scholarly journals Expression of LIF and LIFR in periodontal tissue during orthodontic tooth movement

2011 ◽  
Vol 81 (4) ◽  
pp. 600-608 ◽  
Author(s):  
Youde Liang ◽  
Yi Zhou ◽  
Tao Jiang ◽  
Zhen Zhang ◽  
Su Wang ◽  
...  
Keyword(s):  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Periodontal Tissue

E22 Stress analysis of tooth and periodontal tissue during orthodontic tooth movement

2011 ◽  
Vol 2011 (0) ◽  
pp. 149-150
Author(s):  
Yousuke KAWAI ◽  
Yasukazu NISHI ◽  
Mamoru MURATA ◽  
Akira NAKAJIMA ◽  
Kazuyoshi HOSHINO ◽  
...  
Keyword(s):  
Stress Analysis ◽  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Periodontal Tissue

scholarly journals Dynamics of Alloplastic Bone Grafts on an Early Stage of Corticotomy-Facilitated Orthodontic Tooth Movement in Beagle Dogs

2014 ◽  
Vol 2014 ◽  
pp. 1-13
Author(s):  
Hyung-Joo Choi ◽  
Dong-Yeol Lee ◽  
Tae-Woo Kim
Keyword(s):  
Orthodontic Treatment ◽  
Tooth Movement ◽  
Early Stage ◽  
Orthodontic Tooth Movement ◽  
Bone Grafts ◽  
Periodontal Tissue ◽  
Histological Findings ◽  
Beagle Dogs ◽  
The Stability ◽  
Short Time

Alveolar augmented corticotomy is effective in accelerating orthodontic tooth movement, but the effect only lasts for a relatively short time. Therefore, the purpose of this study was to investigate the underlying biology of the immediate periodontal response to orthodontic tooth movement after a corticotomy with alloplastic bone grafts. The results demonstrated that measurable tooth movement began as early as 3 days after the intervention in beagle dogs. Based on the results and histological findings, augmented corticotomy-facilitated orthodontic tooth movement might enhance the condition of the periodontal tissue and the stability of the outcomes of orthodontic treatment.

scholarly journals Biomechanical Interfaces of Corticotomies on Periodontal Tissue Remodeling during Orthodontic Tooth Movement

Coatings ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 1
Author(s):  
Ruojing Liu ◽  
Li Huang ◽  
Xiaoyue Xiao ◽  
Yuzhe Guan ◽  
Yukun Jiang ◽  
...  
Keyword(s):  
Alveolar Bone ◽  
Tooth Movement ◽  
Root Resorption ◽  
Orthodontic Tooth Movement ◽  
Tissue Remodeling ◽  
Sham Operation ◽  
Periodontal Tissue ◽  
Wnt Signal Pathway ◽  
Post Surgery ◽  
Periodontal Tissue Remodeling

Corticotomy is an effective approach in accelerating orthodontic tooth movement (OTM) in clinical treatment. Corticotomy causes regional acceleratory phenomenon (RAP) in the alveolar bone of surgical sites. However, the molecular mechanism of RAP after corticotomy remains unclear. Herein, we established a mouse model to study the biomechanical interfaces of corticotomy-assisted OTM and to investigate the histological responses and underlying cellular mechanism. A total of 144 male C57BL/6 mice were randomly assigned into four groups: corticotomy alone (Corti), sham operation (Sham), corticotomy with tooth movement (Corti + TM), and sham operation with tooth movement (Sham + TM). Nickel–titanium orthodontic springs were applied to trigger tooth movement. Mice were sacrificed on Post-Surgery Day (PSD) 3, 7, 14, 21, and 28 for radiographic, histological, immunohistochemical, and molecular biological analyses. The results reveal that corticotomy significantly promoted alveolar bone turnover and periodontal tissue remodeling. During orthodontic tooth movement, corticotomy significantly promoted osteogenic and proliferative activity, accelerated tooth movement, and eliminated root resorption by upregulating Wnt signal pathway.

scholarly journals Immunolocalization of FGF-2 and VEGF in rat periodontal ligament during experimental tooth movement

2014 ◽  
Vol 19 (3) ◽  
pp. 67-74 ◽  
Author(s):  
Milene Freitas Lima Salomão ◽  
Sílvia Regina de Almeida Reis ◽  
Vera Lúcia Costa Vale ◽  
Cintia de Vasconcellos Machado ◽  
Roberto Meyer ◽  
...  
Keyword(s):  
Growth Factor ◽  
Periodontal Ligament ◽  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Periodontal Tissue ◽  
Group Iii ◽  
Group I ◽  
Male Wistar Rats ◽  
Experimental Side ◽  
Orthodontic Forces

OBJECTIVE: This article aimed at identifying the expression of fibroblast growth factor-2 (FGF-2) and vascular endothelial growth factor (VEGF) in the tension and pressure areas of rat periodontal ligament, in different periods of experimental orthodontic tooth movement. METHODS: An orthodontic force of 0.5 N was applied to the upper right first molar of 18 male Wistar rats for periods of 3 (group I), 7 (group II) and 14 days (group III). The counter-side first molar was used as a control. The animals were euthanized at the aforementioned time periods, and their maxillary bone was removed and fixed. After demineralization, the specimens were histologically processed and embedded in paraffin. FGF-2 and VEGF expressions were studied through immunohistochemistry and morphological analysis. RESULTS: The experimental side showed a higher expression of both FGF-2 and VEGF in all groups, when compared with the control side (P < 0.05). Statistically significant differences were also found between the tension and pressure areas in the experimental side. CONCLUSION: Both FGF-2 and VEGF are expressed in rat periodontal tissue. Additionally, these growth factors are upregulated when orthodontic forces are applied, thereby suggesting that they play an important role in changes that occur in periodontal tissue during orthodontic movement.

scholarly journals Localization of osteopontin and osterix in periodontal tissue during orthodontic tooth movement in rats

2011 ◽  
Vol 82 (1) ◽  
pp. 107-114 ◽  
Author(s):  
Ji-Youn Kim ◽  
Byung-In Kim ◽  
Seong-Suk Jue ◽  
Jae Hyun Park ◽  
Je-Won Shin
Keyword(s):  
Alveolar Bone ◽  
Tooth Movement ◽  
Orthodontic Tooth Movement ◽  
Nickel Titanium ◽  
Nuclear Antigen ◽  
Periodontal Tissue ◽  
Histological Changes ◽  
Proliferating Cell ◽  
Periodontal Tissue Remodeling

Abstract Objective: To evaluate the localization of osteopontin (OPN) and osterix in periodontal tissue during experimental tooth movement with heavy force in rats. Materials and Methods: Nickel-titanium closed-coil springs were used to create a 100 g mesial force to the maxillary first molars. On days 3, 7, 10, and 14 after force application, histological changes in periodontium were examined by immunohistochemistry using proliferating cell nuclear antigen (PCNA), OPN, and osterix. Results: PCNA-positive cells were found close to the alveolar bone and cementum on both sides. OPN-positive cells were observed along the cementing line of the cementum and bone on both sides and also were visible along with newly formed fibers in the periodontal ligament on the tension side. Osterix-positive cells were strongly detected on the surface of the alveolar bone and cementum on both sides. Conclusions: During tooth movement, periodontal remodeling occurs on both sides. These results indicate that OPN and osterix may play an important role of differentiation and osteoblasts and cementoblasts matrix formation during periodontal tissue remodeling.

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