Malakoplakia mimics urinary bladder cancer: A case report

Introduction. Malakoplakia is an unusual and very rare chronic inflammatory disease. In bladder especially it can mimic malignancy and lead to serious misdiagnosis. Case report. We presented a case of a middle-aged woman with persistent macrohematuria and cystoscopically polypoid bladder mass that resembled a neoplastic process. The final diagnosis was based on cystoscopic biopsy and microscopic findings of acidophilic, foamy histiocytes with the presence of Michaelis-Gutmann inclusions which are characteristic for diagnosis of malakoplakia. Immunohistochemistry confirmed diagnosis by demonstrating CD68-positive macrophages. Conclusion. Urinary bladder malakoplakia should be considered in patients with persistent urinary tract infections and tumor mass at cystoscopy. Early identification with prompt antibiotic treatment can be helpful in avoiding unnecessary surgical interventions and in preventing development of possible complications.

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Isolated Gastric Myeloid Sarcoma: A Case Report and Review of the Literature

Case Reports in Hematology ◽

10.1155/2014/541807 ◽

2014 ◽

Vol 2014 ◽

pp. 1-4 ◽

Cited By ~ 3

Author(s):

Pankit Vachhani ◽

Prithviraj Bose

Keyword(s):

Bone Marrow ◽

Acute Myeloid Leukemia ◽

Case Report ◽

Myeloid Leukemia ◽

Bone Marrow Involvement ◽

Myeloid Sarcoma ◽

Review Of The Literature ◽

Aged Woman ◽

Middle Aged Woman ◽

Acute Myeloid

Myeloid sarcoma represents the proliferation of myeloblasts of acute myeloid leukemia (AML) at extramedullary sites. While extramedullary involvement in AML is uncommon in itself, isolated myeloid sarcomas, that is, myeloid sarcomas without any bone marrow involvement, are extremely rare and pose a diagnostic and therapeutic challenge. Here, we present the case of a middle-aged woman with isolated myeloid sarcoma in the stomach—an organ seldom involved by this disease. Additionally, the literature on the epidemiology, diagnosis, pathology, prognosis, and therapeutic options in myeloid sarcomas has been reviewed.

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Micturition-triggered severe headache associated with bladder paraganglioma: A case report

Cephalalgia ◽

10.1177/03331024211036155 ◽

2021 ◽

pp. 033310242110361

Author(s):

Yonghui Liu ◽

Tianlu Wei

Keyword(s):

Case Report ◽

Neuroendocrine Tumors ◽

Pain Syndrome ◽

Signs And Symptoms ◽

Headache Disorder ◽

Severe Headache ◽

Case Description ◽

Middle Aged ◽

Aged Woman ◽

Middle Aged Woman

Background Paragangliomas are rare neuroendocrine tumors, especially in the bladder. Although many paragangliomas are non-functional, functioning paragangliomas present with many non-specific signs and symptoms, such as hypertension and headache, complicating their diagnosis. Here, we report a case of micturition-induced severe headache associated with a bladder paraganglioma. Case description: This report describes a severe headache disorder triggered by micturition and associated with a bladder paraganglioma in a middle-aged woman. Her pain occurred consistently after micturition, beginning from the left side of the nose and gradually extended to the forehead and the parietal and occipital regions. The headaches lasted 5–10 min. Removal of the paraganglioma completely eliminated the patient’s pain syndrome. Conclusion This case elucidates the association between micturition-triggered headaches and bladder paragangliomas. The presence of a post-micturition severe headache should suggest the possibility of a bladder paraganglioma.

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270 A Case Report on a Primary Hepatic Yolk Sac Tumor in a Middle-Aged Woman—A Challenging Diagnosis

American Journal of Clinical Pathology ◽

10.1093/ajcp/aqx123.269 ◽

2018 ◽

Vol 149 (suppl_1) ◽

pp. S115-S115

Author(s):

Andrey Prilutskiy ◽

Josenia Tan ◽

Qing Zhao

Keyword(s):

Case Report ◽

Yolk Sac ◽

Yolk Sac Tumor ◽

Middle Aged ◽

Aged Woman ◽

Middle Aged Woman

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Somatically derived Yolk Sac tumor of the urinary bladder: A case report and differential diagnosis

10.21203/rs.2.24486/v1 ◽

2020 ◽

Author(s):

Nadia Espejo-Herrera ◽

Enric Condom Mundó

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Urinary Bladder ◽

Urothelial Carcinoma ◽

Final Diagnosis ◽

Yolk Sac ◽

Yolk Sac Tumor ◽

High Grade ◽

Yolk Sac Tumors ◽

Urinary Bladder Tumor

Abstract Background: Yolk sac tumor is a germ cell neoplasm that arises predominantly in the gonads, but can also derive from somatic neoplasms in extragonadal locations. These cases have been denominated recently as “somatically derived Yolk sac tumors”, and have been documented in several locations, although reports from the urinary tract are scarce. To our knowledge, this is the first report of a Yolk sac tumor derived from urothelial carcinoma. Case presentation: We present a unique case of a 76-year-old man with a recurrent urinary bladder tumor, initially interpreted as a high grade urothelial carcinoma with glandular differentiation. In the recurrent tumor, diverse histological patterns were identified, including glandular, hepatoid and sarcomatoid. This tumor showed positivity for AFP, GLP3 and SALL4, and negativity for CK7 and EMA. Fluorescent in situ hybridization study showed a polysomic pattern of chromosome 12. All these findings led to the final diagnosis of a Yolk sac tumor derived from urothelial carcinoma. Conclusions: Somatically derived Yolk Sac tumors should be considered in the differential diagnosis of a high grade urothelial carcinoma, particularly when glandular and other unusual patterns are observed. Key words: Yolk sac tumor, somatically derived, urothelial carcinoma, urinary bladder, case report.

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Herbal supplement (Combi-5) in the management of COVID 19 individual with mild to moderate symptoms: a case report

Journal of Complementary and Integrative Medicine ◽

10.1515/jcim-2020-0430 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Augustine Anayochukwu Onyeaghala ◽

Emmanuella Ogechi Onyeaghala ◽

Chinedum Peace Babalola ◽

Oluwasanmi Olayinka Aina ◽

Dadik Jelpe

Keyword(s):

Case Report ◽

Controlled Trial ◽

Herbal Supplement ◽

Early Recovery ◽

Case Presentation ◽

Aged Woman ◽

Clinical Benefits ◽

Middle Aged Woman ◽

Zinc Supplements ◽

Short Time

Abstract Objective To explore repurposing known natural products for managing patients with mild to moderate symptoms of COVID-19. Case presentation We present a case report of a middle aged woman, who was positive to COVID 19, with mild to moderate symptoms; who self –managed at home using well formulated herbal supplement (Combi-5) taken along with vitamin C and Zinc supplements. She recovered within a short time. Conclusions While we may not conclude from this report that Combi-5 was solely responsible for the recovery of the patient, we strongly believe that it played significant role through different mechanisms in facilitating early recovery from the infection. Further studies are needed to evaluate the phytochemical and pharmacological constituents of the supplement; investigate its direct effect(s) on SARS CoV-2 and conduct randomized controlled trial to elucidate its clinical benefits.

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