scholarly journals Localization of Ebk/MDK1 in Mouse Oral Development

2003 ◽  
Vol 45 (2) ◽  
pp. 52-58
Author(s):  
Takehiko Shimizu ◽  
Takahide Maeda
Keyword(s):  
1988 ◽  
Vol 90 (2) ◽  
pp. 287-293
Author(s):  
M. F. CHAU ◽  
STEPHEN F. NG

The present study further analyses the importance of postmeiotic divisional derivatives of the micronucleus in the development of the oral apparatus of Paramecium during sexual reproduction. Cell lines possessing defective micronuclei generated by laser microbeam irradiation of the micronucleus were employed. They exhibited anomalies in nuclear reorganization and stomatogenesis in the sexual cycle. During autogamy, in some cells the micronuclear cycle terminated shortly after meiosis, resulting in the loss of all postmeiotic micronuclear derivatives. Stomatogenesis became arrested at an early stage of assembly of the oral membranelles, but the old oral apparatus was resorbed as usual, leading to the production of astomatous cells at the end of the sexual cycle. Conjugation of these cell lines with normal micronucleates rescued both nucleogenesis and stomatogenesis in the defective micronucleate conjugant, primarily as a result of transfer of the male gametic nucleus from the normal conjugant to the defective-micronucleate mate. These observations demonstrate the stomatogenic significance, in particular in the initiation of oral membranelle assembly, of the gametic nuclei during sexual reproduction. The present study also suggests the possibility of micronuclear activities in the early part of the sexual cycle affecting postzygotic nucleogenesis.


1995 ◽  
Vol 4 (4) ◽  
pp. 300
Author(s):  
Billie G. Jeansonne
Keyword(s):  

Development ◽  
1984 ◽  
Vol 82 (1) ◽  
pp. 67-95
Author(s):  
Joseph Frankel ◽  
E. Marlo Nelsen ◽  
Julita Bakowska ◽  
Leslie M. Jenkins

The ciliary arrays of the oral apparatus of the ciliated protozoan Tetrahymena thermophila each have their own unique ‘pattern signature’, which varies little so long as the number of arrays remains the same. In this study, we analyse the consequence of increases in the number of these arrays (membranelles) brought about by certain mutations. In oral apparatuses of mutant cells, the addition of a membranelle is associated with specific alterations in at least one of the other membranelles. The features that are altered include the relative lengths of membranelles, the state of ciliation of basal bodies located at specific positions within these membranelles, and the spatial configurations resulting from displacement of ciliary units during late oral development. The final organization of each membranelle depends upon its relativeposition along the length of the oral apparatus. This indicates that the membranelles are not individually ‘named’ by the organism, and suggests that the unit of pattern organizationis the membranelle field as a whole. In the Discussion, we consider means for testing whether thesame underlying idea might also apply to multicellular systems, such as the vertebrate limb, in which spatially ordered differences appear to be superimposed upon a fundamental repeating pattern.


2019 ◽  
Vol 41 (6) ◽  
pp. 855-877 ◽  
Author(s):  
Hanjing Yu ◽  
Wander Lowie

Abstract The present study investigated the developmental patterns of Chinese EFL(AQ) learners’ oral language in terms of complexity and accuracy and looked into the dynamic interactions between them within the framework of Complex Dynamic Systems Theory (CDST). The data were analysed using dynamic analyses (moving min–max graphs, moving correlations and Monte Carlo Simulations). It was found that, firstly, at the group level, the general developmental trends of both complexity and accuracy showed improvements. Secondly, at the individual level, the developmental patterns were non-linear and dynamic with high degrees of variability, and individual language development was influenced by the initial states. Thirdly, the analyses revealed a complex interplay between complexity and accuracy, which gradually shifted from a clearly competitive relationship during the early stages to a supportive relationship in later stages. This shift in interaction shows that complexity goes hand in hand with accuracy, which corroborates the interconnectedness of subsystems as one of the major characteristics of CDST. The findings confirm the applicability of CDST approaches to L2 oral development and carry valuable implications for CDST theory development and oral language teaching.


2016 ◽  
Vol 12 (12) ◽  
pp. 90
Author(s):  
Farzaneh Amiri ◽  
Moomala Othman ◽  
Maryam Jahedi

This research used a qualitative approach to focus on the classroom debate between Malaysian English second language learners (ESL). Since debate has been often perceived as not a suitable activity for low proficiency students due to their limited linguistic resources, there has not been much emphasis on the impact of debate on incompetent ESL learners; however, this study was an attempt to concentrate on two students who were not competent in English to investigate their oral development via debate. The study observed the communicative strategies employed in this challenging task during the five debate rounds. Although the progress made was quite limited, the study showed that debate competition can be a relevant and meaningful practice for speaking activity among low proficiency students. Moreover, it showed that debate can be used to scaffold students’ practice in speaking.


SLEEP ◽  
2019 ◽  
Vol 42 (12) ◽  
Author(s):  
Christian Guilleminault ◽  
Yu-Shu Huang ◽  
Stacey Quo

Abstract Study Objectives Early in life impairment of orofacial growth leads to sleep-disordered breathing (SDB). Normal lingual gnosis and praxis are part of this early development related to the normal sensorimotor development of the tongue and surrounding oral musculature. The aim of this retrospective study was to explore if lingual praxia is impaired in both SDB children and adults and if there is an association to craniofacial morphology. Methods The ability to perform simple tongue maneuvers was investigated in 100 prepubertal SDB children and 150 SDB adults (shown with polysomnography). All individuals had a clinical investigation by specialists to assess any orofacial growth impairment and the elements potentially behind this impairment. In a subgroup of individuals both able and unable to perform the maneuvers, we also performed a blind recognition of forms placed in the mouth. Results A subgroup of pediatric and adult SDB patients presented evidence not only of orofacial growth impairment, but also apraxia independent of age and severity of OSA. Conclusions By 3 years of age, children should be able to perform requested tongue maneuvers and have oral form recognition. Abnormal gnosis–praxis was noted, independent of age in SDB children and adults, demonstrating that an abnormal functioning of the tongue in the oral cavity during early development can be detected. Both children and adults with SDB may present similar absences of normal oral development very early in life and a similar presentation of apraxia, suggesting that the distinction of SDB in children versus adults may not be relevant.


2011 ◽  
Vol 99 ◽  
pp. S212-S213
Author(s):  
S. Weston ◽  
J. Kingsley ◽  
D. Lidzey

2012 ◽  
Vol 67 (1-2) ◽  
pp. 58-64 ◽  
Author(s):  
Adriana Eliašová ◽  
Veronika Poracká ◽  
Peter Pal’ove-Balang ◽  
Ján Imrich ◽  
Miroslav Repčák

The new natural polyamine conjugate 1N,5N,10N,14N-tetracoumaroyl spermine (tetracoumaroyl spermine) recently isolated from chamomile (Matricaria chamomilla L.) flower heads is applicable for the treatment of several human disorders such as depression and anxiety. High variability in the level of tetracoumaroyl spermine is found in commercial tisanes. Accumulation of tetracoumaroyl spermine was tested during fl oral development, and nitrogen deficiency was chosen as its putative limiting environmental factor. It was observed that tetracoumaroyl spermine is present mainly in tubular flowers, reaching its maximal content during the 3rd phase of flowering when the corollae of tubular flowers start to open. The later observed decrease could result from a release of pollen that also contains a considerable amount of tetracoumaroyl spermine. It is likely that tetracoumaroyl spermine plays an important role in pollen development, and so, despite overall N-deficiency in the plants, tetracoumaroyl spermine is accumulated at the same or even higher rate than in the flowers of the N-sufficient control.


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