions all over the world. Despite tremendous developments in medicinal chemistry, traditional medicine is still commonly used for the prevention and treatment of DM. Traditional herbal medicines have played a major role in the management of DM in Asian countries. In particular, mulberry has commonly been utilized in China for the treatment of DM for thousands of years. In the last decade, numerous preclinical findings have suggested that mulberry is a promising therapeutic agent for the treatment of DM, and the polyhydroxylated alkaloids, flavonoids and polysaccharides from mulberry may be the potential active components. The present review systematically summarizes the chemical composition of mulberry and the pharmacological effects of different medicinal parts on DM; these effects include influences on glucose absorption, insulin (INS) production/secretion, anti-oxidation and anti-inflammation processes. After summarizing our research findings, we will discuss the challenges and opportunities and explore the direction of future research and the potential for developing mulberry into pharmaceuticals for the widespread treatment of DM.

scholarly journals The Efficacy of Optimism: Benefit Finding in the Treatment of Diabetes in Iranian Patients

ISRN Nursing ◽  
2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Hossein Karimi Moonaghi ◽  
Hossein Namdar Areshtanab ◽  
Leila Jouybari
Keyword(s):  
Diabetes Mellitus ◽  
Chronic Disease ◽  
Middle Eastern ◽  
Benefit Finding ◽  
The World ◽  
Treatment Of Diabetes ◽  
Lack Of Exercise ◽  
The Many ◽  
Iranian Patients

The incidence of diabetes mellitus is on the rise around the world. Middle Eastern countries will be facing a vast increase in the number of diabetes mellitus cases by 2030. Diagnosis of a chronic disease such as diabetes mellitus can be a shocking and life-altering event. Conversely, a diagnosis of a chronic illness can also offer the patient opportunities to change unhealthy behaviors such as poor diet, smoking, and lack of exercise, making them healthier than before their diagnosis. This is referred to as “benefit finding”. This study reveals the many benefit findings of Iranian patients who have been diagnosed with diabetes mellitus and illustrates how benefit finding can be an integral part of long-term patient care.

scholarly journals Indonesian plants with potential as an anti-diabetes mellitus agent

2020 ◽  
Vol 1 (2) ◽  
pp. 28-31
Author(s):  
Rachmat Hidayat ◽  
Lusia Hayati ◽  
Nita Parisa
Keyword(s):  
Diabetes Mellitus ◽  
Antioxidant Activity ◽  
Natural Antioxidants ◽  
Pancreatic Tissue ◽  
Oh Groups ◽  
Rat Pancreas ◽  
The World ◽  
Long Time ◽  
Treatment Of Diabetes ◽  
Phenolic Oh Groups

Diabetes Mellitus (DM) is a degenerative disease that continues to increase in numberin Indonesia and is a disease that is spread throughout the world due to unbalancednutritional conditions. Treatment of diabetes mellitus is a chronic and lifelongtreatment. Treatment of diabetes mellitus, such as the use of insulin and oralantihyperglycemia drugs, is relatively expensive, is used for a long time and can causeunwanted side effects. There are many plants that have potential as antihyperglycemiadrugs. One of the active compounds that act as antihyperglycemia isflavonoids.Flavonoids derived from various types of plants studied are thought to actas antihyperglycemic agents. Flavonoids are known to have the ability to scavenge freeradicals or act as natural antioxidants. The antioxidant activity of flavonoids is relatedto phenolic –OH groups which can capture or neutralize free radicals (such as ROS orRNS). Flavonoids can play a role in pancreatic tissue damage caused by DNA alkylationdue to alloxan induction as a result of improving the morphology of the rat pancreas(Prameswari and Widjanarko, 2014).

scholarly journals Inhibition of the α-glucosidase enzyme from Pelawan stem extract (Tristaniopsis merguensis Griff)

2021 ◽  
Vol 926 (1) ◽  
pp. 012001
Author(s):  
R G Mahardika ◽  
G P Kusuma ◽  
O Roanisca ◽  
Henri
Keyword(s):  
Diabetes Mellitus ◽  
Negative Impact ◽  
Herbal Medicines ◽  
The Body ◽  
Raw Material ◽  
Total Phenolic ◽  
Methanol Fraction ◽  
Stem Extract ◽  
Treatment Of Diabetes ◽  
Synthetic Drug

Abstract Diabetes mellitus continues to increase along with the increasing pattern of consuming ready-to-eat foods. The consequences of this habit will have a negative impact on the health of the body so that it can cause death. Treatment of diabetes mellitus is carried out in various ways, including administration of insulin and synthetic drug therapy. However, this medication has dangerous side effects. Therefore, research was carried out on Pelawan stems (Tristaniopsis merguensis Griff) which have the potential to be associated with secondary metabolites and bioactivity as antidiabetic so that they can be considered as raw material for herbal medicines in the future. total phenolic content of the methanol fraction of T. merguensis stems is 176.37 mg GAE/g DW. The total flavonoid content of the methanol fraction of T. merguensis stems is 9.85 mg QE/g DW. The results of the antidiabetic test for the methanol fraction of T. merguensis stems obtained an IC50 of 5.31 μg/mL. When viewed from the qualitative results of phenolics and flavonoids that have been carried out, it is likely that the activity of the α-glucosidase enzyme in this study is more influenced by polyphenolic compounds.

scholarly journals A Case Report of Diabetes Mellitus Type 2 with Adjuvant Use of Bauhinia forficata in Pharmacological Treatment

2020 ◽  
pp. 49-56
Author(s):  
Igor Domingos de Souza ◽  
Eliza Miranda Ramos ◽  
Francisco José Mendes dos Reis ◽  
Hugo Miguel Ramos Vieira ◽  
Iara Barbosa Ramos ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Case Report ◽  
Herbal Medicines ◽  
Postprandial Glucose ◽  
Human Organism ◽  
Diabetic Patients ◽  
Unified Health System ◽  
Treatment Of Diabetes ◽  
Bauhinia Forficata

Introduction: Bauhinia forficata, has presented in several interesting effects for the diabetic human organism as the adjuvant treatment. Its effects have been tested and proven in scientific studies in the Unified Health System in Brazil. Aims: Verify the effects of the medicinal plant Bauhinia forficata as an aid in the control of glycemic indexes. Methodology: Case report with exploratory descriptive study with a quantitative approach, using direct observation techniques of the Dáder method adapted to the use of herbal medicines such as Bauhinia forficata.  Results: In this study, there was a decrease in triglyceride levels with a drop of 77%, which despite not reaching the recommended values ​​for diabetic patients (<150 mg/dl) is quite significant. Conclusion: Bauhinia forficata used in the treatment of diabetes mellitus has anti-inflammatory actions that contribute to reduce glycated hemoglobin and, thus decrease fasting and postprandial glucose.

To the treatment of diabetes mellitus with insulin

2021 ◽  
Vol 20 (1) ◽  
pp. 96-97
Author(s):  
R. Luria
Keyword(s):  
Diabetes Mellitus ◽  
Carbohydrate Metabolism ◽  
Insulin Treatment ◽  
Modern Theory ◽  
Diabetes Treatment ◽  
Treatment Of Diabetes

Among the numerous studies on the effect of insulin, discovered by Banting, a hormone that regulates carbohydrate metabolism, of course, observations deserve special attention. Noogdenʹa, one of the creators of the modern theory of diabetes. No Orden and Isaac (Klin. Woch., 1923, No. 43) summarize their observations of 50 insulin-treated diabetics. The authors emphasize from the outset that the superiority of insulin treatment over other methods of diabetes treatment is beyond question, both in terms of the effect on glycosuria and in relation to acidosis.

scholarly journals A DETAILED OVERVIEW OF MEDICINAL PLANTS HAVING HYPOGLYCEMIC ACTIVITY

2016 ◽  
Vol 8 (2) ◽  
pp. 139 ◽  
Author(s):  
Sandra Celine ◽  
Shawn Tomy ◽  
Ujwala TK ◽  
Sam Johnson Udaya Chander
Keyword(s):  
Diabetes Mellitus ◽  
Herbal Medicine ◽  
Chemical Constituents ◽  
Herbal Medicines ◽  
Developed Countries ◽  
Cerebrovascular Diseases ◽  
World Health ◽  
The World ◽  
After Cancer ◽  
Health Organization

Diabetes mellitus represents a spectrum of metabolic disorder, which has become one of the major public health concerns worldwide. Diabetes mellitus has emerged as a third leading killer after cancer and cardiovascular/cerebrovascular diseases and India has a distinction of having largest number of diabetics in world second to China. Herbal medicine for treating chronic diseases, especially diabetes has gained an exponential growth in the last few years and both developing and developed countries are adopting herbal drugs for treatment of diabetes mellitus. The World Health Organization (WHO) has listed 21,000 plants, which are used for medicinal purposes around the world. The WHO has defined herbal medicines as finished labelled medicinal products that contain aerial or underground parts of the plants or other plant material or combination thereof as active ingredients, whether in crude state or as plant preparations. This review attempts to present the profiles of plants with hypoglycemic properties, reported in the literature with proper categorization according to the botanical name, family, parts used, chemical constituents, and its other uses. Relevant medical databases and websites were searched. To qualify for inclusion, the herbs should have confirmed hypoglycemic potential. Other criteria for inclusion are: published in English and peer-reviewed journals. We also used related keywords like diabetes mellitus, plant, herb, glycemic control, natural or herbal medicine, Ayurvedic plants, and hypoglycemic plants, as keywords or combination of them. A total of 151 herbs belonging to 72 families were outlined in this review.

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