scholarly journals Nipah Virus – Thread to Pregnancy

2018 ◽  
Vol 6 (5) ◽  
pp. 66-70
Author(s):  
Sujeet Kumar ◽  
Shubham BHATIA ◽  
Amit Sharma ◽  
Neelam Painuly
Keyword(s):  
Nipah Virus ◽  
Infected Person ◽  
Zoonotic Virus ◽  
The Family ◽  
Positive Person

Nipah virus is a type of zoonotic virus. Which cause serious respiratory nervous problems along with serious fever it get easily transmitted to one infected person to another person. Nipah virus is a great thread to mankind. Nipah virus belong to the family of Paramyxoviridae. Nipah virus positive person is called as NiV positive pigs various birds are also effected by the virus badly. So the study and proper knowledge about Nipah virus should be their.

scholarly journals Mapping of domains responsible for nucleocapsid protein–phosphoprotein interaction of henipaviruses

2004 ◽  
Vol 85 (6) ◽  
pp. 1675-1684 ◽  
Author(s):  
Y. P. Chan ◽  
C. L. Koh ◽  
S. K. Lam ◽  
L.-F. Wang
Keyword(s):  
Amino Acid ◽  
Binding Site ◽  
Binding Sites ◽  
Nucleocapsid Protein ◽  
New Genus ◽  
Nipah Virus ◽  
Hendra Virus ◽  
Protein Blotting ◽  
The Family ◽  
Overlay Assay

Hendra virus (HeV) and Nipah virus (NiV) are members of a new genus, Henipavirus, in the family Paramyxoviridae. Each virus encodes a phosphoprotein (P) that is significantly larger than its counterparts in other known paramyxoviruses. The interaction of this unusually large P with its nucleocapsid protein (N) was investigated in this study by using recombinant full-length and truncated proteins expressed in bacteria and a modified protein-blotting protein-overlay assay. Results from our group demonstrated that the N and P of both viruses were able to form not only homologous, but also heterologous, N–P complexes, i.e. HeV N was able to interact with NiV P and vice versa. Deletion analysis of the N and P revealed that there were at least two independent N-binding sites on P and they resided at the N and C termini, respectively. Similarly, more than one P-binding site was present on N and one of these was mapped to a 29 amino acid (aa) C-terminal region, which on its own was sufficient to interact with the extreme C-terminal 165 aa region of P.

scholarly journals In Pandemic Situation the Work Carried on Covid-19 Origin and their Mandatory Treatment with Precaution

2021 ◽  
pp. 739-743
Author(s):  
A. J. Giri ◽  
A. N. Salve ◽  
J. K. Dhumal ◽  
P. R. Doifode ◽  
Aijaz A. Sheikh ◽  
...  
Keyword(s):  
Sore Throat ◽  
Incubation Period ◽  
Clinical Features ◽  
Depth Information ◽  
Infected Person ◽  
Disease Epidemiology ◽  
Treatment And Prevention ◽  
Close Interaction ◽  
The Family ◽  
Difficulty Breathing

In present study, COVID-19 is a type of coronavirus disease belonging to the family Corona viridae. The disease is thought to originate from bats and was spread to people through an unknown medium in Wuhan, China. Ideally, the condition is spread by mouthful of air or close interaction with infected droplets that have an incubation period between two and fourteen days. Today, there are thousands of infections and deaths that have been caused by the disease. Moreover, the symptoms of the disease include fever, cough, sneezing, sore throat, difficulty breathing, and tiredness. Additionally, the diagnosis of the disease starts by gathering samples of the upper and lower respiratory tracts of the infected person. This paper provides in-depth information on COVID-19 as it discusses the disease epidemiology, transmission, clinical features, diagnosis, treatment and prevention.

scholarly journals Nipah virus (NiV): a ‘new’ addition to the ever changing landscape of infections

2018 ◽  
Vol 8 (2) ◽  
pp. 725-726
Author(s):  
Sruthi James ◽  
Indrajit Banerjee ◽  
Brijesh Sathian ◽  
Edwin Van Teijlingen
Keyword(s):  
Public Health ◽  
Disease Burden ◽  
Public Health Surveillance ◽  
Rna Virus ◽  
Nipah Virus ◽  
Emerging Viruses ◽  
Fruit Bat ◽  
Public Health Professionals ◽  
The Family ◽  
Effective System

Public Health professionals and researchers always need to be on their toes as the pool of viruses is forever changing.  One recent example of this change is the Nipah virus (NiV).  This infection is a type of zoonosis, emerging from the family of Paramyxoviridae, genus Henipavirus (RNA virus) and the natural host is Pteropus fruit bat. For Public Health surveillance and multidisciplinary approaches on investigations and therapy and development of vaccines are vital.  As with all emerging viruses harmful to humans, an effective system for the detection of infectious diseases as well as for the identification for new causes, risk factors and characteristics in challenged settings is crucial to reduce the disease burden in the population.

scholarly journals The obscure impact of Nipah virus

Bionatura ◽  
2019 ◽  
Vol 4 (1) ◽  
Author(s):  
Anupam Saha ◽  
Biplab Debnath
Keyword(s):  
Preventive Measures ◽  
Close Contact ◽  
Nipah Virus ◽  
Deep Impact ◽  
The Family ◽  
The World ◽  
Infection Disease ◽  
Hazard Factor

The motivation behind this introduction is to feature the known and deep impact subjected to the Nipah Virus (NiV). Principally concentrating on preventive measures and the treatment of the Nipah Virus. NiV is an individual from the family Paramyxoviridae, class Henipavirus. NiV was at first recognized in 1999, amid a flare-up of Encephalitis and respiratory sickness among pig ranchers and individuals with close contact with pigs in Malaysia and Singapore. Nipah infection caused a generally gentle ailment in pigs, yet almost 300 human cases with more than 100 passings were accounted for in 1999. Not just in Malaysia its spread around the world. A case-controlled survey ponder is directed to decide word related hazard factors for disease. Contact with live pigs, earmarks of being the essential hazard factor for human Nipah infection disease. Coordinate contact with life, possibly contaminated pigs ought to be limited to forestall transmission of this conceivably lethal ZOONOSIS to people. Understanding the significance and in light of specific records, it is an endeavor to assemble it to diagram the qualities and to be worried about this issue. This essential survey is gone for giving a knowledge into this fatal flare-up and to bring it into concern.

scholarly journals Henipavírus: Paramixovírus Zoonóticos, Emergentes e Letais

2021 ◽  
Vol 25 (2) ◽  
pp. 136-143
Author(s):  
Gabriela Molinari Darold ◽  
Glaucenyra Cecília Pinheiro da Silva ◽  
Átila Insfran Ocampos ◽  
Lorraine Gabriela Trettene ◽  
Daniella Aparecida Godoi Kemper ◽  
...  
Keyword(s):  
Nipah Virus ◽  
High Capacity ◽  
Relevant Information ◽  
Hendra Virus ◽  
Ecological Niches ◽  
Genetic Constitution ◽  
Domestic Species ◽  
Terrestrial Mammals ◽  
The Family ◽  
Pandemic Threat

Hendra henipavírus (HeV) e Nipah henipavírus (NiV) são membros do gênero Henipavirus, pertencente à família Paramyxoviridae, sendo classificados como patógenos de nível de biossegurança 4, em função de sua alta capacidade em causar doença letal em seres humanos associada à constituição genética única, carência de terapia e profilaxia específicas. O reservatório natural destes vírus são os morcegos pertencentes ao gênero Pteropus, encontrados em regiões que se estendem do Pacífico Ocidental à Costa Leste da África. O desmatamento é um dos responsáveis pela saída dos morcegos de seus nichos ecológicos e aproximação de fazendas e vilarejos. Novos casos de infecção pelo HeV em cavalos continuam ocorrendo na Austrália, enquanto o NiV é responsável por surtos anuais em humanos, desde 2001, na Índia e Bangladesh. O NiV, em particular, possui vários recursos que destacam seu potencial como ameaça pandêmica, incluindo sua capacidade de infectar humanos diretamente, a partir de reservatórios naturais, além de uma capacidade limitada de transmissão entre seres humanos. Apesar disso, atualmente, pouco se sabe sobre os mecanismos pelos quais os morcegos abrigam vírus capazes de causar doenças tão graves em outros mamíferos terrestres. A presente revisão traz informações relevantes para o entendimento sobre a epidemiologia destas viroses, a patogenia nas espécies suscetíveis, bem como a importância destes vírus nas espécies domésticas, principalmente, nos equídeos. Palavras-chave: Hendra Vírus. Nipah Vírus. Morcegos. Equinos. Suínos. Abstract Hendra henipavirus (HeV) and Nipah henipavirus (NiV) are members of the genus Henipavirus, belonging to the family Paramyxoviridae, being classified as biosafety level 4 pathogens, due to their high capacity to cause lethal disease in humans associated with their unique genetic constitution, lack of specific therapy and prophylaxis. Bats belonging to the genus Pteropus, found in regions that extend from the Western Pacific to the East coast of Africa, are natural reservoir of such viruses. Deforestation is one of the factors responsible for the bats’ leaving their ecological niches and their adaptation to farms and villages. New cases of HeV infection in horses continue to occur in Australia while NiV has been responsible for annual human outbreaks since 2001 in India and Bangladesh. NiV has several features that highlight its potential as a pandemic threat, including its ability to infect humans directly from natural reservoirs, as well as a limited capacity for transmission between humans. Despite this, little is currently known about the mechanisms by which bats harbor viruses capable of causing serious diseases in other terrestrial mammals. This review provides relevant information for understanding the epidemiology of these viruses, the pathogenesis in susceptible species, as well as the importance of these viruses in domestic species, especially in horses. Keywords: Hendra Virus. Nipah Virus. Bats. Horses. Pigs.

scholarly journals Nipah virus, a paramyxovirus that emerges from wildlife hosts and represent a threat to human health

2018 ◽  
pp. 7089-7090
Author(s):  
Salim Mattar ◽  
Marco González-Tous ◽  
Luis Salgado Arroyo
Keyword(s):  
Human Health ◽  
High Mortality ◽  
Respiratory Diseases ◽  
Nipah Virus ◽  
Mortality Rates ◽  
The Family

The Nipah virus (NiV) belongs to the family Paramyxoviridae, genus Henipavirus and has recently been recognized as causing serious diseases with high mortality rates in humans. In 1999, NiV was identified in Malaysia during an outbreak of encephalitis and respiratory diseases in pigs and in people responsible for the care of these animals,

scholarly journals V protein, the virulence factor across the family Paramyxoviridae: a review

2019 ◽  
pp. 73-85
Author(s):  
May Ling Tham ◽  
Khatijah Yusoff ◽  
Sarah Othman ◽  
Suet Lin Chia
Keyword(s):  
Measles Virus ◽  
Sendai Virus ◽  
Nipah Virus ◽  
Host Cells ◽  
V Protein ◽  
Signal Transducers ◽  
Stat Proteins ◽  
Animal Pathogens ◽  
The Family ◽  
Interferon Antagonists

Paramyxoviridae is a family of viruses within the order Mononegavirales and comprises 14 genera; Metaavulavirus, Orthoavulavirus, Paraavulavirus, Synodonvirus, Ferlavirus, Aquaparamyxovirus, Henipavirus, Morbillivirus, Respirovirus, Jeilongvirus, Narmovirus, Salemvirus, Pararubulavirus and Orthorubulavirus. The members within this family are negative and single-stranded RNA viruses including human and animal pathogens such as measles virus (MeV), Nipah virus (NiV), mumps virus (MuV), Sendai virus (SeV) and Newcastle disease virus (NDV). The V protein is conserved within the family and plays an essential role in viral pathogenicity. Although V proteins of many paramyxoviruses are interferon-antagonists which counteract with the host’s innate immunity, there are still differences in the mode of action of the V protein between different genera or species within the same genera. The strategies to circumvent the host interferon (IFN) pathway can be divided into three general mechanisms; degradation of signal transducers and activators of transcription (STAT) protein, inhibition of phosphorylation of the transcription factor and, inhibition of translocation of STAT proteins into the nucleus. As a result, inhibition of IFN signalling and production promotes viral replication in the host cells. This review highlights the mechanism of the paramyxoviral V protein in evading the host IFN system.

scholarly journals Nipah Virus (Niv): 21st Century Novel Emerging Zoonotic Virus with Pandemic Potential

2019 ◽  
Vol 8 (07) ◽  
pp. 2633-2640
Author(s):  
R. Manikandan ◽  
M. Dinesh ◽  
E. Kalaiselvan ◽  
V. Chandran ◽  
V. Praveen ◽  
...  
Keyword(s):  
21St Century ◽  
Nipah Virus ◽  
Zoonotic Virus

Ultrastructural Studies of Nipah Virus, A Newly Emergent Paramyxovirus, Using Thin Section, Negative Stain, Immunogold, and in Situ Hybridization Electron Microscopy

2000 ◽  
Vol 6 (S2) ◽  
pp. 644-645
Author(s):  
Cynthia S. Goldsmith ◽  
Toni Whistler ◽  
Pierre E. Rollin ◽  
Kaw Bing Chua ◽  
William Bellini ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Cerebral Spinal Fluid ◽  
Nipah Virus ◽  
Neurologic Disease ◽  
Human Patient ◽  
Ultrastructural Studies ◽  
Negative Stain ◽  
The Family ◽  
Abattoir Workers

An increase in cases of acute febrile encephalitis occurred in Western Malaysia between September 1998 and May 1999, and a similar illness was reported in Singapore in March 1999. Most cases occurred in males who had been exposed to pigs, or among abattoir workers, and at least 100 deaths were reported. The illness was characterized by fever and headache, followed by drowsiness and disorientation; patients with severe cases developed seizures and coma within 24 to 48 hours. Concurrently, there were also illnesses and deaths among pigs in the same region, although the symptoms predominantly involved the respiratory system, and only a few pigs had signs of neurologic disease. From a cerebral spinal fluid specimen from a human patient, Dr. Chua and colleagues were successful in isolating a virus that was morphologically identified as belonging to the family Paramyxoviridae, and is now known as Nipah virus.

scholarly journals ICTV Virus Taxonomy Profile: Paramyxoviridae

2019 ◽  
Vol 100 (12) ◽  
pp. 1593-1594 ◽  
Author(s):  
Bert Rima ◽  
Anne Balkema-Buschmann ◽  
William G. Dundon ◽  
Paul Duprex ◽  
Andrew Easton ◽  
...  
Keyword(s):  
Measles Virus ◽  
Rna Viruses ◽  
Nipah Virus ◽  
International Committee ◽  
Mumps Virus ◽  
Hendra Virus ◽  
Virus Taxonomy ◽  
Link Type ◽  
Parainfluenza Viruses ◽  
The Family

The family Paramyxoviridae consists of large enveloped RNA viruses infecting mammals, birds, reptiles and fish. Many paramyxoviruses are host-specific and several, such as measles virus, mumps virus, Nipah virus, Hendra virus and several parainfluenza viruses, are pathogenic for humans. The transmission of paramyxoviruses is horizontal, mainly through airborne routes; no vectors are known. This is a summary of the current International Committee on Taxonomy of Viruses (ICTV) Report on the family Paramyxoviridae. which is available at ictv.global/report/paramyxoviridae.

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