Dizziness

2016 ◽  
Author(s):  
Joshua N. Goldstein

Dizziness is a relatively common condition in the emergency setting. Patient descriptions of their symptoms can be vague and inconsistent. This review highlights the most important aspects of the history and physical examination that can help differentiate among different causes of dizziness. In addition, it covers the pathophysiology of inner ear disease, including diagrams of vestibular anatomy. For the history, it is critical to capture dizziness, duration, triggers for dizziness, and associated symptoms. For the physical examination, a focused neurologic assessment is important, including balance, coordination, as well as an oculomotor assessment. For treatment of benign positional vertigo, various canalith repositioning maneuvers are described and diagrams shown. For vestibular neuritis, treatment options including vestibular rehabilitation and steroids are discussed. Finally, medical options for symptomatic therapy are listed.  Key words: Dizziness, benign positional vertigo, canalith repositioning maneuver, vestibular disorders. This review contains 7 highly rendered figures, 7 tables, and 40 references.


2019 ◽  
Vol 39 (01) ◽  
pp. 027-040 ◽  
Author(s):  
Jonathan Edlow ◽  
Kiersten Gurley

AbstractDizziness is a common chief complaint with an extensive differential diagnosis that includes both benign and serious conditions. Physicians must distinguish the majority of patients who suffer from self-limiting conditions from those with serious illnesses that require acute treatment. The preferred approach to the diagnosis of an acutely dizzy patient emphasizes different aspects of the history to guide a focused physical examination, with the goal of differentiating benign peripheral vestibular conditions from dangerous posterior circulation strokes. Currently, misdiagnoses are frequent and diagnostic testing costs are high. This partly relates to use of an outdated diagnostic paradigm. This commonly used traditional approach relies on dizziness “symptom quality” or “type” (vertigo, presyncope, disequilibrium) to guide inquiry. It does not distinguish benign from dangerous causes and is inconsistent with current best evidence. A better approach categorizes patients into three groups based on timing and triggers. Each category has its own differential diagnosis and targeted bedside approach: (1) acute vestibular syndrome, where bedside physical examination differentiates vestibular neuritis from stroke; (2) spontaneous episodic vestibular syndrome, where associated symptoms help differentiate vestibular migraine from transient ischemic attack; and (3) triggered episodic vestibular syndrome, where the Dix-Hallpike and supine roll test help differentiate benign paroxysmal positional vertigo from posterior fossa structural lesions. The “timing and triggers” diagnostic approach for the acutely dizzy derives from current best evidence and offers the potential to reduce misdiagnosis while simultaneously decreasing diagnostic test overuse, unnecessary hospitalization, and incorrect treatments.



2021 ◽  
pp. 000348942110254
Author(s):  
Eric J. Formeister ◽  
Ricky Chae ◽  
Emily Wong ◽  
Whitney Chiao ◽  
Lauren Pasquesi ◽  
...  

Objectives: To elucidate differences in demographic and clinical characteristics between patients with episodic and chronic dizziness. Methods: A cross-sectional, observational study of 217 adults referred for dizziness at 1 tertiary center was undertaken. Subjects were split into a chronic dizziness group (>15 dizzy days per month) and an episodic dizziness group (<15 dizzy days per month). Results: 217 adults (average age, 53.7 years; 56.7% female) participated. One-third (n = 74) met criteria for chronic dizziness. Dizziness handicap inventory (DHI) scores were significantly higher in those with chronic dizziness compared to those with episodic dizziness (53.9 vs 40.7; P < .001). Comorbid depression and anxiety were more prevalent in those with chronic dizziness (44.6% and 47.3% vs 37.8% and 35.7%, respectively; P > .05). Abnormal vestibular testing and abnormal imaging studies did not differ significantly between the 2 groups. Ménière’s disease and BPPV were significantly more common among those with episodic dizziness, while the prevalence of vestibular migraine did not differ according to chronicity of symptoms. A multivariate regression that included age, sex, DHI, history of anxiety and/or depression, associated symptoms, and dizziness triggers was able to account for 15% of the variance in the chronicity of dizziness (pseudo- R2 = 0.15; P < .001). Conclusions: Those who suffer from chronic dizziness have significantly higher DHI and high comorbid rates of depression and anxiety than those with episodic dizziness. Our findings show that factors other than diagnosis alone are important in the chronification of dizziness, an observation that could help improve on multimodal treatment options for this group of patients.



Hematology ◽  
2011 ◽  
Vol 2011 (1) ◽  
pp. 128-135 ◽  
Author(s):  
Andreas Hochhaus

Abstract Elucidation of the pathogenesis of chronic myeloid leukemia (CML) and the introduction of tyrosine kinase inhibitors (TKIs) has transformed this disease from being invariably fatal to being the type of leukemia with the best prognosis. Median survival associated with CML is estimated at > 20 years. Nevertheless, blast crisis occurs at an incidence of 1%-2% per year, and once this has occurred, treatment options are limited and survival is short. Due to the overall therapeutic success, the prevalence of CML is gradually increasing. The optimal management of this disease includes access to modern therapies and standardized surveillance methods for all patients, which will certainly create challenges. Furthermore, all available TKIs show mild but frequent side effects that may require symptomatic therapy. Adherence to therapy is the key prerequisite for efficacy of the drugs and for long-term success. Comprehensive information on the nature of the disease and the need for the continuous treatment using the appropriate dosages and timely information on efficacy data are key factors for optimal compliance. Standardized laboratory methods are required to provide optimal surveillance according to current recommendations. CML occurs in all age groups. Despite a median age of 55-60 years, particular challenges are the management of the disease in children, young women with the wish to get pregnant, and older patients. The main challenges in the long-term management of CML patients are discussed in this review.



2000 ◽  
Vol 114 (11) ◽  
pp. 844-847 ◽  
Author(s):  
Najam-Ul-Hasnain Khan F.C.P.S. ◽  
Mohammad Mujeeb

Benign paroxysmal positional vertigo (BPPV) is one of the commonest causes of peripheral vestibular disorders. In this prospective study 21 patients with BPPV were treated by Epley’s manoeuvre. All patients had an immediate improvement in their symptoms. Recurrence was noted in three patients who required further treatment sessions with resultant improvement in all. However, one patient who originally had suffered from Me´nie`re’s disease involving the same ear for more than 14 years developed another recurrence which was treated successfully by further application of Epley’s manoeuvre. This study supports the usefulness of Epley’s manoeuvre for the treatment of BPPV.



2000 ◽  
Vol 257 (3) ◽  
pp. 133-136 ◽  
Author(s):  
T. Dal ◽  
L. N. Özlüoğlu ◽  
N. T. Ergin


2019 ◽  
Vol 90 (e7) ◽  
pp. A8.2-A8
Author(s):  
Allison S Young ◽  
Corinna Lechner ◽  
Andrew P Bradshaw ◽  
Hamish G MacDougall ◽  
Deborah A Black ◽  
...  

IntroductionThe diagnosis of vestibular disorders may be facilitated by analysing patient-initiated capture of ictal nystagmus.MethodsAdults with a history of recurrent vertigo were taught to self-record spontaneous and positional-nystagmus at home while symptomatic, using video-goggles. Patients with final diagnoses of disorders presenting with recurrent vertigo were analysed: 121 patients with Ménière’s Disease (MD), Vestibular Migraine (VM), Benign Positional Vertigo (BPV), Episodic Ataxia Type II (EAII), Vestibular Paroxysmia (VP) or Superior Semicircular Canal Dehiscence (SSCD) were included.ResultsOf 43 MD patients, 40 showed high-velocity spontaneous horizontal-nystagmus (median slow-phase velocity (SPV) 39.7 degrees/second (°/s); Twenty-one showed horizontal-nystagmus reversing direction within 12-hours (24 on separate days). In 44 of 67 patients with VM, low velocity spontaneous horizontal (n=28, 4.9°/s), up-beating (n=6, 15.5°/s) or down-beating-nystagmus (n=10, 5.1°/s) was observed; Sixteen showed positional-nystagmus only, and seven had no nystagmus. Spontaneous horizontal-nystagmus with SPV >12.05°/s had a sensitivity and specificity of 95.3% and 82.1% for MD. Nystagmus direction-change within 12-hours was highly specific (95.7%) for MD. Spontaneous vertical-nystagmus was highly specific (93.0%) for VM. In the seven BPV patients, spontaneous-nystagmus was absent or <3°/s, and characteristic paroxysmal positional nystagmus was observed in all cases. Patients with central and MD-related positional vertigo demonstrated persistent nystagmus. Two patients with EAII showed spontaneous vertical nystagmus, one patient with VP showed short bursts of horizontal-torsional nystagmus lasting 5–10s, and one patient with SSCD demonstrated paroxysmal torsional down-beating nystagmus when supine.ConclusionsPatient-initiated vestibular event-monitoring is feasible and could facilitate rapid and accurate diagnosis of episodic vestibular disorders.



2017 ◽  
Vol 5 (4_suppl4) ◽  
pp. 2325967117S0013
Author(s):  
Hagen Hommel

Aims and Objectives: Baker’s cysts are common in knees with degenerative changes. Common opinion is that most them vanish after treatment of the intraarticular knee disorder. The present study aimed to evaluate the fate of Baker’s cyst and its associated symptoms after TKA. Materials and Methods: In this prospective study, 105 patients with a MRI verified Baker’s cyst, primary OA and an appointment for TKA were included. Three patients were lost to follow-up (two died and one septic TKA removal). Mean age was 70.1 ± 7 years. Ultrasound was performed to evaluate the existing and the gross size of the cyst was performed before and one year (mean 12.3 ± 1.1 months) after TKA. Additionally, Baker’s cyst associated symptoms were recorded Results: After one year, Baker’s cysts were still detected in 85.3% of the patients (n = 87). There was a significant reduction in Baker’s cyst associated symptoms from before (70.6%) to after surgery (31.4%; p < 0.0001). No patients developed new Baker’s cyst associated symptoms. However, out of the 72 patients that reported preoperatively about Baker’s cyst associated symptoms, one year after surgery 44.4% (n = 32) of the patients still complained about Baker’s cyst associated symptoms. The size of Baker’s cysts decreased significantly from pre- (mean 1447 mm2) to postoperative (969 mm2) ultrasound assessment (p < 0.0001). Conclusion: Baker’s cysts vanished only in a small amount of patients (15%) one year after TKA. Nevertheless in this in general considered successful surgery, in close to half of the patients (44.4%) with preoperative Baker’s cyst associated symptoms, these symptoms did not vanish until one year after TKA. Thus, it might be worthwhile to evaluate its treatment options and include them in future treatment plans.



1994 ◽  
Vol 110 (4) ◽  
pp. 391-396 ◽  
Author(s):  
Brian W. Blakley

The efficacy of the canalith repositioning maneuver in the treatment of benign positional vertigo was assessed in this controlled, randomized trial of 38 subjects. Treated subjects underwent the maneuver and control subjects did not. All were reevaluated 1 month after treatment. The number of persons experiencing subjective improvement was not statistically significantly different between the treatment and control groups. All patients, in both experimental and control groups, in this study experienced substantial improvement. Although the maneuver is safe it does not have treatment benefit for benign positional vertigo.



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