scholarly journals Triple whammy: a rare case of epithelioid hemangioendothelioma with synchronous angiomyomatous hamartoma complicated by Actinomyces meyeri

2021 ◽  
Vol 8 (3) ◽  
pp. 56-61
Author(s):  
Nariman Khan ◽  
◽  
Saadia Waheed ◽  
Rahaf Alkhateb ◽  
◽  
...  
Keyword(s):  
Groin Pain ◽  
Soft Tissues ◽  
Treatment Guidelines ◽  
Epithelioid Hemangioendothelioma ◽  
The Body ◽  
Vascular Endothelial ◽  
Imaging Studies ◽  
One Year ◽  
The Right ◽  
Hispanic Male

Epithelioid hemangioendothelioma is a rare vascular malignancy that originates from vascular endothelial or pre-endothelial cells and is composed of epithelioid or histiocytoid cells. This malignancy has an incidence of approximately one per one million individuals and can occur in various regions of the body including the lungs, liver, bones, and soft tissues. The behavior of this cancer can range from indolent to aggressive and diagnosis and treatment are often delayed due to variable presentations and lack of established treatment guidelines. Here we present the case of a 27-year-old Hispanic male that presented with right groin pain, abdominal pain, and a fifty-pound weight loss over one year. The patient had a complex hospital course during which he was found to have an angiomyomatous hamartoma of his right groin area, postsurgical right inguinal wound infection with Actinomyces meyeri, and epithelioid hemangioendothelioma distal to the right iliac bifurcation. The patient is currently pending further imaging studies to evaluate candidacy for surgical resection and following with oncology for chemotherapeutic options.

scholarly journals Metastatic cutaneous epithelioid hemangioendothelioma involving right atrium - a case report

2016 ◽  
Vol 3 (3) ◽  
pp. 47
Author(s):  
Sandy Mpho Mosenye ◽  
Rahul Daimari ◽  
Neha Sharma ◽  
Princess Lelani Chikanda ◽  
Feng Zhou ◽  
...  
Keyword(s):  
Right Atrium ◽  
Cardiac Involvement ◽  
Soft Tissues ◽  
Vascular Tumor ◽  
Epithelioid Hemangioendothelioma ◽  
Malignant Potential ◽  
Vascular Endothelial ◽  
Rare Occurrence ◽  
Scalp Lesion ◽  
The Common

Epithelioid hemangioendothelioma (EHE) is a rare vascular endothelial tumour with unpredictable malignant potential. The common sites involved are the lung, liver and soft tissues; with cardiac involvement being a very rare occurrence. The diagnosis of this rare vascular tumor is made by typical histopathological findings and confirmed by specific immunohistochemistry. We present a case of a patient with a long standing painless scalp lesion who presented with pulmonary symptoms and ultimately diagnosed to have metastatic cutaneous EHE involving the lungs, pericardium and right atrium.

scholarly journals A Case of Vanishing Metastatic Mass: Right Atrial Mass in the Setting of Primary Epithelioid Hemangioendothelioma of the Spine

2018 ◽  
Vol 11 (2) ◽  
pp. 534-540 ◽  
Author(s):  
Eshan Patel ◽  
P. Kancharla ◽  
B.K. Surapaneni ◽  
K. Hennrick ◽  
M. Goldfinger ◽  
...  
Keyword(s):  
Clinical Presentation ◽  
Epithelioid Hemangioendothelioma ◽  
The Body ◽  
Right Atrial ◽  
Low Grade ◽  
Vascular Neoplasm ◽  
Right Atrial Mass ◽  
Progression Of Disease ◽  
The Right ◽  
Age And Sex

Epithelioid hemangioendothelioma (EHE) is a rare low-grade vascular neoplasm that is characterized as intermediate between benign hemangioma and high-grade angiosarcoma affecting 1 in 1,000,000 people worldwide. It has been described throughout the body with lung, liver, skin, and bone being the most frequent sites. Primary EHE of the spine has been reported in 56 cases so far with no correlation of age and sex. Our case highlights a rare clinical presentation, etiopathogenesis, diagnosis, and treatment of EHE of the spine with metastasis to the right atrium. This is the first documented case of EHE of the spine with metastatic spread to the heart treated with bevacizumab leading to resolution of the heart metastatic mass. Further studies are warranted to develop a treatment formula for this rare tumor, to consider combination chemotherapy and new adjuvant targeted immunotherapies to prevent progression of disease.

Calcifying fibrous tumour originating from the right cardiac ventricle in a child

2013 ◽  
Vol 24 (1) ◽  
pp. 161-163 ◽  
Author(s):  
Ben Zhang ◽  
Weida Zhang ◽  
Xiaowu Wang
Keyword(s):  
Right Ventricle ◽  
Soft Tissues ◽  
The Body ◽  
Dystrophic Calcification ◽  
Cardiac Ventricle ◽  
The Right

AbstractCalcifying fibrous tumour is a rare benign fibrous lesion. It is paucicellular, with fibroblasts, dense collagenisation, psammomatous and dystrophic calcification, and patchy lymphoplasmacytic infiltrates. Calcifying fibrous tumour was first described in subcutaneous and deep soft tissues, and has been reported all over the body. However, calcifying fibrous tumour originating from the heart is extremely rare. This article describes the case of a giant calcifying fibrous tumour arising from the right ventricle in a child, where the tumour was totally resected and no recurrence was observed during a 4-year follow-up period.

A case of peripheral primitive neuroectodermal tumor of the ovary

2004 ◽  
Vol 14 (2) ◽  
pp. 370-372 ◽  
Author(s):  
K.-J. Kim ◽  
B.-W. Jang ◽  
S.-K. Lee ◽  
B.-K. Kim ◽  
S.-L. Nam
Keyword(s):  
Primitive Neuroectodermal Tumor ◽  
Soft Tissues ◽  
Case Reports ◽  
The Body ◽  
Neuroectodermal Tumor ◽  
Pelvic Cavity ◽  
Age Group ◽  
Peripheral Primitive Neuroectodermal Tumor ◽  
Children And Young Adults ◽  
The Right

Peripheral primitive neuroectodermal tumor (PNET) belongs to the PNET/Ewing's sarcoma family. PNET is a small round cell tumor of putative neuroectoderm origin and is the second most common sarcoma among children and young adults. It may occur anywhere in the body and within any age group; however, it is most likely to occur in the bone and soft tissues. There have been a small number of case reports of PNET arising in the ovary. We presented a case of PNET arising in the right ovary of an 18-year-old woman. The tumor was metastased to the lymph nodes of the pelvis and para-aorta at surgical staging. We had persecuted Taxol/carboplatin chemotherapy, pelvic cavity radiotherapy, and Vincristine/Actinomycink, Cyclophosphamide/Doxorubicin (VACA). She died after 10 months due to septic shock.

scholarly journals Hepatic Epithelioid Hemangioendothelioma

2018 ◽  
Vol 142 (2) ◽  
pp. 263-267 ◽  
Author(s):  
Lynette L. Studer ◽  
Dale M. Selby
Keyword(s):  
Vascular Endothelial Cells ◽  
Incidental Finding ◽  
Treatment Protocol ◽  
Vascular Tumor ◽  
Metastatic Carcinoma ◽  
Epithelioid Hemangioendothelioma ◽  
The Body ◽  
Fusion Product ◽  
Vascular Endothelial ◽  
Abdominal Symptoms

Epithelioid hemangioendothelioma is a rare vascular tumor, composed of epithelioid and histiocytoid vascular endothelial cells in myxoid or fibrotic stroma, which can arise in multiple locations throughout the body. In the liver, this neoplasm usually presents on imaging as an incidental finding of multifocal, heterogeneously enhancing nodules in both lobes or presents clinically with nonspecific abdominal symptoms. Histologically, the tumor has been mistaken for metastatic carcinoma, angiosarcoma, hepatocellular carcinoma, and cholangiocarcinoma. The neoplasm usually stains positive for vascular markers, such as factor VIII–related antigen, CD31, and CD34, and negative for cytokeratins. The translocation t(1;3)(p36.3;q25), resulting in the CAMTA1-WWTR1 fusion product, is the most commonly identified genetic abnormality with this tumor. Although hepatic epithelioid hemangioendothelioma can have a varied clinical course, it is generally considered less aggressive than angiosarcoma. There is no consensus treatment protocol and techniques including liver transplantation, liver resection, chemotherapy and/or radiation therapy, and surveillance have all been used with varying outcomes.

Xanthogranuloma of the Sciatic Nerve: Case Report

Neurosurgery ◽  
2004 ◽  
Vol 55 (6) ◽  
pp. E1453-E1458 ◽  
Author(s):  
Parag G. Patil ◽  
Thomas J. Cummings ◽  
James A. Nunley ◽  
Allan H. Friedman
Keyword(s):  
Nervous System ◽  
Sciatic Nerve ◽  
Peripheral Nervous System ◽  
Groin Pain ◽  
Clinical Presentation ◽  
Resonance Imaging ◽  
Imaging Studies ◽  
Pathological Characteristics ◽  
First Case ◽  
The Right

Abstract OBJECTIVE AND IMPORTANCE: Xanthogranulomas involving the central or peripheral nervous system are extraordinarily rare. None have been reported in the lower extremity. Here, we report and characterize the first case of xanthogranuloma of the sciatic nerve. CLINICAL PRESENTATION: A 58-year-old woman presented with poorly localized right back and groin pain. Magnetic resonance imaging studies revealed an enhancing lesion of the sciatic nerve in the right gluteal region. INTERVENTION: The sciatic nerve xanthogranuloma was resected without complication. CONCLUSION: Our report indicates that xanthogranuloma, although extremely rare, may occur throughout the nervous system. Our evaluation demonstrates that such lesions involving the peripheral nervous system have similar pathological characteristics to xanthogranulomas that more commonly occur in the skin.

scholarly journals A Case of Newly Diagnosed Klippel Trenaunay Weber Syndrome Presenting with Nephrotic Syndrome

2015 ◽  
Vol 2015 ◽  
pp. 1-4 ◽  
Author(s):  
Egemen Cebeci ◽  
Secil Demir ◽  
Meltem Gursu ◽  
Abdullah Sumnu ◽  
Mehmet Yamak ◽  
...  
Keyword(s):  
Nephrotic Syndrome ◽  
Soft Tissues ◽  
Case Reports ◽  
Renal Involvement ◽  
The Body ◽  
Laboratory Findings ◽  
Weber Syndrome ◽  
Av Malformation ◽  
The Right ◽  
Physical Findings

Klippel Trenaunay Weber syndrome (KTWS) is a rare disease characterized by hemihypertrophy, variceal enlargement of the veins, and arteriovenous (AV) malformations. Renal involvement in KTWS is not known except in rare case reports. Herein, we present a case of KTWS with nephrotic syndrome. A 52-year-old male was admitted due to dyspnea and swelling of the body for the last three months. The pathological physical findings were diffuse edema, decreased lung sounds at the right basal site, increased diameter and decreased length of the left leg compared with the right one, diffuse variceal enlargements, and a few hemangiomatous lesions on the left leg. The pathological laboratory findings were hypoalbuminemia, hyperlipidemia, increased creatinine level (1.23 mg/dL), and proteinuria (7.6 g/day). Radiographic pathological findings were cystic lesions in the liver, spleen, and kidneys, splenomegaly, AV malformation on the left posterolateral thigh, and hypertrophy of the soft tissues of the proximal left leg. He was diagnosed to have KTWS with these findings. Renal biopsy was performed to determine the cause of nephrotic syndrome. The pathologic examination was consistent with focal segmental sclerosis (FSGS). He was started on oral methylprednisolone at the dosage of 1 mg/kg and began to be followedup in the nephrology outpatient clinic.

scholarly journals Simultaneous Hydatid Cyst of the Liver and Left Iliac Fossa: An Unusual Case Report

2019 ◽  
Vol 2019 ◽  
pp. 1-4 ◽  
Author(s):  
Tika Ram Bhandari ◽  
Sudha Shahi
Keyword(s):  
Hydatid Cyst ◽  
Hydatid Disease ◽  
Iliac Fossa ◽  
Elisa Test ◽  
The Body ◽  
Igg Antibody ◽  
Left Iliac Fossa ◽  
Right Lobe ◽  
One Year ◽  
The Right

Hydatid disease is a significant health problem in many livestock-rearing areas especially in the developing world, mainly caused by Echinococcus granulosus. The liver and lung are the most common affected sites. However, hydatid disease can occur anywhere in the body. Simultaneous involvement of two organs or sites is very unusual, mainly for organs other than the lung and liver. We thus report a very unusual combination of hepatic and left iliac fossa with hydatid disease in an adult patient. A 37-year-old farmer from a village presented with intermittent right upper quadrant and left iliac fossa pain associated with distention of abdomen for one month. Abdominal radiological investigations reported hydatid cyst disease; one cyst was found in the right lobe of the liver and another in the left iliac fossa. Positive IgG antibody by the ELISA test also confirmed the diagnosis. Pericystectomy and excision of hydatid cyst without spillage of content for the liver and left iliac fossa were done, respectively. Patient was discharged on the 10th postoperative day with an uneventful postoperative course. There was no recurrence of the lesion during one-year follow-up period. A combination of hydatid disease in the liver and iliac fossa is very unusual, so clinician should have thoughts regarding this rare entity as an important differential diagnosis.

scholarly journals Propanolol as a treatment for deep infantile hemangioma: case report

2021 ◽  
Vol 12 (5) ◽  
pp. 302-304
Author(s):  
Vargas Hernández Víctor Manuel ◽  
Luján-Irastorza Jesús Estuardo ◽  
Durand-Montaño Carlos ◽  
Ávila-Rebollar Daniela ◽  
Ávila-Pérez Felipe de Jesús ◽  
...  
Keyword(s):  
Case Report ◽  
Soft Tissues ◽  
Treatment Guidelines ◽  
Well Being ◽  
Infantile Hemangioma ◽  
Transverse Diameter ◽  
Deep Blue ◽  
Airway Symptoms ◽  
Life Threatening ◽  
The Right

Background: Infantile hemangiomas (IH) are common neoplasms composed of proliferating endothelial cells. The duration and the growth rate are variable; some grow very poorly, while others grow rapidly and at an unpredictable rate. Despite the relative frequency of IH and the possible severity of complications, there are currently no uniform treatment guidelines. Although most are not worrisome, about 12% of IHs are significantly complex; propranolol has been adopted as a treatment. Objective: Report a clinical case of lactanate with hemangioma treated with propranolol. Case report: A healthy newborn is presented, with the presence of small telangiectasias in the right hemicneck without association with obstetric trauma; of a healthy 31-year-old mother; During its evolution at 3 months of age, the area covered with telangiectasias turned deep blue and the growth of a protrusion began, ultrasound and angioresonance, showed soft tissues of the posterior cervical space a lobulated mass of 9.1x4.1x4.9cm in its longitudinal and transverse diameter respectively, diagnosing it as a deep hemangioma; which was treated with propanolol. Discussion: Asymptomatic newborns with infantile neck hemangiomas are clinically controlled for the first six months of life, 60% of them develop life-threatening airway symptoms; the identification of the hemangioma was due to its rapid growth and not due to the alteration of surrounding structures that put the well-being of the infant at risk. Regarding the application of Propranolol, its administration was immediately after its identification, to avoid future complications. Conclusion: administration of propranolol systemically eliminates the characteristic color and reduces the size of the hemangioma.

scholarly journals Demographic and Clinical Profile of Tuberculous Mastitis Patients at Tebet General Hospital, Jakarta

2019 ◽  
Vol 3 (2) ◽  
pp. 32
Author(s):  
Desak Ketut Nari Swari Pramegia ◽  
Rio Putratama Achmad Faried ◽  
Kelvin Setiawan ◽  
Bramastha Aires Rosadi ◽  
Terry Renata Lawanto
Keyword(s):  
General Hospital ◽  
Left Breast ◽  
The Body ◽  
Clinical Profile ◽  
Hiv Test ◽  
Unilateral Involvement ◽  
The Mean ◽  
One Year ◽  
The Right ◽  
Possible Cause

Aim: Objective of the study is to find out the demographic and clinical profile of tuberculous mastitis (TM) patients. Methods: The study was carried out for a period of one year from August 2017 to August 2018 at Tebet General Hospital. Histopathologically diagnosed cases of TM were retrospectively studied. Results: All eight patients diagnosed as suffering from TM were females with the mean age of 37.25 years. Of these, two patients were lactating, six others were not, and 75% were multiparous. Unilateral involvement was observed in all cases. The right breast was affected in 62.5% and left breast in 37.5% cases. Patients presented with a solitary lump on one breast (87.5%), swelling of the breast (37.5%), and breast pain (100%). In the present study, two of the patients had previous positive tuberculosis (TB) contact and more than half found to be below an average economic level. All the patients were negative on the HIV test; also, there was no focus of TB elsewhere in the body. Conclusion: Tuberculosis should be considered as one possible cause of either mastitis or breast abscess. Histopathology examination played an important role in the diagnosis of TM. Standardized sequence for the diagnosis of TM is needed to increase awareness of the disease.

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