scholarly journals Preparation of carbonate apatite scaffolds using different carbonate solution and soaking time

2019 ◽  
Vol 13 (2) ◽  
pp. 139-148 ◽  
Author(s):  
Fadilah Darus ◽  
Mariatti Jaafar ◽  
Nurazreena Ahmad
Keyword(s):  
Compressive Strength ◽  
Aqueous Solutions ◽  
Tricalcium Phosphate ◽  
Average Pore Size ◽  
Carbonate Content ◽  
Precipitation Reaction ◽  
Carbonate Apatite ◽  
Hydrothermal Conversion ◽  
Average Pore ◽  
Beta Tricalcium Phosphate

The aim of this study is to fabricate CO3Ap scaffolds using a dissolution-precipitation reaction during hydrothermal treatment. Beta-tricalcium phosphate (?-TCP) was used as a precursor instead of the commonly used alpha-tricalcium phosphate (?-TCP). Here, the CO3Ap scaffold fabrication was accomplished in two steps: i) fabrication of ?-TCP scaffold using a combination of direct foaming and a sacrificial template and ii) hydrothermal conversion of the ?-TCP scaffold at 200?C in 2mol/l NaHCO3 and Na2CO3 aqueous solutions for 2-10 days. The effect of two different solutions was identified in the dissolution-precipitation reaction. CO3Ap scaffold with 8.95wt.% carbonate content was successfully fabricated using a NaHCO3 solution. The average pore size of the scaffold was approximately 180 ?m with 72% porosity. The average compressive strength of the CO3Ap scaffold was 0.7MPa. Based on the compressive strength and carbonate content results, NaHCO3 aqueous solutions were chosen as carbonate sources for phase transformation to fabricate a CO3Ap scaffold over 6 days.

Evaluation of 5% Na2O-Incorporated Calcium Metaphosphate as a Scaffold for Tissue-Engineered Bone Regeneration

2006 ◽  
Vol 309-311 ◽  
pp. 985-988 ◽  
Author(s):  
J.H. Yoon ◽  
J.T. Kim ◽  
Eui Kyun Park ◽  
Shin Yoon Kim ◽  
Chang Kuk You ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Bone Regeneration ◽  
Average Pore Size ◽  
Ectopic Bone Formation ◽  
Cellular Reaction ◽  
Average Pore ◽  
Cellular Attachment ◽  
Ectopic Bone ◽  
Osteogenic Effect

As a part of the effort to develop a suitable scaffold for tissue-engineered bone regeneration, we modified calcium metaphosphate (CMP) ceramic with Na20 and evaluated its efficiency as a scaffold. We incorporate 5% Na20 into pure CMP and prepare for an average pore size of 250 or 450 µm average pore sizes. The incorporation of 5% Na2O caused reduced compressive strength and there was no change in biodegradability. The in vitro cellular attachment and proliferation rate, however, were slightly improved. The 5% Na2O-incorporated macroporous CMP ceramic-cell constructs treated with Emdogain induced ectopic bone formation more effectively than those without Emdogain treatment. These results suggest that the incorporation of 5% Na2O into pure CMP is not effective for improving the physical characteristics of pure CMP but it is positive for improving the cellular reaction and osteogenic effect with the addition of Emdogain.

Fabrication of macroporous carbonate apatite foam by hydrothermal conversion of α-tricalcium phosphate in carbonate solutions

2008 ◽  
Vol 87A (4) ◽  
pp. 957-963 ◽  
Author(s):  
H. Wakae ◽  
A. Takeuchi ◽  
K. Udoh ◽  
S. Matsuya ◽  
M. L. Munar ◽  
...  
Keyword(s):  
Tricalcium Phosphate ◽  
Carbonate Apatite ◽  
Hydrothermal Conversion ◽  
Carbonate Solutions

scholarly journals Tailoring the strength and porosity of rapid-hardening magnesia phosphate paste via the pre-foaming method

2015 ◽  
Vol 5 (1) ◽  
Author(s):  
Li-Jie Liu ◽  
Jin-Hong Li ◽  
Xiang Wang ◽  
Ting-Ting Qian ◽  
Xiao-Hui Li
Keyword(s):  
Compressive Strength ◽  
Porous Structure ◽  
Bulk Density ◽  
Sodium Silicate ◽  
Average Pore Size ◽  
Hydration Product ◽  
Polypropylene Fibers ◽  
High Porosity ◽  
Average Pore ◽  
Maximum Compressive Strength

Abstract High-porosity magnesia phosphate paste (HPMPP) was prepared via the pre-foaming method. In the pre-foaming method, sintering treatment was not required. The bulk density and maximum compressive strength of the HPMPP prepared according to the ratio of water to solids (W/So) of 0.32 reached 464.00 ± 5.00 Kg/m3 and 0.30 ± 0.05 MPa, respectively. The compressive strength increased with the increases in the addition amounts of sodium silicate and polypropylene fibers. The bulk density of HPMPP increased with the increase in the addition of sodium silicate and decreased with the increase in the addition of polypropylene fibers. Besides, the porosity of the magnesia phosphate paste increased from 79.85% to 81.27% and from 80.31% to 83.75% after the addition of sodium silicate and polypropylene fibers respectively. The highest porosity (83.75%) of the prepared HPMPP was realized under the addition proportion (sodium silicate: polypropylene fibers: solids = 0.06:0.0025:1). The average pore size of the prepared HPMPP is about 180 μm and the pore distribution range is relatively narrow. The hydration product (struvite) is combined with MgO particle one by one and then coated on the surface of bubbles. With the decrease of the water content, after breaking bubbles, the porous structure can be achieved.

Preparation and Research of Porous KGM/ Collagen II Composite Cartilage Scaffolds

2013 ◽  
Vol 774-776 ◽  
pp. 949-953
Author(s):  
Ming Hua Huang ◽  
Hui Dong ◽  
Di Ru Xu ◽  
Duan Cheng Wang ◽  
Yong Shun Cui ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Water Absorption ◽  
Pore Size ◽  
Raw Materials ◽  
Average Pore Size ◽  
Crosslinking Agent ◽  
Three Dimensional ◽  
Average Pore ◽  
Blending Method ◽  
Collagen Ii

KGM and Collagen II were selected as the main raw materials and ammonia served as the crosslinking agent to prepare the porous KGM / COLII composite cartilage scaffolds by blending method and freeze-drying method. The porosity, average pore size, compressive strength and water absorption were measured on the basis of the related standard. The scaffolds were characterized by SEM and XRD. The results show that the optimal program of preparing composite cartilage scaffolds is KGM (2g), COLII (1g), freeze temperature (-20 ° C) and ammonia (0.1 ml). The optimal cartilage scaffolds are porous three-dimensional network structures which the porosity is more than 90%; the average pore size is about 200μm; the compressive strength is about 0.75Mpa and the water absorption reaches up to 892%.

Response Surface Methodology Study on Macroporous Hydroxyapatite Prepared by Protein Foaming-Consolidation Method

2020 ◽  
Vol 1000 ◽  
pp. 132-138
Author(s):  
Ahmad Fadli ◽  
Feblil Huda ◽  
Komalasari ◽  
Ilham Habib ◽  
Arosyidin
Keyword(s):  
Compressive Strength ◽  
Response Surface Methodology ◽  
Pore Size ◽  
Response Surface ◽  
Biomedical Application ◽  
Average Pore Size ◽  
P Value ◽  
Mixing Rate ◽  
Average Pore ◽  
Porous Hydroxyapatite

Macroporous hydroxyapatite have been used in biomedical application especially for bone graft. The objective of this research was to study the effect of yolk addition, rate of sintering temperature rise, and rate of stirring on the physical, chemical and mechanical properties of porous hydroxyapatite prepared using protein foaming-starch consolidation method. The slurry was made by mixing the hydroxyapatite and starch powder with Darvan 821A and yolk in a beaker glass. The slurry was stirred mechanically at rate of 150 rpm for 3 hours and it poured in cylindrical mold. Subsequently the slurry was heated in air oven at 180°C for 1 hour. The dried green bodies were burn out at 600°C ended by sintering at 1250°C. The porous hydroxyapatite with average pore size in the range of 13.7-17.9 μm, porosity of 59.3-63.6 % and compressive strength of 5.17-8.2 MPa was obtained. The calculation result of response surface methodology shows that p-value < 0.05 and lack of fit > 0.05. The most effecting factor significantly was hydroxyapatite addition that followed by mixing rate and temperature rising rate of sintering. Optimum condition hydroxyapatite addition of 22 gr, mixing rate of 150 rpm and temperature rising rate of sintering of 2.8°C/minutes with the optimum value of response for pore size by 17.665 μm, porosity by 63.475% and compressive strength 5.17 MPa.

scholarly journals Preparation of Porous Materials by Magnesium Phosphate Cement with High Permeability

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Lai Zhenyu ◽  
Hu Yang ◽  
Fu Xiaojie ◽  
Lu Zhongyuan ◽  
Lv Shuzhen
Keyword(s):  
Compressive Strength ◽  
Pore Size ◽  
Average Pore Size ◽  
Zinc Powder ◽  
Magnesium Phosphate ◽  
High Permeability ◽  
Average Pore ◽  
Foaming Agent ◽  
Powder Content ◽  
Chemical Foaming

High permeability and strength magnesium phosphate cement (MPC) with porosity, average pore size, and compressive strength varied from 63.2% to 74%, 138.7 μm to 284.7 μm and 2.3 MPa to 4.7 MPa, respectively, were successfully prepared by combining the physical foaming method and chemically entrained gas method at room temperature. The effects of borax content, chemical foaming agent content, zinc powder content and W/S ratio on the porosity, pore size distribution, compressive strength, and permeability of the MPC were investigated. The results indicate that the chemical foaming agent content tends to have little impact on the porosity and compressive strength, and the zinc powder content has the most significant influence on the average pore size of MPC. The air pores distribution and connectivity of MPC were mainly controlled by the borax content, W/S ratio, and chemical foaming agent content. Zinc powder played a destructive role in the pores formed by the early physical foaming and led to an increase in pore size and a large number of through pores, which increased the permeability of the materials.

Preparation and Properties of Porous β–Tricalcium Phosphate Bone Graft

2012 ◽  
Vol 624 ◽  
pp. 226-230 ◽  
Author(s):  
Li Sheng Zhao ◽  
Zheng Wang ◽  
Ke Ya Mao ◽  
Bin Deng ◽  
Yuan Fu Yi ◽  
...  
Keyword(s):  
Compressive Strength ◽  
Porous Structure ◽  
Bone Graft ◽  
Cancellous Bone ◽  
Tricalcium Phosphate ◽  
Bone Repair ◽  
X Ray Diffraction ◽  
X Ray ◽  
Beta Tricalcium Phosphate ◽  
Similar Chemical

The need for bone repair has increased as the population ages. However, currently, the bone grafts still have some disadvantages, such as low compressive strength and porosity, which limit their use. In order to solve these disadvantages, in this study, the porous beta-tricalcium phosphate (β-TCP) anorganic bone graft were prepared from healthy bovine cancellous bone by cell-free, defat and twice calcinations. X-ray diffraction (XRD) was used to investigate the chemical composition of the bone graft. And the morphology, porosity and mechanical strength of the bone graft were also evaluated. The results showed that most constituent of the bone graft was β-TCP. In addition, the bone graft scaffold exhibited the macro and micro porous structure and the porosity was 57.63%, just as the nature cancellous bone. The compressive strength was 4.47±0.63MPa. Above all, the porous β-TCP anorganic bone graft not only has similar chemical composites as the nature cancellous bone, but also it can effectively retain the porous structure of natural cancellous bone and provides optimal channels for the ingrowth of new bone and blood vessels.Therefore, the porous β-TCP anorganic bone graft is a potential biomaterial in bone tissue engineering.

scholarly journals Comparison of Carbonate Apatite and .BETA.-tricalcium Phosphate (Resorbable Calcium Phosphates) Implanted Subcutaneously into the Back of Rats

2006 ◽  
Vol 25 (2) ◽  
pp. 219-225 ◽  
Author(s):  
Motohiko NAGAYAMA ◽  
Hiroshi TAKEUCHI ◽  
Yutaka DOI
Keyword(s):  
Tricalcium Phosphate ◽  
Calcium Phosphates ◽  
Carbonate Apatite ◽  
Beta Tricalcium Phosphate

scholarly journals Effect of microsilica content on microstructure and properties of foamed ceramics with needle-like mullite

2019 ◽  
Vol 13 (2) ◽  
pp. 202-209 ◽  
Author(s):  
Wenying Zhou ◽  
Wen Yan ◽  
Nan Li ◽  
Yuanbing Li ◽  
Yajie Dai ◽  
...  
Keyword(s):  
Thermal Conductivity ◽  
Compressive Strength ◽  
Raw Materials ◽  
Average Pore Size ◽  
High Porosity ◽  
Sintering Process ◽  
Average Pore ◽  
Linear Change ◽  
Direct Foaming Method ◽  
Industrial Alumina

In this study, five foamed ceramics with struts containing needle-like mullite were prepared by direct-foaming method using white clay, industrial alumina and microsilica powder as raw materials. The effects of microsilica content on the phase compositions, microstructures and properties of foamed ceramics were investigated. The results showed that the adding of microsilica decreased the average pore size and apparent porosity and increased the compressive strength and thermal conductivity of the foamed ceramics by affecting the properties of foamed slurry and reaction sintering process. The foamed ceramics with 10 wt.% microsilica content showed the best properties with high porosity of 75.8%, positive reheating linear change, compressive strength of 1.44MPa and low thermal conductivity of 0.219W/(m?K) (at 350?C).

scholarly journals Quality Assessment of SCGPC using Ultra-Sonic Pulse Velocity at High Temperature

2019 ◽  
Vol 8 (12) ◽  
pp. 810-815
Keyword(s):  
Compressive Strength ◽  
High Temperature ◽  
Pore Size ◽  
Average Pore Size ◽  
Pulse Velocity ◽  
Moisture Loss ◽  
Geopolymer Concrete ◽  
Lower Strength ◽  
Average Pore ◽  
Significant Decrement

This paper presents the effect of high temperature on compressive strength and ultra-sonic pulse velocity of self compacting geopolymer concrete (SCGPC) mixes with varying molarities viz., 8M, 10M and 12M. At different ages, the specimens were kept at a high temperature (100, 200, 400, 600 and 800oC) for 2 hours and then testing of the specimens was carried out. Prior to compressive strength of test specimens, ultra-sonic pulse velocity (UPV) test was performed after 7, 28 and 56 days of curing. From the results, it is revealed that the compressive strength and UPV results of SCGPC were decreased with the increase in temperature from 1000C to 8000C in all curing periods. Finally, it is concluded that the significant decrement in compressive strength and UPV up to 8000C is mainly due to continuous moisture loss from the specimens and increase in the average pore size, which produce the lower strength and pulse velocity of the concrete.

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