scholarly journals Determinan Penyakit Asma pada Pekerja Usia Produktif di Indonesia, Riset Kesehatan Dasar 2013

2018 ◽  
Vol 46 (1) ◽  
pp. 11-22
Author(s):  
Lusianawaty Tana
Keyword(s):  
Nutritional Status ◽  
Respiratory Diseases ◽  
Healthy Lifestyle ◽  
Productivity Loss ◽  
Eastern Region ◽  
Fuel Type ◽  
Significance Level ◽  
Chronic Respiratory Diseases ◽  
Complex Sample ◽  
Residence Location

AbstractAsthma is one of the chronic respiratory diseases that often leads to decrease of productivity, loss ofincome and unemployment, as well as psychosocial and financial problems. The objective of the researchwas to identify the determinants of asthma of productive age workers in Indonesia using Basic HealthResearch (Riskesdas 2013). Sampling criteria were workers aged 15-64 years across the country. Thedata were analyzed by complex sample with significance level of 0.05 and 95% confidence intervals.Samples that met the criteria were 405.984 people. Determinants of asthma were areas of residence,age, education, nutritional status, smoking, illumination sources, sex, occupation, ownership index,residence location, slum neighborhood, physical activity, and fuel type usage. (OR adj 1.1-2.1 p≤0.01).The proportion of asthma in eastern region of Indonesia and Java-Bali region were 2.05 and 1.75 higherthan Sumatra region respectively. Less nutritional status had asthma proportion of 1.5 times higher thannormal. Improving nutritional status and increasing knowledge about healthy lifestyle should be done asan effort to reduce the occurrence of asthma.Key words: workers, asthma, Indonesia, Riskesdas 2013   AbstrakAsma merupakan masalah kesehatan di semua Negara dan salah satu penyakit saluran pernapasankronik yang sering mengakibatkan turunnya produktifitas, hilangnya pendapatan income dan pekerjaan,serta menimbulkan masalah psikososial dan keuangan. Tujuan analisis lanjut menentukan determinanpenyakit asma pada pekerja usia produktif di Indonesia, menggunakan data Riskesdas Tahun 2013.Kriteria sampel: berusia 15-64 tahun dan status bekerja. Variabel yang di analisis meliputi asma,karakteristik individu, perilaku, dan tempat tinggal. Analisis data menggunakan kompleks sampel,tingkat kemaknaan ≤0,05 dan confidence interval 95%. Jumlah sampel sesuai kriteria 405.984 orang.Determinan asma adalah kawasan tempat tinggal, umur, pendidikan, status gizi, merokok, sumberpenerangan, jenis kelamin, pekerjaan utama, indeks kepemilikan, lokasi tempat tinggal, lingkungankumuh, aktivitas fisik, dan jenis bahan bakar. (ORadj 1,1-2,1 p≤0,01). Persentase asma lebih tinggi diKawasan Timur Indonesia 2,05 kali dan Jawa-Bali 1,75 kali dibandingkan Sumatera, pada status gizikurang 1,5 kali dibandingkan normal, umur 55-64 tahun 1,5 kali dibandingkan umur 15-24 tahun, padapendidikan rendah 1,5 kali dibandingkan pendidikan tinggi. Perbaikan status gizi dan peningkatanpengetahuan tentang hidup sehat perlu dilakukan sebagai upaya menurunkan kejadian asma.Kata kunci: pekerja, asma, Indonesia, Riskesdas 2013

CRISPR/Cas9 Genome Editing Tool: A Promising Tool for Therapeutic Applications on Respiratory Diseases

2020 ◽  
Vol 20 (5) ◽  
pp. 333-346
Author(s):  
Sadiya Bi Shaikh ◽  
Yashodhar Prabhakar Bhandary
Keyword(s):  
Respiratory Diseases ◽  
Gene Editing ◽  
Epithelial Mesenchymal Transition ◽  
Respiratory Health ◽  
Chronic Obstructive ◽  
Therapeutic Tool ◽  
Obstructive Pulmonary Disease ◽  
Mesenchymal Transition ◽  
Chronic Respiratory Diseases ◽  
Promising Tool

Respiratory diseases are one of the prime topics of concern in the current era due to improper diagnostics tools. Gene-editing therapy, like Clustered regularly interspaced palindromic repeats- associated nuclease 9 (CRISPR/Cas9), is gaining popularity in pulmonary research, opening up doors to invaluable insights on underlying mechanisms. CRISPR/Cas9 can be considered as a potential gene-editing tool with a scientific community that is helping in the advancement of knowledge in respiratory health and therapy. As an appealing therapeutic tool, we hereby explore the advanced research on the application of CRISPR/Cas9 tools in chronic respiratory diseases such as lung cancer, Acute respiratory distress syndrome (ARDS) and cystic fibrosis (CF). We also address the urgent need to establish this gene-editing tool in various other lung diseases such as asthma, Chronic obstructive pulmonary disease (COPD) and Idiopathic pulmonary fibrosis (IPF). The present review introduces CRISPR/Cas9 as a worthy application in targeting epithelial-mesenchymal transition and fibrinolytic system via editing specific genes. Thereby, based on the efficiency of CRISPR/Cas9, it can be considered as a promising therapeutic tool in respiratory health research.

From Genesis To Revelation: The Role Of Inflammatory Mediators In Chronic Respiratory Diseases And Their Control By Nucleic Acid-Based Drugs

2016 ◽  
Vol 13 (999) ◽  
pp. 1-1 ◽  
Author(s):  
Sante Di Gioia ◽  
Carla Sardo ◽  
Stefano Castellani ◽  
Barbara Porsio ◽  
Giuliana Belgiovine ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Inflammatory Mediators ◽  
Respiratory Diseases ◽  
Chronic Respiratory Diseases

Interleukin-17A: A Potential Therapeutic Target in Chronic Lung Diseases

2019 ◽  
Vol 19 (7) ◽  
pp. 921-928 ◽  
Author(s):  
Sadiya Bi Shaikh ◽  
Ashwini Prabhu ◽  
Yashodhar Prabhakar Bhandary
Keyword(s):  
Respiratory Diseases ◽  
Inflammatory Cytokine ◽  
Inflammatory Responses ◽  
Chronic Obstructive ◽  
Interleukin 17 ◽  
Potential Therapeutic Target ◽  
Chronic Respiratory Diseases ◽  
Chronic Lung Diseases ◽  
Interleukin 17A ◽  
Insight Into

Background: Interleukin-17A (IL-17A) is a pro-inflammatory cytokine that has gained a lot of attention because of its involvement in respiratory diseases. Interleukin-17 cytokine family includes six members, out of which, IL-17A participates towards the immune responses in allergy and inflammation. It also modulates the progression of respiratory disorders. Objective: The present review is an insight into the involvement and contributions of the proinflammatory cytokine IL-17A in chronic respiratory diseases like Idiopathic Pulmonary Fibrosis (IPF), Chronic Obstructive Pulmonary Distress (COPD), asthma, pneumonia, obliterative bronchiolitis, lung cancer and many others. Conclusion: IL-17A is a major regulator of inflammatory responses. In all the mentioned diseases, IL- 17A plays a prime role in inducing the diseases, whereas the lack of this pro-inflammatory cytokine reduces the severity of respective respiratory diseases. Thereby, this review suggests IL-17A as an instrumental target in chronic respiratory diseases.

Non-Communicable Diseases and Global Health Politics

2019 ◽  
pp. 626-659
Author(s):  
Roger Magnusson
Keyword(s):  
Respiratory Diseases ◽  
Communicable Diseases ◽  
World Health ◽  
Global Response ◽  
Non Communicable Diseases ◽  
Health Politics ◽  
Chronic Respiratory Diseases ◽  
Health Organization ◽  
High Level ◽  
And Control

Non-communicable diseases (NCDs), including cardiovascular disease, cancer, chronic respiratory diseases, and diabetes, are responsible for around 70 percent of global deaths each year. This chapter describes how NCDs have become prevalent and critically evaluates global efforts to address NCDs and their risk factors, with a particular focus on the World Health Organization (WHO) and United Nations (UN) system. It explores the factors that have prevented those addressing NCDs from achieving access to resources and a priority commensurate with their impact on people’s lives. The chapter evaluates the global response to NCDs both prior to and since the UN High-Level Meeting on Prevention and Control of Non-communicable Diseases, held in 2011, and considers opportunities for strengthening that response in future.

scholarly journals Workplace nutrition habits in Slovenian small and middle sized enterprises

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
S Percic ◽  
M Stubelj
Keyword(s):  
Chronic Diseases ◽  
Online Survey ◽  
Healthy Lifestyle ◽  
Productivity Loss ◽  
Premature Death ◽  
Average Score ◽  
Workplace Health ◽  
Nutritional Habits ◽  
Healthy Nutrition ◽  
Nutrition Habits

Abstract Background Premature death, chronic diseases, productivity loss and other social and economic concerns can be influenced by healthy lifestyle workplace promotion programs, including healthy nutrition habits. In Slovenia a project called >>STAR-VITAL-healthy ageing at workplace << has been going on since September 2017. Methods The survey results are based on an analysis of 805 respondents from 20 different small and middle sized enterprises in Slovenia. The survey was carried out via both a paper questionnaire and an online survey during the period from June 2019 to February 2020. The screening questionnaire was completed before interventions. We estimated the average score for the eight questions concerning nutritional habits. Results Nutritional habits are the following: 62% respondents eat three or more meals a day, 64% respondents eat vegetables each day, 59,8% respondents eat fruits each day, 31,9% respondents eat fish or see fruits at least once a week, 45,7% respondents eat whole wheats at least once a week, 54,1% respondents eat red meat not more than twice a week, 62,1% respondents eat fried food not more than three times a month and 79,1% respondents drink sweet drinks less than three times a week. The results on question >>What is the most common form of meal you eat while at work? << are the following: purchase meal at restaurant 45,3%, bring from home 32,7%, delivery/carry out 6,2%, do not eat 5,2%, other 4,7%, employer cafeteria 3,9% and vending machine 1,2%. Conclusions The results of our survey show that a significant percentage of the workers in Slovenia still has unhealthy nutritional habits. Assessment of nutritional habits before workplace promotion program interventions allow us to compare which combinations of interventions are the most effective. The results will indicate the strength and weakness of each intervention and how it could be improved. Key messages The population is growing old and chronic diseases increases, which is part of the bad nutritional habits. Healthy lifestile promotion is needed to improve quality of life. The workplace health promoting programs have been shown to be an efficient way of improving workerś health. Implementing promotional program of nutritional habits are proper for Slvenian enterprises.

Sign in / Sign up

Export Citation Format

Share Document