scholarly journals Efficient qubit phase estimation using adaptive measurements

Quantum ◽  
2021 ◽  
Vol 5 ◽  
pp. 467
Author(s):  
Marco A. Rodríguez-García ◽  
Isaac Pérez Castillo ◽  
P. Barberis-Blostein
Keyword(s):  
State Of The Art ◽  
Phase Estimation ◽  
Quantum Metrology ◽  
Quantum Phases ◽  
Likelihood Functions ◽  
Current State ◽  
Wide Range ◽  
Adaptive Measurements ◽  
Cramer Rao Bound ◽  
Quantum Parameter Estimation

Estimating correctly the quantum phase of a physical system is a central problem in quantum parameter estimation theory due to its wide range of applications from quantum metrology to cryptography. Ideally, the optimal quantum estimator is given by the so-called quantum Cramér-Rao bound, so any measurement strategy aims to obtain estimations as close as possible to it. However, more often than not, the current state-of-the-art methods to estimate quantum phases fail to reach this bound as they rely on maximum likelihood estimators of non-identifiable likelihood functions. In this work we thoroughly review various schemes for estimating the phase of a qubit, identifying the underlying problem which prohibits these methods to reach the quantum Cramér-Rao bound, and propose a new adaptive scheme based on covariant measurements to circumvent this problem. Our findings are carefully checked by Monte Carlo simulations, showing that the method we propose is both mathematically and experimentally more realistic and more efficient than the methods currently available.

scholarly journals Introduction to redundancy rules: the continuous wavelet transform comes of age

2018 ◽  
Vol 376 (2126) ◽  
pp. 20170258 ◽  
Author(s):  
Paul S. Addison
Keyword(s):  
Wavelet Transform ◽  
Continuous Wavelet Transform ◽  
State Of The Art ◽  
Structural Characteristics ◽  
Continuous Wavelet ◽  
Theme Issue ◽  
Current State ◽  
Analysis Methods ◽  
Wide Range ◽  
New Form

Redundancy: it is a word heavy with connotations of lacking usefulness. I often hear that the rationale for not using the continuous wavelet transform (CWT)—even when it appears most appropriate for the problem at hand—is that it is ‘redundant’. Sometimes the conversation ends there, as if self-explanatory. However, in the context of the CWT, ‘redundant’ is not a pejorative term, it simply refers to a less compact form used to represent the information within the signal. The benefit of this new form—the CWT—is that it allows for intricate structural characteristics of the signal information to be made manifest within the transform space, where it can be more amenable to study: resolution over redundancy. Once the signal information is in CWT form, a range of powerful analysis methods can then be employed for its extraction, interpretation and/or manipulation. This theme issue is intended to provide the reader with an overview of the current state of the art of CWT analysis methods from across a wide range of numerate disciplines, including fluid dynamics, structural mechanics, geophysics, medicine, astronomy and finance. This article is part of the theme issue ‘Redundancy rules: the continuous wavelet transform comes of age’.

scholarly journals Mosaic Super-resolution via Sequential Feature Pyramid Networks

2019 ◽  
Author(s):  
Mehrdad Shoeiby ◽  
Mohammad Ali Armin ◽  
Sadegh Aliakbarian ◽  
Saeed Anwar ◽  
Lars petersson
Keyword(s):  
State Of The Art ◽  
Super Resolution ◽  
Autonomous Driving ◽  
Single Shot ◽  
Current State ◽  
Wide Range ◽  
Feature Pyramid ◽  
Novel Method ◽  
Convolutional Lstm ◽  
Mosaic Images

<div>Advances in the design of multi-spectral cameras have</div><div>led to great interests in a wide range of applications, from</div><div>astronomy to autonomous driving. However, such cameras</div><div>inherently suffer from a trade-off between the spatial and</div><div>spectral resolution. In this paper, we propose to address</div><div>this limitation by introducing a novel method to carry out</div><div>super-resolution on raw mosaic images, multi-spectral or</div><div>RGB Bayer, captured by modern real-time single-shot mo-</div><div>saic sensors. To this end, we design a deep super-resolution</div><div>architecture that benefits from a sequential feature pyramid</div><div>along the depth of the network. This, in fact, is achieved</div><div>by utilizing a convolutional LSTM (ConvLSTM) to learn the</div><div>inter-dependencies between features at different receptive</div><div>fields. Additionally, by investigating the effect of different</div><div>attention mechanisms in our framework, we show that a</div><div>ConvLSTM inspired module is able to provide superior at-</div><div>tention in our context. Our extensive experiments and anal-</div><div>yses evidence that our approach yields significant super-</div><div>resolution quality, outperforming current state-of-the-art</div><div>mosaic super-resolution methods on both Bayer and multi-</div><div>spectral images. Additionally, to the best of our knowledge,</div><div>our method is the first specialized method to super-resolve</div><div>mosaic images, whether it be multi-spectral or Bayer.</div><div><br></div>

scholarly journals Climate-dependent propagation of precipitation uncertainty into the water cycle

2020 ◽  
Author(s):  
Ali Fallah ◽  
Sungmin O ◽  
Rene Orth
Keyword(s):  
Hydrological Model ◽  
Water Cycle ◽  
State Of The Art ◽  
Rain Gauge ◽  
Multiple Sources ◽  
Current State ◽  
Wide Range ◽  
The Impact ◽  
Conceptual Hydrological Model

Abstract. Precipitation is a crucial variable for hydro-meteorological applications. Unfortunately, rain gauge measurements are sparse and unevenly distributed, which substantially hampers the use of in-situ precipitation data in many regions of the world. The increasing availability of high-resolution gridded precipitation products presents a valuable alternative, especially over gauge-sparse regions. Nevertheless, uncertainties and corresponding differences across products can limit the applicability of these data. This study examines the usefulness of current state-of-the-art precipitation datasets in hydrological modelling. For this purpose, we force a conceptual hydrological model with multiple precipitation datasets in > 200 European catchments. We consider a wide range of precipitation products, which are generated via (1) interpolation of gauge measurements (E-OBS and GPCC V.2018), (2) combination of multiple sources (MSWEP V2) and (3) data assimilation into reanalysis models (ERA-Interim, ERA5, and CFSR). For each catchment, runoff and evapotranspiration simulations are obtained by forcing the model with the various precipitation products. Evaluation is done at the monthly time scale during the period of 1984–2007. We find that simulated runoff values are highly dependent on the accuracy of precipitation inputs, and thus show significant differences between the simulations. By contrast, simulated evapotranspiration is generally much less influenced. The results are further analysed with respect to different hydro-climatic regimes. We find that the impact of precipitation uncertainty on simulated runoff increases towards wetter regions, while the opposite is observed in the case of evapotranspiration. Finally, we perform an indirect performance evaluation of the precipitation datasets by comparing the runoff simulations with streamflow observations. Thereby, E-OBS yields the best agreement, while furthermore ERA5, GPCC V.2018 and MSWEP V2 show good performance. In summary, our findings highlight a climate-dependent propagation of precipitation uncertainty through the water cycle; while runoff is strongly impacted in comparatively wet regions such as Central Europe, there are increasing implications on evapotranspiration towards drier regions.

scholarly journals AI-driven deep CNN approach for multi-label pathology classification using chest X-Rays

2021 ◽  
Vol 7 ◽  
pp. e495
Author(s):  
Saleh Albahli ◽  
Hafiz Tayyab Rauf ◽  
Abdulelah Algosaibi ◽  
Valentina Emilia Balas
Keyword(s):  
Neural Networks ◽  
Data Augmentation ◽  
State Of The Art ◽  
Synthetic Data ◽  
X Rays ◽  
Deep Convolutional Neural Networks ◽  
Current State ◽  
Pathology Classification ◽  
Wide Range ◽  
Multi Class Classification

Artificial intelligence (AI) has played a significant role in image analysis and feature extraction, applied to detect and diagnose a wide range of chest-related diseases. Although several researchers have used current state-of-the-art approaches and have produced impressive chest-related clinical outcomes, specific techniques may not contribute many advantages if one type of disease is detected without the rest being identified. Those who tried to identify multiple chest-related diseases were ineffective due to insufficient data and the available data not being balanced. This research provides a significant contribution to the healthcare industry and the research community by proposing a synthetic data augmentation in three deep Convolutional Neural Networks (CNNs) architectures for the detection of 14 chest-related diseases. The employed models are DenseNet121, InceptionResNetV2, and ResNet152V2; after training and validation, an average ROC-AUC score of 0.80 was obtained competitive as compared to the previous models that were trained for multi-class classification to detect anomalies in x-ray images. This research illustrates how the proposed model practices state-of-the-art deep neural networks to classify 14 chest-related diseases with better accuracy.

scholarly journals Biomarkers of adverse drug reactions

2017 ◽  
Vol 243 (3) ◽  
pp. 291-299 ◽  
Author(s):  
Daniel F Carr ◽  
Munir Pirmohamed
Keyword(s):  
Pharmaceutical Industry ◽  
Adverse Drug Reactions ◽  
State Of The Art ◽  
Tissue Injury ◽  
Healthcare Providers ◽  
Drug Reactions ◽  
Circulating Biomarkers ◽  
Current State ◽  
Organ Systems ◽  
Wide Range

Adverse drug reactions can be caused by a wide range of therapeutics. Adverse drug reactions affect many bodily organ systems and vary widely in severity. Milder adverse drug reactions often resolve quickly following withdrawal of the casual drug or sometimes after dose reduction. Some adverse drug reactions are severe and lead to significant organ/tissue injury which can be fatal. Adverse drug reactions also represent a financial burden to both healthcare providers and the pharmaceutical industry. Thus, a number of stakeholders would benefit from development of new, robust biomarkers for the prediction, diagnosis, and prognostication of adverse drug reactions. There has been significant recent progress in identifying predictive genomic biomarkers with the potential to be used in clinical settings to reduce the burden of adverse drug reactions. These have included biomarkers that can be used to alter drug dose (for example, Thiopurine methyltransferase (TPMT) and azathioprine dose) and drug choice. The latter have in particular included human leukocyte antigen (HLA) biomarkers which identify susceptibility to immune-mediated injuries to major organs such as skin, liver, and bone marrow from a variety of drugs. This review covers both the current state of the art with regard to genomic adverse drug reaction biomarkers. We also review circulating biomarkers that have the potential to be used for both diagnosis and prognosis, and have the added advantage of providing mechanistic information. In the future, we will not be relying on single biomarkers (genomic/non-genomic), but on multiple biomarker panels, integrated through the application of different omics technologies, which will provide information on predisposition, early diagnosis, prognosis, and mechanisms. Impact statement • Genetic and circulating biomarkers present significant opportunities to personalize patient therapy to minimize the risk of adverse drug reactions. ADRs are a significant heath issue and represent a significant burden to patients, healthcare providers, and the pharmaceutical industry. • This review details the current state of the art in biomarkers of ADRs (both genetic and circulating). There is still significant variability in patient response which cannot be explained by current knowledge of genetic risk factors for ADRs; however, we discussed how specific advances in genomics have the potential to yield better and more predictive models. • Many current clinically utilized circulating biomarkers of tissue injury are valid biomarkers for a number of ADRs. However, they often give little insight into the specific cell or tissue subtype which may be affected. Emerging circulating biomarkers with potential to provide greater information on the etiology/pathophysiology of ADRs are described.

scholarly journals Tensile Testing of Soils: History, Equipment and Methodologies

2020 ◽  
Vol 6 (3) ◽  
pp. 591-601
Author(s):  
Ausamah Al Houri ◽  
Ahed Habib ◽  
Ahmed Elzokra ◽  
Maan Habib
Keyword(s):  
Tensile Strength ◽  
State Of The Art ◽  
Retaining Walls ◽  
Tensile Tests ◽  
Testing Methods ◽  
Embankment Dams ◽  
Current State ◽  
Wide Range ◽  
Indirect Tensile ◽  
And Behavior

Tensile strength of soil is indeed one of the important parameters to many civil engineering applications. It is related to wide range of cracks specially in places such as slops, embankment dams, retaining walls or landfills. Despite of the fact that tensile strength is usually presumed to be zero or negligible, its effect on the erosion and cracks development in soil is significant. Thus, to study the tensile strength and behavior of soil several techniques and devices were introduced. These testing methods are classified into direct and indirect ways depending on the loading conditions. The direct techniques including c-shaped mold and 8-shaped mold are in general complicated tests and require high accuracy as they are based on applying a uniaxial tension load directly to the specimen. On the other hand, the indirect tensile tests such as the Brazilian, flexure beam, double punch and hollow cylinder tests provide easy ways to assess the tensile strength of soil under controlled conditions. Although there are many studies in this topic the current state of the art lack of a detailed article that reviews these methodologies. Therefore, this paper is intended to summarize and compare available tests for investigating the tensile behavior of soils.

scholarly journals Nanostructured Gas Sensors for Medical and Health Applications: Low to High Dimensional Materials

Biosensors ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 43 ◽  
Author(s):  
Noushin Nasiri ◽  
Christian Clarke
Keyword(s):  
Patient Outcomes ◽  
Gas Sensors ◽  
State Of The Art ◽  
Promising Candidate ◽  
Human Breath ◽  
Non Invasive ◽  
Current State ◽  
Specificity And Sensitivity ◽  
Wide Range ◽  
Health Applications

Human breath has long been known as a system that can be used to diagnose diseases. With advancements in modern nanotechnology, gas sensors can now diagnose, predict, and monitor a wide range of diseases from human breath. From cancer to diabetes, the need to treat at the earliest stages of a disease to both increase patient outcomes and decrease treatment costs is vital. Therefore, it is the promising candidate of rapid and non-invasive human breath gas sensors over traditional methods that will fulfill this need. In this review, we focus on the nano-dimensional design of current state-of-the-art gas sensors, which have achieved records in selectivity, specificity, and sensitivity. We highlight the methods of fabrication for these devices and relate their nano-dimensional materials to their record performance to provide a pathway for the gas sensors that will supersede.

Detection of Corrosion in Offshore Risers Using Guided Ultrasonic Waves

2007 ◽  
Author(s):  
Graham R. Edwards ◽  
Tat-Hean Gan
Keyword(s):  
Test Performance ◽  
State Of The Art ◽  
Development Programme ◽  
Guided Wave ◽  
Ultrasonic Waves ◽  
Splash Zone ◽  
Future Developments ◽  
Current State ◽  
Wide Range ◽  
Offshore Risers

Guided wave ultrasonics is now an established technology for detecting corrosion in pipes. The technique is principally applied to pipe that is insulated, buried or otherwise inaccessible to conventional NDT. TWI has experience in applying the technique to offshore risers, where there are specific problems. Access beneath the cut-off valves of the platform is restricted and the clamps used to hold the riser and the coatings used to protect it in the splash zone can affect test performance. This paper will describe these problems in detail and discuss ways of overcoming them. Case studies will be used to illustrate the current state-of-the-art and TWI’s research and development programme in long range ultrasonics for inspecting a wide range of components from pipes to railway lines will highlight future developments.

scholarly journals Modern neurooncology – the development of the field and the possibilities of glioma therapy in Warsaw – a neurosurgical perspective

2019 ◽  
Vol 2019 (30) ◽  
pp. 135-141
Author(s):  
Bartosz Czapski ◽  
Adam Warzecha ◽  
Wojciech Górecki ◽  
Tomasz Wójcikiewicz ◽  
Mirosław Ząbek
Keyword(s):  
Brain Tumors ◽  
Brain Cancer ◽  
State Of The Art ◽  
Clinical Problem ◽  
Complex Nature ◽  
Scientific Cooperation ◽  
Malignant Brain Tumors ◽  
Current State ◽  
Wide Range

This article is devoted to discussing the possibility of treating malignant brain tumors in the Mazovia region. The difficult clinical problem confronted by doctors and scientists is discussed in relation to the complex nature of gliomas. The current state-of-the-art treatment along with its limitations is subjected to discussion. The opportunities available to Mazovian doctors, which can be used to significantly prolong and improve the quality of patients’ lives, are presented in detail. Finally, the paper presents the wide range of possibilities for scientific cooperation and the directions it should take in order to learn more about the genesis of brain cancer and make it curable.

scholarly journals Climate-dependent propagation of precipitation uncertainty into the water cycle

2020 ◽  
Author(s):  
Ali Fallah Maraghi ◽  
Sungmin Oh ◽  
Rene Orth
Keyword(s):  
Hydrological Modeling ◽  
Hydrological Model ◽  
Water Cycle ◽  
State Of The Art ◽  
Rain Gauge ◽  
Multiple Sources ◽  
Current State ◽  
Wide Range ◽  
The Impact

&lt;p&gt;Precipitation is a crucial variable for hydro-meteorological applications. Unfortunately, rain gauge measurements are sparse and unevenly distributed, which substantially hampers the use of in-situ precipitation data in many regions of the world. The increasing availability of high-resolution gridded precipitation products presents a valuable alternative, especially over gauge-sparse regions. Nevertheless, uncertainties and corresponding differences across products can limit the applicability of these data. This study examines the usefulness of current state-of-the-art precipitation datasets in hydrological modeling. For this purpose, we force a conceptual hydrological model with multiple precipitation datasets in &gt;200 European catchments. We consider a wide range of precipitation products, which are generated via (1) interpolation of gauge measurements (E-OBS and GPCC V.2018), (2) data assimilation into reanalysis models (ERA-Interim, ERA5, and CFSR) and (3) combination of multiple sources (MSWEP V2). For each catchment, runoff and evapotranspiration simulations are obtained by forcing the model with the various precipitation products. Evaluation is done at the monthly time scale during the period of 1984-2007. We find that simulated runoff values are highly dependent on the accuracy of precipitation inputs, and thus show significant differences between the simulations. By contrast, simulated evapotranspiration is generally much less influenced. The results are further analysed with respect to different hydro-climatic regimes. We find that the impact of precipitation uncertainty on simulated runoff increases towards wetter regions, while the opposite is observed in the case of evapotranspiration. Finally, we perform an indirect performance evaluation of the precipitation datasets by comparing the runoff simulations with streamflow observations. Thereby, E-OBS yields the best agreement, while furthermore ERA5, GPCC V.2018 and MSWEP V2 show good performance. In summary, our findings highlight a climate-dependent propagation of precipitation uncertainty through the water cycle; while runoff is strongly impacted in comparatively wet regions such as Central Europe, there are increasing implications on evapotranspiration towards drier regions.&lt;/p&gt;

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